"TRPV Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels named after the vanilloid receptor. They are very sensitive to TEMPERATURE; hot spicy food, and CAPSAICIN. They contain a TRP domain (a five-turn amphipathic helix with an invariant TRYPTOPHAN) and ANKYRIN repeats. Selectivity for CALCIUM over SODIUM ranges from 3 to 100 fold.
| Descriptor ID |
D050916
|
| MeSH Number(s) |
D12.776.157.530.400.901.888
|
| Concept/Terms |
TRPV Cation Channels- TRPV Cation Channels
- Cation Channels, TRPV
- Channels, TRPV Cation
- Capsaicin Receptors
- Receptors, Capsaicin
- Vanilloid Receptors
- Receptors, Vanilloid
|
Below are MeSH descriptors whose meaning is more general than "TRPV Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPV Cation Channels".
This graph shows the total number of publications written about "TRPV Cation Channels" by people in this website by year, and whether "TRPV Cation Channels" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 3 | 2 | 5 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 2 | 2 | 4 |
| 2026 | 1 | 1 | 2 |
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Below are the most recent publications written about "TRPV Cation Channels" by people in Profiles.
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A metabolic alarmin from keratinocytes potentiates systemic humoral immunity. Nature. 2026 04; 652(8108):209-219.
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Results of a Randomized, Double-Masked, Placebo-Controlled Phase 1/2 Study of a TRPV1 Antagonist SJP-0132 in Participants With Dry Eye Disease. Am J Ophthalmol. 2026 Apr; 284:216-225.
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Sensory neuron-expressed FGF13 controls nociceptive signaling in diabetic neuropathy models. J Clin Invest. 2025 Jul 15; 135(14).
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An in vitro platform for characterizing axonal electrophysiology of individual human iPSC-derived nociceptors. Biosens Bioelectron. 2025 Aug 01; 281:117418.
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Combined clinical, structural and cellular studies discriminate pathogenic and benign TRPV4 variants. Brain. 2025 Feb 03; 148(2):564-579.
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TRPV4 neuromuscular disease registry highlights bulbar, skeletal and proximal limb manifestations. Brain. 2025 Jan 07; 148(1):238-251.
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Piezoelectric Analgesia Blocks Cancer-Induced Bone Pain. Adv Mater. 2024 09; 36(36):e2403979.
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Ghrelin polymorphism/TRPV1 receptor expression in Egyptian IBS patients. Cytokine. 2022 04; 152:155827.
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Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension. Nat Commun. 2021 03 04; 12(1):1444.
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TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca2. Nat Commun. 2020 05 29; 11(1):2679.