Hypoxia-Inducible Factor 1, alpha Subunit
"Hypoxia-Inducible Factor 1, alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted for degradation by VHL TUMOR SUPPRESSOR PROTEIN.
Descriptor ID |
D051795
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MeSH Number(s) |
D12.776.260.103.625.750 D12.776.930.125.625.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1, alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1, alpha Subunit".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in this website by year, and whether "Hypoxia-Inducible Factor 1, alpha Subunit" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 4 | 4 |
2002 | 0 | 8 | 8 |
2003 | 0 | 8 | 8 |
2004 | 0 | 14 | 14 |
2005 | 0 | 11 | 11 |
2006 | 2 | 2 | 4 |
2007 | 7 | 6 | 13 |
2008 | 4 | 5 | 9 |
2009 | 7 | 7 | 14 |
2010 | 10 | 3 | 13 |
2011 | 6 | 12 | 18 |
2012 | 8 | 6 | 14 |
2013 | 3 | 6 | 9 |
2014 | 5 | 7 | 12 |
2015 | 4 | 8 | 12 |
2016 | 5 | 5 | 10 |
2017 | 11 | 8 | 19 |
2018 | 8 | 10 | 18 |
2019 | 5 | 5 | 10 |
2020 | 3 | 3 | 6 |
2021 | 4 | 1 | 5 |
2023 | 0 | 3 | 3 |
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Below are the most recent publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in Profiles.
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Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma. Clin Cancer Res. 2023 12 15; 29(24):5183-5195.
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Radiation-induced bone loss in mice is ameliorated by inhibition of HIF-2a in skeletal progenitor cells. Sci Transl Med. 2023 11 29; 15(724):eabo5217.
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ABL kinases regulate the stabilization of HIF-1a and MYC through?CPSF1. Proc Natl Acad Sci U S A. 2023 04 18; 120(16):e2210418120.
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Vascular endothelial growth factor (VEGF) and hypoxia inducible factor-1 alpha (HIF-1?) in lacrimal gland Adenoid cystic carcinoma: Correlation with clinical outcome. Ann Diagn Pathol. 2022 Feb; 56:151846.
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An airway organoid-based screen identifies a role for the HIF1a-glycolysis axis in SARS-CoV-2 infection. Cell Rep. 2021 11 09; 37(6):109920.
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Adhatoda Vasica attenuates inflammatory and hypoxic responses in preclinical mouse models: potential for repurposing in COVID-19-like conditions. Respir Res. 2021 Apr 06; 22(1):99.
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Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells. J Clin Invest. 2021 04 01; 131(7).
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Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1a regulator. Cancer Sci. 2021 Apr; 112(4):1614-1623.
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Altered Regulation of HIF-1a in Naive- and Drug-Resistant EGFR-Mutant NSCLC: Implications for a Vascular Endothelial Growth Factor-Dependent Phenotype. J Thorac Oncol. 2021 03; 16(3):439-451.
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Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function. Cell Stem Cell. 2021 02 04; 28(2):257-272.e11.