LISA WANG

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Biography 
    Collapse education and training
    Washington University, St. LouisA.B.1988Biology
    University of North Carolina, Chapel HillM.D.1993Medicine

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    R01AR059063     (WANG, LISA L)Apr 1, 2010 - Mar 31, 2015
    NIH
    The Role of RECQL4 in Bone Development and Osteosarcoma
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Young EP, Cheng WS, Bernhardt MB, Wang LL, Rainusso N, Foster JH. Risk factors associated with delayed methotrexate clearance and increased toxicity in pediatric patients with osteosarcoma. Pediatr Blood Cancer. 2020 04; 67(4):e28123. PMID: 31867853.
      Citations:    Fields:    Translation:Humans
    2. Ajeawung NF, Nguyen TTM, Lu L, Kucharski TJ, Rousseau J, Molidperee S, Atienza J, Gamache I, Jin W, Plon SE, Lee BH, Teodoro JG, Wang LL, Campeau PM. Mutations in ANAPC1, Encoding a Scaffold Subunit of the Anaphase-Promoting Complex, Cause Rothmund-Thomson Syndrome Type 1. Am J Hum Genet. 2019 09 05; 105(3):625-630. PMID: 31303264.
      Citations: 3     Fields:    Translation:Humans
    3. Rainusso N, Cleveland H, Hernandez JA, Quintanilla NM, Hicks J, Vasudevan S, Marco RAW, Allen-Rhoades W, Wang LL, Yustein JT. Generation of patient-derived tumor xenografts from percutaneous tumor biopsies in children with bone sarcomas. Pediatr Blood Cancer. 2019 04; 66(4):e27579. PMID: 30548185.
      Citations: 4     Fields:    Translation:Humans
    4. Jewell BE, Liu M, Lu L, Zhou R, Tu J, Zhu D, Huo Z, Xu A, Wang D, Mata H, Jin W, Xia W, Rao PH, Zhao R, Hung MC, Wang LL, Lee DF. Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation. Stem Cell Res. 2018 12; 33:36-40. PMID: 30312871.
      Citations:    Fields:    Translation:HumansCells
    5. Cao F, Lu L, Abrams SA, Hawthorne KM, Tam A, Jin W, Dawson B, Shypailo R, Liu H, Lee B, Nagamani SCS, Wang LL. Generalized metabolic bone disease and fracture risk in Rothmund-Thomson syndrome. Hum Mol Genet. 2017 08 15; 26(16):3046-3055. PMID: 28486640.
      Citations: 4     Fields:    Translation:HumansAnimals
    6. Lin YH, Jewell BE, Gingold J, Lu L, Zhao R, Wang LL, Lee DF. Osteosarcoma: Molecular Pathogenesis and iPSC Modeling. Trends Mol Med. 2017 08; 23(8):737-755. PMID: 28735817.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    7. Walsh MF, Chang VY, Kohlmann WK, Scott HS, Cunniff C, Bourdeaut F, Molenaar JJ, Porter CC, Sandlund JT, Plon SE, Wang LL, Savage SA. Recommendations for Childhood Cancer Screening and Surveillance in DNA Repair Disorders. Clin Cancer Res. 2017 Jun 01; 23(11):e23-e31. PMID: 28572264.
      Citations: 16     Fields:    Translation:HumansCells
    8. Flores RJ, Kelly AJ, Li Y, Nakka M, Barkauskas DA, Krailo M, Wang LL, Perlaky L, Lau CC, Hicks MJ, Man TK. A novel prognostic model for osteosarcoma using circulating CXCL10 and FLT3LG. Cancer. 2017 Jan 01; 123(1):144-154. PMID: 27529817.
      Citations: 9     Fields:    Translation:Humans
    9. Tao L, Chu L, Wang LI, Moy L, Brammer M, Song C, Green M, Kurian AW, Gomez SL, Clarke CA. Occurrence and outcome of de novo metastatic breast cancer by subtype in a large, diverse population. Cancer Causes Control. 2016 09; 27(9):1127-38. PMID: 27496200.
      Citations: 8     Fields:    Translation:Humans
    10. Lu L, Jin W, Wang LL. Aging in Rothmund-Thomson syndrome and related RECQL4 genetic disorders. Ageing Res Rev. 2017 Jan; 33:30-35. PMID: 27287744.
      Citations: 11     Fields:    Translation:Humans
    11. Arora A, Agarwal D, Abdel-Fatah TM, Lu H, Croteau DL, Moseley P, Aleskandarany MA, Green AR, Ball G, Rakha EA, Chan SY, Ellis IO, Wang LL, Zhao Y, Balajee AS, Bohr VA, Madhusudan S. RECQL4 helicase has oncogenic potential in sporadic breast cancers. J Pathol. 2016 Mar; 238(4):495-501. PMID: 26690729.
      Citations: 12     Fields:    Translation:HumansCells
    12. Lu L, Harutyunyan K, Jin W, Wu J, Yang T, Chen Y, Joeng KS, Bae Y, Tao J, Dawson BC, Jiang MM, Lee B, Wang LL. RECQL4 Regulates p53 Function In Vivo During Skeletogenesis. J Bone Miner Res. 2015 Jun; 30(6):1077-89. PMID: 25556649.
