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LAURA LOFTIS

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6621 FANNIN
Houston, TX 77030
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Medical Ethics and Health Policy
    DivisionCtr for Med Ethics & Health Policy


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rowan CM, LaBere B, Young CC, Zambrano LD, Newhams MM, Kucukak S, McNamara ER, Mack EH, Fitzgerald JC, Irby K, Maddux AB, Schuster JE, Kong M, Dapul H, Schwartz SP, Bembea MM, Loftis LL, Kolmar AR, Babbitt CJ, Nofziger RA, Hall MW, Gertz SJ, Cvijanovich NZ, Zinter MS, Halasa NB, Bradford TT, McLaughlin GE, Singh AR, Hobbs CV, Wellnitz K, Staat MA, Coates BM, Crandall HR, Maamari M, Havlin KM, Schwarz AJ, Carroll CL, Levy ER, Moffitt KL, Campbell AP, Randolph AG, Chou J, Overcoming COVID-19 Investigators. Pre-existing Immunocompromising Conditions and Outcomes of Acute COVID-19 Patients Admitted for Pediatric Intensive Care. Clin Infect Dis. 2024 Mar 11. PMID: 38465976.
      Citations:    Fields:    
    2. Maddux AB, Young CC, Kucukak S, Zambrano LD, Newhams MM, Rollins CK, Halasa NB, Gertz SJ, Mack EH, Schwartz S, Kong M, Loftis LL, Irby K, Rowan CM, Tarquinio KM, Zinter MS, Crandall H, Cvijanovich NZ, Schuster JE, Fitzgerald JC, Staat MA, Hobbs CV, Nofziger RA, Shein S, Flori H, Cullimore ML, Chatani BM, Levy ER, Typpo KV, Hume JR, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C. Front Pediatr. 2023; 11:1260372. PMID: 37920792; PMCID: PMC10619659.
      Citations: 1     
    3. Leland SB, Staffa SJ, Newhams MM, Khemani RG, Marshall JC, Young CC, Maddux AB, Hall MW, Weiss SL, Schwarz AJ, Coates BM, Sanders RC, Kong M, Thomas NJ, Nofziger RA, Cullimore ML, Halasa NB, Loftis LL, Cvijanovich NZ, Schuster JE, Flori H, Gertz SJ, Hume JR, Olson SM, Patel MM, Zurakowski D, Randolph AG, Pediatric Acute Lung and Sepsis Investigator?s Network Pediatric Intensive Care Influenza Study Grou. The Modified Clinical Progression Scale for Pediatric Patients: Evaluation as a Severity Metric and Outcome Measure in Severe Acute Viral Respiratory Illness. Pediatr Crit Care Med. 2023 Dec 01; 24(12):998-1009. PMID: 37539964; PMCID: PMC10688559.
      Citations:    Fields:    Translation:HumansCells
    4. Halasa N, Zambrano LD, Amarin JZ, Stewart LS, Newhams MM, Levy ER, Shein SL, Carroll CL, Fitzgerald JC, Michaels MG, Bline K, Cullimore ML, Loftis L, Montgomery VL, Jeyapalan AS, Pannaraj PS, Schwarz AJ, Cvijanovich NZ, Zinter MS, Maddux AB, Bembea MM, Irby K, Zerr DM, Kuebler JD, Babbitt CJ, Gaspers MG, Nofziger RA, Kong M, Coates BM, Schuster JE, Gertz SJ, Mack EH, White BR, Harvey H, Hobbs CV, Dapul H, Butler AD, Bradford TT, Rowan CM, Wellnitz K, Staat MA, Aguiar CL, Hymes SR, Randolph AG, Campbell AP, RSV-PIC Investigators. Infants Admitted to US Intensive Care Units for RSV Infection During the 2022 Seasonal Peak. JAMA Netw Open. 2023 08 01; 6(8):e2328950. PMID: 37581884; PMCID: PMC10427947.
      Citations: 2     Fields:    Translation:HumansCells
    5. Novak T, Crawford JC, Hahn G, Hall MW, Thair SA, Newhams MM, Chou J, Mourani PM, Tarquinio KM, Markovitz B, Loftis LL, Weiss SL, Higgerson R, Schwarz AJ, Pinto NP, Thomas NJ, Gedeit RG, Sanders RC, Mahapatra S, Coates BM, Cvijanovich NZ, Ackerman KG, Tellez DW, McQuillen P, Kurachek SC, Shein SL, Lange C, Thomas PG, Randolph AG. Transcriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza. Front Immunol. 2023; 14:1220028. PMID: 37533854; PMCID: PMC10390830.
