| Item Type | Name |
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Academic Article
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Selective lack of antibody to a component of EB nuclear antigen in patients with chronic active Epstein-Barr virus infection.
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Academic Article
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Antigenic and sequence variation in the C-terminal unique domain of the Epstein-Barr virus nuclear antigen EBNA-1.
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Academic Article
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Adenovirus-pulsed dendritic cells stimulate human virus-specific T-cell responses in vitro.
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Academic Article
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Gamma delta T lymphocyte regeneration after T lymphocyte-depleted bone marrow transplantation from mismatched family members or matched unrelated donors.
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Academic Article
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Induction of vigorous helper and cytotoxic T cell as well as B cell responses by dendritic cells expressing a modified antigen targeting receptor-mediated internalization pathway.
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Academic Article
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An Epstein-Barr virus deletion mutant associated with fatal lymphoproliferative disease unresponsive to therapy with virus-specific CTLs.
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Academic Article
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A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells.
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Academic Article
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Evidence for the presentation of major histocompatibility complex class I-restricted Epstein-Barr virus nuclear antigen 1 peptides to CD8+ T lymphocytes.
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Academic Article
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Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes.
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Academic Article
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Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy.
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Academic Article
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Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignancies.
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Academic Article
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Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells.
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Academic Article
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Improving T cell therapy for cancer.
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Academic Article
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Epstein Barr virus specific cytotoxic T lymphocytes expressing the anti-CD30zeta artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease.
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Academic Article
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Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia.
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Academic Article
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T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model.
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Academic Article
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Antigen-specific cytotoxic T lymphocytes can target chemoresistant side-population tumor cells in Hodgkin lymphoma.
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Academic Article
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Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety.
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Academic Article
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A comparison of gene transfer and antigen-loaded dendritic cells for the generation of CD4+ and CD8+ cytomegalovirus-specific T cells in HLA-A2+ and HLA-A2- donors.
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Academic Article
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Target antigen expression on a professional antigen-presenting cell induces superior proliferative antitumor T-cell responses via chimeric T-cell receptors.
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Academic Article
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Good manufacturing practice-grade cytotoxic T lymphocytes specific for latent membrane proteins (LMP)-1 and LMP2 for patients with Epstein-Barr virus-associated lymphoma.
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Academic Article
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Expansion of T cells targeting multiple antigens of cytomegalovirus, Epstein-Barr virus and adenovirus to provide broad antiviral specificity after stem cell transplantation.
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Academic Article
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HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy.
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Academic Article
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A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells.
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Academic Article
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Characterization of latent membrane protein 2 specificity in CTL lines from patients with EBV-positive nasopharyngeal carcinoma and lymphoma.
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Academic Article
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Evaluation of long-term transgene expression in piggyBac-modified human T lymphocytes.
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Academic Article
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Contact-activated monocytes: efficient antigen presenting cells for the stimulation of antigen-specific T cells.
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Academic Article
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Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy.
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Academic Article
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Immunotherapy for osteosarcoma: genetic modification of T cells overcomes low levels of tumor antigen expression.
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Academic Article
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Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes.
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Academic Article
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Accelerated production of antigen-specific T cells for preclinical and clinical applications using gas-permeable rapid expansion cultureware (G-Rex).
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Academic Article
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IRAK-M removal counteracts dendritic cell vaccine deficits in migration and longevity.
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Academic Article
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Generation of multivirus-specific T cells to prevent/treat viral infections after allogeneic hematopoietic stem cell transplant.
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Academic Article
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Combining mTor inhibitors with rapamycin-resistant T cells: a two-pronged approach to tumor elimination.
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Academic Article
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Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma.
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Academic Article
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A Th1-inducing adenoviral vaccine for boosting adoptively transferred T cells.
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Academic Article
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High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells.
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Academic Article
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Ex vivo gene transfer for improved adoptive immunotherapy of cancer.
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Academic Article
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CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients.
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Academic Article
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Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation.
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Academic Article
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PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor.
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Academic Article
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Epstein-Barr virus-positive Burkitt's lymphoma cells not recognized by virus-specific T-cell surveillance.
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Academic Article
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Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the treatment of patients with EBV-positive relapsed Hodgkin's disease.
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Academic Article
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Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: a potential treatment strategy for Epstein-Barr virus--positive Hodgkin's lymphoma.
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Academic Article
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Identification of a naturally processed HLA-DR-restricted T-helper epitope in Epstein-Barr virus nuclear antigen type 1.
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Academic Article
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Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes.
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Academic Article
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In vivo expansion of LMP 1- and 2-specific T-cells in a patient who received donor-derived EBV-specific T-cells after allogeneic stem cell transplantation.
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Academic Article
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Autologous designer antigen-presenting cells by gene modification of T lymphocyte blasts with IL-7 and IL-12.
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Academic Article
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Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer.
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Academic Article
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Gene-engineered varicella-zoster virus reactive CD4+ cytotoxic T cells exert tumor-specific effector function.
