X Chromosome Inactivation
"X Chromosome Inactivation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females.
| Descriptor ID |
D049951
|
| MeSH Number(s) |
G05.308.203.249.970
|
| Concept/Terms |
X Chromosome Inactivation- X Chromosome Inactivation
- Chromosome Inactivation, X
- Inactivation, X Chromosome
- Lyonization
- X-Inactivation
- X Inactivation
- Inactivation, X
- X Inactivations
|
Below are MeSH descriptors whose meaning is more general than "X Chromosome Inactivation".
Below are MeSH descriptors whose meaning is more specific than "X Chromosome Inactivation".
This graph shows the total number of publications written about "X Chromosome Inactivation" by people in this website by year, and whether "X Chromosome Inactivation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 5 | 6 |
| 2007 | 0 | 4 | 4 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 4 | 6 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 3 | 3 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 4 | 2 | 6 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "X Chromosome Inactivation" by people in Profiles.
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Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes. Nat Commun. 2022 04 19; 13(1):2083.
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Molecular and clinical insights into complex genomic rearrangements related to MECP2 duplication syndrome. Eur J Med Genet. 2021 Dec; 64(12):104367.
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Abnormal X chromosome inactivation and tumor development. Cell Mol Life Sci. 2020 Aug; 77(15):2949-2958.
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Xq22 deletions and correlation with distinct neurological disease traits in females: Further evidence for a contiguous gene syndrome. Hum Mutat. 2020 01; 41(1):150-168.
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A comprehensive clinical and genetic study in 127 patients with ID in Kinshasa, DR Congo. Am J Med Genet A. 2018 09; 176(9):1897-1909.
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Autism spectrum disorder in females with ARHGEF9 alterations and a random pattern of X chromosome inactivation. Eur J Med Genet. 2019 Apr; 62(4):239-242.
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Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming. Nat Genet. 2018 02; 50(2):238-249.
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Molecular characterization of HDAC8 deletions in individuals with atypical Cornelia de Lange syndrome. J Hum Genet. 2018 Mar; 63(3):349-356.
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Xp11.22 deletions encompassing CENPVL1, CENPVL2, MAGED1 and GSPT2 as a cause of syndromic X-linked intellectual disability. PLoS One. 2017; 12(4):e0175962.
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Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Rep. 2017 01 03; 18(1):54-67.