BRIAN GILBERT

TitleAssociate Professor Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Virology & Microbiology
AddressOne Baylor Plaza
Houston, TX 77030
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gilbert BW, Tabaka CA. Indirect antiplatelet effects of rivaroxaban in a patient with intracranial hemorrhage: An underappreciated coagulopathy of factor Xa inhibitors? Am J Emerg Med. 2021 Jul 02. PMID: 34244010.
      Citations:    Fields:    
    2. Zimmerman DE, Sarangarm P, Brown CS, Faine B, Flack T, Gilbert BW, Howington GT, Kelly G, Laub J, Porter BA, Slocum GW, Rech MA. Staying InformED: Top emergency Medicine pharmacotherapy articles of 2020. Am J Emerg Med. 2021 11; 49:200-205. PMID: 34139435.
      Citations:    Fields:    
    3. Blunck BN, Aideyan L, Ye X, Avadhanula V, Ferlic-Stark L, Zechiedrich L, Gilbert BE, Piedra PA. A prospective surveillance study on the kinetics of the humoral immune response to the respiratory syncytial virus fusion protein in adults in Houston, Texas. Vaccine. 2021 02 22; 39(8):1248-1256. PMID: 33509697.
      Citations:    Fields:    Translation:HumansCells
    4. Xu C, Lau CL, Clark J, Rafferty AC, Mills DJ, Ramsey L, Gilbert B, Doi SAR, Furuya-Kanamori L. Immunogenicity after pre- and post-exposure rabies vaccination: A systematic review and dose-response meta-analysis. Vaccine. 2021 02 12; 39(7):1044-1050. PMID: 33478786.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    5. Gilbert BW, Dingman JS, Huffman JB. Utilization of lysis percentage via thromboelastography for tissue plasminogen activator-induced symptomatic intracranial hemorrhage. Am J Emerg Med. 2021 05; 43:31-34. PMID: 33493994.
      Citations:    Fields:    Translation:Humans
    6. Rao L, De La Rosa I, Xu Y, Sha Y, Bhattacharya A, Holtzman MJ, Gilbert BE, Eissa NT. Pseudomonas aeruginosa survives in epithelia by ExoS-mediated inhibition of autophagy and mTOR. EMBO Rep. 2021 02 03; 22(2):e50613. PMID: 33345425.
      Citations: 1     Fields:    Translation:AnimalsCells
    7. Gilbert BW, Dively B, Reeder JA, Philip GJ. Challenges in determining minor head trauma risks in patients on DOACs. Am J Emerg Med. 2021 04; 42:233-234. PMID: 33608166.
      Citations:    Fields:    Translation:Humans
    8. Gilbert BW, Morton L, Huffman JB, Roemer K, Potter A, Cassidy CD, Vasquez DG. Modified version of the American College of Cardiology's recommendation for low-dose prothrombin complex concentrate is effective for warfarin reversal. Am J Emerg Med. 2020 04; 38(4):806-809. PMID: 31864879.
      Citations:    Fields:    Translation:Humans
    9. Madison MC, Landers CT, Gu BH, Chang CY, Tung HY, You R, Hong MJ, Baghaei N, Song LZ, Porter P, Putluri N, Salas R, Gilbert BE, Levental I, Campen MJ, Corry DB, Kheradmand F. Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine. J Clin Invest. 2019 10 01; 129(10):4290-4304. PMID: 31483291.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    10. Gilbert BW, Dingman JS, Reeder JA, Le SM, Ponce PJ, Philip GJ. Does a dose relationship exist with prothrombin complex and factor Xa inhibitor reversal? An alternate perspective of Yohe et al. Am J Emerg Med. 2020 03; 38(3):686-687. PMID: 31522926.
      Citations:    Fields:    
    11. Gilbert BW, Adams TR, Reynolds TR, Moran DA, Philip GJ. Utilization of thromboelastography and a low molecular weight heparin anti-Xa assay for guidance in apixaban reversal: A case report. Am J Emerg Med. 2019 10; 37(10):1991.e1-1991.e3. PMID: 31375354.
