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JOHN STEELE

TitleInstructor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleInstructor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Precision Environmental Health
    DivisionCenter for Precision Env Health


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cao X, Xu J, Lin YL, Cabrera RM, Chen Q, Zhang C, Steele JW, Han X, Gross SS, Wlodarczyk BJ, Lupski JR, Li W, Wang H, Finnell RH, Lei Y. Excess folic acid intake increases DNA de novo point mutations. Cell Discov. 2023 Feb 28; 9(1):22. PMID: 36849450; PMCID: PMC9970956.
      Citations: 4     
    2. Steele JR, Jang SJ, Brilliant ZR, Mayman DJ, Sculco PK, Jerabek SA, Vigdorchik JM. Deep Learning Phenotype Automation and Cohort Analyses of 1,946 Knees Using the Coronal Plane Alignment of the Knee Classification. J Arthroplasty. 2023 06; 38(6S):S215-S221.e1. PMID: 36858128.
      Citations:    Fields:    Translation:Humans
    3. Steele JW, Lin YL, Chen N, Wlodarczyk BJ, Chen Q, Attarwala N, Venkatesalu M, Cabrera RM, Gross SS, Finnell RH. Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects. Front Cell Dev Biol. 2022; 10:832492. PMID: 35265619; PMCID: PMC8898900.
      Citations:    
    4. Wolujewicz P, Steele JW, Kaltschmidt JA, Finnell RH, Ross ME. Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back. Genesis. 2021 11; 59(11):e23459. PMID: 34713546; PMCID: PMC8851409.
      Citations: 2     Fields:    Translation:HumansAnimals
    5. Stevens LM, Kim G, Koromila T, Steele JW, McGehee J, Stathopoulos A, Stein DS. Light-dependent N-end rule-mediated disruption of protein function in Saccharomyces cerevisiae and Drosophila melanogaster. PLoS Genet. 2021 05; 17(5):e1009544. PMID: 33999957; PMCID: PMC8158876.
      Citations: 1     Fields:    Translation:AnimalsCells
    6. Finnell RH, Caiaffa CD, Kim SE, Lei Y, Steele J, Cao X, Tukeman G, Lin YL, Cabrera RM, Wlodarczyk BJ. Gene Environment Interactions in the Etiology of Neural Tube Defects. Front Genet. 2021; 12:659612. PMID: 34040637; PMCID: PMC8143787.
      Citations: 5     
    7. Tian T, Lai X, Xiang K, Han X, Yin S, Cabrera RM, Steele JW, Lei Y, Cao X, Finnell RH, Wang L, Ren A. Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects. Epigenetics. 2022 Jan-Feb; 17(2):133-146. PMID: 33491544; PMCID: PMC8865305.
      Citations:    Fields:    Translation:HumansCells
    8. Tian T, Cao X, Kim SE, Lin YL, Steele JW, Cabrera RM, Karki M, Yang W, Marini NJ, Hoffman EN, Han X, Hu C, Wang L, Wlodarczyk BJ, Shaw GM, Ren A, Finnell RH, Lei Y. FKBP8 variants are risk factors for spina bifida. Hum Mol Genet. 2020 11 04; 29(18):3132-3144. PMID: 32969478; PMCID: PMC7645715.
      Citations: 3     Fields:    Translation:HumansAnimals
    9. Keuls RA, Kojima K, Lozzi B, Steele JW, Chen Q, Gross SS, Finnell RH, Parchem RJ. MiR-302 Regulates Glycolysis to Control Cell-Cycle during Neural Tube Closure. Int J Mol Sci. 2020 Oct 13; 21(20). PMID: 33066028; PMCID: PMC7589003.
      Citations: 4     Fields:    Translation:AnimalsCells
    10. Cao X, Kim SE, Cabrera RM, Wlodarczyk BJ, Zhu H, Parker M, Lin Y, Steele JW, Han X, Finnell RH, Lei Y, Wolf A, Ramaekers VT, Steinfeld R. CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression. J Med Genet. 2021 07; 58(7):484-494. PMID: 32820034; PMCID: PMC7895856.
