Insulin-Like Growth Factor II
"Insulin-Like Growth Factor II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.
| Descriptor ID |
D007335
|
| MeSH Number(s) |
D12.644.276.937.420 D12.776.124.862.425 D12.776.467.937.420 D23.529.937.420
|
| Concept/Terms |
Insulin-Like Growth Factor II- Insulin-Like Growth Factor II
- IGF-II
- Insulin Like Growth Factor II
- Insulin-Like Somatomedin Peptide II
- Insulin Like Somatomedin Peptide II
- Multiplication-Stimulating Factor
- Factor, Multiplication-Stimulating
- Multiplication Stimulating Factor
- Somatomedin A
- Somatomedin MSA
- IGF-2
- Multiplication-Stimulating Activity
- Multiplication Stimulating Activity
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor II".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor II".
This graph shows the total number of publications written about "Insulin-Like Growth Factor II" by people in this website by year, and whether "Insulin-Like Growth Factor II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 3 | 4 |
| 2002 | 1 | 1 | 2 |
| 2004 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 2 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor II" by people in Profiles.
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H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions. Nat Commun. 2021 01 29; 12(1):719.
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Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group. Sci Rep. 2020 07 23; 10(1):12318.
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Role of Cyclooxygenase-2 Pathway in Creating an Immunosuppressive Microenvironment and in Initiation and Progression of Wilms' Tumor. Neoplasia. 2017 03; 19(3):237-249.
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Structural and transcriptomic response to antenatal corticosteroids in an Erk3-null mouse model of respiratory?distress. Am J Obstet Gynecol. 2016 09; 215(3):384.e1-384.e89.
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Alterations in expression of imprinted genes from the H19/IGF2 loci in a multigenerational model of intrauterine growth restriction (IUGR). Am J Obstet Gynecol. 2016 05; 214(5):625.e1-625.e11.
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Insulin-like Growth Factor 2 Gene Expression Molecularly Differentiates Pleuropulmonary Blastoma and Embryonal Rhabdomyosarcoma. J Pediatr Hematol Oncol. 2015 Aug; 37(6):e356-60.
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Prognostic and Predictive Biomarkers in Colorectal Cancer: Implications for the Clinical Surgeon. Ann Surg Oncol. 2015 Oct; 22(11):3433-50.
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Improved detection of stage I non-small cell lung cancer with a serum-based assay. J Thorac Cardiovasc Surg. 2015 Mar; 149(3):735-6.
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Prognostic implications of tumoral expression of insulin like growth factors 1 and 2 in patients with non-small-cell lung cancer. Clin Lung Cancer. 2014 May; 15(3):213-21.
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Parental permissions: H19 and keeping the stem cell progeny under control. Cell Stem Cell. 2013 Aug 01; 13(2):137-8.