Header Logo

Search Result Details

Back to Search Results
This page shows the details of why an item matched the keywords from your search.
Search Results
DINARDO, COURTNEY
One or more keywords matched the following items that are connected to DINARDO, COURTNEY
Item TypeName
Concept Mutation
Concept Germ-Line Mutation
Concept Point Mutation
Concept Mutation, Missense
Academic Article MLL gene amplification in acute myeloid leukemia and myelodysplastic syndromes is associated with characteristic clinicopathological findings and TP53 gene mutation.
Academic Article Low frequency of H3.3 mutations and upregulated DAXX expression in MDS.
Academic Article Overexpression of the toll-like receptor (TLR) signaling adaptor MYD88, but lack of genetic mutation, in myelodysplastic syndromes.
Academic Article Atypical chronic myeloid leukemia is clinically distinct from unclassifiable myelodysplastic/myeloproliferative neoplasms.
Academic Article Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia.
Academic Article Lack of association of IDH1, IDH2 and DNMT3A mutations with outcome in older patients with acute myeloid leukemia treated with hypomethylating agents.
Academic Article Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML.
Academic Article Getting a handle on hereditary CEBPA mutations.
Academic Article Detectable FLT3-ITD or RAS mutation at the time of transformation from MDS to AML predicts for very poor outcomes.
Academic Article Evaluation of Patients and Families With Concern for Predispositions to Hematologic Malignancies Within the Hereditary Hematologic Malignancy Clinic (HHMC).
Academic Article IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progression
Academic Article Detectable FLT3-ITD or RAS mutation at the time of transformation from MDS to AML predicts for very poor outcomes
Academic Article Evidence for Clinical Differentiation and Differentiation Syndrome in Patients With Acute Myeloid Leukemia and IDH1 Mutations Treated With the Targeted Mutant IDH1 Inhibitor, AG-120
Academic Article TP53 mutations in newly diagnosed acute myeloid leukemia
Academic Article Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents
Academic Article Getting a handle on hereditary CEBPA mutations
Academic Article Isocitrate dehydrogenase mutations in myeloid malignancies
Academic Article Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents.
Academic Article TP53 mutations in newly diagnosed acute myeloid leukemia: Clinicomolecular characteristics, response to therapy, and outcomes.
Academic Article Targeting isocitrate dehydrogenase (IDH) in cancer.
Academic Article Evidence for Clinical Differentiation and Differentiation Syndrome in Patients With Acute Myeloid Leukemia and IDH1 Mutations Treated With the Targeted Mutant IDH1 Inhibitor, AG-120.
Academic Article Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
Academic Article Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study.
Academic Article Mutations in AML: prognostic and therapeutic implications.
Academic Article Bone marrow pathologic abnormalities in familial platelet disorder with propensity for myeloid malignancy and germline RUNX1 mutation.
Academic Article Vosaroxin in combination with decitabine in newly diagnosed older patients with acute myeloid leukemia or high-risk myelodysplastic syndrome.
Academic Article More than 1 TP53 abnormality is a dominant characteristic of pure erythroid leukemia.
Academic Article Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia.
Academic Article Novel Therapeutics in Acute Myeloid Leukemia.
Academic Article Clinical Outcomes and Co-Occurring Mutations in Patients with RUNX1-Mutated Acute Myeloid Leukemia.
Academic Article Targeting IDH1 and IDH2 Mutations in Acute Myeloid Leukemia.
Academic Article The role of IDH mutations in acute myeloid leukemia.
Academic Article Improving the detection of patients with inherited predispositions to hematologic malignancies using next-generation sequencing-based leukemia prognostication panels.
Academic Article Enasidenib for patients with relapsed acute myeloid leukemia and the IDH2 mutation.
Academic Article Outcomes with lower intensity therapy in TP53-mutated acute myeloid leukemia.
Academic Article Differentiation Syndrome Associated With Enasidenib, a Selective Inhibitor of Mutant Isocitrate Dehydrogenase 2: Analysis of a Phase 1/2 Study.
Academic Article Association of bone marrow fibrosis with inferior survival outcomes in chronic myelomonocytic leukemia.
Academic Article Characterization of IDH1 p.R132H Mutant Clones Using Mutation-specific Antibody in Myeloid Neoplasms.
Academic Article Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia.
Academic Article Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.
Academic Article Integrative genomic analysis of adult mixed phenotype acute leukemia delineates lineage associated molecular subtypes.
Academic Article Persistent IDH1/2 mutations in remission can predict relapse in patients with acute myeloid leukemia.
Academic Article Evolving Treatment Strategies for Elderly Leukemia Patients with IDH Mutations.
Academic Article Ivosidenib in IDH1-Mutated Acute Myeloid Leukemia.
Academic Article SOHO State of the Art Update and Next Questions: IDH Therapeutic Targeting in AML.
Academic Article Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.
Academic Article Validation of the 2017 European LeukemiaNet classification for acute myeloid leukemia with NPM1 and FLT3-internal tandem duplication genotypes.
Academic Article Advances in patient care through increasingly individualized therapy.
Academic Article Myeloid malignancies with somatic GATA2 mutations can be associated with an immunodeficiency phenotype.
