"Histone Code" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific patterns of changes made to HISTONES, that are involved in assembly, maintenance, and alteration of chromatin structural states (such as EUCHROMATIN and HETEROCHROMATIN). The changes are made by various HISTONE MODIFICATION PROCESSES that include ACETYLATION; METHYLATION; PHOSPHORYLATION; and UBIQUITINATION.
| Descriptor ID |
D042421
|
| MeSH Number(s) |
G02.111.570.060.360 G05.360.360
|
| Concept/Terms |
Histone Code- Histone Code
- Code, Histone
- Histone Marks
- Histone Mark
- Mark, Histone
- Marks, Histone
- Histone Modifications
- Modifications, Histone
|
Below are MeSH descriptors whose meaning is more general than "Histone Code".
Below are MeSH descriptors whose meaning is more specific than "Histone Code".
This graph shows the total number of publications written about "Histone Code" by people in this website by year, and whether "Histone Code" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 3 | 5 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 2 | 3 |
| 2017 | 4 | 3 | 7 |
| 2018 | 5 | 4 | 9 |
| 2019 | 2 | 2 | 4 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 4 | 6 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Histone Code" by people in Profiles.
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Neural tube defects and epigenetics: role of histone post-translational histone modifications. Epigenomics. 2024 Mar; 16(6):419-426.
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Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain. J Biol Chem. 2022 06; 298(6):101999.
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UBR7 acts as a histone chaperone for post-nucleosomal histone H3. EMBO J. 2021 12 15; 40(24):e108307.
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Role of Histone Methylation in Maintenance of Genome Integrity. Genes (Basel). 2021 06 29; 12(7).
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Inhibiting an RBM39/MLL1 epigenomic regulatory complex with dominant-negative peptides disrupts cancer cell transcription and proliferation. Cell Rep. 2021 06 01; 35(9):109156.
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Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson's disease brain. Mol Neurodegener. 2021 05 05; 16(1):31.
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Combinations of histone post-translational modifications. Biochem J. 2021 02 12; 478(3):511-532.
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Loss of H3K27 methylation identifies poor outcomes in adult-onset acute leukemia. Clin Epigenetics. 2021 01 28; 13(1):21.
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Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery. Sci Rep. 2021 01 13; 11(1):1121.
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The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells. Epigenetics Chromatin. 2020 10 23; 13(1):44.