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OSBORNE, C
One or more keywords matched the following items that are connected to OSBORNE, C
Item TypeName
Academic Article Secreted growth factors from estrogen receptor-negative human breast cancer do not support growth of estrogen receptor-positive breast cancer in the nude mouse model.
Academic Article Multiple estrogen receptor assays in human breast cancer.
Academic Article Measurement of steroid hormone receptors in breast cancer patients on tamoxifen.
Academic Article Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer.
Academic Article Tumor biologic factors and breast cancer prognosis among white, Hispanic, and black women in the United States.
Academic Article The small heat shock protein HSP27 is not an independent prognostic marker in axillary lymph node-negative breast cancer patients.
Academic Article Time-dependence of hazard ratios for prognostic factors in primary breast cancer.
Academic Article Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes.
Academic Article Estrogen receptor (ER) and progesterone receptor (PgR), by ligand-binding assay compared with ER, PgR and pS2, by immuno-histochemistry in predicting response to tamoxifen in metastatic breast cancer: a Southwest Oncology Group Study.
Academic Article Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth.
Academic Article Multicenter phase II study of oral bexarotene for patients with metastatic breast cancer.
Academic Article Dominant-negative nuclear receptor corepressor relieves transcriptional inhibition of retinoic acid receptor but does not alter the agonist/antagonist activities of the tamoxifen-bound estrogen receptor.
Academic Article Statistical analysis of array expression data as applied to the problem of tamoxifen resistance.
Academic Article Cross-talk between estrogen receptor and growth factor pathways as a molecular target for overcoming endocrine resistance.
Academic Article Tamoxifen-bound estrogen receptor (ER) strongly interacts with the nuclear matrix protein HET/SAF-B, a novel inhibitor of ER-mediated transactivation.
Academic Article HER-2 amplification, HER-1 expression, and tamoxifen response in estrogen receptor-positive metastatic breast cancer: a southwest oncology group study.
Academic Article Selective estrogen receptor modulators: structure, function, and clinical use.
Academic Article Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo.
Academic Article Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement.
Academic Article Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer.
Academic Article Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma: a prospectively planned combined survival analysis of two multicenter trials.
Academic Article Aromatase inhibitors: future directions.
Academic Article Estrogen receptor: current understanding of its activation and modulation.
Academic Article Scaffold attachment factor SAFB1 suppresses estrogen receptor alpha-mediated transcription in part via interaction with nuclear receptor corepressor.
Academic Article Breast tumors that overexpress nuclear metastasis-associated 1 (MTA1) protein have high recurrence risks but enhanced responses to systemic therapies.
Academic Article Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: implicated role of growth factor signaling and estrogen receptor coregulators.
Academic Article Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in postmenopausal women: a prospective combined analysis of two multicenter trials.
Academic Article The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth.
Academic Article Inhibition of AP-1 transcription factor causes blockade of multiple signal transduction pathways and inhibits breast cancer growth.
Academic Article The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer.
Academic Article Disruption of estrogen receptor DNA-binding domain and related intramolecular communication restores tamoxifen sensitivity in resistant breast cancer.
Academic Article Breast cancer endocrine resistance: how growth factor signaling and estrogen receptor coregulators modulate response.
Academic Article Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer.
Academic Article Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer.
Academic Article Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer.
Academic Article Estrogen-receptor biology: continuing progress and therapeutic implications.
Academic Article Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial.
Academic Article Chemoendocrine therapy for premenopausal women with axillary lymph node-positive, steroid hormone receptor-positive breast cancer: results from INT 0101 (E5188).
Academic Article American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version).
Academic Article Endocrinology and hormone therapy in breast cancer: new insight into estrogen receptor-alpha function and its implication for endocrine therapy resistance in breast cancer.
Academic Article Optimizing chemotherapy-free survival for the ER/HER2-positive metastatic breast cancer patient.
Academic Article Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase.
Academic Article Hormone receptor status of a contralateral breast cancer is independent of the receptor status of the first primary in patients not receiving adjuvant tamoxifen.
Academic Article Breast Cancer: Blocking both driver and escape pathways improves outcomes.
Academic Article Estrogen receptor-positive, progesterone receptor-negative breast cancer: association with growth factor receptor expression and tamoxifen resistance.
Academic Article Is there a role for adjuvant tamoxifen in progesterone receptor-positive breast cancer? An in silico clinical trial.
Academic Article Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer.
Academic Article Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function.
Academic Article Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial.
Academic Article Adjuvant chemotherapy and timing of tamoxifen in postmenopausal patients with endocrine-responsive, node-positive breast cancer: a phase 3, open-label, randomised controlled trial.
