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DEPINHO, RONALD A
One or more keywords matched the following items that are connected to DEPINHO, RONALD A
Item TypeName
Academic Article Impact papers on aging in 2009.
Academic Article Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Academic Article Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.
Academic Article Axis of ageing: telomeres, p53 and mitochondria.
Concept Telomere
Academic Article Essential role of mouse telomerase in highly proliferative organs.
Academic Article p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.
Academic Article A critical role for telomeres in suppressing and facilitating carcinogenesis.
Academic Article The age of cancer.
Academic Article Constitutive telomerase expression promotes mammary carcinomas in aging mice.
Academic Article Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing.
Academic Article Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells.
Academic Article The age of cancer: telomeres, checkpoints, and longevity.
Academic Article Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes.
Academic Article Telomere dysfunction induces metabolic and mitochondrial compromise.
Academic Article Telomere dysfunction alters the chemotherapeutic profile of transformed cells.
Academic Article Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression.
Academic Article Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation.
Academic Article Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma.
Academic Article mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells.
Academic Article Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Academic Article Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway.
Academic Article Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.
Academic Article Longevity, stress response, and cancer in aging telomerase-deficient mice.
Academic Article Telomere-dependent senescence.
Academic Article Mice without telomerase: what can they teach us about human cancer?
Academic Article Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation.
Academic Article Telomere dysfunction triggers developmentally regulated germ cell apoptosis.
Academic Article Connecting chromosomes, crisis, and cancer.
Academic Article Telomerase extracurricular activities.
Academic Article Telomeres, stem cells, senescence, and cancer.
Academic Article Cooperative interactions of p53 mutation, telomere dysfunction, and chronic liver damage in hepatocellular carcinoma progression.
Academic Article DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.
Academic Article Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse.
Academic Article Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.
Academic Article Telomeres and telomerase in cancer.
Academic Article Linking functional decline of telomeres, mitochondria and stem cells during ageing.
Academic Article Telomeres and mitochondria in the aging heart.
Academic Article Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.
Academic Article Unlimited mileage from telomerase?
Academic Article Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse.
Academic Article Cellular senescence: mitotic clock or culture shock?
Academic Article Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit.
Academic Article p53: good cop/bad cop.
Academic Article Telomeres and the DNA damage response: why the fox is guarding the henhouse.
Academic Article Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes.
Academic Article ZNF365 promotes stability of fragile sites and telomeres.
Academic Article Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery.
Academic Article Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.
Academic Article Diminished lifespan and acute stress-induced death in DNA-PKcs-deficient mice with limiting telomeres.
Academic Article Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy.
Academic Article Telomere dysfunction suppresses multiple endocrine neoplasia in mice.
Academic Article Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome.
Academic Article Quantification of telomere length by FISH and laser scanning cytometry
Academic Article Telomere dysfunction suppresses multiple endocrine Neoplasia in mice
Concept Telomere Homeostasis
Concept Telomere Shortening
Academic Article Programmable base editing of mutated TERT promoter inhibits brain tumour growth.
Academic Article Telomere dysfunction activates YAP1 to drive tissue inflammation.
Academic Article Telomeres: history, health, and hallmarks of aging.
Academic Article Telomere dysfunction instigates inflammation in inflammatory bowel disease.
Academic Article Telomere Dysfunction as an Initiator of Inflammation: Clues to an Age-Old Mystery.
Academic Article Telomere dysfunction alters intestinal stem cell dynamics to promote cancer.
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  • Telomere