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O'MALLEY, BERT

One or more keywords matched the following items that are connected to O'MALLEY, BERT

Item Type	Name
Academic Article	Hierarchical affinities and a bipartite interaction model for estrogen receptor isoforms and full-length steroid receptor coactivator (SRC/p160) family members.
Academic Article	Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation.
Academic Article	The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors.
Academic Article	A life-long search for the molecular pathways of steroid hormone action.
Academic Article	Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor.
Academic Article	Acute disruption of select steroid receptor coactivators prevents reproductive behavior in rats and unmasks genetic adaptation in knockout mice.
Academic Article	Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland.
Academic Article	Coregulator function: a key to understanding tissue specificity of selective receptor modulators.
Academic Article	A repressive role for prohibitin in estrogen signaling.
Academic Article	Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover.
Academic Article	Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice.
Academic Article	Pituitary adenylate cyclase-activating peptide: a pivotal modulator of steroid-induced reproductive behavior in female rodents.
Academic Article	Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation.
Academic Article	An estrogen receptor alpha activity indicator model in mice.
Academic Article	Splicing potentiation by growth factor signals via estrogen receptor phosphorylation.
Academic Article	Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).
Academic Article	The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome.
Academic Article	Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta.
Academic Article	Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo.
Academic Article	Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice.
Academic Article	Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.
Academic Article	WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors.
Academic Article	Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation.
Academic Article	Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse.
Academic Article	Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1.
Academic Article	Maturation of microRNA is hormonally regulated by a nuclear receptor.
Academic Article	Global characterization of transcriptional impact of the SRC-3 coregulator.
Academic Article	ERasing breast cancer resistance through the kinome.
Academic Article	Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing.
Academic Article	Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins.
Academic Article	AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice.
Academic Article	Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator.
Academic Article	Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice.
Academic Article	Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor.
Academic Article	Selective estrogen-receptor modulators and antihormonal resistance in breast cancer.
Academic Article	OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity.
Academic Article	Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM.
Academic Article	Estrogen-regulated prohibitin is required for mouse uterine development and adult function.
Academic Article	Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy.
Academic Article	Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1.
Academic Article	Elwood V. Jensen (1920-2012): father of the nuclear receptors.
Concept	Estrogen Replacement Therapy
Concept	Estrogen Antagonists
Concept	Estrogens, Conjugated (USP)
Concept	Estrogen Receptor beta
Concept	Receptors, Estrogen
Concept	Estrogens
Concept	Selective Estrogen Receptor Modulators
Concept	Estrogen Receptor alpha
Academic Article	Proteomic analysis of coregulators bound to ERa on DNA and nucleosomes reveals coregulator dynamics.
Academic Article	The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis.
Academic Article	E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity.
Academic Article	An epigenomic approach to therapy for tamoxifen-resistant breast cancer.
Academic Article	Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function.
Academic Article	AR collaborates with ERa in aromatase inhibitor-resistant breast cancer.
Academic Article	Nuclear receptor modulation--role of coregulators in selective estrogen receptor modulator (SERM) actions.
Academic Article	Structure of a biologically active estrogen receptor-coactivator complex on DNA.
Academic Article	CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC.
Academic Article	Estrogen receptor-a: molecular mechanisms and interactions with the ubiquitin proteasome system.
Academic Article	The Dual Estrogen Receptor a Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.
Academic Article	Estrogen Receptor ? Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis.
Academic Article	Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug.
Academic Article	Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.
Academic Article	Structural and Functional Impacts of ER Coactivator Sequential Recruitment.
Academic Article	Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization.
Academic Article	Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets.
Academic Article	SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription.
Grant	GF/STEROID RECEPTOR INTERACTION IN BREAST CANCER IN VIVO
Grant	Sex Hormone Receptor Components and the Cell Genome
Grant	Reproductive Hormones - Biological and Molecular Actions
Grant	Small molecule Inhibitors of steroid receptor coactivator to treat breast cancer
Concept	Estrogen Receptor Antagonists
Academic Article	Genomic Function of Estrogen Receptor ? in Endometriosis.
Academic Article	Drug-induced PD-L1 expression and cell stress response in breast cancer cells can be balanced by drug combination.
Academic Article	90 YEARS OF PROGESTERONE: Reminiscing on the origins of the field of progesterone and estrogen receptor action.
Academic Article	Cell lineage tracing links ERa loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype.
Academic Article	Oleuropein suppresses endometriosis progression and improves the fertility of mice with endometriosis.
Academic Article	A GREB1-steroid receptor feedforward mechanism governs differential GREB1 action in endometrial function and endometriosis.

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