| Item Type | Name |
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Concept
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Anticonvulsants
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Academic Article
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Teratogenicity of valproate conjugates with anticonvulsant activity in mice.
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Academic Article
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Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
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Academic Article
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Orofacial clefts and maternal anticonvulsant use.
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Academic Article
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Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
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Academic Article
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Effect of anti-epileptic drugs on intrauterine growth.
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Academic Article
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Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid.
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Academic Article
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Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus.
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Academic Article
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Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid.
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Academic Article
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Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
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Academic Article
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Valproic acid-induced skeletal malformations: associated gene expression cascades.
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Academic Article
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Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid.
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Academic Article
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Prenatal prediction of risk of the fetal hydantoin syndrome.
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Academic Article
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Mapping a chromosomal locus for valproic acid-induced exencephaly in mice.
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Academic Article
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Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
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Academic Article
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Clinical and experimental studies linking oxidative metabolism to phenytoin-induced teratogenesis.
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Academic Article
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Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
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Academic Article
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Protection from phenytoin-induced congenital malformations by coadministration of the antiepileptic drug stiripentol in a mouse model.
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Academic Article
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Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected].
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Academic Article
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Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
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Academic Article
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Effect of treatment with phenobarbital and stiripentol on carbamazepine-induced teratogenicity and reactive metabolite formation.
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Academic Article
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Protein-reactive metabolites of carbamazepine in mouse liver microsomes.
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Academic Article
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In utero antiepileptic drug exposure: fetal death and malformations.
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Academic Article
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Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide.
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Academic Article
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Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug.
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Academic Article
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Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice.
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Academic Article
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Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.
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Academic Article
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Phenytoin-induced alterations in craniofacial gene expression.
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Academic Article
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Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
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Academic Article
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Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 1: Animal studies.
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Academic Article
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Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 2: Human studies.
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Academic Article
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Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
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Academic Article
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Teratogenic effects of antiepileptic drugs.
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Academic Article
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Differences in the patterns of phenytoin-induced malformations following stiripentol coadministration in three inbred mouse strains.
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Academic Article
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Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model.
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Academic Article
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Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society.
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Academic Article
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Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society.
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Academic Article
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Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): obstetrical complications and change in seizure frequency: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society.
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Academic Article
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Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice.
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Academic Article
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Genetic differences in susceptibility to anticonvulsant drug-induced developmental defects.
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Academic Article
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Antiepileptic drugs and pregnancy outcomes.
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Academic Article
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Myo-inositol enhances teratogenicity of valproic acid in the mouse.
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Academic Article
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Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
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Academic Article
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Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid.
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Academic Article
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Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse.
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Academic Article
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Seizure control following administration of anticonvulsant drugs in the quaking mouse.
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Academic Article
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Pathobiology and genetics of neural tube defects.
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Academic Article
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Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide.
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Academic Article
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Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): I. Obstetrical complications and change in seizure frequency: Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the American Epilepsy Society.
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Academic Article
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Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurology and the American Epilepsy Society.
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Academic Article
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Management issues for women with epilepsy--focus on pregnancy (an evidence-based review): III. Vitamin K, folic acid, blood levels, and breast-feeding: Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the American Epilepsy Society.
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Academic Article
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Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.
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Academic Article
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Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
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Academic Article
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Neural tube defects, folate, and immune modulation.
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Academic Article
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Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice.
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Academic Article
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Metabolome-wide association study of anti-epileptic drug treatment during pregnancy.
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Grant
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ANTIEPILETIC DRUG SYNDROME--A MOLECULAR ANALYSIS
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Academic Article
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Fetal loss and malformations in the MONEAD study of pregnant women with epilepsy.
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Academic Article
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Approaches to studying the genomic architecture of complex birth defects.
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