      Citations: 9     Fields:    Translation:HumansAnimals
    13. Ahmed N, Brawley VS, Hegde M, Robertson C, Ghazi A, Gerken C, Liu E, Dakhova O, Ashoori A, Corder A, Gray T, Wu MF, Liu H, Hicks J, Rainusso N, Dotti G, Mei Z, Grilley B, Gee A, Rooney CM, Brenner MK, Heslop HE, Wels WS, Wang LL, Anderson P, Gottschalk S. Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma. J Clin Oncol. 2015 May 20; 33(15):1688-96. PMID: 25800760.
      Citations: 269     Fields:    Translation:HumansCellsCTClinical Trials
    14. Mata M, Vera JF, Gerken C, Rooney CM, Miller T, Pfent C, Wang LL, Wilson-Robles HM, Gottschalk S. Toward immunotherapy with redirected T cells in a large animal model: ex vivo activation, expansion, and genetic modification of canine T cells. J Immunother. 2014 Oct; 37(8):407-15. PMID: 25198528.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    15. Hadley C, Gressot LV, Patel AJ, Wang LL, Flores RJ, Whitehead WE, Luerssen TG, Jea A, Bollo RJ. Osteosarcoma of the cranial vault and skull base in pediatric patients. J Neurosurg Pediatr. 2014 Apr; 13(4):380-7. PMID: 24483254.
      Citations: 9     Fields:    Translation:Humans
    16. Lu L, Jin W, Liu H, Wang LL. RECQ DNA helicases and osteosarcoma. Adv Exp Med Biol. 2014; 804:129-45. PMID: 24924172.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    17. Rainusso N, Wang LL, Yustein JT. The adolescent and young adult with cancer: state of the art -- bone tumors. Curr Oncol Rep. 2013 Aug; 15(4):296-307. PMID: 23690089.
      Citations: 37     Fields:    Translation:Humans
    18. Kakarla S, Chow KK, Mata M, Shaffer DR, Song XT, Wu MF, Liu H, Wang LL, Rowley DR, Pfizenmaier K, Gottschalk S. Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma. Mol Ther. 2013 Aug; 21(8):1611-20. PMID: 23732988.
      Citations: 88     Fields:    Translation:HumansAnimalsCells
    19. Rainusso N, Man TK, Lau CC, Hicks J, Shen JJ, Yu A, Wang LL, Rosen JM. Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse model. Cancer Biol Ther. 2011 Aug 15; 12(4):278-87. PMID: 21617384.
      Citations: 11     Translation:HumansAnimalsCells
    20. Brufsky AM, Mayer M, Rugo HS, Kaufman PA, Tan-Chiu E, Tripathy D, Tudor IC, Wang LI, Brammer MG, Shing M, Yood MU, Yardley DA. Central nervous system metastases in patients with HER2-positive metastatic breast cancer: incidence, treatment, and survival in patients from registHER. Clin Cancer Res. 2011 Jul 15; 17(14):4834-43. PMID: 21768129.
      Citations: 97     Fields:    Translation:Humans
    21. Killen MW, Taylor TL, Stults DM, Jin W, Wang LL, Moscow JA, Pierce AJ. Configuration and rearrangement of the human GAGE gene clusters. Am J Transl Res. 2011 May 15; 3(3):234-42. PMID: 21654878.
      Citations: 4     
    22. Clericuzio C, Harutyunyan K, Jin W, Erickson RP, Irvine AD, McLean WH, Wen Y, Bagatell R, Griffin TA, Shwayder TA, Plon SE, Wang LL. Identification of a novel C16orf57 mutation in Athabaskan patients with Poikiloderma with Neutropenia. Am J Med Genet A. 2011 Feb; 155A(2):337-42. PMID: 21271650.
      Citations: 10     Translation:HumansCells
    23. Padhy D, Madhuri V, Pulimood SA, Danda S, Walter NM, Wang LL. Metatarsal osteosarcoma in Rothmund-Thomson syndrome: a case report. J Bone Joint Surg Am. 2010 Mar; 92(3):726-30. PMID: 20194333.
      Citations: 1     Fields:    Translation:Humans
    24. Engin F, Bertin T, Ma O, Jiang MM, Wang L, Sutton RE, Donehower LA, Lee B. Notch signaling contributes to the pathogenesis of human osteosarcomas. Hum Mol Genet. 2009 Apr 15; 18(8):1464-70. PMID: 19228774.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    25. Sandler AB, Schiller JH, Gray R, Dimery I, Brahmer J, Samant M, Wang LI, Johnson DH. Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with Carboplatin and Paclitaxel plus bevacizumab. J Clin Oncol. 2009 Mar 20; 27(9):1405-12. PMID: 19224857.
