"Pyrimidines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.
| Descriptor ID |
D011743
|
| MeSH Number(s) |
D03.383.742
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pyrimidines".
Below are MeSH descriptors whose meaning is more specific than "Pyrimidines".
This graph shows the total number of publications written about "Pyrimidines" by people in this website by year, and whether "Pyrimidines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 2 | 0 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2003 | 5 | 2 | 7 |
| 2004 | 7 | 3 | 10 |
| 2005 | 3 | 1 | 4 |
| 2006 | 5 | 2 | 7 |
| 2007 | 6 | 4 | 10 |
| 2008 | 9 | 2 | 11 |
| 2009 | 3 | 1 | 4 |
| 2010 | 4 | 2 | 6 |
| 2011 | 11 | 9 | 20 |
| 2012 | 4 | 5 | 9 |
| 2013 | 10 | 10 | 20 |
| 2014 | 10 | 6 | 16 |
| 2015 | 8 | 7 | 15 |
| 2016 | 17 | 5 | 22 |
| 2017 | 9 | 14 | 23 |
| 2018 | 17 | 9 | 26 |
| 2019 | 5 | 7 | 12 |
| 2020 | 5 | 8 | 13 |
| 2021 | 4 | 6 | 10 |
| 2022 | 1 | 10 | 11 |
| 2023 | 2 | 6 | 8 |
| 2024 | 6 | 7 | 13 |
| 2025 | 6 | 8 | 14 |
| 2026 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Pyrimidines" by people in Profiles.
-
Nilotinib-Induced Retinal Artery Thrombosis in a Patient With Chronic Myeloid Leukaemia: A Rare Case. Cancer Rep (Hoboken). 2026 Feb; 9(2):e70501.
-
Evaluating the Antiproliferative Effects of Tri(2-Furyl)- and Triphenylphosphine-Gold(I) Pyridyl- and Pyrimidine-Thiolate Complexes. Biomolecules. 2026 Jan 15; 16(1).
-
Design, synthesis, and biological evaluation of Benzimidazole-Aminopyrimidine hybrids as selective P38a MAPK inhibitors targeting Neuroinflammation in an AlCl3-induced rat model of Alzheimer's disease. Bioorg Chem. 2026 Feb; 169:109391.
-
Capivasertib plus abiraterone in PTEN-deficient metastatic hormone-sensitive prostate cancer: CAPItello-281 phase III study. Ann Oncol. 2026 Jan; 37(1):53-68.
-
COOKIE-Pro: covalent inhibitor binding kinetics profiling on the proteome scale. Nat Commun. 2025 Sep 30; 16(1):8373.
-
Revisiting the Effect of Udenafil on Exercise Performance in Patients With Fontan Circulation: Results of a Post Hoc Analysis of the FUEL Trial. J Am Heart Assoc. 2025 Aug 19; 14(16):e041348.
-
PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth. Cell Rep. 2025 Aug 26; 44(8):116071.
-
N-acetylaspartate from fat cells regulates postprandial body temperature. Nat Metab. 2025 Aug; 7(8):1524-1535.
-
Risdiplam treatment following onasemnogene abeparvovec in individuals with spinal muscular atrophy: a multicenter case series. BMC Neurol. 2025 Jul 07; 25(1):283.
-
Population Pharmacokinetic and Exposure-Response Analyses of Ibrutinib Combined With Bendamustine and Rituximab in Patients With Mantle Cell Lymphoma. CPT Pharmacometrics Syst Pharmacol. 2025 Oct; 14(10):1562-1574.