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David L. Nelson

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Human Genetics
DivisionMolecular & Human Genetics
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentHuman Genome Sequencing Center
    DivisionHuman Genome Sequencing Center


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    R01HD006571     (NELSON, DAVID L)May 1, 1978 - Apr 30, 1996
    NIH/NICHD
    HORMONAL CONTROL OF METABOLISM IN THE MAMMARY GLAND
    Role: Principal Investigator

    R01GM032514     (NELSON, DAVID LOREN)Jul 1, 1983 - Mar 31, 1994
    NIH/NIGMS
    ANTIBODIES TO DISSECT SENSORY TRANSDUCTION IN PARAMECIUM
    Role: Principal Investigator

    R01GM034906     (NELSON, DAVID L)Jul 1, 1983 - Mar 31, 2002
    NIH/NIGMS
    MOTILE RESPONSE TO PURINOCEPTOR IN PARAMECIUM
    Role: Principal Investigator

    R03AR036986     (NELSON, DAVID LOREN)Sep 22, 1986 - Sep 21, 1988
    NIH/NIAMS
    INTERMITTENT PASSIVE MOTION IN FLEXOR TENDON INJURIES
    Role: Principal Investigator

    T32GM008231     (NELSON, DAVID LOREN)Jul 1, 1990 - Jun 30, 2020
    NIH/NIGMS
    Training Program in Cell and Molecular Biology
    Role: Principal Investigator

    P30HG000210     (NELSON, DAVID LOREN)Feb 1, 1991 - Jan 31, 1997
    NIH/NHGRI
    BCM HUMAN GENOME PROGRAM
    Role: Principal Investigator

    F36GM013958     (NELSON, DAVID LOREN)Sep 1, 1991 - Aug 30, 1991
    NIH/NIGMS
    MARC VISITING SCIENTIST AT SPELMAN COLLEGE
    Role: Principal Investigator

    R01HD029256     (NELSON, DAVID LOREN)Apr 1, 1992 - Mar 31, 2004
    NIH/NICHD
    MOLECULAR ANALYSIS OF FRAGILE X SYNDROME
    Role: Principal Investigator

    R01HG000973     (NELSON, DAVID LOREN)Dec 10, 1993 - Nov 30, 1997
    NIH/NHGRI
    NEW ANALYSIS TOOLS FOR GENE FUNCTION IDENTIFICATION
    Role: Principal Investigator

    R13HG001569     (NELSON, DAVID LOREN)Sep 30, 1996 - Sep 29, 1997
    NIH/NHGRI
    X CHROMOSOME SEQUENCING WORKSHOP
    Role: Principal Investigator

    R01HD035617     (NELSON, DAVID LOREN)Aug 1, 1997 - Nov 30, 2008
    NIH/NICHD
    Molecular Analysis of Xq28-Linked Incontinentia Pigmenti
    Role: Principal Investigator

    R01CA075432     (NELSON, DAVID LOREN)Sep 22, 1997 - Mar 31, 2007
    NIH/NCI
    Sequence and Haplotypes for Analysis of Cancer Genes
    Role: Principal Investigator

    R01HD038038     (NELSON, DAVID LOREN)Aug 10, 1999 - May 31, 2011
    NIH/NICHD
    Fragile X Related Genes Mental Retardation/Development
    Role: Principal Investigator

    R24CA082924     (NELSON, DAVID LOREN)Sep 7, 1999 - Jun 30, 2004
    NIH/NCI
    BAYLOR COLLEGE OF MEDICINE MICROARRY FACILITY FOR NCI FU
    Role: Principal Investigator

    R01NS051630     (JIN, PENG)Apr 1, 2005 - Jan 31, 2024
    NIH/NINDS
    Molecular Basis of rCGG-Mediated Neurodegeneration
    Role: Co-Principal Investigator

    U54HD083092     (ZOGHBI, HUDA Y)Sep 23, 2014 - May 31, 2020
    NIH/NICHD
    Baylor Intellectual and Developmental Disabilities Research Centers
    Role: Co-Principal Investigator

