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KAZUHIRO OKA

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Endocrinology


    Collapse Research 
    Collapse research activities and funding
    R01HL073144     (OKA, KAZUHIRO)Jul 1, 2003 - Jun 30, 2008
    NIH
    Novel Gene Therapy using Helper-Dependent Adenovirus
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ohashi K, Matsue Y, Maeda D, Fujimoto Y, Kagiyama N, Sunayama T, Dotare T, Jujo K, Saito K, Kamiya K, Saito H, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Wada H, Hiki M, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Wakaume K, Oka K, Momomura SI, Minamino T, Ohashi K, Matsue Y, Maeda D, Fujimoto Y, Kagiyama N, Sunayama T, Dotare T, Saito K, Kamiya K, Ogasahara Y, Maekawa E, Kitai T, Hiki M, Kasai T, Oka K, Minamino T. Impact of Multidomain Frailty on the Mode of Death in Older Patients With Heart Failure: A Cohort Study. Circ Cardiovasc Qual Outcomes. 2024 May; 17(5):e010416. PMID: 38529634.
      Citations: 1     Fields:    Translation:Humans
    2. Kulkarni AA, Seal AG, Sonnet C, Oka K. Streamlined Adeno-Associated Virus Production Using Suspension HEK293T Cells. Bio Protoc. 2024 Feb 05; 14(3):e4931. PMID: 38379831; PMCID: PMC10875358.
      Citations:    
    3. Henrickson A, Ding X, Seal AG, Qu Z, Tomlinson L, Forsey J, Gradinaru V, Oka K, Demeler B. Characterization and quantification of adeno-associated virus capsid-loading states by multi-wavelength analytical ultracentrifugation with UltraScan. Nanomedicine (Lond). 2023 09; 18(22):1519-1534. PMID: 37877696; PMCID: PMC10652292.
      Citations:    Fields:    Translation:Cells
    4. Maeda D, Matsue Y, Kagiyama N, Jujo K, Saito K, Kamiya K, Saito H, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Wada H, Hiki M, Dotare T, Sunayama T, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Wakaume K, Oka K, Momomura SI, Minamino T. Sex differences in the prevalence and prognostic impact of physical frailty and sarcopenia among older patients with heart failure. Nutr Metab Cardiovasc Dis. 2022 Feb; 32(2):365-372. PMID: 34893406.
      Citations:    Fields:    Translation:Humans
    5. Deng S, Oka K. Adeno-Associated Virus as Gene Delivery Vehicle into the Retina. Methods Mol Biol. 2020; 2092:77-90. PMID: 31786783.
      Citations: 1     Fields:    Translation:HumansCells
    6. Ogawa N, Terashima T, Oka K, Chan L, Kojima H. Gene therapy for neuropathic pain using dorsal root ganglion-targeted helper-dependent adenoviral vectors with GAD67 expression. Pain Rep. 2018 Nov; 3(6):e695. PMID: 30706038; PMCID: PMC6344132.
      Citations: 4     
    7. Ito A, Hong C, Oka K, Salazar JV, Diehl C, Witztum JL, Bensinger SJ, Chan L, Tontonoz P, Diaz M, Castrillo A. Cholesterol Accumulation in CD11c+ Immune Cells Is a Causal and Targetable Factor in Autoimmune Disease. Immunity. 2016 12 20; 45(6):1311-1326. PMID: 28002731; PMCID: PMC5181791.
      Citations: 43     Fields:    Translation:AnimalsCells
    8. Chen Q, Takahashi Y, Oka K, Ma JX. Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling. Mol Cell Biol. 2016 10 15; 36(20):2645-54. PMID: 27528615; PMCID: PMC5038150.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    9. Son SH, Goo YH, Choi M, Saha PK, Oka K, Chan LC, Paul A. Enhanced atheroprotection and lesion remodelling by targeting the foam cell and increasing plasma cholesterol acceptors. Cardiovasc Res. 2016 Feb 01; 109(2):294-304. PMID: 26487692; PMCID: PMC4724936.
