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PHILIP HASTINGS

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Human Genetics
AddressOne Baylor Plaza
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    R01GM106373     (HASTINGS, PHILIP J ;LUPSKI, JAMES R.)Sep 5, 2014 - Feb 29, 2024
    NIH
    MUTATIONAL SIGNATURE(S) OF HUMAN GENOMIC REARRANGEMENT MECHANISMS
    Role: Principal Investigator
    R01GM064022     (HASTINGS, PHILIP J)Aug 1, 2001 - Apr 30, 2012
    NIH
    Mechanisms of Adaptive Amplification
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Yu Y, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yeast EndoG prevents genome instability by degrading extranuclear DNA species. Nat Commun. 2024 Sep 03; 15(1):7653. PMID: 39227600; PMCID: PMC11372161.
      Citations:    Fields:    Translation:AnimalsCells
    2. Yu Y, Wang X, Fox J, Li Q, Hastings PJ, Chen K, Ira G. RPA and Rad27 limit templated and inverted insertions at DNA breaks. bioRxiv. 2024 Mar 07. PMID: 38496432; PMCID: PMC10942419.
      Citations:    
    3. Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yeast EndoG prevents genome instability by degrading cytoplasmic DNA. Res Sq. 2024 Jan 05. PMID: 38260641; PMCID: PMC10802722.
      Citations:    
    4. Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yeast EndoG prevents genome instability by degrading cytoplasmic DNA. bioRxiv. 2023 Dec 13. PMID: 38168242; PMCID: PMC10760121.
      Citations:    
    5. Zhai Y, Pribis JP, Dooling SW, Garcia-Villada L, Minnick PJ, Xia J, Liu J, Mei Q, Fitzgerald DM, Herman C, Hastings PJ, Costa-Mattioli M, Rosenberg SM. Drugging evolution of antibiotic resistance at a regulatory network hub. Sci Adv. 2023 06 23; 9(25):eadg0188. PMID: 37352342; PMCID: PMC10289659.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Zhai Y, Minnick PJ, Pribis JP, Garcia-Villada L, Hastings PJ, Herman C, Rosenberg SM. ppGpp and RNA-polymerase backtracking guide antibiotic-induced mutable gambler cells. Mol Cell. 2023 04 20; 83(8):1298-1310.e4. PMID: 36965481; PMCID: PMC10317147.
      Citations: 1     Fields:    Translation:Cells
    7. Du H, Jolly A, Grochowski CM, Yuan B, Dawood M, Jhangiani SN, Li H, Muzny D, Fatih JM, Coban-Akdemir Z, Carlin ME, Scheuerle AE, Witzl K, Posey JE, Pendleton M, Harrington E, Juul S, Hastings PJ, Bi W, Gibbs RA, Sedlazeck FJ, Lupski JR, Carvalho CMB, Liu P. The multiple de novo copy number variant (MdnCNV) phenomenon presents with peri-zygotic DNA mutational signatures and multilocus pathogenic variation. Genome Med. 2022 10 27; 14(1):122. PMID: 36303224; PMCID: PMC9609164.
      Citations: 4     Fields:    Translation:Humans
    8. Pribis JP, Zhai Y, Hastings PJ, Rosenberg SM. Stress-Induced Mutagenesis, Gambler Cells, and Stealth Targeting Antibiotic-Induced Evolution. mBio. 2022 06 28; 13(3):e0107422. PMID: 35658528; PMCID: PMC9239211.
      Citations:    Fields:    Translation:Cells
    9. Mei Q, Fitzgerald DM, Liu J, Xia J, Pribis JP, Zhai Y, Nehring RB, Paiano J, Li H, Nussenzweig A, Hastings PJ, Rosenberg SM. Two mechanisms of chromosome fragility at replication-termination sites in bacteria. Sci Adv. 2021 06; 7(25). PMID: 34144978; PMCID: PMC8213236.
