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DEPINHO, RONALD A

One or more keywords matched the following items that are connected to DEPINHO, RONALD A

Item Type	Name
Academic Article	PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas.
Academic Article	Passenger deletions generate therapeutic vulnerabilities in cancer.
Concept	Glioblastoma
Academic Article	Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities.
Academic Article	Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies.
Academic Article	Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy.
Academic Article	Beyond effector caspase inhibition: Bcl2L12 neutralizes p53 signaling in glioblastoma.
Academic Article	Inhibitor of differentiation 4 drives brain tumor-initiating cell genesis through cyclin E and notch signaling.
Academic Article	What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator.
Academic Article	Emerging insights into the molecular and cellular basis of glioblastoma.
Academic Article	From the Cover: Neutralization of terminal differentiation in gliomagenesis.
Academic Article	Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway.
Academic Article	p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Academic Article	Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.
Academic Article	Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma.
Academic Article	STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA.
Academic Article	A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma.
Academic Article	Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma.
Academic Article	Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma.
Academic Article	Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.
Academic Article	QnAs with Ronald DePinho. Interview by Prashant Nair.
Academic Article	Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth.
Academic Article	Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth
Academic Article	PAF promotes stemness and radioresistance of glioma stem cells.
Academic Article	Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Academic Article	Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment.
Academic Article	Programmable base editing of mutated TERT promoter inhibits brain tumour growth.
Academic Article	Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.

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Glioblastoma