TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Biochemistry and Molecular Pharmacology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentTherapeutic Innovation Center
    DivisionTherapeutic Innovation Center

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bose R, Saleem I, Mustoe AM. Causes, functions, and therapeutic possibilities of RNA secondary structure ensembles and alternative states. Cell Chem Biol. 2024 01 18; 31(1):17-35. PMID: 38199037; PMCID: PMC10842484.
      Citations:    Fields:    Translation:HumansCells
    2. Mitchell D, Cotter J, Saleem I, Mustoe AM. Mutation signature filtering enables high-fidelity RNA structure probing at all four nucleobases with DMS. Nucleic Acids Res. 2023 09 08; 51(16):8744-8757. PMID: 37334863; PMCID: PMC10484685.
      Citations: 1     Fields:    Translation:Cells
    3. Mustoe AM, Weidmann CA, Weeks KM. Correction to "Single-Molecule Correlated Chemical Probing: A Revolution in RNA Structure Analysis". Acc Chem Res. 2023 Jun 20; 56(12):1684. PMID: 37283502.
      Citations:    Fields:    
    4. Mitchell D, Cotter J, Saleem I, Mustoe AM. Mutation signature filtering enables high-fidelity RNA structure probing at all four nucleobases with DMS. bioRxiv. 2023 Apr 11. PMID: 37090560; PMCID: PMC10120657.
    5. Mustoe AM, Weidmann CA, Weeks KM. Single-Molecule Correlated Chemical Probing: A Revolution in RNA Structure Analysis. Acc Chem Res. 2023 04 04; 56(7):763-775. PMID: 36917683; PMCID: PMC10078950.
      Citations: 3     Fields:    Translation:Cells
    6. Grayeski PJ, Weidmann CA, Kumar J, Lackey L, Mustoe AM, Busan S, Laederach A, Weeks KM. Global 5'-UTR RNA structure regulates translation of a SERPINA1 mRNA. Nucleic Acids Res. 2022 09 23; 50(17):9689-9704. PMID: 36107773; PMCID: PMC9508835.
    7. Dhindsa RS, Copeland BR, Mustoe AM, Goldstein DB. Natural Selection Shapes Codon Usage in the Human Genome. Am J Hum Genet. 2022 Aug 04; 109(8):1559. PMID: 35931054; PMCID: PMC9388379.
    8. Kumar J, Lackey L, Waldern JM, Dey A, Mustoe AM, Weeks KM, Mathews DH, Laederach A. Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing. Elife. 2022 06 13; 11. PMID: 35695373; PMCID: PMC9236610.
      Citations:    Fields:    Translation:Cells
    9. Olson SW, Turner AW, Arney JW, Saleem I, Weidmann CA, Margolis DM, Weeks KM, Mustoe AM. Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP. Mol Cell. 2022 05 05; 82(9):1708-1723.e10. PMID: 35320755; PMCID: PMC9081252.
      Citations: 1     Fields:    Translation:HumansCells
    10. Weidmann CA, Mustoe AM, Jariwala PB, Calabrese JM, Weeks KM. Analysis of RNA-protein networks with RNP-MaP defines functional hubs on RNA. Nat Biotechnol. 2021 03; 39(3):347-356. PMID: 33077962; PMCID: PMC7956044.
      Citations: 14     Fields:    Translation:HumansAnimals
    11. Dhindsa RS, Copeland BR, Mustoe AM, Goldstein DB. Natural Selection Shapes Codon Usage in the Human Genome. Am J Hum Genet. 2020 07 02; 107(1):83-95. PMID: 32516569; PMCID: PMC7332603.
      Citations: 16     Fields:    Translation:HumansCells
    12. Mustoe AM, Lama NN, Irving PS, Olson SW, Weeks KM. RNA base-pairing complexity in living cells visualized by correlated chemical probing. Proc Natl Acad Sci U S A. 2019 12 03; 116(49):24574-24582. PMID: 31744869; PMCID: PMC6900531.
      Citations: 32     Fields:    Translation:HumansCells
    13. Mustoe AM, Corley M, Laederach A, Weeks KM. Messenger RNA Structure Regulates Translation Initiation: A Mechanism Exploited from Bacteria to Humans. Biochemistry. 2018 07 03; 57(26):3537-3539. PMID: 29894169; PMCID: PMC6398326.
      Citations: 20     Fields:    Translation:HumansCells
    14. Mustoe AM, Busan S, Rice GM, Hajdin CE, Peterson BK, Ruda VM, Kubica N, Nutiu R, Baryza JL, Weeks KM. Pervasive Regulatory Functions of mRNA Structure Revealed by High-Resolution SHAPE Probing. Cell. 2018 03 22; 173(1):181-195.e18. PMID: 29551268; PMCID: PMC5866243.
      Citations: 97     Fields:    Translation:Cells
    15. Corley M, Solem A, Phillips G, Lackey L, Ziehr B, Vincent HA, Mustoe AM, Ramos SBV, Weeks KM, Moorman NJ, Laederach A. An RNA structure-mediated, posttranscriptional model of human a-1-antitrypsin expression. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):E10244-E10253. PMID: 29109288; PMCID: PMC5703279.