      Citations: 5     Fields:    Translation:HumansCells
    10. Pribis JP, Zhai Y, Lewin-Epstein O, Wang AZ, Liu J, Xia J, Mei Q, Fitzgerald DM, Bos J, Austin RH, Herman C, Bates D, Hadany L, Hastings PJ, Rosenberg SM, Garc?a-Villada L. Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response. Mol Cell. 2019 05 16; 74(4):785-800.e7. PMID: 30948267; PMCID: PMC6553487.
      Citations: 40     Fields:    Translation:Cells
    11. Beck CR, Carvalho CMB, Akdemir ZC, Sedlazeck FJ, Song X, Meng Q, Hu J, Doddapaneni H, Chong Z, Chen ES, Thornton PC, Liu P, Yuan B, Withers M, Jhangiani SN, Kalra D, Walker K, English AC, Han Y, Chen K, Muzny DM, Ira G, Shaw CA, Gibbs RA, Hastings PJ, Lupski JR. Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2. Cell. 2019 03 07; 176(6):1310-1324.e10. PMID: 30827684; PMCID: PMC6438178.
      Citations: 29     Fields:    Translation:HumansCells
    12. Xia J, Chiu LY, Nehring RB, Mei Q, Perez M, Zhai Y, Fitzgerald DM, Pribis JP, Wang Y, Hu CW, Powell RT, LaBonte SA, Jalali A, Lentzsch AM, Szafran AT, Joshi MC, Richters M, Gibson JL, Frisch RL, Hastings PJ, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C, Miller KM, Rosenberg SM, Bravo N??ez MA, Matadamas Guzm?n ML. Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. Cell. 2019 01 10; 176(1-2):127-143.e24. PMID: 30633903; PMCID: PMC6344048.
      Citations: 35     Fields:    Translation:HumansCells
    13. Kotlajich MV, Xia J, Zhai Y, Lin HY, Bradley CC, Shen X, Mei Q, Wang AZ, Lynn EJ, Shee C, Chen LT, Li L, Miller KM, Herman C, Hastings PJ, Rosenberg SM. Fluorescent fusions of the N protein of phage Mu label DNA damage in living cells. DNA Repair (Amst). 2018 12; 72:86-92. PMID: 30268364; PMCID: PMC6287932.
      Citations: 2     Fields:    Translation:Cells
    14. Correa R, Thornton PC, Rosenberg SM, Hastings PJ. Oxygen and RNA in stress-induced mutation. Curr Genet. 2018 Aug; 64(4):769-776. PMID: 29294174; PMCID: PMC6028306.
      Citations: 4     Fields:    Translation:HumansCells
    15. Hastings PJ, Rosenberg SM. A radical way to die. Nat Microbiol. 2017 12; 2(12):1582-1583. PMID: 29176695.
      Citations: 1     Fields:    Translation:Cells
    16. Moore JM, Correa R, Rosenberg SM, Hastings PJ. Persistent damaged bases in DNA allow mutagenic break repair in Escherichia coli. PLoS Genet. 2017 Jul; 13(7):e1006733. PMID: 28727736; PMCID: PMC5542668.
      Citations: 14     Fields:    Translation:Cells
    17. Fitzgerald DM, Hastings PJ, Rosenberg SM. Stress-Induced Mutagenesis: Implications in Cancer and Drug Resistance. Annu Rev Cancer Biol. 2017 Mar; 1:119-140. PMID: 29399660; PMCID: PMC5794033.
      Citations: 53     
    18. Xia J, Chen LT, Mei Q, Ma CH, Halliday JA, Lin HY, Magnan D, Pribis JP, Fitzgerald DM, Hamilton HM, Richters M, Nehring RB, Shen X, Li L, Bates D, Hastings PJ, Herman C, Jayaram M, Rosenberg SM. Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase. Sci Adv. 2016 Nov; 2(11):e1601605. PMID: 28090586; PMCID: PMC5222578.