      Citations: 13     Fields:    Translation:AnimalsCells
    10. Li R, Buras E, Lee J, Liu R, Liu V, Espiritu C, Ozer K, Thompson B, Nally L, Yuan G, Oka K, Chang B, Samson S, Yechoor V, Chan L. Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice. Gene Ther. 2015 Nov; 22(11):876-82. PMID: 26172077; PMCID: PMC4636470.
      Citations: 5     Fields:    Translation:AnimalsCells
    11. Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. Erratum. PD-L1-Driven Tolerance Protects Neurogenin3-Induced Islet Neogenesis to Reverse Established Type 1 Diabetes in NOD Mice. Diabetes 2015;64:529-540. Diabetes. 2015 Jul; 64(7):2685. PMID: 26106199; PMCID: PMC4877680.
      Citations:    Fields:    
    12. Willecke F, Yuan C, Oka K, Chan L, Hu Y, Barnhart S, Bornfeldt KE, Goldberg IJ, Fisher EA. Effects of High Fat Feeding and Diabetes on Regression of Atherosclerosis Induced by Low-Density Lipoprotein Receptor Gene Therapy in LDL Receptor-Deficient Mice. PLoS One. 2015; 10(6):e0128996. PMID: 26046657; PMCID: PMC4457481.
      Citations: 21     Fields:    Translation:AnimalsCells
    13. Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice. Diabetes. 2015 Feb; 64(2):529-40. PMID: 25332429; PMCID: PMC4303975.
      Citations: 11     Fields:    Translation:AnimalsCells
    14. Oka K, Mullins CE, Kushwaha RS, Leen AM, Chan L. Gene therapy for rhesus monkeys heterozygous for LDL receptor deficiency by balloon catheter hepatic delivery of helper-dependent adenoviral vector. Gene Ther. 2015 Jan; 22(1):87-95. PMID: 25231173; PMCID: PMC4289097.
      Citations: 7     Fields:    Translation:AnimalsCells
    15. Hopkins J, Hwang G, Jacob J, Sapp N, Bedigian R, Oka K, Overbeek P, Murray S, Jordan PW. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet. 2014 Jul; 10(7):e1004413. PMID: 24992337; PMCID: PMC4081007.
      Citations: 60     Fields:    Translation:AnimalsCells
    16. Ogawa N, Kawai H, Terashima T, Kojima H, Oka K, Chan L, Maegawa H. Gene therapy for neuropathic pain by silencing of TNF-a expression with lentiviral vectors targeting the dorsal root ganglion in mice. PLoS One. 2014; 9(3):e92073. PMID: 24642694; PMCID: PMC3958473.
      Citations: 27     Fields:    Translation:AnimalsCells
    17. Caburet S, Arboleda VA, Llano E, Overbeek PA, Barbero JL, Oka K, Harrison W, Vaiman D, Ben-Neriah Z, Garc?a-Tu??n I, Fellous M, Pend?s AM, Veitia RA, Vilain E. Mutant cohesin in premature ovarian failure. N Engl J Med. 2014 Mar 06; 370(10):943-949. PMID: 24597867; PMCID: PMC4068824.
      Citations: 101     Fields:    Translation:HumansAnimals
    18. Urabe H, Kojima H, Chan L, Terashima T, Ogawa N, Katagi M, Fujino K, Kumagai A, Kawai H, Asakawa A, Inui A, Yasuda H, Eguchi Y, Oka K, Maegawa H, Kashiwagi A, Kimura H. Haematopoietic cells produce BDNF and regulate appetite upon migration to the hypothalamus. Nat Commun. 2013; 4:1526. PMID: 23443554; PMCID: PMC3640364.
      Citations: 8     Fields:    Translation:AnimalsCells
    19. Li R, Oka K, Yechoor V. Neo-islet formation in liver of diabetic mice by helper-dependent adenoviral vector-mediated gene transfer. J Vis Exp. 2012 Oct 10; (68). PMID: 23093064; PMCID: PMC3490299.