    R21HD084802     (NELSON, DAVID LOREN)Apr 1, 2016 - Mar 31, 2018
    NIH/NICHD
    Improved mouse models to study Fragile X associated primary ovarian insufficiency
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gravesteijn B, Sewalt C, Ercole A, Akerlund C, Nelson D, Maas A, Menon D, Lingsma HF, Steyerberg EW. Towards a new multidimensional classification of traumatic brain injury: a CENTER-TBI study. J Neurotrauma. 2019 Nov 01. PMID: 31672086.
      View in: PubMed
    2. Porcino GN, Antinarelli LMR, Maia ACRG, Faria-Pinto P, Taunay-Rodrigues A, Zech Coelho PM, Nelson DL, Penido MLO, Coimbra ES, Vasconcelos EG. The alkylaminoalkanethiosulfuric acids exhibit in-vitro antileishmanial activity against Leishmania (Viannia) braziliensis: a new perspective for use of these schistosomicidal agents. J Pharm Pharmacol. 2019 Dec; 71(12):1784-1791. PMID: 31579947.
      View in: PubMed
    3. Steyerberg EW, Wiegers E, Sewalt C, Buki A, Citerio G, De Keyser V, Ercole A, Kunzmann K, Lanyon L, Lecky F, Lingsma H, Manley G, Nelson D, Peul W, Stocchetti N, von Steinbüchel N, Vande Vyvere T, Verheyden J, Wilson L, Maas AIR, Menon DK. Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study. Lancet Neurol. 2019 Oct; 18(10):923-934. PMID: 31526754.
      View in: PubMed
    4. Lovelace JW, Rais M, Palacios AR, Shuai XS, Bishay S, Popa O, Pirbhoy PS, Binder DK, Nelson DL, Ethell IM, Razak KA. Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome. Cereb Cortex. 2019 Jul 29. PMID: 31364704.
      View in: PubMed
    5. Walkley SU, Abbeduto L, Batshaw ML, Bhattacharyya A, Bookheimer SY, Christian BT, Constantino JN, de Vellis J, Doherty DA, Nelson DL, Piven J, Poduri A, Pomeroy SL, Samaco RC, Zoghbi HY, Guralnick MJ. Intellectual and developmental disabilities research centers: Fifty years of scientific accomplishments. Ann Neurol. 2019 Sep; 86(3):332-343. PMID: 31206741.
      View in: PubMed
    6. Barbosa SL, Ottone M, Freitas MS, Lima CD, Nelson DL, Clososki GC, Caires FJ, Klein SI, Hurtado GR. Synthesis of Phenyl Esters Using SiO2-SO3H Catalyst in Conventional Heating and Microwave-Irradiated Esterification Processes. J Nanosci Nanotechnol. 2019 Jun 01; 19(6):3663-3668. PMID: 30744803.
      View in: PubMed
    7. Kong HE, Lim J, Zhang F, Huang L, Gu Y, Nelson DL, Allen EG, Jin P. Metabolic pathways modulate the neuronal toxicity associated with fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2019 03 15; 28(6):980-991. PMID: 30476102.
      View in: PubMed
    8. Graham DL, Beio ML, Nelson DL, Berkowitz DB. Human Serine Racemase: Key Residues/Active Site Motifs and Their Relation to Enzyme Function. Front Mol Biosci. 2019; 6:8. PMID: 30918891.
      View in: PubMed
    9. Nelson DL. 2018 Presidential Address: Who Are We? Am J Hum Genet. 2019 Mar 07; 104(3):363-372. PMID: 30849321.
      View in: PubMed
    10. Estañ MC, Fernández-Núñez E, Zaki MS, Esteban MI, Donkervoort S, Hawkins C, Caparros-Martin JA, Saade D, Hu Y, Bolduc V, Chao KR, Nevado J, Lamuedra A, Largo R, Herrero-Beaumont G, Regadera J, Hernandez-Chico C, Tizzano EF, Martinez-Glez V, Carvajal JJ, Zong R, Nelson DL, Otaify GA, Temtamy S, Aglan M, Issa M, Bönnemann CG, Lapunzina P, Yoon G, Ruiz-Perez VL. Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy. Nat Commun. 2019 02 15; 10(1):797. PMID: 30770808.
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    11. Volovici V, Ercole A, Citerio G, Stocchetti N, Haitsma IK, Huijben JA, Dirven CMF, van der Jagt M, Steyerberg EW, Nelson D, Cnossen MC, Maas AIR, Polinder S, Menon DK, Lingsma HF. Variation in Guideline Implementation and Adherence Regarding Severe Traumatic Brain Injury Treatment: A CENTER-TBI Survey Study in Europe. World Neurosurg. 2019 May; 125:e515-e520. PMID: 30710717.
      View in: PubMed
    12. Saha S, Hosmani PS, Villalobos-Ayala K, Miller S, Shippy T, Flores M, Rosendale A, Cordola C, Bell T, Mann H, DeAvila G, DeAvila D, Moore Z, Buller K, Ciolkevich K, Nandyal S, Mahoney R, Voorhis JV, Dunlevy M, Farrow D, Hunter D, Morgan T, Shore K, Guzman V, Izsak A, Dixon DE, Cridge A, Cano L, Cao X, Jiang H, Leng N, Johnson S, Cantarel BL, Richards S, English A, Shatters RG, Childers C, Chen MJ, Hunter W, Cilia M, Mueller LA, Munoz-Torres M, Nelson D, Poelchau MF, Benoit JB, Wiersma-Koch H, D'Elia T, Brown SJ. Improved annotation of the insect vector of citrus greening disease: biocuration by a diverse genomics community. Database (Oxford). 2019 01 01; 2019. PMID: 30820572.
      View in: PubMed
    13. Teixeira ML, Marcussi S, de C S Rezende DA, Magalhães ML, Nelson DL, das G Cardoso M. Essential Oil from Lippia origanoides (Verbenaceae): Haemostasis and Enzymes Activity Alterations. Med Chem. 2019; 15(2):207-214. PMID: 30160215.
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    14. Bohm M, Shin A, Teagarden S, Xu H, Gupta A, Siwiec R, Nelson D, Wo JM. Risk Factors Associated With Upper Aerodigestive Tract or Coliform Bacterial Overgrowth of the Small Intestine in Symptomatic Patients. J Clin Gastroenterol. 2018 Dec 19. PMID: 30575635.
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    15. Wolfe AR, Neitz RJ, Burlingame M, Suzuki BM, Lim KC, Scheideler M, Nelson DL, Benet LZ, Caffrey CR. TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling. Int J Parasitol Drugs Drug Resist. 2018 12; 8(3):571-586. PMID: 30503203.
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    16. Volovici V, Ercole A, Citerio G, Stocchetti N, Haitsma IK, Huijben JA, Dirven CMF, van der Jagt M, Steyerberg EW, Nelson D, Cnossen MC, Maas AIR, Polinder S, Menon DK, Lingsma HF. Intensive care admission criteria for traumatic brain injury patients across Europe. J Crit Care. 2019 Feb; 49:158-161. PMID: 30447560.
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    17. Barcelos MCS, Lupki FB, Campolina GA, Nelson DL, Molina G. The colors of biotechnology: general overview and developments of white, green and blue areas. FEMS Microbiol Lett. 2018 11 01; 365(21). PMID: 30256942.
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    18. Campoccia Jalde F, Jalde F, Wallin MKEB, Suarez-Sipmann F, Radell PJ, Nelson D, Eksborg S, Sackey PV. Standardized Unloading of Respiratory Muscles during Neurally Adjusted Ventilatory Assist: A Randomized Crossover Pilot Study. Anesthesiology. 2018 10; 129(4):769-777. PMID: 30045094.
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    19. Valinhas RV, Pantoja LA, Maia ACF, Miguel MGCP, Vanzela APFC, Nelson DL, Santos AS. Xylose fermentation to ethanol by new Galactomyces geotrichum and Candida akabanensis strains. PeerJ. 2018; 6:e4673. PMID: 29719736.
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    20. Barbosa SL, Lima CD, Almeida MAR, Mourão LS, Ottone M, Nelson DL, Klein SI, Zanatta LD, Clososki GC, Caires FJ, Nassar EJ, Hurtado GR. The preparation of benzyl esters using stoichiometric niobium (V) chloride versus niobium grafted SiO2 catalyst: A comparison study. Heliyon. 2018 Mar; 4(3):e00571. PMID: 29862338.
      View in: PubMed
    21. Nelson DL. Turning the corner from observation to intervention in human genetics. J Genet Genomics. 2018 02 20; 45(2):57-59. PMID: 29477468.
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    22. Wei C, Stock L, Valanejad L, Zalewski ZA, Karns R, Puymirat J, Nelson D, Witte D, Woodgett J, Timchenko NA, Timchenko L. Correction of GSK3ß at young age prevents muscle pathology in mice with myotonic dystrophy type 1. FASEB J. 2018 04; 32(4):2073-2085. PMID: 29203592.