      Citations: 25     Fields:    Translation:HumansCells
    16. Daher M, Mustoe AM, Morriss-Andrews A, Brooks CL, Walter NG. Tuning RNA folding and function through rational design of junction topology. Nucleic Acids Res. 2017 09 19; 45(16):9706-9715. PMID: 28934478; PMCID: PMC5766210.
      Citations: 6     Fields:    Translation:Cells
    17. Krokhotin A, Mustoe AM, Weeks KM, Dokholyan NV. Direct identification of base-paired RNA nucleotides by correlated chemical probing. RNA. 2017 01; 23(1):6-13. PMID: 27803152; PMCID: PMC5159650.
      Citations: 17     Fields:    Translation:Cells
    18. Weidmann CA, Mustoe AM, Weeks KM. Direct Duplex Detection: An Emerging Tool in the RNA Structure Analysis Toolbox. Trends Biochem Sci. 2016 09; 41(9):734-736. PMID: 27427309; PMCID: PMC5002247.
      Citations: 11     Fields:    Translation:Cells
    19. Mustoe AM, Al-Hashimi HM, Brooks CL. Secondary structure encodes a cooperative tertiary folding funnel in the Azoarcus ribozyme. Nucleic Acids Res. 2016 Jan 08; 44(1):402-12. PMID: 26481360; PMCID: PMC4705646.
      Citations: 3     Fields:    Translation:Cells
    20. Mustoe AM, Liu X, Lin PJ, Al-Hashimi HM, Fierke CA, Brooks CL. Noncanonical secondary structure stabilizes mitochondrial tRNA(Ser(UCN)) by reducing the entropic cost of tertiary folding. J Am Chem Soc. 2015 Mar 18; 137(10):3592-9. PMID: 25705930; PMCID: PMC4399864.
      Citations: 10     Fields:    Translation:HumansCells
    21. Dickson A, Mustoe AM, Brooks CL, Salmon L. Efficient in silico exploration of RNA interhelical conformations using Euler angles and WExplore. Nucleic Acids Res. 2014 Oct 29; 42(19):12126-37. PMID: 25294827; PMCID: PMC4231733.
      Citations: 11     Fields:    Translation:Cells
    22. Mustoe AM, Brooks CL, Al-Hashimi HM. Topological constraints are major determinants of tRNA tertiary structure and dynamics and provide basis for tertiary folding cooperativity. Nucleic Acids Res. 2014 Oct; 42(18):11792-804. PMID: 25217593; PMCID: PMC4191394.
      Citations: 15     Fields:    Translation:Cells
    23. Ganser LR, Mustoe AM, Al-Hashimi HM. An RNA tertiary switch by modifying how helices are tethered. Genome Biol. 2014 Jul 30; 15(7):425. PMID: 25315677; PMCID: PMC4281957.
      Citations: 3     Fields:    Translation:Cells
    24. Mustoe AM, Brooks CL, Al-Hashimi HM. Hierarchy of RNA functional dynamics. Annu Rev Biochem. 2014; 83:441-66. PMID: 24606137; PMCID: PMC4048628.
      Citations: 74     Fields:    Translation:Cells
    25. Al-Hashimi HM, Brooks CL, Mustoe AM. Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges. J Phys Chem B. 2014 Mar 13; 118(10):2615-27. PMID: 24547945; PMCID: PMC3983386.
      Citations: 30     Fields:    Translation:Cells
    26. Suddala KC, Rinaldi AJ, Feng J, Mustoe AM, Eichhorn CD, Liberman JA, Wedekind JE, Al-Hashimi HM, Brooks CL, Walter NG. Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure. Nucleic Acids Res. 2013 Dec; 41(22):10462-75. PMID: 24003028; PMCID: PMC3905878.
      Citations: 46     Fields:    Translation:Cells
    27. Dethoff EA, Chugh J, Mustoe AM, Al-Hashimi HM. Functional complexity and regulation through RNA dynamics. Nature. 2012 Feb 15; 482(7385):322-30. PMID: 22337051; PMCID: PMC3320162.
      Citations: 147     Fields:    Translation:Cells
    28. Mustoe AM, Bailor MH, Teixeira RM, Brooks CL, Al-Hashimi HM. New insights into the fundamental role of topological constraints as a determinant of two-way junction conformation. Nucleic Acids Res. 2012 Jan; 40(2):892-904. PMID: 21937512; PMCID: PMC3258142.
      Citations: 26     Fields:    Translation:Cells
    29. Bailor MH, Mustoe AM, Brooks CL, Al-Hashimi HM. 3D maps of RNA interhelical junctions. Nat Protoc. 2011 Sep 15; 6(10):1536-45. PMID: 21959236; PMCID: PMC7737422.
      Citations: 31     Fields:    Translation:Cells
    30. Bailor MH, Mustoe AM, Brooks CL, Al-Hashimi HM. Topological constraints: using RNA secondary structure to model 3D conformation, folding pathways, and dynamic adaptation. Curr Opin Struct Biol. 2011 Jun; 21(3):296-305. PMID: 21497083; PMCID: PMC3319143.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
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