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CROWE, JAMES

One or more keywords matched the following items that are connected to CROWE, JAMES

Item Type	Name
Academic Article	Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats.
Academic Article	Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses.
Academic Article	Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia.
Academic Article	A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin.
Academic Article	A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin.
Academic Article	Differential regulation of granzyme and perforin in effector and memory T cells following smallpox immunization.
Academic Article	Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses.
Academic Article	Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Academic Article	Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence.
Academic Article	Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses.
Academic Article	Influenza virus resistance to human neutralizing antibodies.
Concept	Membrane Glycoproteins
Concept	Hemagglutinin Glycoproteins, Influenza Virus
Concept	Glycoproteins
Academic Article	Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site.
Academic Article	Committing the Oldest Sins in the Newest Kind of Ways-Antibodies Targeting the Influenza Virus Type A Hemagglutinin Globular Head.
Academic Article	Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites.
Academic Article	Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.
Academic Article	Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies.
Academic Article	Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence.
Academic Article	Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Academic Article	A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses.
Academic Article	Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Academic Article	The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Academic Article	Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region.
Academic Article	Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap.
Academic Article	A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Academic Article	Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors.
Academic Article	Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.
Academic Article	Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.
Academic Article	In?Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model.
Academic Article	Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine.
Academic Article	Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses.
Academic Article	Antibody Determinants of Influenza Immunity.
Academic Article	Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains.
Academic Article	HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Academic Article	Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein.
Grant	Alphavirus-based Vaccine for Prevention of MPV Infection
Grant	Epitope-Based Design and Modified RNA Platform for Bivalent Marburgvirus Vaccine
Concept	Spike Glycoprotein, Coronavirus
Academic Article	A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Academic Article	Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Academic Article	Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies.
Academic Article	Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants.
Academic Article	Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.
Academic Article	Potently neutralizing and protective human antibodies against SARS-CoV-2.
Academic Article	Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface.
Academic Article	Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring.
Academic Article	Angiotensin-converting Enzyme 2-containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein.
Academic Article	Discovery of Marburg virus neutralizing antibodies from virus-na?ve human antibody repertoires using large-scale structural predictions.
Academic Article	Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition.
Academic Article	Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Academic Article	Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies.
Academic Article	Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein.
Academic Article	Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions.
Academic Article	In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.
Academic Article	Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface.
Academic Article	Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell.
Academic Article	Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma.
Academic Article	Human antibody recognition of H7N9 influenza virus HA following natural infection.
Academic Article	A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
Academic Article	Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.
Academic Article	Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition.
Academic Article	Pan-ebolavirus protective therapy by two multifunctional human antibodies.
Academic Article	Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries.
Academic Article	A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques.
Academic Article	The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans.
Academic Article	Structural Biology Illuminates Molecular Determinants of Broad Ebolavirus Neutralization by Human Antibodies for Pan-Ebolavirus Therapeutic Development.
Academic Article	Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking.
Academic Article	An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies.
Academic Article	An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer.
Academic Article	Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Academic Article	Real-time cell analysis: A high-throughput approach for testing SARS-CoV-2 antibody neutralization and escape.
Academic Article	Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region.
Academic Article	Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains.
Academic Article	A bivalent SARS-CoV-2 monoclonal antibody combination does not affect the immunogenicity of a vector-based COVID-19 vaccine in macaques.
Academic Article	Systematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes.
Academic Article	Antiviral protection by antibodies targeting the glycan cap of Ebola virus glycoprotein requires activation of the complement system.
Academic Article	Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody.
Academic Article	Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination.
Academic Article	Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates.

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