      Citations: 17     Fields:    Translation:HumansCells
    19. Nehring RB, Gu F, Lin HY, Gibson JL, Blythe MJ, Wilson R, Hastings PJ, Louis EJ, Frisch RL, Hu JC, Rosenberg SM, Bravo N??ez MA. An ultra-dense library resource for rapid deconvolution of mutations that cause phenotypes in Escherichia coli. Nucleic Acids Res. 2016 Mar 18; 44(5):e41. PMID: 26578563; PMCID: PMC4797258.
      Citations: 10     Fields:    Translation:Cells
    20. Moore JM, Magnan D, Mojica AK, Bates D, Rosenberg SM, Hastings PJ, N??ez MA. Roles of Nucleoid-Associated Proteins in Stress-Induced Mutagenic Break Repair in Starving Escherichia coli. Genetics. 2015 Dec; 201(4):1349-62. PMID: 26500258; PMCID: PMC4676537.
      Citations: 10     Fields:    Translation:Cells
    21. Pfundt R, King DA, Lindsay SJ, Zuccherato LW, Macville MV, Liu P, Johnson D, Stankiewicz P, Brown CW, Shaw CA, Hurles ME, Ira G, Hastings PJ, Brunner HG, Lupski JR, Carvalho CM, DDD?Study. Absence of heterozygosity due to template switching during replicative rearrangements. Am J Hum Genet. 2015 Apr 02; 96(4):555-64. PMID: 25799105; PMCID: PMC4385179.
      Citations: 27     Fields:    Translation:HumansCells
    22. Shee C, Cox BD, Gu F, Luengas EM, Joshi MC, Chiu LY, Magnan D, Halliday JA, Frisch RL, Gibson JL, Nehring RB, Do HG, Hernandez M, Li L, Herman C, Hastings PJ, Bates D, Harris RS, Miller KM, Rosenberg SM. Engineered proteins detect spontaneous DNA breakage in human and bacterial cells. Elife. 2013 Oct 29; 2:e01222. PMID: 24171103; PMCID: PMC3809393.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    23. Pehlivan D, Ramocki MB, Fang P, Alleva B, Franco LM, Belmont JW, Hastings PJ, Lupski JR, Carvalho CM. Replicative mechanisms for CNV formation are error prone. Nat Genet. 2013 Nov; 45(11):1319-26. PMID: 24056715; PMCID: PMC3821386.
      Citations: 81     Fields:    Translation:HumansCells
    24. Wimberly H, Shee C, Thornton PC, Sivaramakrishnan P, Rosenberg SM, Hastings PJ. R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli. Nat Commun. 2013; 4:2115. PMID: 23828459; PMCID: PMC3715873.
      Citations: 69     Fields:    Translation:Cells
    25. Al Mamun AA, Lombardo MJ, Shee C, Lisewski AM, Gonzalez C, Lin D, Nehring RB, Saint-Ruf C, Gibson JL, Frisch RL, Lichtarge O, Hastings PJ, Rosenberg SM. Identity and function of a large gene network underlying mutagenic repair of DNA breaks. Science. 2012 Dec 07; 338(6112):1344-8. PMID: 23224554; PMCID: PMC3782309.
      Citations: 100     Fields:    Translation:Cells
    26. Moore JM, Wimberly H, Thornton PC, Rosenberg SM, Hastings PJ. Gross chromosomal rearrangement mediated by DNA replication in stressed cells: evidence from Escherichia coli. Ann N Y Acad Sci. 2012 Sep; 1267:103-9. PMID: 22954223; PMCID: PMC3442953.
      Citations: 1     Fields:    Translation:Cells
    27. Rosenberg SM, Shee C, Frisch RL, Hastings PJ. Stress-induced mutation via DNA breaks in Escherichia coli: a molecular mechanism with implications for evolution and medicine. Bioessays. 2012 Oct; 34(10):885-92. PMID: 22911060; PMCID: PMC3533179.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    28. Ira G, Hastings PJ. DNA breakage drives nuclear search. Nat Cell Biol. 2012 May 02; 14(5):448-50. PMID: 22552144; PMCID: PMC4495951.
