| Item Type | Name |
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Concept
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Teratogens
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Academic Article
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Lack of concordance between heat shock proteins and the development of tolerance to teratogen-induced neural tube defects.
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Academic Article
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Valproic acid-induced changes in gene expression during neurulation in a mouse model.
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Academic Article
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Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
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Academic Article
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Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity.
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Academic Article
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Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus.
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Academic Article
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Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid.
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Academic Article
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Investigations into the etiology of neural tube defects.
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Academic Article
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Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice.
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Academic Article
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Common hierarchies of susceptibility to the induction of neural tube defects in mouse embryos by valproic acid and its 4-propyl-4-pentenoic acid metabolite.
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Academic Article
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Strain-dependent alterations in the expression of folate pathway genes following teratogenic exposure to valproic acid in a mouse model.
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Academic Article
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Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
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Academic Article
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The heat shock response: potential to screen teratogens.
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Academic Article
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Molecular basis of environmentally induced birth defects.
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Academic Article
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Phenytoin-induced teratogenesis: a mouse model.
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Academic Article
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Brief report novel mechanism for valproate-induced teratogenicity.
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Academic Article
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Role of arsenic as a reproductive toxin with particular attention to neural tube defects.
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Academic Article
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Characterization of carbamazepine metabolism in a mouse model of carbamazepine teratogenicity.
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Academic Article
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Effects of folate supplementation on the risk of spontaneous and induced neural tube defects in Splotch mice.
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Academic Article
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Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity.
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Academic Article
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Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected].
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Academic Article
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Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice.
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Academic Article
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Teratology: general considerations and principles.
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Academic Article
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Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects.
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Academic Article
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Molecular basis for skeletal variation: insights from developmental genetic studies in mice.
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Academic Article
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Altered gene expression in murine branchial arches following in utero exposure to retinoic acid.
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Academic Article
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Strain differences in phenobarbital-induced teratogenesis in mice.
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Academic Article
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Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model.
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Academic Article
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Strain differences in heat-induced neural tube defects in mice.
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Academic Article
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Genetic background: the elusive component in the fetal hydantoin syndrome.
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Academic Article
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Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice.
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Academic Article
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Genetic differences in susceptibility to anticonvulsant drug-induced developmental defects.
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Academic Article
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Myo-inositol enhances teratogenicity of valproic acid in the mouse.
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Academic Article
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Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression.
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Academic Article
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Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse.
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Academic Article
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Failure of epoxide formation to influence carbamazepine-induced teratogenesis in a mouse model.
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Academic Article
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Investigation of the teratogenic effects of exercise on pregnancy outcome in mice.
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Academic Article
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Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide.
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Academic Article
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Genetic basis of susceptibility to teratogen induced birth defects.
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Academic Article
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Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.
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Academic Article
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Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
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Academic Article
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Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice.
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Academic Article
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Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure.
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Grant
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THE HEAT SHOCK RESPONSE: POTENTIAL TO SCREEN TERATOGENS
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