Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus.

Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus. J Med Chem. 2013 Aug 22; 56(16):6467-77.

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subject areas

Acetamides
Amides
Animals
Anticonvulsants
Disease Models, Animal
Rats
Soman
Status Epilepticus
Stereoisomerism
Teratogens
Valproic Acid

authors with profiles

RICHARD FINNELL
BOGDAN WLODARCZYK