      View in: PubMed
    23. de Andrade Santiago J, Cardoso MDG, Batista LR, Santiago WD, Passamani FRF, Rodrigues LMA, Nelson DL. Effect of the essential oils from Melaleuca alternifolia, Melaleuca quinquenervia and Backhousia citriodora on the synthesis of ochratoxin A by Aspergillus niger and Aspergillus carbonarius isolated from tropical wine grapes. J Food Sci Technol. 2018 Jan; 55(1):418-423. PMID: 29358835.
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    24. Cnossen MC, Huijben JA, van der Jagt M, Volovici V, van Essen T, Polinder S, Nelson D, Ercole A, Stocchetti N, Citerio G, Peul WC, Maas AIR, Menon D, Steyerberg EW, Lingsma HF. Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study. Crit Care. 2017 Sep 06; 21(1):233. PMID: 28874206.
      View in: PubMed
    25. Nelson DL, Applegate GA, Beio ML, Graham DL, Berkowitz DB. Human serine racemase structure/activity relationship studies provide mechanistic insight and point to position 84 as a hot spot for ß-elimination function. J Biol Chem. 2017 08 25; 292(34):13986-14002. PMID: 28696262.
      View in: PubMed
    26. Valanejad L, Lewis K, Wright M, Jiang Y, D'Souza A, Karns R, Sheridan R, Gupta A, Bove K, Witte D, Geller J, Tiao G, Nelson DL, Timchenko L, Timchenko N. FXR-Gankyrin axis is involved in development of pediatric liver cancer. Carcinogenesis. 2017 07 01; 38(7):738-747. PMID: 28535186.
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    27. Rodriguez MM, Overshiner C, Leander JD, Li X, Morrow D, Conway RG, Nelson DL, Briner K, Witkin JM. Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive-Compulsive Disorder. Front Psychiatry. 2017; 8:89. PMID: 28588509.
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    28. Nelson DL. 2016 William Allan Award Introduction: James Gusella. Am J Hum Genet. 2017 Mar 02; 100(3):385-386. PMID: 28257684.
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    29. Saha S, Hosmani PS, Villalobos-Ayala K, Miller S, Shippy T, Flores M, Rosendale A, Cordola C, Bell T, Mann H, DeAvila G, DeAvila D, Moore Z, Buller K, Ciolkevich K, Nandyal S, Mahoney R, Van Voorhis J, Dunlevy M, Farrow D, Hunter D, Morgan T, Shore K, Guzman V, Izsak A, Dixon DE, Cridge A, Cano L, Cao X, Jiang H, Leng N, Johnson S, Cantarel BL, Richards S, English A, Shatters RG, Childers C, Chen MJ, Hunter W, Cilia M, Mueller LA, Munoz-Torres M, Nelson D, Poelchau MF, Benoit JB, Wiersma-Koch H, D'Elia T, Brown SJ. Improved annotation of the insect vector of citrus greening disease: biocuration by a diverse genomics community. Database (Oxford). 2017 01 01; 2017. PMID: 29220441.
      View in: PubMed
    30. Svensson KA, Heinz BA, Schaus JM, Beck JP, Hao J, Krushinski JH, Reinhard MR, Cohen MP, Hellman SL, Getman BG, Wang X, Menezes MM, Maren DL, Falcone JF, Anderson WH, Wright RA, Morin SM, Knopp KL, Adams BL, Rogovoy B, Okun I, Suter TM, Statnick MA, Gehlert DR, Nelson DL, Lucaites VL, Emkey R, DeLapp NW, Wiernicki TR, Cramer JW, Yang CR, Bruns RF. An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis. J Pharmacol Exp Ther. 2017 Jan; 360(1):117-128. PMID: 27811173.
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    31. Caggiano NM, Nelson DL, Kaplan SJ, Matullo KS. Wrong-Bone Excision in Hand Surgery. Hand (N Y). 2017 09; 12(5):467-470. PMID: 28832204.
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    32. Battaglia C, Farmer MM, Widome R, Hagedorn H, Roth TDC, Nelson D, Zillich AJ, Fu SS. Evaluation of a Motivational Interviewing Training Program for Tobacco Cessation Counseling in Primary Care. Fed Pract. 2016 Aug; 33(8):12-17. PMID: 30766193.
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    33. Higashimori H, Schin CS, Chiang MS, Morel L, Shoneye TA, Nelson DL, Yang Y. Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo. J Neurosci. 2016 07 06; 36(27):7079-94. PMID: 27383586.
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    34. Xu H, Song J, Luo H, Zhang Y, Li Q, Zhu Y, Xu J, Li Y, Song C, Wang B, Sun W, Shen G, Zhang X, Qian J, Ji A, Xu Z, Luo X, He L, Li C, Sun C, Yan H, Cui G, Li X, Li X, Wei J, Liu J, Wang Y, Hayward A, Nelson D, Ning Z, Peters RJ, Qi X, Chen S. Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza. Mol Plant. 2016 06 06; 9(6):949-52. PMID: 27018390.
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    35. Fu SS, van Ryn M, Nelson D, Burgess DJ, Thomas JL, Saul J, Clothier B, Nyman JA, Hammett P, Joseph AM. Proactive tobacco treatment offering free nicotine replacement therapy and telephone counselling for socioeconomically disadvantaged smokers: a randomised clinical trial. Thorax. 2016 May; 71(5):446-53. PMID: 26931362.
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    36. Zhang D, Blanco MJ, Ying BP, Kohlman D, Liang SX, Victor F, Chen Q, Krushinski J, Filla SA, Hudziak KJ, Mathes BM, Cohen MP, Zacherl D, Nelson DL, Wainscott DB, Nutter SE, Gough WH, Schaus JM, Xu YC. Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT1 F receptor agonists: Evolution from bicyclic to monocyclic cores. Bioorg Med Chem Lett. 2015 Oct 01; 25(19):4337-41. PMID: 26271587.
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    37. Nam D, Guo B, Chatterjee S, Chen MH, Nelson D, Yechoor VK, Ma K. The adipocyte clock controls brown adipogenesis through the TGF-ß and BMP signaling pathways. J Cell Sci. 2015 May 01; 128(9):1835-47. PMID: 25749863.
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    38. Braat S, D'Hulst C, Heulens I, De Rubeis S, Mientjes E, Nelson DL, Willemsen R, Bagni C, Van Dam D, De Deyn PP, Kooy RF. The GABAA receptor is an FMRP target with therapeutic potential in fragile X syndrome. Cell Cycle. 2015; 14(18):2985-95. PMID: 25790165.
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    39. Lumaban JG, Nelson DL. The Fragile X proteins Fmrp and Fxr2p cooperate to regulate glucose metabolism in mice. Hum Mol Genet. 2015 Apr 15; 24(8):2175-84. PMID: 25552647.
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    40. Cook D, Nuro E, Jones EV, Altimimi HF, Farmer WT, Gandin V, Hanna E, Zong R, Barbon A, Nelson DL, Topisirovic I, Rochford J, Stellwagen D, Béïque JC, Murai KK. FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation. Cell Rep. 2014 Nov 20; 9(4):1402-1416. PMID: 25456134.
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    41. Mullegama SV, Pugliesi L, Burns B, Shah Z, Tahir R, Gu Y, Nelson DL, Elsea SH. MBD5 haploinsufficiency is associated with sleep disturbance and disrupts circadian pathways common to Smith-Magenis and fragile X syndromes. Eur J Hum Genet. 2015 Jun; 23(6):781-9. PMID: 25271084.
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    42. Berman RF, Buijsen RA, Usdin K, Pintado E, Kooy F, Pretto D, Pessah IN, Nelson DL, Zalewski Z, Charlet-Bergeurand N, Willemsen R, Hukema RK. Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome. J Neurodev Disord. 2014; 6(1):25. PMID: 25136376.
      View in: PubMed
    43. Galloway JN, Shaw C, Yu P, Parghi D, Poidevin M, Jin P, Nelson DL. CGG repeats in RNA modulate expression of TDP-43 in mouse and fly models of fragile X tremor ataxia syndrome. Hum Mol Genet. 2014 Nov 15; 23(22):5906-15. PMID: 24986919.
      View in: PubMed
    44. Yao B, Lin L, Street RC, Zalewski ZA, Galloway JN, Wu H, Nelson DL, Jin P. Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome. Hum Mol Genet. 2014 Feb 15; 23(4):1095-107. PMID: 24108107.