Academic Article Hematologic malignancies and Li-Fraumeni syndrome.
Academic Article Phase II Trial of MEK Inhibitor Binimetinib (MEK162) in RAS-mutant Acute Myeloid Leukemia.
Academic Article Janus kinase 2 variants associated with the transformation of myeloproliferative neoplasms into acute myeloid leukemia.
Academic Article NPM1 mutations define a specific subgroup of MDS and MDS/MPN patients with favorable outcomes with intensive chemotherapy.
Academic Article Mutational landscape of myelodysplastic/myeloproliferative neoplasm-unclassifiable.
Academic Article DDX41 mutations in myeloid neoplasms are associated with male gender, TP53 mutations and high-risk disease.
Academic Article Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia.
Academic Article RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1.
Academic Article Severe therapy-related toxicities after treatment for Hodgkin lymphoma due to a pathogenic TERT variant and shortened telomeres.
Concept Mutation Rate
Academic Article Ibrutinib and Venetoclax for First-Line Treatment of CLL.
Academic Article Hereditary myeloid malignancies.
Academic Article Prognostic significance of baseline FLT3-ITD mutant allele level in acute myeloid leukemia treated with intensive chemotherapy with/without sorafenib.
Academic Article Sorafenib plus intensive chemotherapy improves survival in patients with newly diagnosed, FLT3-internal tandem duplication mutation-positive acute myeloid leukemia.
Academic Article Acute Myeloid Leukemia: from Mutation Profiling to Treatment Decisions.
Academic Article Successful lenalidomide treatment in high risk myelodysplastic syndrome with germline DDX41 mutation.
Academic Article ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants.
Academic Article How I treat acute myeloid leukemia in the era of new drugs.
Academic Article Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.
Academic Article Outcomes of acute myeloid leukemia with myelodysplasia related changes depend on diagnostic criteria and therapy.
Academic Article Venetoclax plus LDAC for newly diagnosed AML ineligible for intensive chemotherapy: a phase 3 randomized placebo-controlled trial.
Academic Article Clinico-pathologic characteristics and outcomes of the World Health Organization (WHO) provisional entity de novo acute myeloid leukemia with mutated RUNX1.
Academic Article Clinical pharmacokinetics and pharmacodynamics of ivosidenib in patients with advanced hematologic malignancies with an IDH1 mutation.
Academic Article Impact of numerical variation, allele burden, mutation length and co-occurring mutations on the efficacy of tyrosine kinase inhibitors in newly diagnosed FLT3- mutant acute myeloid leukemia.
Academic Article The Clinical impact of PTPN11 mutations in adults with acute myeloid leukemia.
Academic Article Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results.
Academic Article Clonal evolution and treatment outcomes in hematopoietic neoplasms arising in patients with germline RUNX1 mutations.
Academic Article Germline DNMT3A mutation in familial acute myeloid leukaemia.
Academic Article Hereditary Hematologic Malignancies.
Academic Article Germline Genetic Predisposition to Myeloid Neoplasia From GATA2 Gene Mutations: Lessons Learned From Two Cases.
Academic Article Gastrointestinal Hemorrhage: A Manifestation of the Telomere Biology Disorders.
Academic Article Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study.
Academic Article Outcomes with sequential FLT3-inhibitor-based therapies in patients with AML.
Academic Article Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.
Academic Article Clinical characteristics and outcomes in patients with acute myeloid leukemia with concurrent FLT3-ITD and IDH mutations.
Academic Article Clinical outcomes and influence of mutation clonal dominance in oligomonocytic and classical chronic myelomonocytic leukemia.
Academic Article Accurate germline RUNX1 variant interpretation and its clinical significance.
Academic Article Triplet therapy with venetoclax, FLT3 inhibitor and decitabine for FLT3-mutated acute myeloid leukemia.
Academic Article Decitabine and venetoclax for IDH1/2-mutated acute myeloid leukemia.
Academic Article Flow cytometric immunophenotypic alterations of persistent clonal haematopoiesis in remission bone marrows of patients with NPM1-mutated acute myeloid leukaemia.
Academic Article Acute myeloid leukemia: current progress and future directions.
Academic Article TAM kinases as regulators of cell death.
Academic Article Patterns of Resistance Differ in Patients with Acute Myeloid Leukemia Treated with Type I versus Type II FLT3 inhibitors.
Academic Article Acute myeloid leukemia: Treatment and research outlook for 2021 and the MD Anderson approach.
Academic Article Outcomes of patients with IDH1-mutant relapsed or refractory acute myeloid leukemia receiving ivosidenib who proceeded to hematopoietic stem cell transplant.
Academic Article EVI1 dysregulation: impact on biology and therapy of myeloid malignancies.
Academic Article Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia.
Academic Article Clinical, genomic, and transcriptomic differences between myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) and myelodysplastic syndrome with ring sideroblasts (MDS-RS).
Academic Article A phase I/II study of the combination of quizartinib with azacitidine or low-dose cytarabine for the treatment of patients with acute myeloid leukemia and myelodysplastic syndrome.