      Citations: 5     Fields:    Translation:Cells
    29. Liu P, Carvalho CM, Hastings PJ, Lupski JR. Mechanisms for recurrent and complex human genomic rearrangements. Curr Opin Genet Dev. 2012 Jun; 22(3):211-20. PMID: 22440479; PMCID: PMC3378805.
      Citations: 155     Fields:    Translation:HumansCells
    30. Hastings PJ, Rosenberg SM. Genomic rearrangement in three dimensions. Nat Biotechnol. 2011 Dec 08; 29(12):1096-8. PMID: 22158363.
      Citations: 2     Fields:    Translation:HumansCells
    31. Eytan RI, Hastings PA, Holland BR, Hellberg ME. Reconciling molecules and morphology: molecular systematics and biogeography of Neotropical blennies (Acanthemblemaria). Mol Phylogenet Evol. 2012 Jan; 62(1):159-73. PMID: 22040767.
      Citations:    
    32. Liu P, Lacaria M, Zhang F, Withers M, Hastings PJ, Lupski JR. Frequency of nonallelic homologous recombination is correlated with length of homology: evidence that ectopic synapsis precedes ectopic crossing-over. Am J Hum Genet. 2011 Oct 07; 89(4):580-8. PMID: 21981782; PMCID: PMC3188830.
      Citations: 57     Fields:    Translation:HumansCells
    33. Carvalho CM, Ramocki MB, Pehlivan D, Franco LM, Gonzaga-Jauregui C, Fang P, McCall A, Pivnick EK, Hines-Dowell S, Seaver LH, Friehling L, Lee S, Smith R, Del Gaudio D, Withers M, Liu P, Cheung SW, Belmont JW, Zoghbi HY, Hastings PJ, Lupski JR. Inverted genomic segments and complex triplication rearrangements are mediated by inverted repeats in the human genome. Nat Genet. 2011 Oct 02; 43(11):1074-81. PMID: 21964572; PMCID: PMC3235474.
      Citations: 100     Fields:    Translation:HumansCells
    34. Liu P, Erez A, Nagamani SC, Dhar SU, Kolodziejska KE, Dharmadhikari AV, Cooper ML, Wiszniewska J, Zhang F, Withers MA, Bacino CA, Campos-Acevedo LD, Delgado MR, Freedenberg D, Garnica A, Grebe TA, Immken L, Lalani SR, McLean SD, Northrup H, Scaglia F, Strathearn L, Trapane P, Kang SH, Patel A, Cheung SW, Hastings PJ, Stankiewicz P, Lupski JR, Bi W, Hern?ndez-Almaguer D. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell. 2011 Sep 16; 146(6):889-903. PMID: 21925314; PMCID: PMC3242451.
      Citations: 196     Fields:    Translation:HumansCells
    35. Lin D, Gibson IB, Moore JM, Thornton PC, Leal SM, Hastings PJ. Global chromosomal structural instability in a subpopulation of starving Escherichia coli cells. PLoS Genet. 2011 Aug; 7(8):e1002223. PMID: 21901104; PMCID: PMC3161906.
      Citations: 15     Fields:    Translation:Cells
    36. Fonville NC, Vaksman Z, DeNapoli J, Hastings PJ, Rosenberg SM. Pathways of resistance to thymineless death in Escherichia coli and the function of UvrD. Genetics. 2011 Sep; 189(1):23-36. PMID: 21705756; PMCID: PMC3176125.
      Citations: 14     Fields:    Translation:Cells
    37. Lin HC, Hastings PA. Evolution of a Neotropical marine fish lineage (Subfamily Chaenopsinae, Suborder Blennioidei) based on phylogenetic analysis of combined molecular and morphological data. Mol Phylogenet Evol. 2011 Aug; 60(2):236-48. PMID: 21550409.