      Citations:    Fields:    Translation:Humans
    12. Gilbert BW, Reeder JA, Alkhalifah MA, Moran DA, Corvino MA. Throwing it in reverse: An update on reversal of oral factor Xa inhibitors. Am J Emerg Med. 2019 10; 37(10):1978-1980. PMID: 30987915.
      Citations:    Fields:    Translation:Humans
    13. Gilbert BE, Patel N, Lu H, Liu Y, Guebre-Xabier M, Piedra PA, Glenn G, Ellingsworth L, Smith G. Respiratory syncytial virus fusion nanoparticle vaccine immune responses target multiple neutralizing epitopes that contribute to protection against wild-type and palivizumab-resistant mutant virus challenge. Vaccine. 2018 12 18; 36(52):8069-8078. PMID: 30389195.
      Citations: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    14. Knight JM, Mandal P, Morlacchi P, Mak G, Li E, Madison M, Landers C, Saxton B, Felix E, Gilbert B, Sederstrom J, Varadhachary A, Singh MM, Chatterjee D, Corry DB, McMurray JS. Small molecule targeting of the STAT5/6 Src homology 2 (SH2) domains to inhibit allergic airway disease. J Biol Chem. 2018 06 29; 293(26):10026-10040. PMID: 29739850.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    15. Liang D, Tian L, You R, Halpert MM, Konduri V, Baig YC, Paust S, Kim D, Kim S, Jia F, Huang S, Zhang X, Kheradmand F, Corry DB, Gilbert BE, Levitt JM, Decker WK. AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity. Front Immunol. 2017; 8:1801. PMID: 29379495.
      Citations: 6     Fields:    
    16. Koire A, Gilbert BE, Sucgang R, Zechiedrich L. Correction: Repurposed Transcriptomic Data Reveal Small Viral RNA Produced by Influenza Virus during Infection in Mice. PLoS One. 2017; 12(12):e0189384. PMID: 29206873.
      Citations:    Fields:    
    17. Leiva-Juarez MM, Kirkpatrick CT, Gilbert BE, Scott B, Tuvim MJ, Dickey BF, Evans SE, Markesich D. Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir. Eur J Pharmacol. 2018 Jan 05; 818:191-197. PMID: 29066417.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    18. Stobart CC, Rostad CA, Ke Z, Dillard RS, Hampton CM, Strauss JD, Yi H, Hotard AL, Meng J, Pickles RJ, Sakamoto K, Lee S, Currier MG, Moin SM, Graham BS, Boukhvalova MS, Gilbert BE, Blanco JC, Piedra PA, Wright ER, Moore ML. A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation. Nat Commun. 2016 12 21; 7:13916. PMID: 28000669.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    19. Koire A, Gilbert BE, Sucgang R, Zechiedrich L. Repurposed Transcriptomic Data Reveal Small Viral RNA Produced by Influenza Virus during Infection in Mice. PLoS One. 2016; 11(10):e0165729. PMID: 27788253.
      Citations: 3     Fields:    Translation:AnimalsCells
    20. Rostad CA, Stobart CC, Gilbert BE, Pickles RJ, Hotard AL, Meng J, Blanco JCG, Moin SM, Graham BS, Piedra PA, Moore ML. A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton Rats. J Virol. 2016 08 15; 90(16):7508-7518. PMID: 27279612.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    21. Perron M, Stray K, Kinkade A, Theodore D, Lee G, Eisenberg E, Sangi M, Gilbert BE, Jordan R, Piedra PA, Toms GL, Mackman R, Cihlar T. GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1264-73. PMID: 26666922.