      View in: PubMed
    45. Liesching T, Nelson DL, Cormier KL, Sucov A, Short K, Warburton R, Hill NS. Randomized trial of bilevel versus continuous positive airway pressure for acute pulmonary edema. J Emerg Med. 2014 Jan; 46(1):130-40. PMID: 24071031.
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    46. de R Machado AM, Cardoso Md, Dórea HS, Emídio ES, Silva MM, dos Anjos JP, Saczk AA, Nelson DL. Contamination of cachaça by PAHs from storage containers. Food Chem. 2014 Mar 01; 146:65-70. PMID: 24176314.
      View in: PubMed
    47. Cao M, Prima V, Nelson D, Svetlov S. Composite fatty acid ether amides suppress growth of liver cancer cells in vitro and in an in vivo allograft mouse model. Cell Oncol (Dordr). 2013 Jun; 36(3):247-57. PMID: 23619943.
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    48. Vislay RL, Martin BS, Olmos-Serrano JL, Kratovac S, Nelson DL, Corbin JG, Huntsman MM. Homeostatic responses fail to correct defective amygdala inhibitory circuit maturation in fragile X syndrome. J Neurosci. 2013 Apr 24; 33(17):7548-58. PMID: 23616559.
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    49. Xu Z, Poidevin M, Li X, Li Y, Shu L, Nelson DL, Li H, Hales CM, Gearing M, Wingo TS, Jin P. Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration. Proc Natl Acad Sci U S A. 2013 May 07; 110(19):7778-83. PMID: 23553836.
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    50. Lee J, Moulik M, Fang Z, Saha P, Zou F, Xu Y, Nelson DL, Ma K, Moore DD, Yechoor VK. Bmal1 and ß-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced ß-cell failure in mice. Mol Cell Biol. 2013 Jun; 33(11):2327-38. PMID: 23547261.
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    51. Nelson DL, Orr HT, Warren ST. The unstable repeats--three evolving faces of neurological disease. Neuron. 2013 Mar 06; 77(5):825-43. PMID: 23473314.
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    52. de Resende Machado AM, Cardoso Md, Saczk AA, dos Anjos JP, Zacaroni LM, Dórea HS, Nelson DL. Determination of ethyl carbamate in cachaça produced from copper stills by HPLC. Food Chem. 2013 Jun 01; 138(2-3):1233-8. PMID: 23411237.
      View in: PubMed
    53. Nagamani SC, Erez A, Probst FJ, Bader P, Evans P, Baker LA, Fang P, Bertin T, Hixson P, Stankiewicz P, Nelson D, Patel A, Cheung SW. Small genomic rearrangements involving FMR1 support the importance of its gene dosage for normal neurocognitive function. Neurogenetics. 2012 Nov; 13(4):333-9. PMID: 22890812.
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    54. Panigrahi K, Nelson DL, Berkowitz DB. Unleashing a "true" pSer-mimic in the cell. Chem Biol. 2012 Jun 22; 19(6):666-7. PMID: 22726679.
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    55. Fell MJ, Katner JS, Rasmussen K, Nikolayev A, Kuo MS, Nelson DL, Perry KW, Svensson KA. Typical and atypical antipsychotic drugs increase extracellular histamine levels in the rat medial prefrontal cortex: contribution of histamine h(1) receptor blockade. Front Psychiatry. 2012; 3:49. PMID: 22629251.
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    56. Yrigollen CM, Durbin-Johnson B, Gane L, Nelson DL, Hagerman R, Hagerman PJ, Tassone F. AGG interruptions within the maternal FMR1 gene reduce the risk of offspring with fragile X syndrome. Genet Med. 2012 Aug; 14(8):729-36. PMID: 22498846.
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    57. Qurashi A, Liu H, Ray L, Nelson DL, Duan R, Jin P. Chemical screen reveals small molecules suppressing fragile X premutation rCGG repeat-mediated neurodegeneration in Drosophila. Hum Mol Genet. 2012 May 01; 21(9):2068-75. PMID: 22298836.
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    58. Xu XL, Zong R, Li Z, Biswas MH, Fang Z, Nelson DL, Gao FB. FXR1P but not FMRP regulates the levels of mammalian brain-specific microRNA-9 and microRNA-124. J Neurosci. 2011 Sep 28; 31(39):13705-9. PMID: 21957233.
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    59. Tan H, Qurashi A, Poidevin M, Nelson DL, Li H, Jin P. Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration. Hum Mol Genet. 2012 Jan 01; 21(1):57-65. PMID: 21940752.
      View in: PubMed
    60. Jain A, Kovacs JA, Nelson DL, Migueles SA, Pittaluga S, Fanslow W, Fan X, Wong DW, Massey J, Hornung R, Brown MR, Spinner JJ, Liu S, Davey V, Hill HA, Ochs H, Fleisher TA. Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand. Blood. 2011 Oct 06; 118(14):3811-7. PMID: 21841160.
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    61. Whitman SA, Cover C, Yu L, Nelson DL, Zarnescu DC, Gregorio CC. Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle. Circ Res. 2011 Jul 22; 109(3):262-71. PMID: 21659647.
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    62. Bauerschmidt B, Nelson DL. The terms occupation and activity over the history of official occupational therapy publications. Am J Occup Ther. 2011 May-Jun; 65(3):338-45. PMID: 21675340.
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    63. Guo W, Allan AM, Zong R, Zhang L, Johnson EB, Schaller EG, Murthy AC, Goggin SL, Eisch AJ, Oostra BA, Nelson DL, Jin P, Zhao X. Ablation of Fmrp in adult neural stem cells disrupts hippocampus-dependent learning. Nat Med. 2011 May; 17(5):559-65. PMID: 21516088.
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    64. Anderson KM, Nelson DL. Wanted: entrepreneurs in occupational therapy. Am J Occup Ther. 2011 Mar-Apr; 65(2):221-8. PMID: 21476371.
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    65. Levenga J, Hayashi S, de Vrij FM, Koekkoek SK, van der Linde HC, Nieuwenhuizen I, Song C, Buijsen RA, Pop AS, Gomezmancilla B, Nelson DL, Willemsen R, Gasparini F, Oostra BA. AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome. Neurobiol Dis. 2011 Jun; 42(3):311-7. PMID: 21316452.
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    66. Clough JF, Hitchcock K, Nelson DL. Using PubMed effectively to access the orthopaedic literature. Instr Course Lect. 2011; 60:607-18. PMID: 21553803.
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    67. Applegate GA, Cheloha RW, Nelson DL, Berkowitz DB. A new dehydrogenase from Clostridium acetobutylicum for asymmetric synthesis: dynamic reductive kinetic resolution entry into the Taxotère side chain. Chem Commun (Camb). 2011 Feb 28; 47(8):2420-2. PMID: 21173953.
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    68. Meyer SE, Nelson DL, Clement S, Ramakrishnan A. Ecological genetics of the Bromus tectorum (Poaceae)-Ustilago bullata (Ustilaginaceae) pathosystem: A role for frequency-dependent selection? Am J Bot. 2010 Aug; 97(8):1304-12. PMID: 21616883.
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    69. Arnt J, Bang-Andersen B, Grayson B, Bymaster FP, Cohen MP, DeLapp NW, Giethlen B, Kreilgaard M, McKinzie DL, Neill JC, Nelson DL, Nielsen SM, Poulsen MN, Schaus JM, Witten LM. Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats. Int J Neuropsychopharmacol. 2010 Sep; 13(8):1021-33. PMID: 20569520.
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    70. Nelson DL, Phebus LA, Johnson KW, Wainscott DB, Cohen ML, Calligaro DO, Xu YC. Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan. Cephalalgia. 2010 Oct; 30(10):1159-69. PMID: 20855361.
