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RICHARD LLOYD

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Virology & Microbiology
AddressOne Baylor Plaza
Houston, TX 77030
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    Collapse Research 
    Collapse research activities and funding
    R01DK124581     (LLOYD, RICHARD E)Aug 20, 2020 - Jun 30, 2024
    NIH
    Gut Viral and Bacterial Associations with Celiac Disease in the TEDDY Cohort
    Role: Principal Investigator
    R21AI132985     (RAMANI, SASIREKHA)Aug 9, 2018 - Jul 31, 2021
    NIH
    Oral vaccine interactions in human intestinal enteroids
    Role: Co-Principal Investigator
    R01AI050237     (LLOYD, RICHARD E)Jul 1, 2001 - Jun 30, 2023
    NIH
    Translation Regulation by Enterovirus Proteinase
    Role: Principal Investigator
    R56AI050237     (LLOYD, RICHARD E)Jul 1, 2001 - Dec 14, 2007
    NIH
    Translation Regulation by Enterovirus Proteinase
    Role: Principal Investigator
    R01GM059803     (LLOYD, RICHARD E)Aug 1, 1999 - Aug 31, 2009
    NIH
    Mechanisms of Translation Control During Apoptosis
    Role: Principal Investigator
    R01AI027914     (LLOYD, RICHARD E)Aug 1, 1989 - Nov 30, 2000
    NIH
    CONTROL OF TRANSLATION BY POLIOVIRUS PROTEINASE
    Role: Principal Investigator
    F32AI007085     (LLOYD, RICHARD E)Jul 1, 1985
    NIH
    POLIOVIRUS ACTIVATION OF HOST P220-SPECIFIC PROTEINASE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lin J, Moradi E, Salenius K, Lehtipuro S, H?kkinen T, Laiho JE, Oikarinen S, Randelin S, Parikh HM, Krischer JP, Toppari J, Lernmark ?, Petrosino JF, Ajami NJ, She JX, Hagopian WA, Rewers MJ, Lloyd RE, Rautajoki KJ, Hy?ty H, Nykter M, TEDDY Study Group. Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection. Nat Commun. 2023 Nov 22; 14(1):7630. PMID: 37993433; PMCID: PMC10665402.
      Citations:    Fields:    Translation:HumansCells
    2. Tisza M, Lloyd R, Hoffman K, Smith D, Rewers M, TEDDY Study Group, Cregeen SJ, Petrosino JF. Phage-bacteria dynamics during the first years of life revealed by trans-kingdom marker gene analysis. bioRxiv. 2023 Sep 29. PMID: 37808738; PMCID: PMC10557657.
      Citations:    
    3. Deater M, Tamhankar M, Lloyd RE. TDRD3 is an antiviral restriction factor that promotes IFN signaling with G3BP1. PLoS Pathog. 2022 01; 18(1):e1010249. PMID: 35085371; PMCID: PMC8824378.
      Citations: 1     Fields:    Translation:HumansCells
    4. Lloyd RE, Tamhankar M, Lernmark ?. Enteroviruses and Type 1 Diabetes: Multiple Mechanisms and Factors? Annu Rev Med. 2022 01 27; 73:483-499. PMID: 34794324; PMCID: PMC9242008.
      Citations: 1     Fields:    Translation:HumansCells
    5. Zhou F, Reineke LC, Khincha PP, Giri N, Mirabello L, Lemon LD, Elghetany MT, Lloyd RE, Alter BP, Savage SA, Bhar S, Morris DK, Bergstrom K, Williams CL, Toh Y, Bertuch AA. Expansion of germline RPS20 mutation phenotype to include Diamond-Blackfan anemia. Hum Mutat. 2020 11; 41(11):1918-1930. PMID: 32790018; PMCID: PMC7857045.
      Citations: 5     Fields:    Translation:HumansCells
    6. Oikarinen M, Bertolet L, Toniolo A, Oikarinen S, Laiho JE, Pugliese A, Lloyd RE, Hy?ty H. Differential Detection of Encapsidated versus Unencapsidated Enterovirus RNA in Samples Containing Pancreatic Enzymes-Relevance for Diabetes Studies. Viruses. 2020 07 11; 12(7). PMID: 32664501; PMCID: PMC7411921.