      Citations:    Fields:    Translation:HumansCells
    6. Bembea MM, Loftis LL, Thiagarajan RR, Young CC, McCadden TP, Newhams MM, Kucukak S, Mack EH, Fitzgerald JC, Rowan CM, Maddux AB, Kolmar AR, Irby K, Heidemann S, Schwartz SP, Kong M, Crandall H, Havlin KM, Singh AR, Schuster JE, Hall MW, Wellnitz KA, Maamari M, Gaspers MG, Nofziger RA, Lim PPC, Carroll RW, Coronado Munoz A, Bradford TT, Cullimore ML, Halasa NB, McLaughlin GE, Pannaraj PS, Cvijanovich NZ, Zinter MS, Coates BM, Horwitz SM, Hobbs CV, Dapul H, Graciano AL, Butler AD, Patel MM, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Children and Adolescents With COVID-19 or Multisystem Inflammatory Syndrome Admitted to U.S. ICUs. Pediatr Crit Care Med. 2023 05 01; 24(5):356-371. PMID: 36995097; PMCID: PMC10153593.
      Citations:    Fields:    Translation:HumansCells
    7. Zambrano LD, Wu MJ, Martin L, Malloch L, Chen S, Newhams MM, Kucukak S, Son MB, Sanders C, Patterson K, Halasa N, Fitzgerald JC, Leroue MK, Hall M, Irby K, Rowan CM, Sahni LC, Loftis L, Bradford TT, Staat M, Babbitt C, Carroll CL, Kong M, Chou J, Patel MM, Randolph AG, Campbell AP, Hobbs CV, for the Overcoming COVID-19 investigators , Wellnitz K, Pannaraj PS, Schuster JE. Risk Factors for Multisystem Inflammatory Syndrome in Children: A Case-control Investigation. Pediatr Infect Dis J. 2023 06 01; 42(6):e190-e196. PMID: 37000922; PMCID: PMC10265536.
      Citations: 1     Fields:    Translation:HumansCells
    8. Moffitt KL, Nakamura MM, Young CC, Newhams MM, Halasa NB, Reed JN, Fitzgerald JC, Spinella PC, Soma VL, Walker TC, Loftis LL, Maddux AB, Kong M, Rowan CM, Hobbs CV, Schuster JE, Riggs BJ, McLaughlin GE, Michelson KN, Hall MW, Babbitt CJ, Cvijanovich NZ, Zinter MS, Maamari M, Schwarz AJ, Singh AR, Flori HR, Gertz SJ, Staat MA, Giuliano JS, Hymes SR, Clouser KN, McGuire J, Carroll CL, Thomas NJ, Levy ER, Randolph AG. Community-Onset Bacterial Coinfection in Children Critically Ill With Severe Acute Respiratory Syndrome Coronavirus 2 Infection. Open Forum Infect Dis. 2023 Mar; 10(3):ofad122. PMID: 36968962; PMCID: PMC10034750.
      Citations:    
    9. Soma VL, Pediatric Intensive Care Influenza, Overcoming COVID-19 Investigators, Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG. Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children. Clin Infect Dis. 2023 02 08; 76(3):e280-e290. PMID: 35717646; PMCID: PMC9384330.
      Citations:    Fields:    
    10. LaRovere KL, Poussaint TY, Young CC, Newhams MM, Kucukak S, Irby K, Kong M, Schwartz SP, Walker TC, Bembea MM, Wellnitz K, Havlin KM, Cvijanovich NZ, Hall MW, Fitzgerald JC, Schuster JE, Hobbs CV, Halasa NB, Singh AR, Mack EH, Bradford TT, Gertz SJ, Schwarz AJ, Typpo KV, Loftis LL, Giuliano JS, Horwitz SM, Biagas KV, Clouser KN, Rowan CM, Maddux AB, Soma VL, Babbitt CJ, Aguiar CL, Kolmar AR, Heidemann SM, Harvey H, Zambrano LD, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2023 01 01; 80(1):91-98. PMID: 36342679; PMCID: PMC9641594.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    11. Schwartz SP, Walker TC, Mack EH, Gertz SJ, Bodansky A, Vazquez SE, Chou J, Novak T, Al-Musa A, Young C, Newhams M, Kucukak S, Zambrano LD, Mitchell A, Wang CY, Moffitt K, Halasa NB, Loftis LL, Fitzgerald JC, Rowan CM, Irby K, Sanders RC, Kong M, Schuster JE, Staat MA, Zinter MS, Cvijanovich NZ, Tarquinio KM, Coates BM, Flori HR, Dahmer MK, Crandall H, Cullimore ML, Levy ER, Chatani B, Nofziger R, Overcoming COVID-19 Network Study Group Investigators,, Geha RS, DeRisi J, Campbell AP, Anderson M, Randolph AG. NFKB2 haploinsufficiency identified via screening for IFN-a2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2-related complications. J Allergy Clin Immunol. 2023 04; 151(4):926-930.e2. PMID: 36509151; PMCID: PMC9733962.