      Citations: 46     Fields:    Translation:HumansCTClinical Trials
    26. Siitonen HA, Sotkasiira J, Biervliet M, Benmansour A, Capri Y, Cormier-Daire V, Crandall B, Hannula-Jouppi K, Hennekam R, Herzog D, Keymolen K, Lipsanen-Nyman M, Miny P, Plon SE, Riedl S, Sarkar A, Vargas FR, Verloes A, Wang LL, Kääriäinen H, Kestilä M. The mutation spectrum in RECQL4 diseases. Eur J Hum Genet. 2009 Feb; 17(2):151-8. PMID: 18716613.
      Citations: 73     Fields:    Translation:Humans
    27. Mehollin-Ray AR, Kozinetz CA, Schlesinger AE, Guillerman RP, Wang LL. Radiographic abnormalities in Rothmund-Thomson syndrome and genotype-phenotype correlation with RECQL4 mutation status. AJR Am J Roentgenol. 2008 Aug; 191(2):W62-6. PMID: 18647888.
      Citations: 13     Fields:    Translation:Humans
    28. Jin W, Liu H, Zhang Y, Otta SK, Plon SE, Wang LL. Sensitivity of RECQL4-deficient fibroblasts from Rothmund-Thomson syndrome patients to genotoxic agents. Hum Genet. 2008 Jul; 123(6):643-53. PMID: 18504617.
      Citations: 32     Fields:    Translation:HumansCells
    29. Engin F, Yao Z, Yang T, Zhou G, Bertin T, Jiang MM, Chen Y, Wang L, Zheng H, Sutton RE, Boyce BF, Lee B. Dimorphic effects of Notch signaling in bone homeostasis. Nat Med. 2008 Mar; 14(3):299-305. PMID: 18297084.
      Citations: 164     Fields:    Translation:HumansAnimalsCells
    30. Hicks MJ, Roth JR, Kozinetz CA, Wang LL. Clinicopathologic features of osteosarcoma in patients with Rothmund-Thomson syndrome. J Clin Oncol. 2007 Feb 01; 25(4):370-5. PMID: 17264332.
      Citations: 14     Fields:    Translation:Humans
    31. Broom MA, Wang LL, Otta SK, Knutsen AP, Siegfried E, Batanian JR, Kelly ME, Shah M. Successful umbilical cord blood stem cell transplantation in a patient with Rothmund-Thomson syndrome and combined immunodeficiency. Clin Genet. 2006 Apr; 69(4):337-43. PMID: 16630167.
      Citations: 9     Fields:    Translation:Humans
    32. Wang LL. Biology of osteogenic sarcoma. Cancer J. 2005 Jul-Aug; 11(4):294-305. PMID: 16197719.
      Citations: 48     Fields:    Translation:Humans
    33. Van Maldergem L, Siitonen HA, Jalkh N, Chouery E, De Roy M, Delague V, Muenke M, Jabs EW, Cai J, Wang LL, Plon SE, Fourneau C, Kestilä M, Gillerot Y, Mégarbané A, Verloes A. Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene. J Med Genet. 2006 Feb; 43(2):148-52. PMID: 15964893.
      Citations: 60     Fields:    Translation:Humans
    34. Liu G, Zhou W, Park S, Wang LI, Miller DP, Wain JC, Lynch TJ, Su L, Christiani DC. The SOD2 Val/Val genotype enhances the risk of nonsmall cell lung carcinoma by p53 and XRCC1 polymorphisms. Cancer. 2004 Dec 15; 101(12):2802-8. PMID: 15534883.
      Citations: 17     Fields:    Translation:Humans
    35. Wang LI, Neuberg D, Christiani DC. Asbestos exposure, manganese superoxide dismutase (MnSOD) genotype, and lung cancer risk. J Occup Environ Med. 2004 Jun; 46(6):556-64. PMID: 15213518.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    36. Wang LL, Gannavarapu A, Kozinetz CA, Levy ML, Lewis RA, Chintagumpala MM, Ruiz-Maldanado R, Contreras-Ruiz J, Cunniff C, Erickson RP, Lev D, Rogers M, Zackai EH, Plon SE. Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome. J Natl Cancer Inst. 2003 May 07; 95(9):669-74. PMID: 12734318.
      Citations: 78     Fields:    Translation:Humans
    37. Wang LL, Gannavarapu A, Clericuzio CL, Erickson RP, Irvine AD, Plon SE. Absence of RECQL4 mutations in poikiloderma with neutropenia in Navajo and non-Navajo patients. Am J Med Genet A. 2003 Apr 30; 118A(3):299-301. PMID: 12673665.
      Citations: 9     Translation:Humans
    38. Wang LL, Worley K, Gannavarapu A, Chintagumpala MM, Levy ML, Plon SE. Intron-size constraint as a mutational mechanism in Rothmund-Thomson syndrome. Am J Hum Genet. 2002 Jul; 71(1):165-7. PMID: 12016592.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    39. Wang LL, Levy ML, Lewis RA, Chintagumpala MM, Lev D, Rogers M, Plon SE. Clinical manifestations in a cohort of 41 Rothmund-Thomson syndrome patients. Am J Med Genet. 2001 Jul 22; 102(1):11-7. PMID: 11471165.
      Citations: 67     Fields:    Translation:HumansCells
    WANG's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (234)
    Explore
    _
    Co-Authors (41)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _