| Item Type | Name |
|
Academic Article
|
Secreted growth factors from estrogen receptor-negative human breast cancer do not support growth of estrogen receptor-positive breast cancer in the nude mouse model.
|
|
Academic Article
|
Molecular aspects of estrogen receptor variants in breast cancer.
|
|
Academic Article
|
Coexpression of wild-type and variant oestrogen receptor mRNAs in a panel of human breast cancer cell lines.
|
|
Academic Article
|
Mechanisms of action of antiestrogens.
|
|
Academic Article
|
Measurement of steroid hormone receptors in breast cancer patients on tamoxifen.
|
|
Academic Article
|
An exon 5 deletion variant of the estrogen receptor frequently coexpressed with wild-type estrogen receptor in human breast cancer.
|
|
Academic Article
|
Estrogen receptor mutagenesis and hormone resistance.
|
|
Academic Article
|
Tamoxifen resistance in breast cancer.
|
|
Academic Article
|
Differential expression of wild-type and variant ER mRNAs by stocks of MCF-7 breast cancer cells may account for differences in estrogen responsiveness.
|
|
Academic Article
|
An estrogen receptor mutant with strong hormone-independent activity from a metastatic breast cancer.
|
|
Academic Article
|
MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen.
|
|
Academic Article
|
Expression of estrogen receptor variants.
|
|
Academic Article
|
The small heat shock protein HSP27 is not an independent prognostic marker in axillary lymph node-negative breast cancer patients.
|
|
Academic Article
|
Auto-regulation of the estrogen receptor promoter.
|
|
Academic Article
|
Estrogen receptor mutations in breast cancer.
|
|
Academic Article
|
Alterations in the estrogen receptor alpha mRNA in the breast tumors of African American women.
|
|
Academic Article
|
The role of the estrogen receptor in tumor progression.
|
|
Academic Article
|
Relationship of clone 4 estrogen receptor variant messenger RNA expression to some known prognostic variables in human breast cancer.
|
|
Academic Article
|
Production and characterization of an estrogen receptor beta subtype-specific mouse monoclonal antibody.
|
|
Academic Article
|
Estrogen receptor and breast cancer.
|
|
Academic Article
|
Multiple splicing variants of the estrogen receptor are present in individual human breast tumors.
|
|
Academic Article
|
A point mutation in the human estrogen receptor gene is associated with the expression of an abnormal estrogen receptor mRNA containing a 69 novel nucleotide insertion.
|
|
Academic Article
|
Prognostic factors and variant estrogen receptor RNAs in clinical breast cancer.
|
|
Academic Article
|
Novel nuclear matrix protein HET binds to and influences activity of the HSP27 promoter in human breast cancer cells.
|
|
Academic Article
|
A hypersensitive estrogen receptor-alpha mutation in premalignant breast lesions.
|
|
Academic Article
|
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity.
|
|
Academic Article
|
Statistical analysis of array expression data as applied to the problem of tamoxifen resistance.
|
|
Academic Article
|
Where is the lesion in hormone-independent breast cancer?
|
|
Academic Article
|
Expression of wild-type estrogen receptor beta and variant isoforms in human breast cancer.
|
|
Academic Article
|
Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors.
|
|
Academic Article
|
Tamoxifen-bound estrogen receptor (ER) strongly interacts with the nuclear matrix protein HET/SAF-B, a novel inhibitor of ER-mediated transactivation.
|
|
Academic Article
|
Estrogen receptor variants.
|
|
Academic Article
|
Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity.
|
|
Academic Article
|
Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo.
|
|
Academic Article
|
Abnormal estrogen receptor in clinical breast cancer.
|
|
Academic Article
|
Consensus statement: Expedition Inspiration fund for breast cancer research meeting 2002.
|
|
Academic Article
|
Estrogen receptor: current understanding of its activation and modulation.
|
|
Academic Article
|
Estrogen receptor alpha-negative breast cancer tissues express significant levels of estrogen-independent transcription factors, ERbeta1 and ERbeta5: potential molecular targets for chemoprevention.
|
|
Academic Article
|
The role of estrogen receptors in breast cancer metastasis.
|
|
Academic Article
|
HER-2/neu amplification predicts poor survival in node-positive breast cancer.
|
|
Academic Article
|
Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis.
|
|
Academic Article
|
Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer.
|
|
Academic Article
|
Breast cancer patients with progesterone receptor PR-A-rich tumors have poorer disease-free survival rates.
|
|
Academic Article
|
Regulation of the estrogen receptor alpha minimal promoter by Sp1, USF-1 and ERalpha.
|
|
Academic Article
|
Clinical relevance of estrogen receptor variants in breast cancer.
|
|
Academic Article
|
Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer.
|
|
Academic Article
|
Progesterone receptor B recruits a repressor complex to a half-PRE site of the estrogen receptor alpha gene promoter.
|
|
Academic Article
|
Targeting the estrogen receptor in clinical breast cancer.
|
|
Academic Article
|
Accelerated mammary maturation and differentiation, and delayed MMTVneu-induced tumorigenesis of K303R mutant ERalpha transgenic mice.
|
|
Academic Article
|
Estrogen receptor mutations and changes in downstream gene expression and signaling.
|
|
Academic Article
|
Estrogen receptor gene methylation in human breast tumors.
|
|
Academic Article
|
Negative regulation of estrogen receptor alpha transactivation functions by LIM domain only 4 protein.
|
|
Academic Article
|
Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer.
|
|
Academic Article
|
Loss of Rho GDIa and resistance to tamoxifen via effects on estrogen receptor a.