      Citations: 5     Fields:    Translation:HumansCells
    12. Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Pediatric Intensive Care Influenza (PI. DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 11 28; 226(11):2030-2036. PMID: 35986912; PMCID: PMC10205622.
      Citations:    
    13. Dionne A, Friedman KG, Young CC, Newhams MM, Kucukak S, Jackson AM, Fitzgerald JC, Smallcomb LS, Heidemann S, McLaughlin GE, Irby K, Bradford TT, Horwitz SM, Loftis LL, Soma VL, Rowan CM, Kong M, Halasa NB, Tarquinio KM, Schwarz AJ, Hume JR, Gertz SJ, Clouser KN, Carroll CL, Wellnitz K, Cullimore ML, Doymaz S, Levy ER, Typpo KV, Lansell AN, Butler AD, Kuebler JD, Zambrano LD, Campbell AP, Patel MM, Randolph AG, Newburger JW, Overcoming COVID-19 Investigators. Tachyarrhythmias During Hospitalization for COVID-19 or Multisystem Inflammatory Syndrome in Children and Adolescents. J Am Heart Assoc. 2022 10 18; 11(20):e025915. PMID: 36250670; PMCID: PMC9673680.
      Citations: 3     Fields:    Translation:Humans
    14. Sigal GB, Novak T, Mathew A, Chou J, Zhang Y, Manjula N, Bathala P, Joe J, Padmanabhan N, Romero D, Allegri-Machado G, Joerger J, Loftis LL, Schwartz SP, Walker TC, Fitzgerald JC, Tarquinio KM, Zinter MS, Schuster JE, Halasa NB, Cullimore ML, Maddux AB, Staat MA, Irby K, Flori HR, Coates BM, Crandall H, Gertz SJ, Randolph AG, Pollock NR, Overcoming COVID-19 Investigators. Measurement of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens in Plasma of Pediatric Patients With Acute Coronavirus Disease 2019 or Multisystem Inflammatory Syndrome in Children Using an Ultrasensitive and Quantitative Immunoassay. Clin Infect Dis. 2022 10 12; 75(8):1351-1358. PMID: 35213684; PMCID: PMC8903440.
      Citations: 3     Fields:    
    15. Maddux AB, Berbert L, Young CC, Feldstein LR, Zambrano LD, Kucukak S, Newhams MM, Miller K, FitzGerald MM, He J, Halasa NB, Cvijanovich NZ, Loftis LL, Walker TC, Schwartz SP, Gertz SJ, Tarquinio KM, Fitzgerald JC, Kong M, Schuster JE, Mack EH, Hobbs CV, Rowan CM, Staat MA, Zinter MS, Irby K, Crandall H, Flori H, Cullimore ML, Nofziger RA, Shein SL, Gaspers MG, Hume JR, Levy ER, Chen SR, Patel MM, Tenforde MW, Weller E, Campbell AP, Randolph AG, Overcoming COVID-19 Investigators. Health Impairments in Children and Adolescents After Hospitalization for Acute COVID-19 or MIS-C. Pediatrics. 2022 09 01; 150(3). PMID: 35765138; PMCID: PMC10281852.
      Citations:    Fields:    
    16. Dante SA, Carroll MK, Ng DK, Patel A, Spinella PC, Steiner ME, Loftis LL, Bembea MM, Pediatric ECMO (PediECMO) subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALI. Extracorporeal Membrane Oxygenation Outcomes in Children With Preexisting Neurologic Disorders or Neurofunctional Disability. Pediatr Crit Care Med. 2022 11 01; 23(11):881-892. PMID: 36000833; PMCID: PMC9633375.
      Citations:    
    17. Tang J, Novak T, Hecker J, Grubbs G, Zahra FT, Bellusci L, Pourhashemi S, Chou J, Moffitt K, Halasa NB, Schwartz SP, Walker TC, Tarquinio KM, Zinter MS, Staat MA, Gertz SJ, Cvijanovich NZ, Schuster JE, Loftis LL, Coates BM, Mack EH, Irby K, Fitzgerald JC, Rowan CM, Kong M, Flori HR, Maddux AB, Shein SL, Crandall H, Hume JR, Hobbs CV, Tremoulet AH, Shimizu C, Burns JC, Chen SR, Moon HK, Lange C, Randolph AG, Khurana S. Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 Aug 12; 13(1):4732. PMID: 35961980; PMCID: PMC9372969.