      Citations: 22     Fields:    Translation:HumansCells
    22. Detalle L, Stohr T, Palomo C, Piedra PA, Gilbert BE, Mas V, Millar A, Power UF, Stortelers C, Allosery K, Melero JA, Depla E. Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection. Antimicrob Agents Chemother. 2016 01; 60(1):6-13. PMID: 26438495.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    23. Evans CW, Atkins C, Pathak A, Gilbert BE, Noah JW. Benzimidazole analogs inhibit respiratory syncytial virus G protein function. Antiviral Res. 2015 Sep; 121:31-8. PMID: 26116756.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    24. Kim E, Okada K, Beeler JA, Crim RL, Steitz J, Piedra PA, Gilbert BE, Gambotto A. Correction for Kim et al., development of an adenovirus-based respiratory syncytial virus vaccine: preclinical evaluation of efficacy, immunogenicity, and enhanced disease in a cotton rat model. J Virol. 2015 May; 89(9):5193. PMID: 25841050.
      Citations:    Fields:    
    25. Mackman RL, Sangi M, Sperandio D, Parrish JP, Eisenberg E, Perron M, Hui H, Zhang L, Siegel D, Yang H, Saunders O, Boojamra C, Lee G, Samuel D, Babaoglu K, Carey A, Gilbert BE, Piedra PA, Strickley R, Iwata Q, Hayes J, Stray K, Kinkade A, Theodore D, Jordan R, Desai M, Cihlar T. Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study. J Med Chem. 2015 Feb 26; 58(4):1630-43. PMID: 25574686.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    26. Schepens B, Sedeyn K, Vande Ginste L, De Baets S, Schotsaert M, Roose K, Houspie L, Van Ranst M, Gilbert B, van Rooijen N, Fiers W, Piedra P, Saelens X. Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein. EMBO Mol Med. 2014 Nov; 6(11):1436-54. PMID: 25298406.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    27. Ressler SJ, Dang TD, Wu SM, Tse DY, Gilbert BE, Vyakarnam A, Yang F, Schauer IG, Barron DA, Rowley DR. WFDC1 is a key modulator of inflammatory and wound repair responses. Am J Pathol. 2014 Nov; 184(11):2951-64. PMID: 25219356.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    28. Chen M, Hong MJ, Sun H, Wang L, Shi X, Gilbert BE, Corry DB, Kheradmand F, Wang J. Essential role for autophagy in the maintenance of immunological memory against influenza infection. Nat Med. 2014 May; 20(5):503-10. PMID: 24747745.
      Citations: 75     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    29. Hiatt A, Bohorova N, Bohorov O, Goodman C, Kim D, Pauly MH, Velasco J, Whaley KJ, Piedra PA, Gilbert BE, Zeitlin L. Glycan variants of a respiratory syncytial virus antibody with enhanced effector function and in vivo efficacy. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):5992-7. PMID: 24711420.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    30. Kim E, Okada K, Beeler JA, Crim RL, Piedra PA, Gilbert BE, Gambotto A. Development of an adenovirus-based respiratory syncytial virus vaccine: preclinical evaluation of efficacy, immunogenicity, and enhanced disease in a cotton rat model. J Virol. 2014 May; 88(9):5100-8. PMID: 24574396.
      Citations: 13     Fields:    Translation:AnimalsCells
    31. Chang JH, Hu H, Jin J, Puebla-Osorio N, Xiao Y, Gilbert BE, Brink R, Ullrich SE, Sun SC. TRAF3 regulates the effector function of regulatory T cells and humoral immune responses. J Exp Med. 2014 Jan 13; 211(1):137-51. PMID: 24378539.
      Citations: 34     Fields:    Translation:AnimalsCells
    32. Konduri V, Decker WK, Halpert MM, Gilbert B, Safdar A. Modeling dendritic cell vaccination for influenza prophylaxis: potential applications for niche populations. J Infect Dis. 2013 Jun 01; 207(11):1764-72. PMID: 23460750.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    33. Zeitlin L, Bohorov O, Bohorova N, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Barnard DL, Bates JT, Crowe JE, Piedra PA, Gilbert BE. Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model. MAbs. 2013 Mar-Apr; 5(2):263-9. PMID: 23396091.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    34. Tuvim MJ, Gilbert BE, Dickey BF, Evans SE. Synergistic TLR2/6 and TLR9 activation protects mice against lethal influenza pneumonia. PLoS One. 2012; 7(1):e30596. PMID: 22299046.
