Eukaryotic Initiation Factor-4E
"Eukaryotic Initiation Factor-4E" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide initiation factor that binds specifically to the 5' MRNA CAP STRUCTURE of MRNA in the CYTOPLASM. It is a component of the trimeric complex EIF4F.
| Descriptor ID |
D039561
|
| MeSH Number(s) |
D12.776.157.725.750.374 D12.776.835.725.868.500.750
|
| Concept/Terms |
Eukaryotic Initiation Factor-4E- Eukaryotic Initiation Factor-4E
- Eukaryotic Initiation Factor 4E
- Factor-4E, Eukaryotic Initiation
- Initiation Factor-4E, Eukaryotic
- Peptide Initiation Factor EIF-4E
- Peptide Initiation Factor EIF 4E
- EIF4E
- Eukaryotic Peptide Initiation Factor-4E
- Eukaryotic Peptide Initiation Factor 4E
- CDC33 Gene Product
- EIF-4E
- EIF 4E
|
Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-4E".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-4E".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-4E" by people in this website by year, and whether "Eukaryotic Initiation Factor-4E" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 3 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 4 | 4 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 3 | 4 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-4E" by people in Profiles.
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Immunization and Drug Metabolizing Enzymes: Focus on Hepatic Cytochrome P450 3A. Expert Rev Vaccines. 2021 05; 20(5):623-634.
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Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019 03; 38(13):2241-2262.
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Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain. J Neurosci. 2019 01 16; 39(3):393-411.
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Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling. Mol Oncol. 2018 11; 12(11):1856-1870.
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Intermittent bolus feeding promotes greater lean growth than continuous feeding in a neonatal piglet model. Am J Clin Nutr. 2018 10 01; 108(4):830-841.
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Anchimerically Activated ProTides as Inhibitors of Cap-Dependent Translation and Inducers of Chemosensitization in Mantle Cell Lymphoma. J Med Chem. 2017 10 12; 60(19):8131-8144.
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Leucine supplementation of a chronically restricted protein and energy diet enhances mTOR pathway activation but not muscle protein synthesis in neonatal pigs. Amino Acids. 2016 Jan; 48(1):257-267.
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Two Arabidopsis loci encode novel eukaryotic initiation factor 4E isoforms that are functionally distinct from the conserved plant eukaryotic initiation factor 4E. Plant Physiol. 2014 Apr; 164(4):1820-30.
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Stabilization of HIF-2a through redox regulation of mTORC2 activation and initiation of mRNA translation. Oncogene. 2013 Jun 27; 32(26):3147-55.
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Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells. Mol Endocrinol. 2012 Oct; 26(10):1732-42.