      Citations:    
    18. Schuster JE, Halasa NB, Nakamura M, Levy ER, Fitzgerald JC, Young CC, Newhams MM, Bourgeois F, Staat MA, Hobbs CV, Dapul H, Feldstein LR, Jackson AM, Mack EH, Walker TC, Maddux AB, Spinella PC, Loftis LL, Kong M, Rowan CM, Bembea MM, McLaughlin GE, Hall MW, Babbitt CJ, Maamari M, Zinter MS, Cvijanovich NZ, Michelson KN, Gertz SJ, Carroll CL, Thomas NJ, Giuliano JS, Singh AR, Hymes SR, Schwarz AJ, McGuire JK, Nofziger RA, Flori HR, Clouser KN, Wellnitz K, Cullimore ML, Hume JR, Patel M, Randolph AG, Overcoming COVID-19 Investigators. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 May 30; 11(5):191-198. PMID: 35022779; PMCID: PMC8807297.
      Citations:    Fields:    Translation:Humans
    19. Tang J, Novak T, Hecker J, Grubbs G, Zahra FT, Bellusci L, Pourhashemi S, Chou J, Moffitt K, Halasa NB, Schwartz SP, Walker TC, Tarquinio KM, Zinter MS, Staat MA, Gertz SJ, Cvijanovich NZ, Schuster JE, Loftis LL, Coates BM, Mack EH, Irby K, Fitzgerald JC, Rowan CM, Kong M, Flori HR, Maddux AB, Shein SL, Crandall H, Hume JR, Hobbs CV, Tremoulet AH, Shimizu C, Burns JC, Chen SR, Moon HK, Lange C, Randolph AG, Khurana S. Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 05 27; 13(1):2979. PMID: 35624101; PMCID: PMC9142524.
      Citations:    Fields:    Translation:HumansCells
    20. Alcamo AM, Weiss SL, Fitzgerald JC, Kirschen MP, Loftis LL, Tang SF, Thomas NJ, Nadkarni VM, Nett ST, Sepsis Prevalence, Outcomes and Therapies (SPROUT) Study Investigators and Pediatric Acute Lung Inju. Outcomes Associated With Timing of Neurologic Dysfunction Onset Relative to Pediatric Sepsis Recognition. Pediatr Crit Care Med. 2022 08 01; 23(8):593-605. PMID: 36165937; PMCID: PMC9524404.
      Citations:    Fields:    Translation:Humans
    21. Rowan CM, Smith L, Sharron MP, Loftis L, Kudchadkar S, Duncan CN, Pike F, Carpenter PA, Jacobsohn D, Bollard CM, Cruz CRY, Malatpure A, Farag S, Renbarger J, Little MR, Gafken PR, Krance RA, Cooke KR, Paczesny S. A biomarker panel for risk of early respiratory failure following hematopoietic cell transplantation. Blood Adv. 2022 03 22; 6(6):1866-1878. PMID: 35139145; PMCID: PMC8941462.
      Citations:    Fields:    Translation:Humans
    22. Hobbs CV, Woodworth K, Young CC, Jackson AM, Newhams MM, Dapul H, Maamari M, Hall MW, Maddux AB, Singh AR, Schuster JE, Rowan CM, Fitzgerald JC, Irby K, Kong M, Mack EH, Staat MA, Cvijanovich NZ, Bembea MM, Coates BM, Halasa NB, Walker TC, McLaughlin GE, Babbitt CJ, Nofziger RA, Loftis LL, Bradford TT, Campbell AP, Patel MM, Randolph AG, for the Overcoming COVID-19 Investigators . Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2022 03 01; 41(3):e81-e86. PMID: 34955519; PMCID: PMC8828316.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    23. Tang J, Randolph AG, Novak T, Walker TC, Loftis LL, Zinter MS, Irby K, Khurana S. Systemic and Lower Respiratory Tract Immunity to SARS-CoV-2 Omicron and Variants in Pediatric Severe COVID-19 and Mis-C. Vaccines (Basel). 2022 Feb 10; 10(2). PMID: 35214728; PMCID: PMC8879098.
