ATP Binding Cassette Transporter 1
"ATP Binding Cassette Transporter 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superfamily of large integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE characterized by accumulation of cholesteryl ester in various tissues.
| Descriptor ID |
D064286
|
| MeSH Number(s) |
D12.776.157.530.100.190.500 D12.776.395.550.020.381.500 D12.776.543.550.192.381.500 D12.776.543.585.100.190.500
|
| Concept/Terms |
ATP Binding Cassette Transporter 1- ATP Binding Cassette Transporter 1
- ATP-Binding Cassette Sub-Family A Member 1
- ATP Binding Cassette Sub Family A Member 1
- CERP Protein
- Protein, CERP
- ABCA1 Protein
- Protein, ABCA1
- Cholesterol-Efflux Regulatory Protein
- Cholesterol Efflux Regulatory Protein
- Protein, Cholesterol-Efflux Regulatory
- Regulatory Protein, Cholesterol-Efflux
|
Below are MeSH descriptors whose meaning is more general than "ATP Binding Cassette Transporter 1".
Below are MeSH descriptors whose meaning is more specific than "ATP Binding Cassette Transporter 1".
This graph shows the total number of publications written about "ATP Binding Cassette Transporter 1" by people in this website by year, and whether "ATP Binding Cassette Transporter 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "ATP Binding Cassette Transporter 1" by people in Profiles.
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Deletion of miR-33, a regulator of the ABCA1-APOE pathway, ameliorates neuropathological phenotypes in APP/PS1 mice. Alzheimers Dement. 2024 11; 20(11):7805-7818.
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Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nat Metab. 2020 10; 2(10):1135-1148.
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Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020 01 08; 28(1):202-216.
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Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response. Cell Stem Cell. 2019 02 07; 24(2):299-308.e6.
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Is RCT (Reverse Cholesterol Transport) Ready for an RCT (Randomized Controlled Trial)? J Am Coll Cardiol. 2018 12 25; 72(25):3270-3273.
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A novel mutation in the ABCA1 gene causing an atypical phenotype of Tangier disease. J Clin Lipidol. 2013 Jan-Feb; 7(1):82-7.
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Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter. Atherosclerosis. 2011 Sep; 218(1):77-82.
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Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells. J Nutr Biochem. 2011 Aug; 22(8):777-83.
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Regulation of cholesterol efflux by amyloid beta secretion. J Neurosci Res. 2010 Jul; 88(9):1985-94.
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Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in CARDIA participants. Arterioscler Thromb Vasc Biol. 2006 Aug; 26(8):1828-36.