"Sirtuin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
| Descriptor ID |
D056564
|
| MeSH Number(s) |
D08.811.277.087.520.200.650.100 D12.776.476.900.100
|
| Concept/Terms |
Sirtuin 1- Sirtuin 1
- Silent Mating Type Information Regulation 2 Homolog 1
|
Below are MeSH descriptors whose meaning is more general than "Sirtuin 1".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 1".
This graph shows the total number of publications written about "Sirtuin 1" by people in this website by year, and whether "Sirtuin 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 2 | 4 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sirtuin 1" by people in Profiles.
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SIRT1 safeguards adipogenic differentiation by orchestrating anti-oxidative responses and suppressing cellular senescence. Geroscience. 2024 02; 46(1):1107-1127.
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Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome. EBioMedicine. 2021 Dec; 74:103730.
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TFEB, SIRT1, CARM1, Beclin-1 expression and PITX2 methylation in breast cancer chemoresistance: a retrospective study. BMC Cancer. 2021 Oct 18; 21(1):1118.
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Potent PDE4 inhibitor activates AMPK and Sirt1 to induce mitochondrial biogenesis. PLoS One. 2021; 16(6):e0253269.
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SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside. JCI Insight. 2021 04 08; 6(7).
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Androgen deprivation-induced elevated nuclear SIRT1 promotes prostate tumor cell survival by reactivation of AR signaling. Cancer Lett. 2021 05 01; 505:24-36.
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Low-dose naltrexone rescues inflammation and insulin resistance associated with hyperinsulinemia. J Biol Chem. 2020 11 27; 295(48):16359-16369.
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Role of SIRT1 in HIV-associated kidney disease. Am J Physiol Renal Physiol. 2020 08 01; 319(2):F335-F344.
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SIRT1 Regulation in Ageing and Obesity. Mech Ageing Dev. 2020 06; 188:111249.
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Smooth muscle SIRT1 reprograms endothelial cells to suppress angiogenesis after ischemia. Theranostics. 2020; 10(3):1197-1212.