InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    R01HD098059     (HAN, SANG JUN JUN)Mar 6, 2020 - Dec 31, 2024
    The Genomic Function of Estrogen Receptor Beta in Endometriosis
    Role: Principal Investigator

    U24 DK097748     (Bert W. O'Malley)Sep 1, 2015 - Aug 31, 2018
    Identification of Nuclear Receptor Genomic Network that Links Endometriosis to Birth Defects
    Role: Pilot Project PI

    R01 HD082786     (Bert W. O'Malley)Apr 1, 2014 - Mar 31, 2020
    The ERbeta/SRC-1 isoform complex drives endometriosis progression
    Role: Co-PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Han SJ, Sung N, Wang J, O'Malley BW, Lonard DM. Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment. Breast Cancer Res. 2022 10 31; 24(1):73. PMID: 36316775; PMCID: PMC9620627.
      Citations: 2     Fields:    Translation:AnimalsCells
    2. Gilad Y, Eliaz Y, Yu Y, Dean AM, Han SJ, Qin L, O'Malley BW, Lonard DM. A genome-scale CRISPR Cas9 dropout screen identifies synthetically lethal targets in SRC-3 inhibited cancer cells. Commun Biol. 2021 03 25; 4(1):399. PMID: 33767353; PMCID: PMC7994904.
      Citations:    Translation:HumansCells
    3. Mohankumar K, Li X, Sung N, Cho YJ, Han SJ, Safe S. Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis. Endocrinology. 2020 04 01; 161(4). PMID: 32099996; PMCID: PMC7105386.
      Citations: 2     Fields:    Translation:Animals
    4. Han SJ, Lee JE, Cho YJ, Park MJ, O'Malley BW. Genomic Function of Estrogen Receptor ? in Endometriosis. Endocrinology. 2019 11 01; 160(11):2495-2516. PMID: 31504401; PMCID: PMC6773435.
      Citations: 12     Fields:    Translation:HumansAnimals
    5. Gilad Y, Eliaz Y, Yu Y, Han SJ, O'Malley BW, Lonard DM. Drug-induced PD-L1 expression and cell stress response in breast cancer cells can be balanced by drug combination. Sci Rep. 2019 10 22; 9(1):15099. PMID: 31641154; PMCID: PMC6805932.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    6. Cho YJ, Lee JE, Park MJ, O'Malley BW, Han SJ. Bufalin suppresses endometriosis progression by inducing pyroptosis and apoptosis. J Endocrinol. 2018 06; 237(3):255-269. PMID: 29636364; PMCID: PMC5943165.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    7. Cho YJ, Lee SH, Park JW, Han M, Park MJ, Han SJ. Dysfunctional signaling underlying endometriosis: current state of knowledge. J Mol Endocrinol. 2018 04; 60(3):R97-R113. PMID: 29330150.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    8. Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor ? Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74. PMID: 26544941; PMCID: PMC4640214.
      Citations: 100     Fields:    Translation:HumansAnimals
    9. Han SJ, Begum K, Foulds CE, Hamilton RA, Bailey S, Malovannaya A, Chan D, Qin J, O'Malley BW. The Dual Estrogen Receptor a Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety. Mol Pharmacol. 2016 Jan; 89(1):14-26. PMID: 26487511; PMCID: PMC4702103.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    10. Han SJ, O'Malley BW. The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis. Hum Reprod Update. 2014 Jul-Aug; 20(4):467-84. PMID: 24634322; PMCID: PMC4063700.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    11. Han SJ, Hawkins SM, Begum K, Jung SY, Kovanci E, Qin J, Lydon JP, DeMayo FJ, O'Malley BW. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med. 2012 Jul; 18(7):1102-11. PMID: 22660634; PMCID: PMC3541027.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    12. Zhang L, Zhang B, Han SJ, Shore AN, Rosen JM, Demayo FJ, Xin L. Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis. Transgenic Res. 2012 Oct; 21(5):1117-23. PMID: 22350718; PMCID: PMC3433578.
      Citations: 13     Fields:    Translation:AnimalsCells
    13. Han SJ, DeMayo FJ, O'Malley BW. Dynamic regulation of progesterone receptor activity in female reproductive tissues. Ernst Schering Found Symp Proc. 2007; (1):25-43. PMID: 18543433.
      Citations: 5     Fields:    Translation:HumansAnimals
    14. Kang JS, Kim SH, Hwang MS, Han SJ, Lee YC, Kim YJ. The structural and functional organization of the yeast mediator complex. J Biol Chem. 2001 Nov 09; 276(45):42003-10. PMID: 11555651.
      Citations: 69     Fields:    Translation:AnimalsCells
    15. Han SJ, Lee JS, Kang JS, Kim YJ. Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem. 2001 Oct 05; 276(40):37020-6. PMID: 11470794.
      Citations: 19     Fields:    Translation:AnimalsCells
    16. Park JM, Kim HS, Han SJ, Hwang MS, Lee YC, Kim YJ. In vivo requirement of activator-specific binding targets of mediator. Mol Cell Biol. 2000 Dec; 20(23):8709-19. PMID: 11073972; PMCID: PMC86488.
      Citations: 60     Fields:    Translation:AnimalsCells
    17. Kwon JY, Park JM, Gim BS, Han SJ, Lee J, Kim YJ. Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14990-5. PMID: 10611325; PMCID: PMC24760.
      Citations: 19     Fields:    Translation:AnimalsCells
    18. Lee YC, Park JM, Min S, Han SJ, Kim YJ. An activator binding module of yeast RNA polymerase II holoenzyme. Mol Cell Biol. 1999 Apr; 19(4):2967-76. PMID: 10082564; PMCID: PMC84091.
      Citations: 72     Fields:    Translation:AnimalsCells
    19. Han SJ, Lee YC, Gim BS, Ryu GH, Park SJ, Lane WS, Kim YJ. Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation. Mol Cell Biol. 1999 Feb; 19(2):979-88. PMID: 9891034; PMCID: PMC116029.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    20. Han SJ, Lee BJ, Kang HS. Purification and characterization of the nuclear ribonuclease P of Aspergillus nidulans. Eur J Biochem. 1998 Jan 15; 251(1-2):244-51. PMID: 9492290.
      Citations: 4     Fields:    Translation:AnimalsCells
    21. Han SJ, Kang HS. Purification and characterization of the precursor tRNA 3'-end processing nuclease from Aspergillus nidulans. Biochem Biophys Res Commun. 1997 Apr 17; 233(2):354-8. PMID: 9144538.
      Citations: 6     Fields:    Translation:AnimalsCells
    22. Han SJ, Yoo YJ, Kang HS. Characterization of a bifunctional cellulase and its structural gene. The cell gene of Bacillus sp. D04 has exo- and endoglucanase activity. J Biol Chem. 1995 Oct 27; 270(43):26012-9. PMID: 7592793.
      Citations: 13     Fields:    Translation:Cells
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