"Lethal Dose 50" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
| Descriptor ID |
D007928
|
| MeSH Number(s) |
E05.940.402 G07.225.500 G07.690.773.875.750 G07.690.936.500.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lethal Dose 50".
Below are MeSH descriptors whose meaning is more specific than "Lethal Dose 50".
This graph shows the total number of publications written about "Lethal Dose 50" by people in this website by year, and whether "Lethal Dose 50" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lethal Dose 50" by people in Profiles.
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Antidotal efficacies of the cyanide antidote candidate dimethyl trisulfide alone and in combination with cobinamide derivatives. Toxicol Mech Methods. 2019 Jul; 29(6):438-444.
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Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease. J Infect Dis. 2019 02 15; 219(5):829-835.
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Intraspecies geographical variability in the South American tigra mariposa (Bothrops venezuelensis Sandner 1952) snake venom activities. Toxicon. 2018 Mar 15; 144:23-33.
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Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease. J Virol. 2016 01 01; 90(1):57-67.
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Comparison of Cesium-137 and X-ray Irradiators by Using Bone Marrow Transplant Reconstitution in C57BL/6J Mice. Comp Med. 2015 Jun; 65(3):165-72.
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Mitigation and treatment of radiation-induced thoracic injury with a cyclooxygenase-2 inhibitor, celecoxib. Int J Radiat Oncol Biol Phys. 2013 Feb 01; 85(2):472-6.
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Antioxidant-chemoprevention diet ameliorates late effects of total-body irradiation and supplements radioprotection by MnSOD-plasmid liposome administration. Radiat Res. 2011 Jun; 175(6):759-65.
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Deletion of Braun lipoprotein gene (lpp) and curing of plasmid pPCP1 dramatically alter the virulence of Yersinia pestis CO92 in a mouse model of pneumonic plague. Microbiology (Reading). 2009 Oct; 155(Pt 10):3247-3259.
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Characterization of the rat pneumonic plague model: infection kinetics following aerosolization of Yersinia pestis CO92. Microbes Infect. 2009 Feb; 11(2):205-14.
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Characterization of a mouse model of plague after aerosolization of Yersinia pestis CO92. Microbiology (Reading). 2008 Jul; 154(Pt 7):1939-1948.