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    71. Mehta S, Heffer MJ, Maham N, Nelson DL, Klinger JR, Levy MM. Impact of endotracheal tube size on preextubation respiratory variables. J Crit Care. 2010 Sep; 25(3):483-8. PMID: 20079602.
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    72. Galloway JN, Nelson DL. Evidence for RNA-mediated toxicity in the fragile X-associated tremor/ataxia syndrome. Future Neurol. 2009 Nov 01; 4(6):785. PMID: 20161676.
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    73. Fell MJ, Perry KW, Falcone JF, Johnson BG, Barth VN, Rash KS, Lucaites VL, Threlkeld PG, Monn JA, McKinzie DL, Marek GJ, Svensson KA, Nelson DL. In vitro and in vivo evidence for a lack of interaction with dopamine D2 receptors by the metabotropic glutamate 2/3 receptor agonists 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-bicaroxylate monohydrate (LY354740) and (-)-2-oxa-4-aminobicyclo[3.1.0] Hexane-4,6-dicarboxylic acid (LY379268). J Pharmacol Exp Ther. 2009 Dec; 331(3):1126-36. PMID: 19755662.
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    74. Levenga J, Buijsen RA, Rifé M, Moine H, Nelson DL, Oostra BA, Willemsen R, de Vrij FM. Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons. Neurobiol Dis. 2009 Aug; 35(2):241-50. PMID: 19464371.
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    75. Nelson DL, Gibbs RA. X-cess of variants in XLMR. Nat Genet. 2009 May; 41(5):510-2. PMID: 19399033.
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    76. Hashem V, Galloway JN, Mori M, Willemsen R, Oostra BA, Paylor R, Nelson DL. Ectopic expression of CGG containing mRNA is neurotoxic in mammals. Hum Mol Genet. 2009 Jul 01; 18(13):2443-51. PMID: 19377084.
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    77. Zhang J, Hou L, Klann E, Nelson DL. Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models. J Neurophysiol. 2009 May; 101(5):2572-80. PMID: 19244359.
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    78. Paylor R, Yuva-Paylor LA, Nelson DL, Spencer CM. Reversal of sensorimotor gating abnormalities in Fmr1 knockout mice carrying a human Fmr1 transgene. Behav Neurosci. 2008 Dec; 122(6):1371-7. PMID: 19045956.
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    79. Nakajima M, Yamada M, Yamaguchi K, Sakiyama Y, Oda A, Nelson DL, Yawaka Y, Ariga T. Possible application of flow cytometry for evaluation of the structure and functional status of WASP in peripheral blood mononuclear cells. Eur J Haematol. 2009 Mar; 82(3):223-30. PMID: 19018864.
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    80. de Oliveira Penido ML, Zech Coelho PM, de Mello RT, Piló-Veloso D, de Oliveira MC, Kusel JR, Nelson DL. Antischistosomal activity of aminoalkanethiols, aminoalkanethiosulfuric acids and the corresponding disulfides. Acta Trop. 2008 Nov-Dec; 108(2-3):249-55. PMID: 18996349.
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    81. Sofola O, Sundram V, Ng F, Kleyner Y, Morales J, Botas J, Jackson FR, Nelson DL. The Drosophila FMRP and LARK RNA-binding proteins function together to regulate eye development and circadian behavior. J Neurosci. 2008 Oct 08; 28(41):10200-5. PMID: 18842880.
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    82. Berkowitz DB, Karukurichi KR, de la Salud-Bea R, Nelson DL, McCune CD. Use of Fluorinated Functionality in Enzyme Inhibitor Development: Mechanistic and Analytical Advantages. J Fluor Chem. 2008 Sep; 129(9):731-742. PMID: 19727327.
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    83. Zhang J, Fang Z, Jud C, Vansteensel MJ, Kaasik K, Lee CC, Albrecht U, Tamanini F, Meijer JH, Oostra BA, Nelson DL. Fragile X-related proteins regulate mammalian circadian behavioral rhythms. Am J Hum Genet. 2008 Jul; 83(1):43-52. PMID: 18589395.
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    84. Spencer CM, Graham DF, Yuva-Paylor LA, Nelson DL, Paylor R. Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene. Behav Neurosci. 2008 Jun; 122(3):710-5. PMID: 18513141.
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    85. de Vrij FM, Levenga J, van der Linde HC, Koekkoek SK, De Zeeuw CI, Nelson DL, Oostra BA, Willemsen R. Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice. Neurobiol Dis. 2008 Jul; 31(1):127-32. PMID: 18571098.
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    86. Stewart DM, Tian L, Notarangelo LD, Nelson DL. X-linked hypogammaglobulinemia and isolated growth hormone deficiency: an update. Immunol Res. 2008; 40(3):262-70. PMID: 18180883.
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    87. Kelley DJ, Davidson RJ, Nelson DL. An imaging roadmap for biology education: from nanoparticles to whole organisms. CBE Life Sci Educ. 2008; 7(2):202-9. PMID: 18519611.
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    88. Kelley DJ, Farhoud M, Meyerand ME, Nelson DL, Ramirez LF, Dempsey RJ, Wolf AJ, Alexander AL, Davidson RJ. Creating physical 3D stereolithograph models of brain and skull. PLoS One. 2007 Oct 31; 2(10):e1119. PMID: 17971879.
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    89. Butts DS, Nelson DL. Agreement between Occupational Therapy Practice Framework classifications and occupational therapists' classifications. Am J Occup Ther. 2007 Sep-Oct; 61(5):512-8. PMID: 17944288.
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    90. Krushinski JH, Schaus JM, Thompson DC, Calligaro DO, Nelson DL, Luecke SH, Wainscott DB, Wong DT. Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists. Bioorg Med Chem Lett. 2007 Oct 15; 17(20):5600-4. PMID: 17804228.
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    91. Sofola OA, Jin P, Qin Y, Duan R, Liu H, de Haro M, Nelson DL, Botas J. RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS. Neuron. 2007 Aug 16; 55(4):565-71. PMID: 17698010.
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    92. Stewart DM, Candotti F, Nelson DL. The phenomenon of spontaneous genetic reversions in the Wiskott-Aldrich syndrome: a report of the workshop of the ESID Genetics Working Party at the XIIth Meeting of the European Society for Immunodeficiencies (ESID). Budapest, Hungary October 4-7, 2006. J Clin Immunol. 2007 Nov; 27(6):634-9. PMID: 17690954.
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    93. Sofola OA, Jin P, Botas J, Nelson DL. Argonaute-2-dependent rescue of a Drosophila model of FXTAS by FRAXE premutation repeat. Hum Mol Genet. 2007 Oct 01; 16(19):2326-32. PMID: 17635840.
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    94. Probst FJ, Roeder ER, Enciso VB, Ou Z, Cooper ML, Eng P, Li J, Gu Y, Stratton RF, Chinault AC, Shaw CA, Sutton VR, Cheung SW, Nelson DL. Chromosomal microarray analysis (CMA) detects a large X chromosome deletion including FMR1, FMR2, and IDS in a female patient with mental retardation. Am J Med Genet A. 2007 Jun 15; 143A(12):1358-65. PMID: 17506108.
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    95. Luiz Oliveira Penido M, Resende DM, Vianello MA, Humberto da Silveira Bordin F, Jacinto AA, Dias WD, Montesano MA, Nelson DL, Marcos Zech Coelho P, Vasconcelos EG. A new series of schistosomicide drugs, the alkylaminoalkanethiosulfuric acids, partially inhibit the activity of Schistosoma mansoni ATP diphosphohydrolase. Eur J Pharmacol. 2007 Sep 10; 570(1-3):10-7. PMID: 17588561.
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    96. Sekine H, Ferreira RC, Pan-Hammarström Q, Graham RR, Ziemba B, de Vries SS, Liu J, Hippen K, Koeuth T, Ortmann W, Iwahori A, Elliott MK, Offer S, Skon C, Du L, Novitzke J, Lee AT, Zhao N, Tompkins JD, Altshuler D, Gregersen PK, Cunningham-Rundles C, Harris RS, Her C, Nelson DL, Hammarström L, Gilkeson GS, Behrens TW. Role for Msh5 in the regulation of Ig class switch recombination. Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17):7193-8. PMID: 17409188.
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    97. Pan-Hammarström Q, Salzer U, Du L, Björkander J, Cunningham-Rundles C, Nelson DL, Bacchelli C, Gaspar HB, Offer S, Behrens TW, Grimbacher B, Hammarström L. Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency. Nat Genet. 2007 Apr; 39(4):429-30. PMID: 17392797.
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    98. Lopez-Granados E, Temmerman ST, Wu L, Reynolds JC, Follmann D, Liu S, Nelson DL, Rauch F, Jain A. Osteopenia in X-linked hyper-IgM syndrome reveals a regulatory role for CD40 ligand in osteoclastogenesis. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5056-61. PMID: 17360404.
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    99. de Araújo SC, de Mattos AC, Teixeira HF, Coelho PM, Nelson DL, de Oliveira MC. Improvement of in vitro efficacy of a novel schistosomicidal drug by incorporation into nanoemulsions. Int J Pharm. 2007 Jun 07; 337(1-2):307-15. PMID: 17292573.
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    100. Stewart DM, Tian L, Notarangelo LD, Nelson DL. X-linked hypogammaglobulinemia and isolated growth hormone deficiency: an update. Immunol Res. 2007; 38(1-3):391-9. PMID: 17917049.
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    101. Wainscott DB, Little SP, Yin T, Tu Y, Rocco VP, He JX, Nelson DL. Pharmacologic characterization of the cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1. J Pharmacol Exp Ther. 2007 Jan; 320(1):475-85. PMID: 17038507.
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    102. Nishijima I, Yamagata T, Spencer CM, Weeber EJ, Alekseyenko O, Sweatt JD, Momoi MY, Ito M, Armstrong DL, Nelson DL, Paylor R, Bradley A. Secretin receptor-deficient mice exhibit impaired synaptic plasticity and social behavior. Hum Mol Genet. 2006 Nov 01; 15(21):3241-50. PMID: 17008357.
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    103. Musumeci SA, Calabrese G, Bonaccorso CM, D'Antoni S, Brouwer JR, Bakker CE, Elia M, Ferri R, Nelson DL, Oostra BA, Catania MV. Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes. Exp Neurol. 2007 Jan; 203(1):233-40. PMID: 17007840.
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    104. Moreira LS, Piló-Veloso D, de Mello RT, Coelho PM, Nelson DL. A study of the activity of 2-(alkylamino)-1-phenyl-1-ethanethiosulfuric acids against infection by Schistosoma mansoni in a murine model. Trans R Soc Trop Med Hyg. 2007 Apr; 101(4):385-90. PMID: 16979201.
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    105. Nelson DL. Critiquing the logic of the domain section of the Occupational therapy practice framework: domain and process. Am J Occup Ther. 2006 Sep-Oct; 60(5):511-23. PMID: 17022339.
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    106. Spencer CM, Serysheva E, Yuva-Paylor LA, Oostra BA, Nelson DL, Paylor R. Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins. Hum Mol Genet. 2006 Jun 15; 15(12):1984-94. PMID: 16675531.
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    107. Nelson DL. NEMO, NFkappaB signaling and incontinentia pigmenti. Curr Opin Genet Dev. 2006 Jun; 16(3):282-8. PMID: 16647846.
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    108. Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Buhay CJ, Chen R, Cree A, Ding Y, Dugan-Rocha S, Gill R, Gunaratne P, Harris RA, Hawes AC, Hernandez J, Hodgson AV, Hume J, Jackson A, Khan ZM, Kovar-Smith C, Lewis LR, Lozado RJ, Metzker ML, Milosavljevic A, Miner GR, Morgan MB, Nazareth LV, Scott G, Sodergren E, Song XZ, Steffen D, Wei S, Wheeler DA, Wright MW, Worley KC, Yuan Y, Zhang Z, Adams CQ, Ansari-Lari MA, Ayele M, Brown MJ, Chen G, Chen Z, Clendenning J, Clerc-Blankenburg KP, Chen R, Chen Z, Davis C, Delgado O, Dinh HH, Dong W, Draper H, Ernst S, Fu G, Gonzalez-Garay ML, Garcia DK, Gillett W, Gu J, Hao B, Haugen E, Havlak P, He X, Hennig S, Hu S, Huang W, Jackson LR, Jacob LS, Kelly SH, Kube M, Levy R, Li Z, Liu B, Liu J, Liu W, Lu J, Maheshwari M, Nguyen BV, Okwuonu GO, Palmeiri A, Pasternak S, Perez LM, Phelps KA, Plopper FJ, Qiang B, Raymond C, Rodriguez R, Saenphimmachak C, Santibanez J, Shen H, Shen Y, Subramanian S, Tabor PE, Verduzco D, Waldron L, Wang J, Wang J, Wang Q, Williams GA, Wong GK, Yao Z, Zhang J, Zhang X, Zhao G, Zhou J, Zhou Y, Nelson D, Lehrach H, Reinhardt R, Naylor SL, Yang H, Olson M, Weinstock G, Gibbs RA. The DNA sequence, annotation and analysis of human chromosome 3. Nature. 2006 Apr 27; 440(7088):1194-8. PMID: 16641997.
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    109. Moberg-Mogren E, Nelson DL. Evaluating the quality of reporting occupational therapy randomized controlled trials by expanding the CONSORT criteria. Am J Occup Ther. 2006 Mar-Apr; 60(2):226-35. PMID: 16596926.
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    110. Magalhães HP, Magalhães A, Juliano L, Nelson DL, Rogana E. Mechanism of action and determination of the best substrate for a thrombin-like enzyme from Lachesis muta muta venom by regression analysis of the kinetic parameters determined with peptidyl p-nitroanilide substrates. Toxicon. 2006 Mar 15; 47(4):453-8. PMID: 16488459.
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    111. Nelson DL, Gehlert DR. Central nervous system biogenic amine targets for control of appetite and energy expenditure. Endocrine. 2006 Feb; 29(1):49-60. PMID: 16622292.
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    112. Stewart DM, Tian L, Notarangelo LD, Nelson DL. Update on X-linked hypogammaglobulinemia with isolated growth hormone deficiency. Curr Opin Allergy Clin Immunol. 2005 Dec; 5(6):510-2. PMID: 16264330.
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    113. Matsuura T, Fang P, Pearson CE, Jayakar P, Ashizawa T, Roa BB, Nelson DL. Interruptions in the expanded ATTCT repeat of spinocerebellar ataxia type 10: repeat purity as a disease modifier? Am J Hum Genet. 2006 Jan; 78(1):125-9. PMID: 16385455.
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    114. Yu F, Sabeti PC, Hardenbol P, Fu Q, Fry B, Lu X, Ghose S, Vega R, Perez A, Pasternak S, Leal SM, Willis TD, Nelson DL, Belmont J, Gibbs RA. Positive selection of a pre-expansion CAG repeat of the human SCA2 gene. PLoS Genet. 2005 Sep; 1(3):e41. PMID: 16205789.
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    115. Rasmussen K, Benvenga MJ, Bymaster FP, Calligaro DO, Cohen IR, Falcone JF, Hemrick-Luecke SK, Martin FM, Moore NA, Nisenbaum LK, Schaus JM, Sundquist SJ, Tupper DE, Wiernicki TR, Nelson DL. Preclinical pharmacology of FMPD [6-fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: a potential novel antipsychotic with lower histamine H1 receptor affinity than olanzapine. J Pharmacol Exp Ther. 2005 Dec; 315(3):1265-77. PMID: 16141369.
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    116. Wainscott DB, Krushinski JH, Audia JE, Schaus JM, Zgombick JM, Lucaites VL, Nelson DL. [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar; 371(3):169-77. PMID: 15900510.
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    117. Lucaites VL, Krushinski JH, Schaus JM, Audia JE, Nelson DL. [3H]LY334370, a novel radioligand for the 5-HT1F receptor. II. Autoradiographic localization in rat, guinea pig, monkey and human brain. Naunyn Schmiedebergs Arch Pharmacol. 2005 Mar; 371(3):178-84. PMID: 15900511.
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    118. Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Glöckner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, Müller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR. The DNA sequence of the human X chromosome. Nature. 2005 Mar 17; 434(7031):325-37. PMID: 15772651.
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    119. Zhang D, Kohlman D, Krushinski J, Liang S, Ying BP, Reilly JE, Dinn SR, Wainscott DB, Nutter S, Gough W, Nelson DL, Schaus JM, Xu YC. Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists. Bioorg Med Chem Lett. 2004 Dec 20; 14(24):6011-6. PMID: 15546719.
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    120. Nelson DL, Gibbs RA. Genetics. The critical region in trisomy 21. Science. 2004 Oct 22; 306(5696):619-21. PMID: 15499000.
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    121. Jin Y, Mazza C, Christie JR, Giliani S, Fiorini M, Mella P, Gandellini F, Stewart DM, Zhu Q, Nelson DL, Notarangelo LD, Ochs HD. Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlation. Blood. 2004 Dec 15; 104(13):4010-9. PMID: 15284122.
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    122. Ariga T, Nakajima M, Yoshida J, Yamato K, Nagatoshi Y, Yanai F, Caviles AP, Nelson DL, Sakiyama Y. Confirming or excluding the diagnosis of Wiskott-Aldrich syndrome in children with thrombocytopenia of an unknown etiology. J Pediatr Hematol Oncol. 2004 Jul; 26(7):435-40. PMID: 15218418.
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    123. Rocco VP, Spinazze PG, Kohn TJ, Honigschmidt NA, Nelson DL, Bradley Wainscott D, Ahmad LJ, Shaw J, Threlkeld PG, Wong DT, Takeuchi K. Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 4. Bioorg Med Chem Lett. 2004 May 17; 14(10):2653-6. PMID: 15109671.
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    124. Wada T, Schurman SH, Jagadeesh GJ, Garabedian EK, Nelson DL, Candotti F. Multiple patients with revertant mosaicism in a single Wiskott-Aldrich syndrome family. Blood. 2004 Sep 01; 104(5):1270-2. PMID: 15142877.
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    125. Mientjes EJ, Willemsen R, Kirkpatrick LL, Nieuwenhuizen IM, Hoogeveen-Westerveld M, Verweij M, Reis S, Bardoni B, Hoogeveen AT, Oostra BA, Nelson DL. Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo. Hum Mol Genet. 2004 Jul 01; 13(13):1291-302. PMID: 15128702.
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    126. Matsuura T, Fang P, Lin X, Khajavi M, Tsuji K, Rasmussen A, Grewal RP, Achari M, Alonso ME, Pulst SM, Zoghbi HY, Nelson DL, Roa BB, Ashizawa T. Somatic and germline instability of the ATTCT repeat in spinocerebellar ataxia type 10. Am J Hum Genet. 2004 Jun; 74(6):1216-24. PMID: 15127363.
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    127. Meyer SE, Nelson DL, Carlson SL. Ecological genetics of vernalization response in Bromus tectorum L. (Poaceae). Ann Bot. 2004 Jun; 93(6):653-63. PMID: 15087300.
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    128. Larocca MC, Shanks RA, Tian L, Nelson DL, Stewart DM, Goldenring JR. AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus. Mol Biol Cell. 2004 Jun; 15(6):2771-81. PMID: 15047863.
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    129. Gulino AV, Moratto D, Sozzani S, Cavadini P, Otero K, Tassone L, Imberti L, Pirovano S, Notarangelo LD, Soresina R, Mazzolari E, Nelson DL, Notarangelo LD, Badolato R. Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome. Blood. 2004 Jul 15; 104(2):444-52. PMID: 15026312.
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    130. Bai F, Yin T, Johnstone EM, Su C, Varga G, Little SP, Nelson DL. Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor. Eur J Pharmacol. 2004 Jan 26; 484(2-3):127-39. PMID: 14744596.
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    131. Mathes BM, Hudziak KJ, Schaus JM, Xu YC, Nelson DL, Wainscott DB, Nutter SE, Gough WH, Branchek TA, Zgombick JM, Filla SA. Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists. Bioorg Med Chem Lett. 2004 Jan 05; 14(1):167-70. PMID: 14684321.
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    132. Jin P, Zarnescu DC, Ceman S, Nakamoto M, Mowrey J, Jongens TA, Nelson DL, Moses K, Warren ST. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci. 2004 Feb; 7(2):113-7. PMID: 14703574.
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    133. Nelson DL, Mathiowetz V. Randomized controlled trials to investigate occupational therapy research questions. Am J Occup Ther. 2004 Jan-Feb; 58(1):24-34. PMID: 14763633.
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    134. Miller BK, Nelson D. Constructing a program development proposal for community-based practice: a valuable learning experience for occupational therapy students. Occup Ther Health Care. 2004; 18(1-2):137-50. PMID: 23944673.
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    135. Koch S, Hemrick-Luecke SK, Thompson LK, Evans DC, Threlkeld PG, Nelson DL, Perry KW, Bymaster FP. Comparison of effects of dual transporter inhibitors on monoamine transporters and extracellular levels in rats. Neuropharmacology. 2003 Dec; 45(7):935-44. PMID: 14573386.
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    136. Qin H, Yamada M, Tian L, Stewart DM, Gulino AV, Nelson DL. Tracking gene expression in primary immunodeficiencies. Curr Opin Allergy Clin Immunol. 2003 Dec; 3(6):437-42. PMID: 14612667.
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    137. Takeuchi K, Kohn TJ, Honigschmidt NA, Rocco VP, Spinazze PG, Atkinson ST, Hertel LW, Nelson DL, Wainscott DB, Ahmad LJ, Shaw J, Threlkeld PG, Wong DT. Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 3. Bioorg Med Chem Lett. 2003 Nov 17; 13(22):3939-42. PMID: 14592479.
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    138. Stewart DM, McAvoy MJ, Hilbert DM, Nelson DL. B lymphocytes from individuals with common variable immunodeficiency respond to B lymphocyte stimulator (BLyS protein) in vitro. Clin Immunol. 2003 Nov; 109(2):137-43. PMID: 14597212.
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    139. Takeuchi K, Kohn TJ, Honigschmidt NA, Rocco VP, Spinazze PG, Koch DJ, Atkinson ST, Hertel LW, Nelson DL, Wainscott DB, Ahmad LJ, Shaw J, Threlkeld PG, Wong DT. Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT(1A) receptor antagonism/SSRI activities. Part 2. Bioorg Med Chem Lett. 2003 Jul 21; 13(14):2393-7. PMID: 12824042.
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    140. Filla SA, Mathes BM, Johnson KW, Phebus LA, Cohen ML, Nelson DL, Zgombick JM, Erickson JA, Schenck KW, Wainscott DB, Branchek TA, Schaus JM. Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides. J Med Chem. 2003 Jul 03; 46(14):3060-71. PMID: 12825944.
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    141. Takeuchi K, Kohn TJ, Honigschmidt NA, Rocco VP, Spinazze PG, Koch DJ, Nelson DL, Wainscott DB, Ahmad LJ, Shaw J, Threlkeld PG, Wong DT. Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1. Bioorg Med Chem Lett. 2003 Jun 02; 13(11):1903-5. PMID: 12749894.