      Citations:    
    38. Hastings PJ. Mechanisms of ectopic gene conversion. Genes (Basel). 2010 Nov 29; 1(3):427-39. PMID: 24000309; PMCID: PMC3758752.
      Citations: 20     Fields:    
    39. Frisch RL, Su Y, Thornton PC, Gibson JL, Rosenberg SM, Hastings PJ. Separate DNA Pol II- and Pol IV-dependent pathways of stress-induced mutation during double-strand-break repair in Escherichia coli are controlled by RpoS. J Bacteriol. 2010 Sep; 192(18):4694-700. PMID: 20639336; PMCID: PMC2937414.
      Citations: 27     Fields:    Translation:Cells
    40. Hastings PJ, Hersh MN, Thornton PC, Fonville NC, Slack A, Frisch RL, Ray MP, Harris RS, Leal SM, Rosenberg SM. Competition of Escherichia coli DNA polymerases I, II and III with DNA Pol IV in stressed cells. PLoS One. 2010 May 27; 5(5):e10862. PMID: 20523737; PMCID: PMC2877720.
      Citations: 31     Fields:    Translation:Cells
    41. Gibson JL, Lombardo MJ, Thornton PC, Hu KH, Galhardo RS, Beadle B, Habib A, Magner DB, Frost LS, Herman C, Hastings PJ, Rosenberg SM. The sigma(E) stress response is required for stress-induced mutation and amplification in Escherichia coli. Mol Microbiol. 2010 Jul; 77(2):415-30. PMID: 20497332; PMCID: PMC2909356.
      Citations: 35     Fields:    Translation:Cells
    42. Fonville NC, Bates D, Hastings PJ, Hanawalt PC, Rosenberg SM. Role of RecA and the SOS response in thymineless death in Escherichia coli. PLoS Genet. 2010 Mar 05; 6(3):e1000865. PMID: 20221259; PMCID: PMC2832678.
      Citations: 34     Fields:    Translation:Cells
    43. Hastings PJ, Lupski JR, Rosenberg SM, Ira G. Mechanisms of change in gene copy number. Nat Rev Genet. 2009 Aug; 10(8):551-64. PMID: 19597530; PMCID: PMC2864001.
      Citations: 535     Fields:    Translation:Humans
    44. Galhardo RS, Do R, Yamada M, Friedberg EC, Hastings PJ, Nohmi T, Rosenberg SM. DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli. Genetics. 2009 May; 182(1):55-68. PMID: 19270270; PMCID: PMC2674841.
      Citations: 63     Fields:    Translation:Cells
    45. Hastings PJ, Ira G, Lupski JR. A microhomology-mediated break-induced replication model for the origin of human copy number variation. PLoS Genet. 2009 Jan; 5(1):e1000327. PMID: 19180184; PMCID: PMC2621351.
      Citations: 418     Fields:    Translation:HumansAnimalsCells
    46. Wu X, Strome ED, Meng Q, Hastings PJ, Plon SE, Kimmel M. A robust estimator of mutation rates. Mutat Res. 2009 Feb 10; 661(1-2):101-9. PMID: 19100753.
      Citations: 6     Fields:    Translation:AnimalsCells
    47. Gonzalez C, Hadany L, Ponder RG, Price M, Hastings PJ, Rosenberg SM. Mutability and importance of a hypermutable cell subpopulation that produces stress-induced mutants in Escherichia coli. PLoS Genet. 2008 Oct 03; 4(10):e1000208. PMID: 18833303; PMCID: PMC2543114.
      Citations: 32     Fields:    Translation:Cells
    48. Galhardo RS, Hastings PJ, Rosenberg SM. Mutation as a stress response and the regulation of evolvability. Crit Rev Biochem Mol Biol. 2007 Sep-Oct; 42(5):399-435. PMID: 17917874; PMCID: PMC3319127.