      Citations: 2     Fields:    Translation:HumansCells
    7. Vehik K, Lynch KF, Wong MC, Tian X, Ross MC, Gibbs RA, Ajami NJ, Petrosino JF, Rewers M, Toppari J, She JX, Akolkar B, Hagopian WA, Schatz DA, Krischer JP, Lloyd RE, TEDDY Study Group, Ziegler AG, Lernmark A, Hy?ty H. Prospective virome analyses in young children at increased genetic risk for type 1 diabetes. Nat Med. 2019 12; 25(12):1865-1872. PMID: 31792456; PMCID: PMC6898786.
      Citations: 70     Fields:    Translation:HumansCells
    8. Lindfors K, Lin J, Lee HS, Nykter M, Kurppa K, Liu E, Koletzko S, Rewers M, Hagopian W, Toppari J, Akolkar B, Krischer JP, Petrosino JF, Lloyd RE, Agardh D, TEDDY Study Group, Hy?ty H, Ziegler AG. Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study. Gut. 2020 08; 69(8):1416-1422. PMID: 31744911; PMCID: PMC7234892.
      Citations: 28     Fields:    Translation:HumansCells
    9. Liu H, Hu PW, Budhiraja S, Misra A, Couturier J, Lloyd RE, Lewis DE, Kimata JT, Rice AP. PACS1 is an HIV-1 cofactor that functions in Rev-mediated nuclear export of viral RNA. Virology. 2020 01 15; 540:88-96. PMID: 31759187; PMCID: PMC7335006.
      Citations: 3     Fields:    Translation:HumansCells
    10. Dunne JL, Richardson SJ, Atkinson MA, Craig ME, Lloyd RE, Morgan NG, Pugliese A, Dahl-J?rgensen K, Flodstr?m-Tullberg M, Hy?ty H. Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence. Reply to Skog O, Klingel K, Roivainen M et al [letter]. Diabetologia. 2019 06; 62(6):1100-1103. PMID: 31016358.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    11. Dunne JL, Richardson SJ, Atkinson MA, Craig ME, Insel RA, Lloyd RE, Morgan NG, Pugliese A, Dahl-J?rgensen K, Flodstr?m-Tullberg M, Hy?ty H, Lernmark ?. Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes. Diabetologia. 2019 05; 62(5):744-753. PMID: 30675626; PMCID: PMC6450860.
      Citations: 31     Fields:    Translation:HumansCells
    12. Stewart CJ, Ajami NJ, O'Brien JL, Hutchinson DS, Smith DP, Wong MC, Ross MC, Lloyd RE, Doddapaneni H, Metcalf GA, Muzny D, Gibbs RA, Vatanen T, Huttenhower C, Xavier RJ, Rewers M, Hagopian W, Toppari J, She JX, Akolkar B, Hyoty H, Vehik K, Krischer JP, Petrosino JF, Ziegler AG, Lernmark A. Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature. 2018 10; 562(7728):583-588. PMID: 30356187; PMCID: PMC6415775.
      Citations: 435     Fields:    Translation:HumansAnimalsCells
    13. Ajami NJ, Wong MC, Ross MC, Lloyd RE, Petrosino JF. Maximal viral information recovery from sequence data using VirMAP. Nat Commun. 2018 08 10; 9(1):3205. PMID: 30097567; PMCID: PMC6086868.
      Citations: 17     Fields:    Translation:HumansCells
    14. Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM. FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation. Cancer Res. 2018 08 01; 78(15):4229-4240. PMID: 29844125; PMCID: PMC6072612.
      Citations: 9     Fields:    Translation:AnimalsCells
    15. Tsai WC, Reineke LC, Jain A, Jung SY, Lloyd RE. Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1. J Biol Chem. 2017 11 17; 292(46):18886-18896. PMID: 28972166; PMCID: PMC5704473.