Academic Article American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.
Academic Article American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.
Academic Article Mechanisms of endocrine resistance in breast cancer.
Academic Article Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor.
Academic Article Inhibition of estrogen-induced breast cancer cell proliferation by reduction in autocrine transforming growth factor alpha expression.
Academic Article Mechanisms of tamoxifen resistance.
Academic Article Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo.
Academic Article Significance of axillary lymph node metastasis in primary breast cancer.
Academic Article HET/SAF-B overexpression causes growth arrest and multinuclearity and is associated with aneuploidy in human breast cancer.
Academic Article High rates of loss of heterozygosity on chromosome 19p13 in human breast cancer.
Academic Article Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial.
Academic Article Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer databases.
Academic Article Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters.
Academic Article Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer.
Academic Article Effect of epidermal growth factor receptor inhibitor on development of estrogen receptor-negative mammary tumors.
Academic Article Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action.
Academic Article Insights into the role of progesterone receptors in breast cancer.
Academic Article Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy.
Academic Article Endocrine responsiveness: understanding how progesterone receptor can be used to select endocrine therapy.
Academic Article Molecular profiles of progesterone receptor loss in human breast tumors.
Academic Article Breast cancer incidence in the randomized PEARL trial of lasofoxifene in postmenopausal osteoporotic women.
Academic Article Gefitinib or placebo in combination with tamoxifen in patients with hormone receptor-positive metastatic breast cancer: a randomized phase II study.
Concept Estrogen Receptor Modulators
Concept Estrogen Antagonists
Concept Estrogen Receptor beta
Concept Receptors, Estrogen
Concept Estrogens
Concept Selective Estrogen Receptor Modulators
Concept Estrogen Receptor alpha
Academic Article A critical review why assessment of steroid hormone receptors in breast cancer should be quantitative.
Academic Article Cancer Res
Academic Article AACR
Academic Article SABCS
Academic Article In vitro model systems for the study of hormone-dependent human breast cancer.
Academic Article Current use of steroid hormone receptor assays in the treatment of breast cancer.
Academic Article Therapy for cancer of the breast. Current status of steroid hormone receptors.
Academic Article The use of stero?d hormone receptors in the treatment of human breast cancer: a review.
Academic Article Hormone receptors in primary and advanced breast cancer.
Academic Article The value of estrogen and progesterone receptors in the treatment of breast cancer.
Academic Article Modern approaches to the treatment of breast cancer.
Academic Article Steroid hormone receptors in the management of human breast cancer.
Academic Article Correlation of primary breast cancer histopathology and estrogen receptor content.
Academic Article Combined chemo-hormonal therapy in breast cancer: a hypothesis.
Academic Article Adjuvant therapy for stage II, estrogen receptor negative breast cancer.
Academic Article Estrogen receptor, a marker for human breast cancer differentiation and patient prognosis.
Academic Article Steroid hormone receptors and carcinoma of the breast.
Academic Article Effects of tamoxifen on human breast cancer cell cycle kinetics: accumulation of cells in early G1 phase.
Academic Article Correlations between estrogen receptor, progesterone receptor, and patient characteristics in human breast cancer.
Academic Article Human breast cancer cell cycle synchronization by estrogens and antiestrogens in culture.
Academic Article Hormone receptors in the management of breast cancer.
Academic Article Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice.
Academic Article Heterogeneity in hormone receptor status in primary and metastatic breast cancer.
Academic Article A randomized trial of doxorubicin, mitoxantrone and bisantrene in advanced breast cancer (a South West Oncology Group Study).
Academic Article Adjuvant therapy for breast cancer with positive axillary nodes designed according to estrogen receptor status.
Academic Article Adjuvant therapy for breast cancer with positive axillary nodes designed according to estrogen receptor status.
Academic Article Endocrine therapy testing of human breast cancers in the soft agar clonogenic assay.
Academic Article Biological differences among MCF-7 human breast cancer cell lines from different laboratories.
Academic Article Human breast cancer in the athymic nude mouse: cytostatic effects of long-term antiestrogen therapy.
Academic Article Survival from first recurrence: relative importance of prognostic factors in 1,015 breast cancer patients.
Academic Article Resistance to endocrine therapy. A panel discussion.
Academic Article Transforming growth factor beta: potential autocrine growth inhibitor of estrogen receptor-negative human breast cancer cells.
Academic Article Blockade of the epidermal growth factor receptor inhibits transforming growth factor alpha-induced but not estrogen-induced growth of hormone-dependent human breast cancer.