      Citations: 237     Fields:    Translation:HumansAnimalsCells
    49. Hastings PJ. Adaptive amplification. Crit Rev Biochem Mol Biol. 2007 Jul-Aug; 42(4):271-83. PMID: 17687669.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    50. Mukhopadhyay SS, Leung KS, Hicks MJ, Hastings PJ, Youssoufian H, Plon SE. Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia. J Cell Biol. 2006 Oct 23; 175(2):225-35. PMID: 17060495; PMCID: PMC2064564.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    51. Slack A, Thornton PC, Magner DB, Rosenberg SM, Hastings PJ. On the mechanism of gene amplification induced under stress in Escherichia coli. PLoS Genet. 2006 Apr; 2(4):e48. PMID: 16604155; PMCID: PMC1428787.
      Citations: 93     Fields:    Translation:Cells
    52. Lopez CR, Yang S, Deibler RW, Ray SA, Pennington JM, Digate RJ, Hastings PJ, Rosenberg SM, Zechiedrich EL. A role for topoisomerase III in a recombination pathway alternative to RuvABC. Mol Microbiol. 2005 Oct; 58(1):80-101. PMID: 16164551.
      Citations: 33     Fields:    Translation:Cells
    53. Hastings PJ, Slack A, Petrosino JF, Rosenberg SM. Adaptive amplification and point mutation are independent mechanisms: evidence for various stress-inducible mutation mechanisms. PLoS Biol. 2004 Dec; 2(12):e399. PMID: 15550983; PMCID: PMC529313.
      Citations: 45     Fields:    Translation:Cells
    54. Hastings PJ, Rosenberg SM, Slack A. Antibiotic-induced lateral transfer of antibiotic resistance. Trends Microbiol. 2004 Sep; 12(9):401-4. PMID: 15337159.
      Citations: 54     Fields:    Translation:Cells
    55. Rosenberg SM, Hastings PJ. Genomes: worming into genetic instability. Nature. 2004 Aug 05; 430(7000):625-6. PMID: 15295584.
      Citations: 4     Fields:    Translation:AnimalsCells
    56. Rosenberg SM, Hastings PJ. Adaptive point mutation and adaptive amplification pathways in the Escherichia coli Lac system: stress responses producing genetic change. J Bacteriol. 2004 Aug; 186(15):4838-43. PMID: 15262914; PMCID: PMC451650.
      Citations: 27     Fields:    Translation:Cells
    57. Rosenberg SM, Hastings PJ. Rebuttal: adaptive mutation in Escherichia coli (Foster). J Bacteriol. 2004 Aug; 186(15):4853. PMID: 15262918; PMCID: PMC451651.
      Citations: 1     Fields:    Translation:Cells
    58. Rosenberg SM, Hastings PJ. Rebuttal: growth under selection stimulates Lac(+) reversion (Roth and Andersson). J Bacteriol. 2004 Aug; 186(15):4862-3. PMID: 15262922; PMCID: PMC451652.
      Citations: 3     Fields:    Translation:Cells
    59. Hersh MN, Ponder RG, Hastings PJ, Rosenberg SM. Adaptive mutation and amplification in Escherichia coli: two pathways of genome adaptation under stress. Res Microbiol. 2004 Jun; 155(5):352-9. PMID: 15207867.
      Citations: 40     Fields:    Translation:Cells
    60. Rosenberg SM, Hastings PJ. Microbiology and evolution. Modulating mutation rates in the wild. Science. 2003 May 30; 300(5624):1382-3. PMID: 12775830.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    61. Hastings PJ, Rosenberg SM. In pursuit of a molecular mechanism for adaptive gene amplification. DNA Repair (Amst). 2002 Feb 28; 1(2):111-23. PMID: 12509258.