      Citations:    
    24. Sigal GB, Novak T, Mathew A, Chou J, Zhang Y, Manjula N, Bathala P, Joe J, Padmanabhan N, Romero D, Allegri-Machado G, Joerger J, Loftis LL, Schwartz SP, Walker TC, Fitzgerald JC, Tarquinio KM, Zinter MS, Schuster JE, Halasa NB, Cullimore ML, Maddux AB, Staat MA, Irby K, Flori HR, Coates BM, Crandall H, Gertz SJ, Randolph AG, Pollock NR. Measurement of SARS-CoV-2 antigens in plasma of pediatric patients with acute COVID-19 or MIS-C using an ultrasensitive and quantitative immunoassay. medRxiv. 2021 Dec 09. PMID: 34909787; PMCID: PMC8669854.
      Citations: 1     
    25. Pinto VL, Guffey D, Loftis L, Bembea MM, Spinella PC, Hanson SJ. Evaluation of Severity of Illness Scores in the Pediatric ECMO Population. Front Pediatr. 2021; 9:698120. PMID: 34650938; PMCID: PMC8506160.
      Citations:    
    26. Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, Overcoming COVID-19 Investigators. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40:101112. PMID: 34485878; PMCID: PMC8405351.
      Citations: 8     
    27. Smith M, Bell C, Vega MW, Tufan Pekkucuksen N, Loftis L, McPherson M, Graf J, Akcan Arikan A. Patient-centered outcomes in pediatric continuous kidney replacement therapy: new morbidity and worsened functional status in survivors. Pediatr Nephrol. 2022 01; 37(1):189-197. PMID: 34235579; PMCID: PMC8263014.
      Citations: 2     Fields:    Translation:Humans
    28. Killien EY, Loftis LL, Clark JD, Muszynski JA, Rissmiller BJ, Singleton MN, White BR, Zimmerman JJ, Maddux AB, Pinto NP, Fink EL, Watson RS, Smith M, Ringwood M, Graham RJ, POST-PICU?and PICU-COS Investigators of the Pediatric Acute Lung Injury?and Sepsis Investigators?and. Health-related quality of life outcome measures for children surviving critical care: a scoping review. Qual Life Res. 2021 Dec; 30(12):3383-3394. PMID: 34185224; PMCID: PMC9116894.
      Citations: 2     Fields:    Translation:Humans
    29. Son MBF, Murray N, Friedman K, Young CC, Newhams MM, Feldstein LR, Loftis LL, Tarquinio KM, Singh AR, Heidemann SM, Soma VL, Riggs BJ, Fitzgerald JC, Kong M, Doymaz S, Giuliano JS, Keenaghan MA, Hume JR, Hobbs CV, Schuster JE, Clouser KN, Hall MW, Smith LS, Horwitz SM, Schwartz SP, Irby K, Bradford TT, Maddux AB, Babbitt CJ, Rowan CM, McLaughlin GE, Yager PH, Maamari M, Mack EH, Carroll CL, Montgomery VL, Halasa NB, Cvijanovich NZ, Coates BM, Rose CE, Newburger JW, Patel MM, Randolph AG, Overcoming COVID-19 Investigators. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 07 01; 385(1):23-34. PMID: 34133855; PMCID: PMC8220972.
      Citations: 69     Fields:    Translation:HumansPHPublic Health
    30. LaRovere KL, Riggs BJ, Poussaint TY, Young CC, Newhams MM, Maamari M, Walker TC, Singh AR, Dapul H, Hobbs CV, McLaughlin GE, Son MBF, Maddux AB, Clouser KN, Rowan CM, McGuire JK, Fitzgerald JC, Gertz SJ, Shein SL, Munoz AC, Thomas NJ, Irby K, Levy ER, Staat MA, Tenforde MW, Feldstein LR, Halasa NB, Giuliano JS, Hall MW, Kong M, Carroll CL, Schuster JE, Doymaz S, Loftis LL, Tarquinio KM, Babbitt CJ, Nofziger RA, Kleinman LC, Keenaghan MA, Cvijanovich NZ, Spinella PC, Hume JR, Wellnitz K, Mack EH, Michelson KN, Flori HR, Patel MM, Randolph AG, Overcoming COVID-19 Investigators. Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome. JAMA Neurol. 2021 05 01; 78(5):536-547. PMID: 33666649; PMCID: PMC7936352.
      Citations: 81     Fields:    Translation:Humans
    31. Casas J, Jeppesen A, Peters L, Schuelke T, Magdoza NRK, Hesselgrave J, Loftis L. Using Quality Improvement Science to Create a Navigator in the Electronic Health Record for the Consolidation of Patient Information Surrounding Pediatric End-of-Life Care. J Pain Symptom Manage. 2021 09; 62(3):e218-e224. PMID: 33864845.
