Macromolecular Substances
"Macromolecular Substances" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.
| Descriptor ID |
D046911
|
| MeSH Number(s) |
D05
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Macromolecular Substances".
Below are MeSH descriptors whose meaning is more specific than "Macromolecular Substances".
This graph shows the total number of publications written about "Macromolecular Substances" by people in this website by year, and whether "Macromolecular Substances" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 12 | 12 |
| 1995 | 0 | 15 | 15 |
| 1996 | 0 | 11 | 11 |
| 1997 | 0 | 4 | 4 |
| 1998 | 0 | 6 | 6 |
| 1999 | 0 | 7 | 7 |
| 2000 | 0 | 13 | 13 |
| 2001 | 0 | 6 | 6 |
| 2002 | 0 | 12 | 12 |
| 2003 | 0 | 19 | 19 |
| 2004 | 1 | 15 | 16 |
| 2005 | 0 | 7 | 7 |
| 2006 | 0 | 4 | 4 |
| 2007 | 1 | 3 | 4 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 2 | 3 |
| 2013 | 3 | 3 | 6 |
| 2014 | 3 | 0 | 3 |
| 2015 | 3 | 0 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Macromolecular Substances" by people in Profiles.
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Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na+ Channel 1.2 Macromolecular Complex. Cells. 2021 11 10; 10(11).
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Electron crystallography of chiral and non-chiral small molecules. Ultramicroscopy. 2022 01; 232:113417.
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Designer Condensates: A Toolkit for the Biomolecular Architect. J Mol Biol. 2021 06 11; 433(12):166837.
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Structural overview of macromolecular machines involved in ribosome biogenesis. Curr Opin Struct Biol. 2021 04; 67:51-60.
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Macromolecular modeling and design in Rosetta: recent methods and frameworks. Nat Methods. 2020 07; 17(7):665-680.
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Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology. Curr Opin Struct Biol. 2019 10; 58:197-213.
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Translating preclinical MRI methods to clinical oncology. J Magn Reson Imaging. 2019 11; 50(5):1377-1392.
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Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates. Biomolecules. 2019 02 19; 9(2).
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Dynamic cytoplasmic projections connect mammalian spermatogonia in vivo. Development. 2018 08 13; 145(15).
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Ion channels as part of macromolecular multiprotein complexes : Clinical significance. Herzschrittmacherther Elektrophysiol. 2018 Mar; 29(1):30-35.