"Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3.
| Descriptor ID |
D008049
|
| MeSH Number(s) |
D08.811.277.352.100.400
|
| Concept/Terms |
Lipase- Lipase
- Triacylglycerol Lipase
- Triolean Hydrolase
- Hydrolase, Triolean
- Triglyceridase
- Triglyceride Lipase
- Lipase, Triglyceride
- Triacylglycerol Hydrolase
- Hydrolase, Triacylglycerol
- Tributyrinase
|
Below are MeSH descriptors whose meaning is more general than "Lipase".
Below are MeSH descriptors whose meaning is more specific than "Lipase".
This graph shows the total number of publications written about "Lipase" by people in this website by year, and whether "Lipase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 2 | 2 | 4 |
| 2004 | 2 | 1 | 3 |
| 2006 | 2 | 1 | 3 |
| 2007 | 2 | 1 | 3 |
| 2008 | 2 | 2 | 4 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 2 | 3 | 5 |
| 2013 | 1 | 2 | 3 |
| 2014 | 2 | 2 | 4 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 2 | 4 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lipase" by people in Profiles.
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PNPLA3, Obesity, and Heavy Alcohol Use in Cirrhosis Patients May Exert a Synergistic Increase Hepatocellular Carcinoma Risk. Clin Gastroenterol Hepatol. 2024 Sep; 22(9):1858-1866.e4.
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Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity. Cancer Res. 2024 03 04; 84(5):703-724.
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Structure-based virtual screening to identify potential lipase inhibitors to reduce lipid storage in Wolman disorder. Adv Protein Chem Struct Biol. 2023; 133:351-363.
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Synergistic Associations of PNPLA3 I148M Variant, Alcohol Intake, and Obesity With Risk of Cirrhosis, Hepatocellular Carcinoma, and Mortality. JAMA Netw Open. 2022 10 03; 5(10):e2234221.
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Metabolic liver disease - what's in a name? Nat Rev Endocrinol. 2021 02; 17(2):79-80.
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Genotype-phenotype correlation in a large English cohort of patients with autosomal recessive ichthyosis. Br J Dermatol. 2020 03; 182(3):729-737.
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An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis. Cells. 2019 04 29; 8(5).
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Genetic Determinants of Circulating Lipoproteins in Nonalcoholic Fatty Liver Disease. J Clin Gastroenterol. 2018 May/Jun; 52(5):444-451.
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Erythrokeratoderma: a manifestation associated with multiple types of ichthyoses with different gene defects. Br J Dermatol. 2018 03; 178(3):e219-e221.
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Dyslipidaemia in nephrotic syndrome: mechanisms and treatment. Nat Rev Nephrol. 2018 Jan; 14(1):57-70.