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Academic Article
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Using dendritic cell maturation and IL-12 producing capacity as markers of function: a cautionary tale.
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Academic Article
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Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation.
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Academic Article
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Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b.
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Academic Article
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Enhancement of dendritic cells as vaccines for cancer.
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Academic Article
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Production of good manufacturing practice-grade cytotoxic T lymphocytes specific for Epstein-Barr virus, cytomegalovirus and adenovirus to prevent or treat viral infections post-allogeneic hematopoietic stem cell transplant.
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Concept
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Antigen Presentation
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Concept
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Receptors, Antigen
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
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Concept
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Receptors, Antigen, T-Cell
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Concept
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T-Cell Antigen Receptor Specificity
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Concept
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Lymphocyte Function-Associated Antigen-1
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Concept
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Antigen-Antibody Reactions
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Concept
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Antigen-Presenting Cells
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Concept
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B7-1 Antigen
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Concept
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Ki-1 Antigen
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Concept
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B7-2 Antigen
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Concept
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HLA-A2 Antigen
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Concept
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Receptors, Antigen, T-Cell, gamma-delta
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Academic Article
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Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15.
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Academic Article
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Kinetics of tumor destruction by chimeric antigen receptor-modified T cells.
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Academic Article
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Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity.
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Academic Article
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Anti-leukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.
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Academic Article
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Toward immunotherapy with redirected T cells in a large animal model: ex vivo activation, expansion, and genetic modification of canine T cells.
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Academic Article
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Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma.
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Academic Article
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Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
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Academic Article
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Early transduction produces highly functional chimeric antigen receptor-modified virus-specific T-cells with central memory markers: a Production Assistant for Cell Therapy (PACT) translational application.
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Academic Article
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CMV-specific T cells generated from na?ve T cells recognize atypical epitopes and may be protective in vivo.
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Academic Article
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Peripheral blood-derived virus-specific memory stem T cells mature to functional effector memory subsets with self-renewal potency.
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Academic Article
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Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs.
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Academic Article
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Antigen-specific T cell therapies for cancer.
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Academic Article
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Clinical responses with T lymphocytes targeting malignancy-associated ? light chains.
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Academic Article
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Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer.
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Academic Article
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Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells.
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Academic Article
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HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial.
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Academic Article
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Comprehensive Approach for Identifying the T Cell Subset Origin of CD3 and CD28 Antibody-Activated Chimeric Antigen Receptor-Modified T Cells.
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Academic Article
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CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma.
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Academic Article
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Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes.
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Academic Article
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Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells.
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Academic Article
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Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1.
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Academic Article
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Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent.
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Academic Article
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Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells.
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Academic Article
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Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo.
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Academic Article
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Strategies for enhancing adoptive T-cell immunotherapy against solid tumors using engineered cytokine signaling and other modalities.
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Academic Article
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NK Cells Expressing a Chimeric Activating Receptor Eliminate MDSCs and Rescue Impaired CAR-T Cell Activity against Solid Tumors.
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Academic Article
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Chimeric Antigen Receptor Signaling Domains Differentially Regulate Proliferation and Native T Cell Receptor Function in Virus-Specific T Cells.
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Grant
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CYTOTOXIC T CELL TRANSFER FOR THERAPY OF EBV LYMPHOMA
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Grant
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ENHANCING T CELL THERAPY OF CANCER
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Academic Article
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In?Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas.
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Concept
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MART-1 Antigen
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Concept
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HLA-A11 Antigen
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Academic Article
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T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy.
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Academic Article
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A strategy to protect off-the-shelf cell therapy products using virus-specific T-cells engineered to eliminate alloreactive T-cells.
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Academic Article
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T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor-Expressing T Cells.
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Academic Article
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Oncolytic measles virus therapy enhances tumor antigen-specific T-cell responses in patients with multiple myeloma.
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Academic Article
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Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma.
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Academic Article
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CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity.
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Academic Article
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Donor-derived multiple leukemia antigen-specific T-cell therapy to prevent relapse after transplant?in patients with ALL.
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Academic Article
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A Costimulatory CAR Improves TCR-based Cancer Immunotherapy.
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Academic Article
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Multi-antigen-targeted T-cell therapy to treat patients with relapsed/refractory breast cancer.
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Academic Article
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Banking on virus-specific T cells to fulfill the need for?off-the-shelf cell therapies.
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Academic Article
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Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy.
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Academic Article
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Structural surfaceomics reveals an AML-specific conformation of integrin ?2 as a CAR T cellular therapy target.
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Academic Article
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Constitutive Interleukin-7 Cytokine Signaling Enhances the Persistence of Epstein-Barr Virus-Specific T-Cells.
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Academic Article
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Incongruity between T cell receptor recognition of breast cancer hotspot mutations ESR1 Y537S and D538G following exogenous peptide loading versus endogenous antigen processing.
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Academic Article
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Eighteen-year survival after GD2-directed Chimeric Antigen Receptor-Modified Immune Effector Cell Treatment for Neuroblastoma.
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