      Citations:    Fields:    Translation:Humans
    32. Jaber B, Bembea MM, Loftis LL, Spinella PC, Zhang L, Simpson PM, Hanson SJ, the Pediatric ECMO (PediECMO) Subgroup of the Pediatric Acute Lung . Venovenous Versus Venoarterial Extracorporeal Membranous Oxygenation in Inotrope Dependent Pediatric Patients With Respiratory Failure. ASAIO J. 2021 04 01; 67(4):457-462. PMID: 33770001.
      Citations: 1     Fields:    Translation:Humans
    33. Feldstein LR, Tenforde MW, Friedman KG, Newhams M, Rose EB, Dapul H, Soma VL, Maddux AB, Mourani PM, Bowens C, Maamari M, Hall MW, Riggs BJ, Giuliano JS, Singh AR, Li S, Kong M, Schuster JE, McLaughlin GE, Schwartz SP, Walker TC, Loftis LL, Hobbs CV, Halasa NB, Doymaz S, Babbitt CJ, Hume JR, Gertz SJ, Irby K, Clouser KN, Cvijanovich NZ, Bradford TT, Smith LS, Heidemann SM, Zackai SP, Wellnitz K, Nofziger RA, Horwitz SM, Carroll RW, Rowan CM, Tarquinio KM, Mack EH, Fitzgerald JC, Coates BM, Jackson AM, Young CC, Son MBF, Patel MM, Newburger JW, Randolph AG, Overcoming COVID-19 Investigators. Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19. JAMA. 2021 03 16; 325(11):1074-1087. PMID: 33625505; PMCID: PMC7905703.
      Citations: 174     Fields:    Translation:Humans
    34. O'Neil ER, Akcan Arikan A, Buffone GJ, Loftis LL, Cruz AT, Devaraj S. Passive acute kidney injury alerts: less is not more. Pediatr Res. 2021 09; 90(3):496-498. PMID: 33446923.
      Citations:    Fields:    Translation:Humans
    35. Maddux AB, Pinto N, Fink EL, Hartman ME, Nett S, Biagas K, Killien EY, Dervan LA, Christie LM, Luckett PM, Loftis L, Lackey M, Ringwood M, Smith M, Olson L, Sorenson S, Meert KL, Notterman DA, Pollack MM, Mourani PM, Watson RS, Pediatric Outcomes STudies after PICU (POST-PICU) and PICU-COS Investigators of the Pediatric Acute . Postdischarge Outcome Domains in Pediatric Critical Care and the Instruments Used to Evaluate Them: A Scoping Review. Crit Care Med. 2020 12; 48(12):e1313-e1321. PMID: 33009099; PMCID: PMC7708523.
      Citations: 19     Fields:    Translation:Humans
    36. Ettinger NA, Coleman RD, Loftis LL. Pediatric Intensivists Reply to "Can a Parent Refuse the Brain Death Examination?" Pediatrics. 2020 09; 146(3). PMID: 32868468.
      Citations:    Fields:    Translation:Humans
    37. Keim G, Yehya N, Spear D, Hall MW, Loftis LL, Alten JA, McArthur J, Patwari PP, Freishtat RJ, Willson DF, Straumanis JP, Thomas NJ, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure. Crit Care Med. 2020 08; 48(8):1120-1128. PMID: 32697481; PMCID: PMC7490803.
      Citations: 6     Fields:    Translation:Humans
    38. Steppan DA, Coleman RD, Viamonte HK, Hanson SJ, Carroll MK, Klein OR, Cooke KR, Spinella PC, Steiner ME, Loftis LL, Bembea MM, Pediatric ECMO (PediECMO) subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALI. Outcomes of pediatric patients with oncologic disease or following hematopoietic stem cell transplant supported on extracorporeal membrane oxygenation: The PEDECOR experience. Pediatr Blood Cancer. 2020 10; 67(10):e28403. PMID: 32519430.
      Citations: 9     Fields:    Translation:Humans
    39. Downey R, McElvain D, Murphey DK, Bailey A, Patel B, Fernandez M, Loftis L, Carreno CG, Eger L, Aguilera E, Wootton S, Castignini L, Hauger SB. Reply to Maadan et?al. Pediatr Neurol. 2020 09; 110:102-103. PMID: 32731961.
      Citations:    Fields:    Translation:Humans
    40. Coleman RD, Goldman J, Moffett B, Guffey D, Loftis L, Thomas J, Shekerdemian LS. Extracorporeal Membrane Oxygenation Mortality in High-Risk Populations: An Analysis of the Pediatric Health Information System Database. ASAIO J. 2020 03; 66(3):327-331. PMID: 31045920.
