Nucleic Acid Heteroduplexes
"Nucleic Acid Heteroduplexes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
| Descriptor ID |
D009692
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| MeSH Number(s) |
D13.444.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Heteroduplexes".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Heteroduplexes".
This graph shows the total number of publications written about "Nucleic Acid Heteroduplexes" by people in this website by year, and whether "Nucleic Acid Heteroduplexes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 3 | 2 | 5 |
| 1997 | 2 | 3 | 5 |
| 1998 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nucleic Acid Heteroduplexes" by people in Profiles.
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R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli. Nat Commun. 2013; 4:2115.
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PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis. J Biol Chem. 2013 Feb 01; 288(5):3174-83.
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Physical analyses of E. coli heteroduplex recombination products in vivo: on the prevalence of 5' and 3' patches. PLoS One. 2007 Nov 28; 2(11):e1242.
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Genetic exchange between homeologous sequences in mammalian chromosomes is averted by local homology requirements for initiation and resolution of recombination. Genetics. 2006 Sep; 174(1):135-44.
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Role of the nucleotide excision repair gene ERCC1 in formation of recombination-dependent rearrangements in mammalian cells. Nucleic Acids Res. 2000 Oct 01; 28(19):3771-8.
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Diagnosis of spinal muscular atrophy in an SMN non-deletion patient using a quantitative PCR screen and mutation analysis. J Med Genet. 1998 Aug; 35(8):674-6.
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Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res. 1998 Jun 15; 26(12):3001-5.
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Nucleotide excision repair in mammalian cells. J Biol Chem. 1997 Sep 19; 272(38):23465-8.
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Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number. Am J Hum Genet. 1997 Jun; 60(6):1411-22.
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Which DNA polymerases are used for DNA-repair in eukaryotes? Carcinogenesis. 1997 Apr; 18(4):605-10.