      Citations:    Fields:    Translation:AnimalsCells
    20. Poungvarin N, Lee JK, Yechoor VK, Li MV, Assavapokee T, Suksaranjit P, Thepsongwajja JJ, Saha PK, Oka K, Chan L. Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity. Diabetologia. 2012 Jun; 55(6):1783-96. PMID: 22382520; PMCID: PMC4010252.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    21. Ali YO, Zhu J, Wu CS, Oka K, Zhai RG, Lu HC, Ljungberg MC. CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy. Hum Mol Genet. 2012 Jan 15; 21(2):251-67. PMID: 22027994; PMCID: PMC3276285.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    22. Li R, Chao H, Ko KW, Cormier S, Dieker C, Nour EA, Wang S, Chan L, Oka K. Gene Therapy Targeting LDL Cholesterol but not HDL Cholesterol Induces Regression of Advanced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia. J Genet Syndr Gene Ther. 2011 Sep 28; 2:106. PMID: 23106034; PMCID: PMC3480198.
      Citations: 13     
    23. Li R, Paul A, Ko KW, Sheldon M, Rich BE, Terashima T, Dieker C, Cormier S, Li L, Nour EA, Chan L, Oka K. Interleukin-7 induces recruitment of monocytes/macrophages to endothelium. Eur Heart J. 2012 Dec; 33(24):3114-23. PMID: 21804111; PMCID: PMC3598429.
      Citations: 22     Fields:    Translation:AnimalsCells
    24. Hu Y, Ren X, Wang H, Ma Y, Wang L, Shen Y, Oka K, Zhang Z, Zhang Y. Liver-specific expression of an exogenous gene controlled by human apolipoprotein A-I promoter. Int J Pharm. 2010 Oct 15; 398(1-2):161-4. PMID: 20656001.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    25. Moulik M, Vatta M, Witt SH, Arola AM, Murphy RT, McKenna WJ, Boriek AM, Oka K, Labeit S, Bowles NE, Arimura T, Kimura A, Towbin JA. ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene. J Am Coll Cardiol. 2009 Jul 21; 54(4):325-33. PMID: 19608030; PMCID: PMC2915893.
      Citations: 60     Fields:    Translation:HumansCells
    26. Terashima T, Oka K, Kritz AB, Kojima H, Baker AH, Chan L. DRG-targeted helper-dependent adenoviruses mediate selective gene delivery for therapeutic rescue of sensory neuronopathies in mice. J Clin Invest. 2009 Jul; 119(7):2100-112. PMID: 19603551; PMCID: PMC2701884.
      Citations: 20     Fields:    Translation:AnimalsCells
    27. Sakai K, Tiebel O, Ljungberg MC, Sullivan M, Lee HJ, Terashima T, Li R, Kobayashi K, Lu HC, Chan L, Oka K. A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins. Brain Res. 2009 Jun 18; 1276:11-21. PMID: 19393635; PMCID: PMC2733343.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    28. Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Chan L, Oka K, Thomas MJ, Sorci-Thomas MG. Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity. Arterioscler Thromb Vasc Biol. 2009 Jun; 29(6):843-9. PMID: 19286630; PMCID: PMC2761013.
      Citations: 62     Fields:    Translation:AnimalsCells
    29. Yechoor V, Liu V, Espiritu C, Paul A, Oka K, Kojima H, Chan L. Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes. Dev Cell. 2009 Mar; 16(3):358-73. PMID: 19289082; PMCID: PMC2676438.
      Citations: 86     Fields:    Translation:AnimalsCells
    30. Samson SL, Gonzalez EV, Yechoor V, Bajaj M, Oka K, Chan L. Gene therapy for diabetes: metabolic effects of helper-dependent adenoviral exendin 4 expression in a diet-induced obesity mouse model. Mol Ther. 2008 11; 16(11):1805-12. PMID: 18781141; PMCID: PMC2582376.
      Citations: 18     Fields:    Translation:AnimalsCells
    31. Johansson F, Kramer F, Barnhart S, Kanter JE, Vaisar T, Merrill RD, Geng L, Oka K, Chan L, Chait A, Heinecke JW, Bornfeldt KE. Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):2082-7. PMID: 18252823; PMCID: PMC2538884.