Academic Article Impact of splicing mutations in acute myeloid leukemia treated with hypomethylating agents combined with venetoclax.
Academic Article Clinicopathologic correlates and natural history of atypical chronic myeloid leukemia.
Academic Article Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia.
Academic Article A Case-Based Approach to Understanding Complex Genetic Information in an Evolving Landscape.
Academic Article Acute myeloid leukemia with IDH1 and IDH2 mutations: 2021 treatment algorithm.
Academic Article Post-transplantation donor-derived Sezary syndrome in a patient with A91V PRF1 variant hemophagocytic lymphohistiocytosis.
Academic Article Clonal dynamics and clinical implications of postremission clonal hematopoiesis in acute myeloid leukemia.
Academic Article Development of TP53 mutations over the course of therapy for acute myeloid leukemia.
Academic Article Association of unbalanced translocation der(1;7) with germline GATA2 mutations.
Academic Article Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements.
Academic Article Non-myeloablative umbilical cord blood transplantation for atypical dyskeratosis congenita.
Academic Article Effective therapy for AML with RUNX1 mutation by cotreatment with inhibitors of protein translation and BCL2.
Academic Article Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial.
Academic Article Acquired WT1 mutations contribute to relapse of NPM1-mutated acute myeloid leukemia following allogeneic hematopoietic stem cell transplant.
Academic Article Improved outcomes among newly diagnosed patients with FMS-like tyrosine kinase 3 internal tandem duplication mutated acute myeloid leukemia treated with contemporary therapy: Revisiting the European LeukemiaNet adverse risk classification.
Academic Article Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c).
Academic Article Impact of FLT3 Mutation on Outcomes after Venetoclax and Azacitidine for Patients with Treatment-Na?ve Acute Myeloid Leukemia.
Academic Article Combining Isocitrate Dehydrogenase Inhibitors With Existing Regimens in Acute Myeloid Leukemia: An Evolving Treatment Landscape.
Academic Article Efficacy and safety of enasidenib and azacitidine combination in patients with IDH2 mutated acute myeloid leukemia and not eligible for intensive chemotherapy.
Academic Article Impact of Venetoclax and Azacitidine in Treatment-Na?ve Patients with Acute Myeloid Leukemia and IDH1/2 Mutations.
Academic Article Prediction of survival with intensive chemotherapy in acute myeloid leukemia.
Academic Article Lenalidomide promotes the development of TP53-mutated therapy-related myeloid neoplasms.
Academic Article Resistance to targeted therapies: delving into FLT3 and IDH.
Academic Article Enasidenib vs conventional care in older patients with late-stage mutant-IDH2 relapsed/refractory AML: a randomized phase 3 trial.
Academic Article A dynamic 3-factor survival model for acute myeloid leukemia that accounts for response to induction chemotherapy.
Academic Article Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN.
Academic Article Targeted therapy with the mutant IDH2 inhibitor enasidenib for high-risk IDH2-mutant myelodysplastic syndrome.
Academic Article Implications of RAS mutational status in subsets of patients with newly diagnosed acute myeloid leukemia across therapy subtypes.
Academic Article Contemporary outcomes in IDH-mutated acute myeloid leukemia: The impact of co-occurring NPM1 mutations and venetoclax-based treatment.
Academic Article Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML.
Academic Article Approach Toward Germline Predisposition Syndromes in Patients with Hematologic Malignancies.
Academic Article Genomic profiling for clinical decision making in?myeloid neoplasms and acute leukemia.
Academic Article Common kinase mutations do not impact optimal molecular responses in core binding factor acute myeloid leukemia treated with fludarabine, cytarabine, and G-CSF based regimens.
Academic Article Outcomes in Patients With Poor-risk Cytogenetics With or Without TP53 Mutations Treated With Venetoclax and Azacitidine.
Academic Article Differential prognostic impact of RUNX1 mutations according to frontline therapy in patients with acute myeloid leukemia.
Academic Article Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1.
Academic Article Prediction of survival with lower intensity therapy among older patients with acute myeloid leukemia.
Academic Article Hypomorphic Brca2 and Rad51c double mutant mice display Fanconi anemia, cancer and polygenic replication stress.
Academic Article Causal linkage of presence of mutant NPM1 to efficacy of novel therapeutic agents against AML cells with mutant NPM1.
Academic Article Characteristics of patients with myelodysplastic neoplasm and spliceosome mutations.
Academic Article DDX41 mutations in patients with non-myeloid hematologic neoplasms.
Academic Article Germline Predisposition to Myelodysplastic Syndromes.
Academic Article Venetoclax abrogates the prognostic impact of splicing factor gene mutations in newly diagnosed acute myeloid leukemia.
Academic Article Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.
Academic Article IDH2 mutations in acute myeloid leukemia.
Academic Article Cigarette smoke exposure accelerates AML progression in FLT3-ITD models.
Academic Article Invasive mucorales sinusitis in a young patient with Emberger syndrome and newly diagnosed AML: A case report and literature review of invasive fungal infections in GATA2 deficiency.
Academic Article Phenotypic subtypes of leukaemic transformation in chronic myelomonocytic leukaemia.
Academic Article Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML.
Search Criteria
  • Mutation