      Citations: 4     Fields:    Translation:Humans
    41. Downey R, McElvain D, Murphey DK, Bailey A, Patel B, Fernandez M, Loftis L, Carreno CG, Eger L, Aguilera EA, Wootton S, Castagnini LA, Hauger SB. Acute Flaccid Myelitis Among Hospitalized Children in Texas, 2016. Pediatr Neurol. 2020 05; 106:50-55. PMID: 32192819.
      Citations: 2     Fields:    Translation:Humans
    42. Novak T, Hall MW, McDonald DR, Newhams MM, Mistry AJ, Panoskaltsis-Mortari A, Mourani PM, Loftis LL, Weiss SL, Tarquinio KM, Markovitz B, Hartman ME, Schwarz A, Junger WG, Randolph AG, PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators. RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness. J Allergy Clin Immunol. 2020 06; 145(6):1673-1680.e11. PMID: 32035159; PMCID: PMC7323584.
      Citations: 2     Fields:    Translation:HumansCells
    43. Nellis ME, Tucci M, Lacroix J, Spinella PC, Haque KD, Stock A, Steiner ME, Faustino EVS, Zantek ND, Davis PJ, Stanworth SJ, Cholette JM, Parker RI, Kneyber MCJ, Russell RT, Stricker PA, Vogel AM, Willems A, Josephson CD, Luban NLC, Loftis LL, Stocker CF, Goobie SM, Karam O, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network; and the Pediatric Critical Ca, Demaret P, Leteurtre S. Bleeding Assessment Scale in Critically Ill Children (BASIC): Physician-Driven Diagnostic Criteria for Bleeding Severity. Crit Care Med. 2019 12; 47(12):1766-1772. PMID: 31567407; PMCID: PMC6861687.
      Citations: 8     Fields:    Translation:Humans
    44. Ruth A, Meador M, Hui R, Loftis L, Teruya J. Acquired von Willebrand Syndrome in Pediatric Extracorporeal Membrane Oxygenation Patients: A Single Institution's Experience. Pediatr Crit Care Med. 2019 10; 20(10):980-985. PMID: 31246745.
      Citations: 1     Fields:    Translation:Humans
    45. O'Neil ER, Devaraj S, Mayorquin L, Starke HE, Buffone GJ, Loftis LL, Arikan AA, Cruz AT. Defining pediatric community-acquired acute kidney injury: an observational study. Pediatr Res. 2020 02; 87(3):564-568. PMID: 31537011.
      Citations: 1     Fields:    Translation:Humans
    46. Levy ER, Yip WK, Super M, Ferdinands JM, Mistry AJ, Newhams MM, Zhang Y, Su HC, McLaughlin GE, Sapru A, Loftis LL, Weiss SL, Hall MW, Cvijanovich N, Schwarz A, Tarquinio KM, Mourani PM, PALISI PICFLU Investigators, Randolph AG. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10:1005. PMID: 31139182; PMCID: PMC6518443.
      Citations:    Fields:    Translation:HumansCellsCTClinical Trials
    47. Musick MA, Loftis LL, Kennedy CE. Comparing Vasoactive-Inotropic Score Reporting Strategies in the PICU Relative to Mortality Risk. Pediatr Crit Care Med. 2018 12; 19(12):1130-1136. PMID: 30520839.
      Citations: 4     Fields:    Translation:Humans
    48. Erklauer J, Graf J, McPherson M, Anderson A, Wilfong A, Minard CG, Loftis L. Outcomes in Children Treated with Pentobarbital Infusion for Refractory and Super-Refractory Status Epilepticus. Neurocrit Care. 2018 10; 29(2):171-179. PMID: 29582225.
      Citations: 1     Fields:    Translation:Humans
    49. Cruz AT, Buffone GJ, Devaraj S, Bernardo EO, Loftis LL, Arikan AA. Community-acquired Acute Kidney Injury Among Children Seen in the Pediatric Emergency Department. Acad Emerg Med. 2018 07; 25(7):758-768. PMID: 29630763.
      Citations: 2     Fields:    Translation:Humans
    50. Akcan-Arikan A, Gebhard DJ, Arnold MA, Loftis LL, Kennedy CE. Fluid Overload and Kidney Injury Score: A Multidimensional Real-Time Assessment of Renal Disease Burden in the Critically Ill Patient. Pediatr Crit Care Med. 2017 Jun; 18(6):524-530. PMID: 28406863.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    51. Blumenthal-Barby JS, Loftis L, Cummings CL, Meadow W, Lemmon M, Ubel PA, McCullough L, Rao E, Lantos JD. Should Neonatologists Give Opinions Withdrawing Life-sustaining Treatment? Pediatrics. 2016 12; 138(6). PMID: 27940720.