      Citations: 35     Fields:    Translation:HumansCells
    16. Reineke LC, Tsai WC, Jain A, Kaelber JT, Jung SY, Lloyd RE. Casein Kinase 2 Is Linked to Stress Granule Dynamics through Phosphorylation of the Stress Granule Nucleating Protein G3BP1. Mol Cell Biol. 2017 02 15; 37(4). PMID: 27920254; PMCID: PMC5288577.
      Citations: 40     Fields:    Translation:HumansCells
    17. Heesom K, Locker N, Emmott E, Sorgeloos F, Caddy SL, Vashist S, Sosnovtsev S, Lloyd R, Goodfellow I. Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors. Mol Cell Proteomics. 2017 04; 16(4 suppl 1):S215-S229. PMID: 28087593; PMCID: PMC5393397.
      Citations: 25     Fields:    Translation:HumansCells
    18. Tsai WC, Gayatri S, Reineke LC, Bedford MT, Lloyd RE, Sbardella G. Arginine Demethylation of G3BP1 Promotes Stress Granule Assembly. J Biol Chem. 2016 Oct 21; 291(43):22671-22685. PMID: 27601476; PMCID: PMC5077203.
      Citations: 77     Fields:    Translation:HumansCells
    19. Lloyd RE, Estes MK. Editorial overview: Viruses and cell metabolism. Curr Opin Virol. 2016 08; 19:vii-viii. PMID: 27619793; PMCID: PMC8883798.
      Citations: 1     Fields:    Translation:HumansCells
    20. Lloyd RE. Enterovirus Control of Translation and RNA Granule Stress Responses. Viruses. 2016 Mar 30; 8(4):93. PMID: 27043612; PMCID: PMC4848588.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    21. Dougherty JD, Tsai WC, Lloyd RE. Multiple Poliovirus Proteins Repress Cytoplasmic RNA Granules. Viruses. 2015 Nov 25; 7(12):6127-40. PMID: 26610553; PMCID: PMC4690851.
      Citations: 26     Fields:    Translation:Cells
    22. Lloyd RE. Nuclear proteins hijacked by mammalian cytoplasmic plus strand RNA viruses. Virology. 2015 May; 479-480:457-74. PMID: 25818028; PMCID: PMC4426963.
      Citations: 34     Fields:    Translation:Cells
    23. Reineke LC, Kedersha N, Langereis MA, van Kuppeveld FJ, Lloyd RE. Stress granules regulate double-stranded RNA-dependent protein kinase activation through a complex containing G3BP1 and Caprin1. mBio. 2015 Mar 17; 6(2):e02486. PMID: 25784705; PMCID: PMC4453520.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    24. Reineke LC, Lloyd RE. The stress granule protein G3BP1 recruits protein kinase R to promote multiple innate immune antiviral responses. J Virol. 2015 Mar; 89(5):2575-89. PMID: 25520508; PMCID: PMC4325707.
      Citations: 82     Fields:    Translation:HumansCells
    25. Tsai WC, Lloyd RE. Cytoplasmic RNA Granules and Viral Infection. Annu Rev Virol. 2014 Nov; 1(1):147-70. PMID: 26958719; PMCID: PMC4867093.
      Citations: 40     Fields:    
    26. Feng Q, Langereis MA, Lork M, Nguyen M, Hato SV, Lanke K, Emdad L, Bhoopathi P, Fisher PB, Lloyd RE, van Kuppeveld FJ. Enterovirus 2Apro targets MDA5 and MAVS in infected cells. J Virol. 2014 Mar; 88(6):3369-78. PMID: 24390337; PMCID: PMC3957915.
      Citations: 116     Fields:    Translation:HumansCells
    27. Dougherty JD, Reineke LC, Lloyd RE. mRNA decapping enzyme 1a (Dcp1a)-induced translational arrest through protein kinase R (PKR) activation requires the N-terminal enabled vasodilator-stimulated protein homology 1 (EVH1) domain. J Biol Chem. 2014 Feb 14; 289(7):3936-49. PMID: 24382890; PMCID: PMC3924262.