      Citations: 53     Fields:    Translation:AnimalsCells
    32. Oka K, Belalcazar LM, Dieker C, Nour EA, Nuno-Gonzalez P, Paul A, Cormier S, Shin JK, Finegold M, Chan L. Sustained phenotypic correction in a mouse model of hypoalphalipoproteinemia with a helper-dependent adenovirus vector. Gene Ther. 2007 Feb; 14(3):191-202. PMID: 16957769; PMCID: PMC1780075.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    33. MacDougall ED, Kramer F, Polinsky P, Barnhart S, Askari B, Johansson F, Varon R, Rosenfeld ME, Oka K, Chan L, Schwartz SM, Bornfeldt KE. Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficient mice. Am J Pathol. 2006 Jun; 168(6):2064-73. PMID: 16723719; PMCID: PMC1606621.
      Citations: 20     Fields:    Translation:AnimalsCells
    34. Johnson JL, Baker AH, Oka K, Chan L, Newby AC, Jackson CL, George SJ. Suppression of atherosclerotic plaque progression and instability by tissue inhibitor of metalloproteinase-2: involvement of macrophage migration and apoptosis. Circulation. 2006 May 23; 113(20):2435-44. PMID: 16702468.
      Citations: 49     Fields:    Translation:AnimalsCells
    35. Wang W, Huang XR, Canlas E, Oka K, Truong LD, Deng C, Bhowmick NA, Ju W, Bottinger EP, Lan HY. Essential role of Smad3 in angiotensin II-induced vascular fibrosis. Circ Res. 2006 Apr 28; 98(8):1032-9. PMID: 16556868; PMCID: PMC1450325.
      Citations: 91     Fields:    Translation:HumansCells
    36. Oka K, Chan L. Helper-dependent adenoviral vectors. Curr Protoc Hum Genet. 2005 Nov; Chapter 12:Unit 12.13. PMID: 18428374.
      Citations: 1     Fields:    Translation:HumansCells
    37. Schillinger KJ, Tsai SY, Taffet GE, Reddy AK, Marian AJ, Entman ML, Oka K, Chan L, O'Malley BW. Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13789-94. PMID: 16162668; PMCID: PMC1236585.
      Citations: 22     Fields:    Translation:AnimalsCells
    38. Nuno-Gonzalez P, Chao H, Oka K. Targeting site-specific chromosome integration. Acta Biochim Pol. 2005; 52(2):285-91. PMID: 15940345; PMCID: PMC1360607.
      Citations:    Fields:    Translation:HumansAnimalsCells
    39. Oka K, Chan L. Inhibition and regression of atherosclerotic lesions. Acta Biochim Pol. 2005; 52(2):311-9. PMID: 15940346; PMCID: PMC1360606.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    40. Oka K, Chan L. Helper-dependent adenoviral vectors. Curr Protoc Mol Biol. 2005 Feb; Chapter 16:Unit 16.24. PMID: 18265354.
      Citations:    Fields:    Translation:Cells
    41. Oka K, Chan L. Construction and characterization of helper-dependent adenoviral vectors for sustained in vivo gene therapy. Methods Mol Med. 2005; 108:329-50. PMID: 16028693.
      Citations: 2     Fields:    Translation:HumansCells
    42. Nomura S, Merched A, Nour E, Dieker C, Oka K, Chan L. Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia. Gene Ther. 2004 Oct; 11(20):1540-8. PMID: 15269711.
      Citations:    
    43. Oka K, Chan L. Liver-directed gene therapy for dyslipidemia and diabetes. Curr Atheroscler Rep. 2004 May; 6(3):203-9. PMID: 15068745; PMCID: PMC1224746.
      Citations: 3     Fields:    Translation:Humans
    44. Pastore L, Belalcazar LM, Oka K, Cela R, Lee B, Chan L, Beaudet AL. Helper-dependent adenoviral vector-mediated long-term expression of human apolipoprotein A-I reduces atherosclerosis in apo E-deficient mice. Gene. 2004 Mar 03; 327(2):153-60. PMID: 14980712.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    45. Belalcazar LM, Merched A, Carr B, Oka K, Chen KH, Pastore L, Beaudet A, Chan L. Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia. Circulation. 2003 Jun 03; 107(21):2726-32. PMID: 12742997.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    46. Oka K, Chan L. Recent advances in liver-directed gene therapy for dyslipidemia. Curr Atheroscler Rep. 2002 May; 4(3):199-207. PMID: 11931717.