      Citations: 7     Fields:    Translation:Cells
    62. McKenzie GJ, Lee PL, Lombardo MJ, Hastings PJ, Rosenberg SM. SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification. Mol Cell. 2001 Mar; 7(3):571-9. PMID: 11463382.
      Citations: 129     Fields:    Translation:Cells
    63. Hastings PJ, Bull HJ, Klump JR, Rosenberg SM. Adaptive amplification: an inducible chromosomal instability mechanism. Cell. 2000 Nov 22; 103(5):723-31. PMID: 11114329.
      Citations: 70     Fields:    Translation:Cells
    64. Bull HJ, McKenzie GJ, Hastings PJ, Rosenberg SM. Evidence that stationary-phase hypermutation in the Escherichia coli chromosome is promoted by recombination. Genetics. 2000 Apr; 154(4):1427-37. PMID: 10747042; PMCID: PMC1461015.
      Citations: 26     Fields:    Translation:Cells
    65. Harris RS, Feng G, Ross KJ, Sidhu R, Thulin C, Longerich S, Szigety SK, Hastings PJ, Winkler ME, Rosenberg SM. Mismatch repair is diminished during stationary-phase mutation. Mutat Res. 1999 Jul; 437(1):51-60. PMID: 10425389.
      Citations: 26     Fields:    Translation:Cells
    66. Reiter LT, Hastings PJ, Nelis E, De Jonghe P, Van Broeckhoven C, Lupski JR. Human meiotic recombination products revealed by sequencing a hotspot for homologous strand exchange in multiple HNPP deletion patients. Am J Hum Genet. 1998 May; 62(5):1023-33. PMID: 9545397; PMCID: PMC1377084.
      Citations: 55     Fields:    Translation:HumansCells
    67. Manivasakam P, Rosenberg SM, Hastings PJ. Poorly repaired mismatches in heteroduplex DNA are hyper-recombinagenic in Saccharomyces cerevisiae. Genetics. 1996 Feb; 142(2):407-16. PMID: 8852840; PMCID: PMC1206975.
      Citations: 8     Fields:    Translation:AnimalsCells
    68. Hastings PJ, McGill C, Shafer B, Strathern JN. Ends-in vs. ends-out recombination in yeast. Genetics. 1993 Dec; 135(4):973-80. PMID: 8307337; PMCID: PMC1205758.
      Citations: 36     Fields:    Translation:AnimalsCells
    69. Hastings PJ. Mechanism and control of recombination in fungi. Mutat Res. 1992 Dec 01; 284(1):97-110. PMID: 1279396.
      Citations: 3     Fields:    Translation:AnimalsCells
    70. Rosenberg SM, Hastings PJ. The split-end model for homologous recombination at double-strand breaks and at Chi. Biochimie. 1991 Apr; 73(4):385-97. PMID: 1911939.
      Citations: 39     Fields:    Translation:Cells
    71. Hastings PJ. Recombination in the eukaryotic nucleus. Bioessays. 1988 Aug-Sep; 9(2-3):61-4. PMID: 3066359.
      Citations: 25     Fields:    Translation:Cells
    72. Hastings PJ, Savage EA. Further evidence of a disparity between conversion and restoration in the his1 locus of Saccharomyces cerevisiae. Curr Genet. 1984 Jan; 8(1):23-8. PMID: 24177525.
      Citations:    Fields:    
    73. Savage EA, Hastings PJ. Marker effects and the nature of the recombination event at the his1 locus of Saccharomyces cerevisiae. Curr Genet. 1981 Apr; 3(1):37-47. PMID: 24189951.
      Citations: 6     Fields:    
    74. Hastings PJ, Kalogeropoulos A, Rossignol JL. Restoration to the parental genotype of mismatches formed in recombinant DNA heteroduplex. Curr Genet. 1980 Oct; 2(2):169-74. PMID: 24189808.
      Citations: 5     Fields:    
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