      Citations: 12     Fields:    Translation:AnimalsCells
    28. Lloyd RE. Regulation of stress granules and P-bodies during RNA virus infection. Wiley Interdiscip Rev RNA. 2013 May-Jun; 4(3):317-31. PMID: 23554219; PMCID: PMC3652661.
      Citations: 56     Fields:    Translation:Cells
    29. Reineke LC, Lloyd RE. Diversion of stress granules and P-bodies during viral infection. Virology. 2013 Feb 20; 436(2):255-67. PMID: 23290869; PMCID: PMC3611887.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    30. Reineke LC, Dougherty JD, Pierre P, Lloyd RE. Large G3BP-induced granules trigger eIF2a phosphorylation. Mol Biol Cell. 2012 Sep; 23(18):3499-510. PMID: 22833567; PMCID: PMC3442399.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    31. Lloyd RE. How do viruses interact with stress-associated RNA granules? PLoS Pathog. 2012; 8(6):e1002741. PMID: 22761570; PMCID: PMC3386173.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    32. White JP, Lloyd RE. Regulation of stress granules in virus systems. Trends Microbiol. 2012 Apr; 20(4):175-83. PMID: 22405519; PMCID: PMC3322245.
      Citations: 109     Fields:    Translation:Cells
    33. Reineke LC, Lloyd RE. Animal virus schemes for translation dominance. Curr Opin Virol. 2011 Nov; 1(5):363-72. PMID: 22319551; PMCID: PMC3272495.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    34. White JP, Lloyd RE. Poliovirus unlinks TIA1 aggregation and mRNA stress granule formation. J Virol. 2011 Dec; 85(23):12442-54. PMID: 21957303; PMCID: PMC3209409.
      Citations: 36     Fields:    Translation:HumansCells
    35. White JP, Reineke LC, Lloyd RE. Poliovirus switches to an eIF2-independent mode of translation during infection. J Virol. 2011 Sep; 85(17):8884-93. PMID: 21697471; PMCID: PMC3165854.
      Citations: 29     Fields:    Translation:HumansCells
    36. Hoeffer CA, Cowansage KK, Arnold EC, Banko JL, Moerke NJ, Rodriguez R, Schmidt EK, Klosi E, Chorev M, Lloyd RE, Pierre P, Wagner G, LeDoux JE, Klann E. Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation. Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8):3383-8. PMID: 21289279; PMCID: PMC3044415.
      Citations: 56     Fields:    Translation:AnimalsCells
    37. Dougherty JD, White JP, Lloyd RE. Poliovirus-mediated disruption of cytoplasmic processing bodies. J Virol. 2011 Jan; 85(1):64-75. PMID: 20962086; PMCID: PMC3014174.
      Citations: 69     Fields:    Translation:HumansCells
    38. Suo J, Snider SJ, Mills GB, Creighton CJ, Chen AC, Schiff R, Lloyd RE, Chang EC. Int6 regulates both proteasomal degradation and translation initiation and is critical for proper formation of acini by human mammary epithelium. Oncogene. 2011 Feb 10; 30(6):724-36. PMID: 20890303; PMCID: PMC3017639.
      Citations: 14     Fields:    Translation:HumansCells
    39. Bonderoff JM, Lloyd RE. Time-dependent increase in ribosome processivity. Nucleic Acids Res. 2010 Nov; 38(20):7054-67. PMID: 20571082; PMCID: PMC2978347.
      Citations: 13     Fields:    Translation:HumansCells
    40. Pond AC, Herschkowitz JI, Schwertfeger KL, Welm B, Zhang Y, York B, Cardiff RD, Hilsenbeck S, Perou CM, Creighton CJ, Lloyd RE, Rosen JM. Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Res. 2010 Jun 15; 70(12):4868-79. PMID: 20501844; PMCID: PMC3005245.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    41. Bonderoff JM, Larey JL, Lloyd RE. Cleavage of poly(A)-binding protein by poliovirus 3C proteinase inhibits viral internal ribosome entry site-mediated translation. J Virol. 2008 Oct; 82(19):9389-99. PMID: 18632855; PMCID: PMC2546981.