      Citations: 3     Fields:    Translation:Humans
    47. Kim IH, Piedra PA, Oka K, Chan L, J?zkowicz A. Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector. Proc Natl Acad Sci U S A. 2001 Nov 06; 98(23):13282-7. PMID: 11687662; PMCID: PMC60862.
      Citations: 84     Fields:    Translation:AnimalsCells
    48. Oka K, Pastore L, Kim IH, Merched A, Nomura S, Lee HJ, Merched-Sauvage M, Arden-Riley C, Lee B, Finegold M, Beaudet A, Chan L. Long-term stable correction of low-density lipoprotein receptor-deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor. Circulation. 2001 Mar 06; 103(9):1274-81. PMID: 11238273.
      Citations: 42     Fields:    Translation:AnimalsCells
    49. Oka K, Davis AR, Chan L. Recent advances in liver-directed gene therapy: implications for the treatment of dyslipidemia. Curr Opin Lipidol. 2000 Apr; 11(2):179-86. PMID: 10787180.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    50. Chan L, Chang BH, Liao W, Oka K, Lau PP. Apolipoprotein B: from editosome to proteasome. Recent Prog Horm Res. 2000; 55:93-125; discussion 126. PMID: 11036935.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    51. Kobayashi K, Forte TM, Taniguchi S, Ishida BY, Oka K, Chan L. The db/db mouse, a model for diabetic dyslipidemia: molecular characterization and effects of Western diet feeding. Metabolism. 2000 Jan; 49(1):22-31. PMID: 10647060.
      Citations: 101     Fields:    Translation:Animals
    52. Tiebel O, Oka K, Robinson K, Sullivan M, Martinez J, Nakamuta M, Ishimura-Oka K, Chan L. Mouse very low-density lipoprotein receptor (VLDLR): gene structure, tissue-specific expression and dietary and developmental regulation. Atherosclerosis. 1999 Aug; 145(2):239-51. PMID: 10488949.
      Citations: 26     Fields:    Translation:AnimalsCells
    53. Yeung SC, Anderson J, Kobayashi K, Oka K, Chan L. Production of rabbit polyclonal antibody against apobec-1 by genetic immunization. J Lipid Res. 1997 Dec; 38(12):2627-32. PMID: 9458285.
      Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
    54. Gouni-Berthold I, Oka K, Berthold HK, Chan L. Failure of the nonselective beta-blocker propranolol to affect lipoprotein lipase gene expression in the rat. Lipids. 1997 Sep; 32(9):943-7. PMID: 9307934.
      Citations: 1     Fields:    Translation:AnimalsCells
    55. Oka K, Kobayashi K, Sullivan M, Martinez J, Teng BB, Ishimura-Oka K, Chan L. Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased low density lipoprotein in mice. J Biol Chem. 1997 Jan 17; 272(3):1456-60. PMID: 8999814.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    56. Oka K, Ishimura-Oka K, Chu MJ, Chan L. Transcription of the human hepatic lipase gene is modulated by multiple negative elements in HepG2 cells. Gene. 1996 Nov 21; 180(1-2):69-80. PMID: 8973349.
      Citations: 4     Fields:    Translation:HumansCells
    57. Nakamuta M, Chang BH, Zsigmond E, Kobayashi K, Lei H, Ishida BY, Oka K, Li E, Chan L. Complete phenotypic characterization of apobec-1 knockout mice with a wild-type genetic background and a human apolipoprotein B transgenic background, and restoration of apolipoprotein B mRNA editing by somatic gene transfer of Apobec-1. J Biol Chem. 1996 Oct 18; 271(42):25981-8. PMID: 8824235.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    58. Kobayashi K, Oka K, Forte T, Ishida B, Teng B, Ishimura-Oka K, Nakamuta M, Chan L. Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor. J Biol Chem. 1996 Mar 22; 271(12):6852-60. PMID: 8636110.