|
|
Academic Article
|
Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor alpha gene expression via p38MAPK/CK2 signaling in human breast cancer cells.
|
|
Academic Article
|
Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes.
|
|
Academic Article
|
Estrogen receptor beta binds Sp1 and recruits a corepressor complex to the estrogen receptor alpha gene promoter.
|
|
Academic Article
|
In vitro mechanism for downregulation of ER-a expression by epigallocatechin gallate in ER+/PR+ human breast cancer cells.
|
|
Academic Article
|
Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells.
|
|
Academic Article
|
Variant human breast tumor estrogen receptor with constitutive transcriptional activity.
|
|
Academic Article
|
Estrogen receptors in resistance to hormone therapy.
|
|
Academic Article
|
Association between the estrogen receptor alpha A908G mutation and outcomes in invasive breast cancer.
|
|
Academic Article
|
Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305.
|
|
Academic Article
|
Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway.
|
|
Academic Article
|
Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity.
|
|
Academic Article
|
Identification of a novel estrogen receptor-alpha variant and its upstream splicing regulator.
|
|
Academic Article
|
Sensitive detection of estrogen receptor RNA by polymerase chain reaction assay.
|
|
Academic Article
|
Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells.
|
|
Academic Article
|
Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression.
|
|
Academic Article
|
Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor.
|
|
Academic Article
|
A phase II neoadjuvant trial of anastrozole, fulvestrant, and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer.
|
|
Academic Article
|
Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells.
|
|
Academic Article
|
Induction of the estrogen-regulated "24K" protein by heat shock.
|
|
Academic Article
|
Mechanisms of tamoxifen resistance.
|
|
Academic Article
|
Estrogen receptor variants in breast cancer.
|
|
Academic Article
|
The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain.
|
|
Academic Article
|
The importance of normal and abnormal oestrogen receptor in breast cancer.
|
|
Academic Article
|
Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions.
|
|
Academic Article
|
Abnormal oestrogen receptor in clinical breast cancer.
|
|
Academic Article
|
Estrogen receptor variants in clinical breast cancer.
|
|
Academic Article
|
Insights into the role of progesterone receptors in breast cancer.
|
|
Academic Article
|
Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance.
|
|
Academic Article
|
Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells.
|
|
Academic Article
|
Inhibition of mammary tumorigenesis by estrogen and progesterone in genetically engineered mice.
|
|
Academic Article
|
G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells.
|
|
Academic Article
|
A hypersensitive estrogen receptor alpha mutation that alters dynamic protein interactions.
|
|
Academic Article
|
BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.
|
|
Academic Article
|
Estrogen receptor expression in human breast cancer associated with an estrogen receptor gene restriction fragment length polymorphism.
|
|
Concept
|
Estrogen Receptor Modulators
|
|
Concept
|
Estrogen Antagonists
|
|
Concept
|
Estrogen Receptor beta
|
|
Concept
|
Receptors, Estrogen
|
|
Concept
|
Estrogens
|
|
Concept
|
Selective Estrogen Receptor Modulators
|
|
Concept
|
Estrogen Receptor alpha
|
|
Academic Article
|
Hormone Action and Clinical Significance of the Estrogen Receptor a.
|
|
Academic Article
|
Tamoxifen regulates cell fate through mitochondrial estrogen receptor beta in breast cancer.
|
|
Academic Article
|
Metastasis tumor-associated protein 2 enhances metastatic behavior and is associated with poor outcomes in estrogen receptor-negative breast cancer.
|
|
Academic Article
|
Estrogen receptor (ER) a mutations in breast cancer: hidden in plain sight.
|
|
Academic Article
|
Tamoxifen through GPER upregulates aromatase expression: a novel mechanism sustaining tamoxifen-resistant breast cancer cell growth.
|
|
Academic Article
|
AR collaborates with ERa in aromatase inhibitor-resistant breast cancer.
|
|
Academic Article
|
Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERa-positive breast cancer.
|
|
Academic Article
|
ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling.
|
|
Academic Article
|
Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion.
|
|
Academic Article
|
Erratum to: Estrogen receptor beta binds Sp1 and recruits a corepressor complex to the estrogen receptor alpha gene promoter.
|
|
Academic Article
|
ESR1 Mutations in Cell-Free DNA of Breast Cancer: Predictive "Tip of the Iceberg".
|
|
Academic Article
|
Estrogen receptors in breast and bone: from virtue of remodeling to vileness of metastasis.
|
|
Academic Article
|
Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines.
|
|
Academic Article
|
Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets.
|
|
Academic Article
|
The Impact of ESR1 Mutations on the Treatment of Metastatic Breast Cancer.
|
|
Concept
|
Estrogen Receptor Antagonists
|
|
Academic Article
|
ESR1 mutations in breast cancer.
|
|
Academic Article
|
Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity.
|
|
Grant
|
MUTATIONS IN INDIVIDUAL BREAST CANCERS--PCR SEQUENCING
|
|
Grant
|
Integration of Predictive Biomarkers of Hormone Resistance in Breast Cancer
|
|
Grant
|
MECHANISMS OF AR-ER COLLABORATION IN HORMONE RESISTANCE AND METASTASIS OF BREAST CANCER
|
|
Academic Article
|
RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer.
|
|
Academic Article
|
Hormonal modulation of ESR1 mutant metastasis.
|
|
Academic Article
|
ESR1 mutations and therapeutic resistance in metastatic breast cancer: progress and remaining challenges.
|