"Troponin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Descriptor ID |
D019210
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MeSH Number(s) |
D05.500.945.925 D05.750.078.730.825.925 D12.776.210.500.910.925 D12.776.220.525.825.925
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Troponin I".
Below are MeSH descriptors whose meaning is more specific than "Troponin I".
This graph shows the total number of publications written about "Troponin I" by people in this website by year, and whether "Troponin I" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1997 | 1 | 0 | 1 |
1998 | 1 | 0 | 1 |
1999 | 2 | 2 | 4 |
2000 | 0 | 1 | 1 |
2001 | 1 | 0 | 1 |
2002 | 1 | 1 | 2 |
2003 | 4 | 0 | 4 |
2005 | 2 | 0 | 2 |
2006 | 1 | 1 | 2 |
2007 | 3 | 1 | 4 |
2008 | 1 | 1 | 2 |
2009 | 0 | 2 | 2 |
2010 | 2 | 0 | 2 |
2011 | 2 | 2 | 4 |
2012 | 1 | 1 | 2 |
2013 | 3 | 5 | 8 |
2014 | 0 | 3 | 3 |
2015 | 2 | 2 | 4 |
2016 | 5 | 0 | 5 |
2017 | 3 | 1 | 4 |
2018 | 6 | 1 | 7 |
2019 | 4 | 3 | 7 |
2020 | 9 | 1 | 10 |
2021 | 1 | 4 | 5 |
2022 | 0 | 3 | 3 |
2023 | 0 | 1 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Troponin I" by people in Profiles.
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High-Sensitivity Cardiac Troponins I and T and Cardiovascular Outcomes: Findings from the Systolic Blood Pressure Intervention Trial (SPRINT). Clin Chem. 2024 Feb 07; 70(2):414-424.
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Methods of the PivotaL triAl of the Atellica VTLi point of care emergencY dePartment high sensitivity troponin evalUationS. Clin Biochem. 2023 Nov; 121-122:110679.
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Concentration of hs-Troponin in small cohort of transgender patients. Clin Chim Acta. 2023 Jan 15; 539:66-69.
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Quantitation of cardiac troponin I in cancer patients treated with immune checkpoint inhibitors: a case-control study. Clin Chem Lab Med. 2023 01 27; 61(1):154-161.
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Prognosis is worse with elevated cardiac troponin in nonacute coronary syndrome compared with acute coronary syndrome. Coron Artery Dis. 2022 08 01; 33(5):376-384.
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Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations With Atrial Fibrillation. Circ Genom Precis Med. 2021 12; 14(6):e003460.
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Ideal high sensitivity troponin baseline cutoff for patients with renal dysfunction. Am J Emerg Med. 2022 06; 56:323-324.
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ST-elevation in an adolescent with COVID-19: Myopericarditis or myocardial infarction? Am J Emerg Med. 2022 Feb; 52:271.e1-271.e3.
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Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis. Circulation. 2021 06 15; 143(24):2370-2383.
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Discordance of High-Sensitivity Troponin Assays in Patients With Suspected Acute Coronary Syndromes. J Am Coll Cardiol. 2021 03 30; 77(12):1487-1499.