      Citations: 31     Fields:    Translation:AnimalsCells
    59. Uelmen PJ, Oka K, Sullivan M, Chang CC, Chang TY, Chan L. Tissue-specific expression and cholesterol regulation of acylcoenzyme A:cholesterol acyltransferase (ACAT) in mice. Molecular cloning of mouse ACAT cDNA, chromosomal localization, and regulation of ACAT in vivo and in vitro. J Biol Chem. 1995 Nov 03; 270(44):26192-201. PMID: 7592824.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    60. Ishimura-Oka K, Nakamuta M, Chu MJ, Sullivan M, Chan L, Oka K. Partial structure of the mouse glucokinase gene. Genomics. 1995 Oct 10; 29(3):751-4. PMID: 8575769.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    61. Nakamuta M, Oka K, Krushkal J, Kobayashi K, Yamamoto M, Li WH, Chan L. Alternative mRNA splicing and differential promoter utilization determine tissue-specific expression of the apolipoprotein B mRNA-editing protein (Apobec1) gene in mice. Structure and evolution of Apobec1 and related nucleoside/nucleotide deaminases. J Biol Chem. 1995 Jun 02; 270(22):13042-56. PMID: 7768898.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    62. Oka K, Ishimura-Oka K, Chu MJ, Sullivan M, Krushkal J, Li WH, Chan L. Mouse very-low-density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density-lipoprotein receptor. Eur J Biochem. 1994 Sep 15; 224(3):975-82. PMID: 7925422.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    63. Tzung KW, Ishimura-Oka K, Kihara S, Oka K, Chan L. Structure of the mouse cholesterol 7 alpha-hydroxylase gene. Genomics. 1994 May 01; 21(1):244-7. PMID: 8088795.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    64. Oka K, Tzung KW, Sullivan M, Lindsay E, Baldini A, Chan L. Human very-low-density lipoprotein receptor complementary DNA and deduced amino acid sequence and localization of its gene (VLDLR) to chromosome band 9p24 by fluorescence in situ hybridization. Genomics. 1994 Mar 15; 20(2):298-300. PMID: 8020981.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    65. Oka K. [Structure and regulation of hepatic lipase]. Seikagaku. 1993 Dec; 65(12):1516-21. PMID: 8308397.
      Citations:    Fields:    Translation:HumansAnimalsCells
    66. Kihara S, Wölle J, Ehnholm C, Chan L, Oka K, W?lle J. Regulation of hepatic triglyceride lipase by thyroid hormone in HepG2 cells. J Lipid Res. 1993 Jun; 34(6):961-70. PMID: 8354961.
      Citations: 7     Fields:    Translation:HumansCells
    67. Gouni I, Oka K, Etienne J, Chan L. Endotoxin-induced hypertriglyceridemia is mediated by suppression of lipoprotein lipase at a post-transcriptional level. J Lipid Res. 1993 Jan; 34(1):139-46. PMID: 8445338.
      Citations: 18     Fields:    Translation:AnimalsCells
    68. Ishimura-Oka K, Faustinella F, Kihara S, Smith LC, Oka K, Chan L. A missense mutation (Trp86----Arg) in exon 3 of the lipoprotein lipase gene: a cause of familial chylomicronemia. Am J Hum Genet. 1992 Jun; 50(6):1275-80. PMID: 1598907; PMCID: PMC1682574.
      Citations: 3     Fields:    Translation:HumansCells
    69. Ishimura-Oka K, Semenkovich CF, Faustinella F, Goldberg IJ, Shachter N, Smith LC, Coleman T, Hide WA, Brown WV, Oka K, et al. A missense (Asp250----Asn) mutation in the lipoprotein lipase gene in two unrelated families with familial lipoprotein lipase deficiency. J Lipid Res. 1992 May; 33(5):745-54. PMID: 1619366.
      Citations: 5     Fields:    Translation:HumansCells
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