      Citations: 37     Fields:    Translation:HumansCells
    42. de Breyne S, Bonderoff JM, Chumakov KM, Lloyd RE, Hellen CU. Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases. Virology. 2008 Aug 15; 378(1):118-22. PMID: 18572216; PMCID: PMC2580754.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    43. Rivera CI, Lloyd RE. Modulation of enteroviral proteinase cleavage of poly(A)-binding protein (PABP) by conformation and PABP-associated factors. Virology. 2008 May 25; 375(1):59-72. PMID: 18321554; PMCID: PMC2409284.
      Citations: 22     Fields:    Translation:HumansCells
    44. Sherrill KW, Lloyd RE. Translation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt. Mol Cell Biol. 2008 Mar; 28(6):2011-22. PMID: 18195037; PMCID: PMC2268400.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    45. Bonderoff JM, Lloyd RE. CVB translation: lessons from the polioviruses. Curr Top Microbiol Immunol. 2008; 323:123-47. PMID: 18357768.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    46. White JP, Cardenas AM, Marissen WE, Lloyd RE. Inhibition of cytoplasmic mRNA stress granule formation by a viral proteinase. Cell Host Microbe. 2007 Nov 15; 2(5):295-305. PMID: 18005751.
      Citations: 201     Fields:    Translation:HumansAnimalsCells
    47. Lloyd RE. Translational control by viral proteinases. Virus Res. 2006 Jul; 119(1):76-88. PMID: 16303201; PMCID: PMC7173276.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    48. Byrd MP, Zamora M, Lloyd RE. Translation of eukaryotic translation initiation factor 4GI (eIF4GI) proceeds from multiple mRNAs containing a novel cap-dependent internal ribosome entry site (IRES) that is active during poliovirus infection. J Biol Chem. 2005 May 13; 280(19):18610-22. PMID: 15755734.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    49. Kuyumcu-Martinez M, Sosnovtsev SV, Chang KO, Green KY, Lloyd RE, Belliot G. Calicivirus 3C-like proteinase inhibits cellular translation by cleavage of poly(A)-binding protein. J Virol. 2004 Aug; 78(15):8172-82. PMID: 15254188; PMCID: PMC446144.
      Citations: 64     Fields:    Translation:HumansCells
    50. Graham KL, Gustin KE, Rivera C, Kuyumcu-Martinez NM, Choe SS, Lloyd RE, Sarnow P, Utz PJ. Proteolytic cleavage of the catalytic subunit of DNA-dependent protein kinase during poliovirus infection. J Virol. 2004 Jun; 78(12):6313-21. PMID: 15163725; PMCID: PMC416498.
      Citations: 10     Fields:    Translation:HumansCells
    51. Sherrill KW, Byrd MP, Van Eden ME, Lloyd RE. BCL-2 translation is mediated via internal ribosome entry during cell stress. J Biol Chem. 2004 Jul 09; 279(28):29066-74. PMID: 15123638.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    52. Van Eden ME, Byrd MP, Sherrill KW, Lloyd RE. Demonstrating internal ribosome entry sites in eukaryotic mRNAs using stringent RNA test procedures. RNA. 2004 Apr; 10(4):720-30. PMID: 15037781; PMCID: PMC1370562.
      Citations: 82     Fields:    Translation:Cells
    53. Van Eden ME, Byrd MP, Sherrill KW, Lloyd RE. Translation of cellular inhibitor of apoptosis protein 1 (c-IAP1) mRNA is IRES mediated and regulated during cell stress. RNA. 2004 Mar; 10(3):469-81. PMID: 14970392; PMCID: PMC1370942.
      Citations: 33     Fields:    Translation:HumansCells
    54. Kuyumcu-Martinez NM, Van Eden ME, Younan P, Lloyd RE. Cleavage of poly(A)-binding protein by poliovirus 3C protease inhibits host cell translation: a novel mechanism for host translation shutoff. Mol Cell Biol. 2004 Feb; 24(4):1779-90. PMID: 14749392; PMCID: PMC344173.
      Citations: 106     Fields:    Translation:HumansCells
    55. Marissen WE, Triyoso D, Younan P, Lloyd RE. Degradation of poly(A)-binding protein in apoptotic cells and linkage to translation regulation. Apoptosis. 2004 Jan; 9(1):67-75. PMID: 14739600.
      Citations: 12     Fields:    Translation:HumansCells
    56. Kuyumcu-Martinez NM, Joachims M, Lloyd RE. Efficient cleavage of ribosome-associated poly(A)-binding protein by enterovirus 3C protease. J Virol. 2002 Mar; 76(5):2062-74. PMID: 11836384; PMCID: PMC135927.
      Citations: 76     Fields:    Translation:HumansCells
    57. Zamora M, Marissen WE, Lloyd RE. Multiple eIF4GI-specific protease activities present in uninfected and poliovirus-infected cells. J Virol. 2002 Jan; 76(1):165-77. PMID: 11739682; PMCID: PMC135685.
      Citations: 24     Fields:    Translation:HumansCells
    58. Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M, Gehrke L, Goldman E, Groner Y, Harford JB, Hatzglou M, He B, Hellen CU, Hentze MW, Hershey J, Hershey P, Hohn T, Holcik M, Hunter CP, Igarashi K, Jackson R, Jagus R, Jefferson LS, Joshi B, Kaempfer R, Katze M, Kaufman RJ, Kiledjian M, Kimball SR, Kimchi A, Kirkegaard K, Koromilas AE, Krug RM, Kruys V, Lamphear BJ, Lemon S, Lloyd RE, Maquat LE, Martinez-Salas E, Mathews MB, Mauro VP, Miyamoto S, Mohr I, Morris DR, Moss EG, Nakashima N, Palmenberg A, Parkin NT, Pe'ery T, Pelletier J, Peltz S, Pestova TV, Pilipenko EV, Prats AC, Racaniello V, Read GS, Rhoads RE, Richter JD, Rivera-Pomar R, Rouault T, Sachs A, Sarnow P, Scheper GC, Schiff L, Schoenberg DR, Semler BL, Siddiqui A, Skern T, Sonenberg N, Sossin W, Standart N, Tahara SM, Thomas AA, Wilusz J, Wimmer E, Witherell G, Wormington M, Donz? O, Toulm? JJ. New ways of initiating translation in eukaryotes. Mol Cell Biol. 2001 Dec; 21(23):8238-46. PMID: 11710333; PMCID: PMC99989.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    59. Marissen WE, Gradi A, Sonenberg N, Lloyd RE. Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis. Cell Death Differ. 2000 Dec; 7(12):1234-43. PMID: 11175261.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    60. Bushell M, Poncet D, Marissen WE, Flotow H, Lloyd RE, Clemens MJ, Morley SJ. Cleavage of polypeptide chain initiation factor eIF4GI during apoptosis in lymphoma cells: characterisation of an internal fragment generated by caspase-3-mediated cleavage. Cell Death Differ. 2000 Jul; 7(7):628-36. PMID: 10889507.
      Citations: 30     Fields:    Translation:HumansCells
    61. Marissen WE, Guo Y, Thomas AA, Matts RL, Lloyd RE. Identification of caspase 3-mediated cleavage and functional alteration of eukaryotic initiation factor 2alpha in apoptosis. J Biol Chem. 2000 Mar 31; 275(13):9314-23. PMID: 10734073.
      Citations: 23     Fields:    Translation:HumansCells
    62. Joachims M, Van Breugel PC, Lloyd RE. Cleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro. J Virol. 1999 Jan; 73(1):718-27. PMID: 9847378; PMCID: PMC103879.
      Citations: 130     Fields:    Translation:HumansCells
    63. Marissen WE, Lloyd RE. Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells. Mol Cell Biol. 1998 Dec; 18(12):7565-74. PMID: 9819442; PMCID: PMC109337.
      Citations: 72     Fields:    Translation:HumansCells
    64. Bovee ML, Lamphear BJ, Rhoads RE, Lloyd RE. Direct cleavage of elF4G by poliovirus 2A protease is inefficient in vitro. Virology. 1998 Jun 05; 245(2):241-9. PMID: 9636363.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    65. Bovee ML, Marissen WE, Zamora M, Lloyd RE. The predominant elF4G-specific cleavage activity in poliovirus-infected HeLa cells is distinct from 2A protease. Virology. 1998 Jun 05; 245(2):229-40. PMID: 9636362.
      Citations: 19     Fields:    Translation:HumansCells
    66. Benton PA, Barrett DJ, Matts RL, Lloyd RE. The outcome of poliovirus infections in K562 cells is cytolytic rather than persistent after hemin-induced differentiation. J Virol. 1996 Aug; 70(8):5525-32. PMID: 8764065; PMCID: PMC190511.
      Citations: 2     Fields:    Translation:HumansCells
    67. Benton PA, Murphy JW, Lloyd RE. K562 cell strains differ in their response to poliovirus infection. Virology. 1995 Oct 20; 213(1):7-18. PMID: 7483280.
      Citations: 6     Fields:    Translation:HumansCells
    68. Yu SF, Benton P, Bovee M, Sessions J, Lloyd RE. Defective RNA replication by poliovirus mutants deficient in 2A protease cleavage activity. J Virol. 1995 Jan; 69(1):247-52. PMID: 7983716; PMCID: PMC188570.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    69. Lloyd RE, Bovee M. Persistent infection of human erythroblastoid cells by poliovirus. Virology. 1993 May; 194(1):200-9. PMID: 8386873.
      Citations: 21     Fields:    Translation:HumansCells
    70. Wyckoff EE, Lloyd RE, Ehrenfeld E. Relationship of eukaryotic initiation factor 3 to poliovirus-induced p220 cleavage activity. J Virol. 1992 May; 66(5):2943-51. PMID: 1313911; PMCID: PMC241053.
      Citations: 21     Fields:    Translation:HumansCells
    71. Yu SF, Lloyd RE. Characterization of the roles of conserved cysteine and histidine residues in poliovirus 2A protease. Virology. 1992 Feb; 186(2):725-35. PMID: 1310193.
      Citations: 27     Fields:    Translation:Cells
    72. Yu SF, Lloyd RE. Identification of essential amino acid residues in the functional activity of poliovirus 2A protease. Virology. 1991 Jun; 182(2):615-25. PMID: 1850921.
      Citations: 42     Fields:    Translation:Cells
    73. Lloyd RE, Grubman MJ, Ehrenfeld E. Relationship of p220 cleavage during picornavirus infection to 2A proteinase sequencing. J Virol. 1988 Nov; 62(11):4216-23. PMID: 2845133; PMCID: PMC253854.
      Citations: 66     Fields:    Translation:HumansCells
    74. Devaney MA, Vakharia VN, Lloyd RE, Ehrenfeld E, Grubman MJ. Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex. J Virol. 1988 Nov; 62(11):4407-9. PMID: 2845152; PMCID: PMC253884.
      Citations: 129     Fields:    Translation:Cells
    75. Lloyd RE, Jense HG, Ehrenfeld E. Restriction of translation of capped mRNA in vitro as a model for poliovirus-induced inhibition of host cell protein synthesis: relationship to p220 cleavage. J Virol. 1987 Aug; 61(8):2480-8. PMID: 3037110; PMCID: PMC255675.
      Citations: 28     Fields:    Translation:AnimalsCells
    76. Lloyd RE, Toyoda H, Etchison D, Wimmer E, Ehrenfeld E. Cleavage of the cap binding protein complex polypeptide p220 is not effected by the second poliovirus protease 2A. Virology. 1986 Apr 15; 150(1):299-303. PMID: 3006342.
      Citations: 35     Fields:    Translation:HumansCells
    77. Lloyd RE, Etchison D, Ehrenfeld E. Poliovirus protease does not mediate cleavage of the 220,000-Da component of the cap binding protein complex. Proc Natl Acad Sci U S A. 1985 May; 82(9):2723-7. PMID: 2986132; PMCID: PMC397637.
      Citations: 17     Fields:    Translation:HumansCells
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