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SCHIFF, RACHEL

One or more keywords matched the following items that are connected to SCHIFF, RACHEL

Item Type	Name
Academic Article	Dominant-negative nuclear receptor corepressor relieves transcriptional inhibition of retinoic acid receptor but does not alter the agonist/antagonist activities of the tamoxifen-bound estrogen receptor.
Academic Article	Advances in breast cancer treatment and prevention: preclinical studies on aromatase inhibitors and new selective estrogen receptor modulators (SERMs).
Academic Article	Expression of wild-type estrogen receptor beta and variant isoforms in human breast cancer.
Academic Article	Proceedings of the Third International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement.
Academic Article	Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance.
Academic Article	Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo.
Academic Article	Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer.
Academic Article	Aromatase inhibitors: future directions.
Academic Article	Estrogen receptor: current understanding of its activation and modulation.
Academic Article	Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: implicated role of growth factor signaling and estrogen receptor coregulators.
Academic Article	Can biomarkers direct the optimal use of aromatase inhibitors versus selective estrogen receptor modulators?
Academic Article	The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth.
Academic Article	Inhibition of AP-1 transcription factor causes blockade of multiple signal transduction pathways and inhibits breast cancer growth.
Academic Article	Breast cancer endocrine resistance: how growth factor signaling and estrogen receptor coregulators modulate response.
Academic Article	Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer.
Academic Article	Treatment of human epidermal growth factor receptor 2-overexpressing breast cancer xenografts with multiagent HER-targeted therapy.
Academic Article	Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer.
Academic Article	Estrogen-receptor biology: continuing progress and therapeutic implications.
Academic Article	Sphingosine kinase 1 induces tolerance to human epidermal growth factor receptor 2 and prevents formation of a migratory phenotype in response to sphingosine 1-phosphate in estrogen receptor-positive breast cancer cells.
Academic Article	Endocrinology and hormone therapy in breast cancer: new insight into estrogen receptor-alpha function and its implication for endocrine therapy resistance in breast cancer.
Academic Article	Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action.
Academic Article	Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase.
Academic Article	Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations.
Academic Article	Cytoplasmic estrogen receptor in breast cancer.
Academic Article	Estrogen receptor-positive, progesterone receptor-negative breast cancer: association with growth factor receptor expression and tamoxifen resistance.
Academic Article	Resistance to endocrine therapy in breast cancer: exploiting estrogen receptor/growth factor signaling crosstalk.
Academic Article	Unraveling the mechanisms of endocrine resistance in breast cancer: new therapeutic opportunities.
Academic Article	PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells.
Academic Article	Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer.
Academic Article	Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance.
Academic Article	Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function.
Academic Article	Development of resistance to targeted therapies transforms the clinically associated molecular profile subtype of breast tumor xenografts.
Academic Article	More on FOX News: FOXA1 on the horizon of estrogen receptor function and endocrine response.
Academic Article	?1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib.
Academic Article	Mechanisms of endocrine resistance in breast cancer.
Academic Article	SGK3 is associated with estrogen receptor expression in breast cancer.
Academic Article	Upregulation of mucin4 in ER-positive/HER2-overexpressing breast cancer xenografts with acquired resistance to endocrine and HER2-targeted therapies.
Academic Article	Multicenter phase II study of neoadjuvant lapatinib and trastuzumab with hormonal therapy and without chemotherapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer: TBCRC 006.
Academic Article	Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters.
Academic Article	Estrogen-mediated down-regulation of E-cadherin in breast cancer cells.
Academic Article	Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer.
Academic Article	Upregulation of PKC-delta contributes to antiestrogen resistance in mammary tumor cells.
Academic Article	Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy.
Academic Article	Endocrine responsiveness: understanding how progesterone receptor can be used to select endocrine therapy.
Academic Article	The dynamics of estrogen receptor status in breast cancer: re-shaping the paradigm.
Academic Article	Molecular profiles of progesterone receptor loss in human breast tumors.
Academic Article	Post-transcriptional regulation of chemokine receptor CXCR4 by estrogen in HER2 overexpressing, estrogen receptor-positive breast cancer cells.
Academic Article	Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer.
Academic Article	Somatic expression of PyMT or activated ErbB2 induces estrogen-independent mammary tumorigenesis.
Academic Article	Gefitinib or placebo in combination with tamoxifen in patients with hormone receptor-positive metastatic breast cancer: a randomized phase II study.
Concept	Estrogen Receptor Modulators
Concept	Estrogen Antagonists
Concept	Estrogen Receptor beta
Concept	Receptors, Estrogen
Concept	Estrogens
Concept	Selective Estrogen Receptor Modulators
Concept	Estrogen Receptor alpha
Academic Article	Biology and therapeutic potential of PI3K signaling in ER+/HER2-negative breast cancer.
Academic Article	Metastasis dormancy in estrogen receptor-positive breast cancer.
Academic Article	MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
Academic Article	Therapeutic potential of the dual EGFR/HER2 inhibitor AZD8931 in circumventing endocrine resistance.
Academic Article	Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancer.
Academic Article	Bidirectional Crosstalk between the Estrogen Receptor and Human Epidermal Growth Factor Receptor 2 Signaling Pathways in Breast Cancer: Molecular Basis and Clinical Implications.
Academic Article	An epigenomic approach to therapy for tamoxifen-resistant breast cancer.
Academic Article	Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers.
Academic Article	Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase.
Academic Article	Targeting HER2 for the treatment of breast cancer.
Academic Article	Resistance to Anti-HER2 Therapies in Breast Cancer.
Academic Article	Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy.
Academic Article	The changing role of ER in endocrine resistance.
Academic Article	ESR1 mutations?a mechanism for acquired endocrine resistance in breast cancer.
Academic Article	Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance.
Academic Article	Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers.
Academic Article	FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer.
Academic Article	Identification of MYST3 as a novel epigenetic activator of ERa frequently amplified in breast cancer.
Academic Article	The Evolving Role of the Estrogen Receptor Mutations in Endocrine Therapy-Resistant Breast Cancer.
Academic Article	HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer.
Academic Article	Embryonic transcription factor SOX9 drives breast cancer endocrine resistance.
Academic Article	De-escalation of treatment in HER2-positive breast cancer: Determinants of response and mechanisms of resistance.
Academic Article	Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis.
Academic Article	The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance.
Academic Article	Temporal dynamic reorganization of 3D chromatin architecture in hormone-induced breast cancer and endocrine resistance.
Academic Article	TBCRC023: A Randomized Phase II Neoadjuvant Trial of Lapatinib Plus Trastuzumab Without Chemotherapy for 12 versus 24 Weeks in Patients with HER2-Positive Breast Cancer.
Academic Article	Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity.
Academic Article	Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance.
Academic Article	Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance.
Academic Article	Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer.
Academic Article	Therapeutic Targeting of Nemo-like Kinase in Primary and Acquired Endocrine-resistant Breast Cancer.
Academic Article	The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells.
Academic Article	Management of hormone receptor-positive, human epidermal growth factor 2-negative metastatic breast cancer.
Academic Article	Interferon Signaling in Estrogen Receptor-positive Breast Cancer: A Revitalized Topic.
Academic Article	NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer.
Academic Article	Elacestrant and the Promise of Oral SERDs.
Academic Article	A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer.
Academic Article	Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer.

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Estrogens