Amino Acid Transport System ASC
"Amino Acid Transport System ASC" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous sodium-dependent neutral amino acid transporter. The preferred substrates for this transporter system include ALANINE; SERINE; and CYSTEINE.
| Descriptor ID |
D026962
|
| MeSH Number(s) |
D12.776.157.530.200.500.200 D12.776.543.585.200.500.200
|
| Concept/Terms |
Amino Acid Transport System ASC- Amino Acid Transport System ASC
- System ASC Transporter Proteins
- System ASC Transporter
- Amino Acid Transport System ASC Proteins
- Amino Acid Transporter ASC
|
Below are MeSH descriptors whose meaning is more general than "Amino Acid Transport System ASC".
Below are MeSH descriptors whose meaning is more specific than "Amino Acid Transport System ASC".
This graph shows the total number of publications written about "Amino Acid Transport System ASC" by people in this website by year, and whether "Amino Acid Transport System ASC" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2019 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amino Acid Transport System ASC" by people in Profiles.
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Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats. Placenta. 2021 09 01; 112:36-44.
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TFEB controls retromer expression in response to nutrient availability. J Cell Biol. 2019 12 02; 218(12):3954-3966.
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Rational combination with PDK1 inhibition overcomes cetuximab resistance in head and neck squamous cell carcinoma. JCI Insight. 2019 10 03; 4(19).
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AP1G1 is involved in cetuximab-mediated downregulation of ASCT2-EGFR complex and sensitization of human head and neck squamous cell carcinoma cells to ROS-induced apoptosis. Cancer Lett. 2017 11 01; 408:33-42.
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Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer. Mol Cancer Res. 2017 08; 15(8):1017-1028.
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ASCT2 (SLC1A5) is an EGFR-associated protein that can be co-targeted by cetuximab to sensitize cancer cells to ROS-induced apoptosis. Cancer Lett. 2016 10 10; 381(1):23-30.
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Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. Cancer Cell. 2015 Mar 09; 27(3):354-69.
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Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation. Immunity. 2014 May 15; 40(5):692-705.
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Expression of neutral amino acid transporter ASCT2 in human prostate. Anticancer Res. 2003 Jul-Aug; 23(4):3413-8.