      Citations: 3     Fields:    Translation:Humans
    52. Randolph AG, Agan AA, Flanagan RF, Meece JK, Fitzgerald JC, Loftis LL, Truemper EJ, Li S, Ferdinands JM, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) PICFlu Study Group. Optimizing Virus Identification in Critically Ill Children Suspected of Having an Acute Severe Viral Infection. Pediatr Crit Care Med. 2016 Apr; 17(4):279-86. PMID: 26895562.
      Citations: 4     Fields:    Translation:HumansCells
    53. Nguyen T, Kyle UG, Jaimon N, Tcharmtchi MH, Coss-Bu JA, Lam F, Teruya J, Loftis L. Coinfection with Staphylococcus aureus increases risk of severe coagulopathy in critically ill children with influenza A (H1N1) virus infection. Crit Care Med. 2012 Dec; 40(12):3246-50. PMID: 22971587; PMCID: PMC3502679.
      Citations: 20     Fields:    Translation:HumansCells
    54. Arikan AA, Zappitelli M, Goldstein SL, Naipaul A, Jefferson LS, Loftis LL. Fluid overload is associated with impaired oxygenation and morbidity in critically ill children. Pediatr Crit Care Med. 2012 May; 13(3):253-8. PMID: 21760565.
      Citations: 106     Fields:    Translation:Humans
    55. Randolph AG, Vaughn F, Sullivan R, Rubinson L, Thompson BT, Yoon G, Smoot E, Rice TW, Loftis LL, Helfaer M, Doctor A, Paden M, Flori H, Babbitt C, Graciano AL, Gedeit R, Sanders RC, Giuliano JS, Zimmerman J, Uyeki TM, Pediatric Acute Lung Injury and Sepsis Investigator's Network and the National Heart, Lung, and Bloo. Critically ill children during the 2009-2010 influenza pandemic in the United States. Pediatrics. 2011 Dec; 128(6):e1450-8. PMID: 22065262; PMCID: PMC3387899.
      Citations: 105     Fields:    Translation:HumansCellsPHPublic Health
    56. Bilen O, Loftis L, Teruya J. Severe thrombotic and bleeding complications in a baby with heterozygous factor V Leiden and acquired von Willebrand disease on ECMO. J Extra Corpor Technol. 2011 Jun; 43(2):64-9. PMID: 21848174; PMCID: PMC4680025.
      Citations:    Fields:    Translation:HumansCells
    57. Washburn KK, Zappitelli M, Arikan AA, Loftis L, Yalavarthy R, Parikh CR, Edelstein CL, Goldstein SL. Urinary interleukin-18 is an acute kidney injury biomarker in critically ill children. Nephrol Dial Transplant. 2008 Feb; 23(2):566-72. PMID: 17911094.
      Citations: 66     Fields:    Translation:Humans
    58. Ream RS, Mackey K, Leet T, Green MC, Andreone TL, Loftis LL, Lynch RE. Association of nursing workload and unplanned extubations in a pediatric intensive care unit. Pediatr Crit Care Med. 2007 Jul; 8(4):366-71. PMID: 17545927.
      Citations: 10     Fields:    Translation:Humans
    59. Zappitelli M, Washburn KK, Arikan AA, Loftis L, Ma Q, Devarajan P, Parikh CR, Goldstein SL. Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study. Crit Care. 2007; 11(4):R84. PMID: 17678545; PMCID: PMC2206519.
      Citations: 166     Fields:    Translation:Humans
    60. Loftis L. Acute infectious upper airway obstructions in children. Semin Pediatr Infect Dis. 2006 Jan; 17(1):5-10. PMID: 16522499.
      Citations: 5     Fields:    Translation:Humans
    61. Matuschak GM, Lechner AJ, Chen Z, Todi S, Doyle TM, Loftis LL. Hypoxic suppression of E. coli-induced NF-kappa B and AP-1 transactivation by oxyradical signaling. Am J Physiol Regul Integr Comp Physiol. 2004 Aug; 287(2):R437-45. PMID: 15059791.
      Citations: 4     Fields:    Translation:AnimalsCells
    62. Geller T, Loftis L, Brink DS. Cerebellar infarction in adolescent males associated with acute marijuana use. Pediatrics. 2004 Apr; 113(4):e365-70. PMID: 15060269.
      Citations: 18     Fields:    Translation:Humans
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