"Tyrosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
| Descriptor ID |
D014443
|
| MeSH Number(s) |
D12.125.072.050.875
|
| Concept/Terms |
Tyrosine- Tyrosine
- para-Tyrosine
- para Tyrosine
- Tyrosine, L-isomer
- Tyrosine, L isomer
- L-Tyrosine
- L Tyrosine
|
Below are MeSH descriptors whose meaning is more general than "Tyrosine".
Below are MeSH descriptors whose meaning is more specific than "Tyrosine".
This graph shows the total number of publications written about "Tyrosine" by people in this website by year, and whether "Tyrosine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 11 | 16 |
| 1996 | 2 | 4 | 6 |
| 1997 | 3 | 6 | 9 |
| 1998 | 10 | 4 | 14 |
| 1999 | 4 | 14 | 18 |
| 2000 | 3 | 9 | 12 |
| 2001 | 4 | 10 | 14 |
| 2002 | 7 | 11 | 18 |
| 2003 | 7 | 12 | 19 |
| 2004 | 3 | 6 | 9 |
| 2005 | 5 | 16 | 21 |
| 2006 | 3 | 13 | 16 |
| 2007 | 1 | 7 | 8 |
| 2008 | 5 | 10 | 15 |
| 2009 | 2 | 5 | 7 |
| 2010 | 1 | 8 | 9 |
| 2011 | 3 | 8 | 11 |
| 2012 | 0 | 5 | 5 |
| 2013 | 1 | 6 | 7 |
| 2014 | 0 | 6 | 6 |
| 2015 | 1 | 6 | 7 |
| 2016 | 3 | 4 | 7 |
| 2017 | 1 | 2 | 3 |
| 2018 | 2 | 4 | 6 |
| 2019 | 1 | 5 | 6 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 2 | 2 |
| 2022 | 0 | 5 | 5 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Tyrosine" by people in Profiles.
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The intrinsic substrate specificity of the human tyrosine kinome. Nature. 2024 May; 629(8014):1174-1181.
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Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy. Sci Adv. 2024 Feb 02; 10(5):eadg7887.
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ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries. J Am Chem Soc. 2023 11 22; 145(46):25283-25292.
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The combined action of the intracellular regions regulates FGFR2 kinase activity. Commun Biol. 2023 07 14; 6(1):728.
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Aberrant function of pathogenic STAT3 mutant proteins is linked to altered stability of monomers and homodimers. Blood. 2023 03 23; 141(12):1411-1424.
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Targeting the ALK-CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex. Nat Cancer. 2022 10; 3(10):1211-1227.
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Targeting RAS Mutant Colorectal Cancer with Dual Inhibition of MEK and CDK4/6. Cancer Res. 2022 Sep 16; 82(18):3335-3344.
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Magnetic Control of Cells by Chemical Fabrication of Melanin. J Am Chem Soc. 2022 09 21; 144(37):16720-16725.
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STAT3 Inhibits Autocrine IFN Signaling in Type I Conventional Dendritic Cells. J Immunol. 2022 10 01; 209(7):1286-1299.
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Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state. Mol Cell. 2022 03 17; 82(6):1089-1106.e12.