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    142. Wada T, Konno A, Schurman SH, Garabedian EK, Anderson SM, Kirby M, Nelson DL, Candotti F. Second-site mutation in the Wiskott-Aldrich syndrome (WAS) protein gene causes somatic mosaicism in two WAS siblings. J Clin Invest. 2003 May; 111(9):1389-97. PMID: 12727931.
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    143. Wang Q, Gu Y, Ferguson JM, Chen Q, Boatwright S, Gardiner J, Below C, Espinosa J, Nelson DL, Shaffer LG. Cytogenetic analysis of obsessive-compulsive disorder (OCD): identification of a FRAXE fragile site. Am J Med Genet A. 2003 Apr 01; 118A(1):25-8. PMID: 12605436.
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    144. Peterson CQ, Nelson DL. Effect of an occupational intervention on printing in children with economic disadvantages. Am J Occup Ther. 2003 Mar-Apr; 57(2):152-60. PMID: 12674306.
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    145. Gibbs RA, Nelson DL. Human genetics. Primate shadow play. Science. 2003 Feb 28; 299(5611):1331-3. PMID: 12610290.
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    146. Koch S, Perry KW, Nelson DL, Conway RG, Threlkeld PG, Bymaster FP. R-fluoxetine increases extracellular DA, NE, as well as 5-HT in rat prefrontal cortex and hypothalamus: an in vivo microdialysis and receptor binding study. Neuropsychopharmacology. 2002 Dec; 27(6):949-59. PMID: 12464452.
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    147. Bonnen PE, Wang PJ, Kimmel M, Chakraborty R, Nelson DL. Haplotype and linkage disequilibrium architecture for human cancer-associated genes. Genome Res. 2002 Dec; 12(12):1846-53. PMID: 12466288.
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    148. Bymaster FP, Katner JS, Nelson DL, Hemrick-Luecke SK, Threlkeld PG, Heiligenstein JH, Morin SM, Gehlert DR, Perry KW. Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology. 2002 Nov; 27(5):699-711. PMID: 12431845.
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    149. Melville LL, Baltic TA, Bettcher TW, Nelson DL. Patients' perspectives on the self-identified goals assessment. Am J Occup Ther. 2002 Nov-Dec; 56(6):650-9. PMID: 12458857.
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    150. Peier AM, Nelson DL. Instability of a premutation-sized CGG repeat in FMR1 YAC transgenic mice. Genomics. 2002 Oct; 80(4):423-32. PMID: 12376097.
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    151. Yamaguchi K, Ariga T, Yamada M, Nelson DL, Kobayashi R, Kobayashi C, Noguchi Y, Ito Y, Katamura K, Nagatoshi Y, Kondo S, Katoh H, Sakiyama Y. Mixed chimera status of 12 patients with Wiskott-Aldrich syndrome (WAS) after hematopoietic stem cell transplantation: evaluation by flow cytometric analysis of intracellular WAS protein expression. Blood. 2002 Aug 15; 100(4):1208-14. PMID: 12149199.
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    152. Yamagata T, Aradhya S, Mori M, Inoue K, Momoi MY, Nelson DL. The human secretin gene: fine structure in 11p15.5 and sequence variation in patients with autism. Genomics. 2002 Aug; 80(2):185-94. PMID: 12160732.
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    153. Resende JT, Maluf WR, Cardoso Md, Nelson DL, Faria MV. Inheritance of acylsugar contents in tomatoes derived from an interspecific cross with the wild tomato Lycopersicon pennellii and their effect on spider mite repellence. Genet Mol Res. 2002 Jun 30; 1(2):106-16. PMID: 14963836.
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    154. Morales J, Hiesinger PR, Schroeder AJ, Kume K, Verstreken P, Jackson FR, Nelson DL, Hassan BA. Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain. Neuron. 2002 Jun 13; 34(6):961-72. PMID: 12086643.
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    155. Wada T, Jagadeesh GJ, Nelson DL, Candotti F. Retrovirus-mediated WASP gene transfer corrects Wiskott-Aldrich syndrome T-cell dysfunction. Hum Gene Ther. 2002 Jun 10; 13(9):1039-46. PMID: 12067437.
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    156. Zoghbi HY, Nelson D. Scientific and technological synergy: Baylor College of Medicine and the Mental Retardation Research Center. Int J Dev Neurosci. 2002 Jun-Aug; 20(3-5):467-8. PMID: 12175888.
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    157. Kim K, Son M, Peterson JB, Nelson DL. Ca(2+)-binding proteins of cilia and infraciliary lattice of Paramecium tetraurelia: their phosphorylation by purified endogenous Ca(2+)-dependent protein kinases. J Cell Sci. 2002 May 01; 115(Pt 9):1973-84. PMID: 11956328.
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    158. Ward NS, Lin DY, Nelson DL, Houtchens J, Schwartz WA, Klinger JR, Hill NS, Levy MM. Successful determination of lower inflection point and maximal compliance in a population of patients with acute respiratory distress syndrome. Crit Care Med. 2002 May; 30(5):963-8. PMID: 12006788.
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    159. Trikka D, Fang Z, Renwick A, Jones SH, Chakraborty R, Kimmel M, Nelson DL. Complex SNP-based haplotypes in three human helicases: implications for cancer association studies. Genome Res. 2002 Apr; 12(4):627-39. PMID: 11932247.
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    160. Gu Y, McIlwain KL, Weeber EJ, Yamagata T, Xu B, Antalffy BA, Reyes C, Yuva-Paylor L, Armstrong D, Zoghbi H, Sweatt JD, Paylor R, Nelson DL. Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice. J Neurosci. 2002 Apr 01; 22(7):2753-63. PMID: 11923441.
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    161. Notarangelo LD, Mazza C, Giliani S, D'Aria C, Gandellini F, Ravelli C, Locatelli MG, Nelson DL, Ochs HD, Notarangelo LD. Missense mutations of the WASP gene cause intermittent X-linked thrombocytopenia. Blood. 2002 Mar 15; 99(6):2268-9. PMID: 11877312.
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    162. Aradhya S, Woffendin H, Bonnen P, Heiss NS, Yamagata T, Esposito T, Bardaro T, Poustka A, D'Urso M, Kenwrick S, Nelson DL. Physical and genetic characterization reveals a pseudogene, an evolutionary junction, and unstable loci in distal Xq28. Genomics. 2002 Jan; 79(1):31-40. PMID: 11827455.
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    163. Nelson DL, Cipriani DJ, Thomas JJ. Physical therapy and occupational therapy: partners in rehabilitation for persons with movement impairments. Occup Ther Health Care. 2002; 15(3-4):35-57. PMID: 23952022.
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    164. Nelson DL, Melville LL, Wilkerson JD, Magness RA, Grech JL, Rosenberg JA. Interrater reliability, concurrent validity, responsiveness, and predictive validity of the Melville-Nelson Self-Care Assessment. Am J Occup Ther. 2002 Jan-Feb; 56(1):51-9. PMID: 11833401.
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    165. Carpenter JW, Laethem C, Hubbard FR, Eckols TK, Baez M, McClure D, Nelson DL, Johnston PA. Configuring radioligand receptor binding assays for HTS using scintillation proximity assay technology. Methods Mol Biol. 2002; 190:31-49. PMID: 12029825.
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    166. Sterioff S, Nelson DL. A teacher of surgical thought. Surgery. 2002 Jan; 131(1):117-8. PMID: 11812974.
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