      Citations: 39     Fields:    Translation:AnimalsCells
    35. Latimer P, Menchaca M, Snyder RM, Yu W, Gilbert BE, Sanders BG, Kline K. Aerosol delivery of liposomal formulated paclitaxel and vitamin E analog reduces murine mammary tumor burden and metastases. Exp Biol Med (Maywood). 2009 Oct; 234(10):1244-52. PMID: 19657067.
      Citations: 12     Fields:    Translation:AnimalsCells
    36. Woo JK, Choi DS, Tran HT, Gilbert BE, Hong WK, Lee HY. Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis. Cancer Prev Res (Phila). 2009 Apr; 2(4):361-9. PMID: 19336726.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    37. Tuvim MJ, Evans SE, Clement CG, Dickey BF, Gilbert BE. Augmented lung inflammation protects against influenza A pneumonia. PLoS One. 2009; 4(1):e4176. PMID: 19137067.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    38. Gilbert BE, McLeay MT. MegaRibavirin aerosol for the treatment of influenza A virus infections in mice. Antiviral Res. 2008 Jun; 78(3):223-9. PMID: 18281104.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    39. Wyde PR, Laquerre S, Chetty SN, Gilbert BE, Nitz TJ, Pevear DC. Antiviral efficacy of VP14637 against respiratory syncytial virus in vitro and in cotton rats following delivery by small droplet aerosol. Antiviral Res. 2005 Oct; 68(1):18-26. PMID: 16112208.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    40. Zakharian TY, Seryshev A, Sitharaman B, Gilbert BE, Knight V, Wilson LJ. A fullerene-paclitaxel chemotherapeutic: synthesis, characterization, and study of biological activity in tissue culture. J Am Chem Soc. 2005 Sep 14; 127(36):12508-9. PMID: 16144396.
      Citations: 39     Fields:    Translation:HumansCells
    41. Lawson KA, Anderson K, Snyder RM, Simmons-Menchaca M, Atkinson J, Sun LZ, Bandyopadhyay A, Knight V, Gilbert BE, Sanders BG, Kline K. Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis. Cancer Chemother Pharmacol. 2004 Nov; 54(5):421-31. PMID: 15197487.
      Citations: 16     Fields:    Translation:AnimalsCells
    42. Verschraegen CF, Gilbert BE, Loyer E, Huaringa A, Walsh G, Newman RA, Knight V. Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignancies. Clin Cancer Res. 2004 Apr 01; 10(7):2319-26. PMID: 15073107.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    43. Koshkina NV, Golunski E, Roberts LE, Gilbert BE, Knight V. Cyclosporin A aerosol improves the anticancer effect of paclitaxel aerosol in mice. J Aerosol Med. 2004; 17(1):7-14. PMID: 15120008.
      Citations: 12     Fields:    Translation:Animals
    44. Wyde PR, Chetty SN, Timmerman P, Gilbert BE, Andries K. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov; 60(3):221-31. PMID: 14638398.
      Citations: 16     Fields:    Translation:AnimalsCells
    45. Lawson KA, Anderson K, Menchaca M, Atkinson J, Sun L, Knight V, Gilbert BE, Conti C, Sanders BG, Kline K. Novel vitamin E analogue decreases syngeneic mouse mammary tumor burden and reduces lung metastasis. Mol Cancer Ther. 2003 May; 2(5):437-44. PMID: 12748305.
      Citations: 26     Translation:HumansAnimalsCells
    46. Lee HY, Suh YA, Lee JI, Hassan KA, Mao L, Force T, Gilbert BE, Jacks T, Kurie JM. Inhibition of oncogenic K-ras signaling by aerosolized gene delivery in a mouse model of human lung cancer. Clin Cancer Res. 2002 Sep; 8(9):2970-5. PMID: 12231543.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    47. Gilbert BE, Seryshev A, Knight V, Brayton C. 9-nitrocamptothecin liposome aerosol: lack of subacute toxicity in dogs. Inhal Toxicol. 2002 Feb; 14(2):185-97. PMID: 12122579.
      Citations:    Fields:    Translation:Animals
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