Chemical and Drug Induced Liver Injury
"Chemical and Drug Induced Liver Injury" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Descriptor ID |
D056486
|
| MeSH Number(s) |
C06.552.195 C25.100.562 C25.723.260
|
| Concept/Terms |
Chemically-Induced Liver Toxicity- Chemically-Induced Liver Toxicity
- Chemically Induced Liver Toxicity
- Chemically-Induced Liver Toxicities
- Liver Toxicities, Chemically-Induced
- Liver Toxicity, Chemically-Induced
- Toxicities, Chemically-Induced Liver
- Toxicity, Chemically-Induced Liver
Drug-Induced Acute Liver Injury- Drug-Induced Acute Liver Injury
- Drug Induced Acute Liver Injury
- Liver Injury, Drug-Induced, Acute
- Acute Liver Injury, Drug-Induced
- Acute Liver Injury, Drug Induced
Hepatitis, Toxic- Hepatitis, Toxic
- Toxic Hepatitis
- Hepatitides, Toxic
- Toxic Hepatitides
Drug-Induced Liver Disease- Drug-Induced Liver Disease
- Disease, Drug-Induced Liver
- Diseases, Drug-Induced Liver
- Drug Induced Liver Disease
- Drug-Induced Liver Diseases
- Liver Disease, Drug-Induced
- Liver Diseases, Drug-Induced
- Drug-Induced Liver Injury
- Drug Induced Liver Injury
- Drug-Induced Liver Injuries
- Injuries, Drug-Induced Liver
- Injury, Drug-Induced Liver
- Liver Injuries, Drug-Induced
- Liver Injury, Drug-Induced
- Liver Injury, Drug Induced
Hepatitis, Drug-Induced- Hepatitis, Drug-Induced
- Drug-Induced Hepatitides
- Drug-Induced Hepatitis
- Hepatitides, Drug-Induced
- Hepatitis, Drug Induced
|
Below are MeSH descriptors whose meaning is more general than "Chemical and Drug Induced Liver Injury".
Below are MeSH descriptors whose meaning is more specific than "Chemical and Drug Induced Liver Injury".
This graph shows the total number of publications written about "Chemical and Drug Induced Liver Injury" by people in this website by year, and whether "Chemical and Drug Induced Liver Injury" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2004 | 2 | 1 | 3 |
| 2005 | 2 | 0 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 1 | 3 |
| 2013 | 5 | 1 | 6 |
| 2014 | 3 | 0 | 3 |
| 2015 | 5 | 2 | 7 |
| 2016 | 6 | 1 | 7 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 7 | 2 | 9 |
| 2020 | 4 | 1 | 5 |
| 2021 | 3 | 0 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
| 2024 | 4 | 0 | 4 |
| 2025 | 5 | 0 | 5 |
| 2026 | 2 | 0 | 2 |
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Below are the most recent publications written about "Chemical and Drug Induced Liver Injury" by people in Profiles.
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Lipidomic profiles associated with treatment related hepatotoxicity in children with acute lymphoblastic leukemia. Support Care Cancer. 2026 Feb 17; 34(3):209.
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Development of retrieval-augmented generation-based large language model for drug-induced liver injury using Livertox data. Hepatol Commun. 2026 Mar 01; 10(3).
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Ataxia-telangiectasia mutated activation mediates transforming growth factor beta signaling in acetaminophen-induced liver injury in mice. Physiol Rep. 2025 Dec; 13(23):e70695.
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An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy. Blood Adv. 2025 Nov 25; 9(22):5802-5810.
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Phytoconstituents as therapeutic agents in combating methotrexate-induced hepatotoxicity and nephrotoxicity. Expert Opin Drug Metab Toxicol. 2025 Nov-Dec; 21(11-12):1287-1305.
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Characterization of hepatic pathology during azoxymethane-induced acute liver failure. World J Gastroenterol. 2025 Mar 28; 31(12):103952.
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Newer formulations of oral testosterone undecanoate: development and liver side effects. Sex Med Rev. 2025 Jan 31; 13(1):33-40.
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Macrophage Therapy for Acute Liver Injury (MAIL): a study protocol for a phase 1 randomised, open-label, dose-escalation study to evaluate safety, tolerability and activity of allogeneic alternatively activated macrophages in patients with paracetamol-induced acute liver injury in the UK. BMJ Open. 2024 Dec 09; 14(12):e089417.
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Differentiating Ischemic Hepatitis from Acetaminophen Overdose in Acute Liver Failure: Role of Acetaminophen Adducts-Ischemic Hepatitis vs Acetaminophen Overdose. Dig Dis Sci. 2024 Oct; 69(10):3952-3961.
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Impact of Diabetes, Drug-Induced Liver Injury, and Sepsis on Outcomes in Metabolic Dysfunction Associated Fatty Liver Disease-Related Acute-on-Chronic Liver Failure. Am J Gastroenterol. 2025 Apr 01; 120(4):816-826.