      Citations: 3     Fields:    Translation:HumansCells
    11. Steele JW, Kim SE, Finnell RH. One-carbon metabolism and folate transporter genes: Do they factor prominently in the genetic etiology of neural tube defects? Biochimie. 2020 Jun; 173:27-32. PMID: 32061804; PMCID: PMC7253344.
      Citations: 8     Fields:    Translation:Humans
    12. Cao X, Tian T, Steele JW, Cabrera RM, Aguiar-Pulido V, Wadhwa S, Bhavani N, Bi P, Gargurevich NH, Hoffman EN, Cai CQ, Marini NJ, Yang W, Shaw GM, Ross ME, Finnell RH, Lei Y. Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida. Hum Mutat. 2020 04; 41(4):786-799. PMID: 31898828; PMCID: PMC7185173.
      Citations: 8     Fields:    Translation:HumansCells
    13. Cabrera RM, Souder JP, Steele JW, Yeo L, Tukeman G, Gorelick DA, Finnell RH. The antagonism of folate receptor by dolutegravir: developmental toxicity reduction by supplemental folic acid. AIDS. 2019 11 01; 33(13):1967-1976. PMID: 31259764; PMCID: PMC6774845.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    14. Steele JW, Bayliss S, Bayliss J, Lin YL, Wlodarczyk BJ, Cabrera RM, Asfaw YG, Cummings TJ, Finnell RH, George TM. Heritable spina bifida in sheep: A potential model for fetal repair of myelomeningocele. J Pediatr Surg. 2020 Mar; 55(3):475-481. PMID: 31301886; PMCID: PMC6935438.
      Citations: 4     Fields:    Translation:Animals
    15. Knight EM, Kim SH, Kottwitz JC, Hatami A, Albay R, Suzuki A, Lublin A, Alberini CM, Klein WL, Szabo P, Relkin NR, Ehrlich M, Glabe CG, Gandy S, Steele JW. Effective anti-Alzheimer A? therapy involves depletion of specific A? oligomer subtypes. Neurol Neuroimmunol Neuroinflamm. 2016 Jun; 3(3):e237. PMID: 27218118; PMCID: PMC4864617.
      Citations: 23     Fields:    
    16. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Akematsu T, Akporiaye ET, Al-Rubeai M, Albanese C, Albani D, Albert ML, Aldudo J, Alirezaei M, Alloza I, Almasan A, Alnemri ES, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bao H, Barrachina MD, Barreiro E, Bartel B, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beck GR, Beckham JD, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernassola F, Bertolotti A, Bess AS, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bingol B, Bird SW, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Bonaldo P, Bordi M, Boulton ME, Bouret SG, Bozhkov PV, Brady N, Braga VM, Brancolini C, Brennan LA, Bresnick EH, Brest P, Bridges D, Brini M, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burke RE, Burmeister M, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Campanella M, Campbell GR, Campbell M, Campello S, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carroll B, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Cervia D, Cetrullo S, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clarke PG, Clarke R, Clementi E, Cnop M, Cocco T, Cohen EE, Colecchia D, Coletto L, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652; PMCID: PMC4835977.
      Citations: 2567     Fields:    Translation:HumansAnimals
    17. Steele JW, Brautigam H, Short JA, Sowa A, Shi M, Yadav A, Weaver CM, Westaway D, Fraser PE, St George-Hyslop PH, Gandy S, Hof PR, Dickstein DL. Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model. J Comp Neurol. 2014 Jul 01; 522(10):2319-35. PMID: 24415002; PMCID: PMC4251468.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    18. Sterns JD, Smith CB, Steele JR, Stevenson KL, Gallicano GI. Epigenetics and type II diabetes mellitus: underlying mechanisms of prenatal predisposition. Front Cell Dev Biol. 2014; 2:15. PMID: 25364722; PMCID: PMC4207047.
      Citations: 10     
    19. Steele JW, Gandy S. Latrepirdine (Dimebon?), a potential Alzheimer therapeutic, regulates autophagy and neuropathology in an Alzheimer mouse model. Autophagy. 2013 Apr; 9(4):617-8. PMID: 23380933; PMCID: PMC3627679.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
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