Academic Article Antagonism of chemotherapy-induced cytotoxicity for human breast cancer cells by antiestrogens.
Academic Article Efficacy of adjuvant chemotherapy in high-risk node-negative breast cancer. An intergroup study.
Academic Article Adjuvant therapy in node-negative breast cancer. A panel discussion.
Academic Article Effects of c-myc overexpression on the growth characteristics of MCF-7 human breast cancer cells.
Academic Article Therapy in premenopausal women with advanced, oestrogen positive or/and progesterone positive breast cancer: surgical oophorectomy versus the LHRH analogue, Zoladex.
Academic Article Megestrol acetate in breast cancer--a panel discussion.
Academic Article Insulin-like growth factor binding protein secretion by breast carcinoma cell lines: correlation with estrogen receptor status.
Academic Article Regulation of breast cancer growth by insulin-like growth factors.
Academic Article Growth factors as mediators of estrogen/antiestrogen action in human breast cancer cells.
Academic Article Acquired tamoxifen resistance: correlation with reduced breast tumor levels of tamoxifen and isomerization of trans-4-hydroxytamoxifen.
Academic Article Inhibition of breast cancer cell growth in vitro by a tyrosine kinase inhibitor.
Academic Article Chemotherapy versus observation in high-risk node-negative breast cancer patients.
Academic Article Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu.
Academic Article Proportional hazards and recursive partitioning and amalgamation analyses of the Southwest Oncology Group node-positive adjuvant CMFVP breast cancer data base: a pilot study.
Academic Article One versus 2 years of CMFVP adjuvant chemotherapy in axillary node-positive and estrogen receptor-negative patients: a Southwest Oncology Group study.
Academic Article Mechanisms for tamoxifen resistance in breast cancer: possible role of tamoxifen metabolism.
Academic Article Recruitment with high physiological doses of estradiol preceding chemotherapy: flow cytometric and therapeutic results in women with locally advanced breast cancers--a Southwest Oncology Group study.
Academic Article Adjuvant CMFVP versus tamoxifen versus concurrent CMFVP and tamoxifen for postmenopausal, node-positive, and estrogen receptor-positive breast cancer patients: a Southwest Oncology Group study.
Academic Article Pure antiestrogens. The most important advance in the endocrine therapy of breast cancer since 1896.
Academic Article Adjuvant chemotherapy plus tamoxifen compared with tamoxifen alone for postmenopausal breast cancer: meta-analysis of quality-adjusted survival.
Academic Article Adjuvant CMFVP versus adjuvant CMFVP plus ovariectomy for premenopausal, node-positive, and estrogen receptor-positive breast cancer patients: a Southwest Oncology Group study.
Academic Article bcl-2, p53, and response to tamoxifen in estrogen receptor-positive metastatic breast cancer: a Southwest Oncology Group study.
Academic Article Comparison of estrogen receptor DNA binding in untreated and acquired antiestrogen-resistant human breast tumors.
Academic Article Prediction of response to neoadjuvant chemoendocrine therapy in primary breast carcinomas.
Academic Article Cytological evaluation of biological prognostic markers from primary breast carcinomas.
Academic Article Oestrogen receptors and breast cancer.
Academic Article Megestrol acetate and aminoglutethimide/hydrocortisone in sequence or in combination as second-line endocrine therapy of estrogen receptor-positive metastatic breast cancer: a Southwest Oncology Group phase III trial.
Academic Article Multicenter randomized clinical trial of goserelin versus surgical ovariectomy in premenopausal patients with receptor-positive metastatic breast cancer: an intergroup study.
Academic Article HER-2 expression and response to tamoxifen in estrogen receptor-positive breast cancer: a Southwest Oncology Group Study.
Academic Article Heat shock proteins hsp27 and hsp70: lack of correlation with response to tamoxifen and clinical course of disease in estrogen receptor-positive metastatic breast cancer (a Southwest Oncology Group Study).
Academic Article Steroid hormone receptors in breast cancer management.
Academic Article Aromatase inhibitors in relation to other forms of endocrine therapy for breast cancer.
Academic Article Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer.
Academic Article Biologic markers as predictors of clinical outcome from systemic therapy for primary operable breast cancer.
Academic Article Prediction of clinical outcome from primary tamoxifen by expression of biologic markers in breast cancer patients.
Academic Article ICI 182,780 (Faslodex): development of a novel, "pure" antiestrogen.
Academic Article Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy.
Academic Article Growth factor signalling and response to endocrine therapy: the Royal Marsden Experience.
Academic Article Targeting HER2 for the treatment of breast cancer.
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  • Estrogens