NIKI M. ZACHARIAS MILLWARD

TitleAssistant Professor
InstitutionMD Anderson
DepartmentCancer Systems Imaging
Address1881 East Road
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Salzillo TC, Hu J, Nguyen L, Whiting N, Lee J, Weygand J, Dutta P, Pudakalakatti S, Millward NZ, Gammon ST, Lang FF, Heimberger AB, Bhattacharya PK. Interrogating Metabolism in Brain Cancer. Magn Reson Imaging Clin N Am. 2016 Nov; 24(4):687-703. PMID: 27742110.
      Citations: 1     Fields:    Translation:Humans
    2. Rupaimoole R, Lee J, Haemmerle M, Ling H, Previs RA, Pradeep S, Wu SY, Ivan C, Ferracin M, Dennison JB, Millward NMZ, Nagaraja AS, Gharpure KM, McGuire M, Sam N, Armaiz-Pena GN, Sadaoui NC, Rodriguez-Aguayo C, Calin GA, Drapkin RI, Kovacs J, Mills GB, Zhang W, Lopez-Berestein G, Bhattacharya PK, Sood AK. Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. Cell Rep. 2015 Dec 22; 13(11):2395-2402. PMID: 26686630.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    3. Benito J, Ramirez MS, Millward NZ, Velez J, Harutyunyan KG, Lu H, Shi YX, Matre P, Jacamo R, Ma H, Konoplev S, McQueen T, Volgin A, Protopopova M, Mu H, Lee J, Bhattacharya PK, Marszalek JR, Davis RE, Bankson JA, Cortes JE, Hart CP, Andreeff M, Konopleva M. Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models. Clin Cancer Res. 2016 Apr 01; 22(7):1687-98. PMID: 26603259.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    4. Whiting N, Hu J, Shah JV, Cassidy MC, Cressman E, Millward NZ, Menter DG, Marcus CM, Bhattacharya PK. Real-Time MRI-Guided Catheter Tracking Using Hyperpolarized Silicon Particles. Sci Rep. 2015 Aug 04; 5:12842. PMID: 26239953.
      Citations: 3     Fields:    Translation:HumansAnimals
    5. Zacharias NM, Chan HR, Sailasuta N, Ross BD, Bhattacharya P. Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolarized 1-(13)C diethyl succinate. J Am Chem Soc. 2012 Jan 18; 134(2):934-43. PMID: 22146049.
      Citations: 51     Fields:    Translation:AnimalsCells
    6. Bhattacharya P, Chekmenev EY, Reynolds WF, Wagner S, Zacharias N, Chan HR, B√ľnger R, Ross BD. Parahydrogen-induced polarization (PHIP) hyperpolarized MR receptor imaging in vivo: a pilot study of 13C imaging of atheroma in mice. NMR Biomed. 2011 Oct; 24(8):1023-8. PMID: 21538638.
      Citations: 45     Fields:    Translation:Animals
    7. Eastwood AL, Blum AP, Zacharias NM, Dougherty DA. A selenide-based approach to photochemical cleavage of peptide and protein backbones at engineered backbone esters. J Org Chem. 2009 Dec 04; 74(23):9241-4. PMID: 19902952.
      Citations: 2     Fields:    Translation:Cells
    8. Suto MJ, Zacharias N. Neuronal nicotinic acetylcholine receptors as drug targets. Expert Opin Ther Targets. 2004 Apr; 8(2):61-4. PMID: 15102549.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    9. Petersson EJ, Brandt GS, Zacharias NM, Dougherty DA, Lester HA. Caging proteins through unnatural amino acid mutagenesis. Methods Enzymol. 2003; 360:258-73. PMID: 12622154.
      Citations: 5     Fields:    Translation:AnimalsCells
    10. Beene DL, Brandt GS, Zhong W, Zacharias NM, Lester HA, Dougherty DA. Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine. Biochemistry. 2002 Aug 13; 41(32):10262-9. PMID: 12162741.
      Citations: 81     Fields:    Translation:AnimalsCells
    11. Zacharias N, Dougherty DA. Cation-pi interactions in ligand recognition and catalysis. Trends Pharmacol Sci. 2002 Jun; 23(6):281-7. PMID: 12084634.
      Citations: 84     Fields:    Translation:Cells
    12. Li L, Zhong W, Zacharias N, Gibbs C, Lester HA, Dougherty DA. The tethered agonist approach to mapping ion channel proteins--toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor. Chem Biol. 2001 Jan; 8(1):47-58. PMID: 11182318.
      Citations: 11     Fields:    Translation:AnimalsCells
    13. Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models. BMC Cancer. 16.
    14. Hypoxia-activated prodrug TH-302 targets hypoxic bone marrow niches in preclinical leukemia models. Clinical Cancer Research. 22:1687-1698.
    15. Interrogating Metabolism in Brain Cancer. Magnetic Resonance Imaging Clinics of North America. 24:687-703.
    16. Role of Increased n-acetylaspartate Levels in Cancer. Journal of the National Cancer Institute. 108.
    17. Developing hyperpolarized silicon particles for advanced biomedical imaging applications.
    18. Bio-interfacial magnetic resonance imaging of hyperpolarized contrast agents for metabolic flux interrogation in vivo. Journal of Industrial and Engineering Chemistry. 36:224-228.
    19. Unnatural Amino Acids as Probes of Ion Channel Structure - Function and Pharmacology. 59-77.
    20. Developing hyperpolarized silicon particles for in vivo MRI targeting of ovarian cancer. Journal of Medical Imaging. 3.
    21. Improved synthesis of the Boc and Fmoc derivatives of 4-(2'-aminoethyl)-6-dibenzofuranpropionic acid. Journal of Organic Chemistry. 62:2259-2262.
    22. Real-Time MRI-Guided Catheter Tracking Using Hyperpolarized Silicon Particles. Scientific Reports. 5.
    23. Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. Cell Reports. 13:2395-2402.
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