Blood-Brain Barrier

"Blood-Brain Barrier" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.

Descriptor ID	D001812
MeSH Number(s)	A07.035 A08.186.211.035
Concept/Terms	Blood-Brain Barrier Blood-Brain Barrier Barrier, Blood-Brain Barriers, Blood-Brain Blood Brain Barrier Blood-Brain Barriers Hemato-Encephalic Barrier Barrier, Hemato-Encephalic Barriers, Hemato-Encephalic Hemato Encephalic Barrier Hemato-Encephalic Barriers Brain-Blood Barrier Barrier, Brain-Blood Barriers, Brain-Blood Brain Blood Barrier Brain-Blood Barriers

Below are MeSH descriptors whose meaning is more general than "Blood-Brain Barrier".

Anatomy [A]
Cardiovascular System [A07]
Blood-Brain Barrier [A07.035]
Nervous System [A08]
Central Nervous System [A08.186]
Brain [A08.186.211]
Blood-Brain Barrier [A08.186.211.035]

Below are MeSH descriptors whose meaning is related to "Blood-Brain Barrier".

Below are MeSH descriptors whose meaning is more specific than "Blood-Brain Barrier".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Blood-Brain Barrier" by people in this website by year, and whether "Blood-Brain Barrier" was a major or minor topic of these publications.

Bar chart showing 152 publications over 28 distinct years, with a maximum of 12 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	0	3	3
1992	0	1	1
1993	1	1	2
1996	1	3	4
1997	1	1	2
1998	0	1	1
1999	0	1	1
2000	1	4	5
2001	0	3	3
2002	0	2	2
2003	2	0	2
2004	3	3	6
2005	7	5	12
2006	3	1	4
2007	3	4	7
2008	1	1	2
2009	1	5	6
2010	5	6	11
2011	1	4	5
2012	2	6	8
2013	5	4	9
2014	4	3	7
2015	4	7	11
2016	3	3	6
2017	6	4	10
2018	3	5	8
2019	0	7	7
2020	3	4	7

Below are the most recent publications written about "Blood-Brain Barrier" by people in Profiles.

Yosef N, Xi Y, McCarty JH. Isolation and transcriptional characterization of mouse perivascular astrocytes. PLoS One. 2020; 15(10):e0240035.

View in: PubMed
Chen Z, Morales JE, Avci N, Guerrero PA, Rao G, Seo JH, McCarty JH. The vascular endothelial cell-expressed prion protein doppel promotes angiogenesis and blood-brain barrier development. Development. 2020 09 23; 147(18).

View in: PubMed
Akdemir ES, Huang AY, Deneen B. Astrocytogenesis: where, when, and how. F1000Res. 2020; 9.

View in: PubMed
Beccaria K, Canney M, Bouchoux G, Desseaux C, Grill J, Heimberger AB, Carpentier A. Ultrasound-induced blood-brain barrier disruption for the treatment of gliomas and other primary CNS tumors. Cancer Lett. 2020 06 01; 479:13-22.

View in: PubMed
Lee MJ, Jang Y, Han J, Kim SJ, Ju X, Lee YL, Cui J, Zhu J, Ryu MJ, Choi SY, Chung W, Heo C, Yi HS, Kim HJ, Huh YH, Chung SK, Shong M, Kweon GR, Heo JY. Endothelial-specific Crif1 deletion induces BBB maturation and disruption via the alteration of actin dynamics by impaired mitochondrial respiration. J Cereb Blood Flow Metab. 2020 07; 40(7):1546-1561.

View in: PubMed
Wang RY, da Silva Franco JF, López-Valdez J, Martins E, Sutton VR, Whitley CB, Zhang L, Cimms T, Marsden D, Jurecka A, Harmatz P. The long-term safety and efficacy of vestronidase alfa, rhGUS enzyme replacement therapy, in subjects with mucopolysaccharidosis VII. Mol Genet Metab. 2020 03; 129(3):219-227.

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Shi XX, Miao WM, Pang DW, Wu JS, Tong QS, Li JX, Luo JQ, Li WY, Du JZ, Wang J. Angiopep-2 conjugated nanoparticles loaded with doxorubicin for the treatment of primary central nervous system lymphoma. Biomater Sci. 2020 Mar 07; 8(5):1290-1297.

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Laug D, Huang TW, Huerta NAB, Huang AY, Sardar D, Ortiz-Guzman J, Carlson JC, Arenkiel BR, Kuo CT, Mohila CA, Glasgow SM, Lee HK, Deneen B. Nuclear factor I-A regulates diverse reactive astrocyte responses after CNS injury. J Clin Invest. 2019 10 01; 129(10):4408-4418.

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Uray T, Empey PE, Drabek T, Stezoski JP, Janesko-Feldman K, Jackson T, Garman RH, Kim F, Kochanek PM, Dezfulian C. Nitrite pharmacokinetics, safety and efficacy after experimental ventricular fibrillation cardiac arrest. Nitric Oxide. 2019 12 01; 93:71-77.

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Juthani R, Madajewski B, Yoo B, Zhang L, Chen PM, Chen F, Turker MZ, Ma K, Overholtzer M, Longo VA, Carlin S, Aragon-Sanabria V, Huse J, Gonen M, Zanzonico P, Rudin CM, Wiesner U, Bradbury MS, Brennan CW. Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model. Clin Cancer Res. 2020 01 01; 26(1):147-158.

View in: PubMed

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