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CARTER, BING Z

One or more keywords matched the following items that are connected to CARTER, BING Z

Item Type	Name
Concept	X-Linked Inhibitor of Apoptosis Protein
Concept	Apoptosis
Concept	Inhibitor of Apoptosis Proteins
Concept	Apoptosis Regulatory Proteins
Concept	Receptors, TNF-Related Apoptosis-Inducing Ligand
Concept	TNF-Related Apoptosis-Inducing Ligand
Academic Article	Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
Academic Article	Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
Academic Article	MEK blockade converts AML differentiating response to retinoids into extensive apoptosis.
Academic Article	Triptolide induces cell death independent of cellular responses to imatinib in blast crisis chronic myelogenous leukemia cells including quiescent CD34+ primitive progenitor cells.
Academic Article	Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML.
Academic Article	XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
Academic Article	Preclinical antileukemic activity, toxicology, toxicokinetics and formulation development of triptolide derivative MRx102.
Academic Article	Targeting Survivin expression induces cell proliferation defect and subsequent cell death involving mitochondrial pathway in myeloid leukemic cells.
Academic Article	Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells.
Academic Article	Dasatinib induces autophagic cell death in human ovarian cancer.
Academic Article	Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML.
Academic Article	Survivin is highly expressed in CD34(+)38(-) leukemic stem/progenitor cells and predicts poor clinical outcomes in AML.
Academic Article	XIAP antisense therapy with AEG 35156 in acute myeloid leukemia.
Academic Article	XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells.
Academic Article	Synergistic targeting of AML stem/progenitor cells with IAP antagonist birinapant and demethylating agents.
Academic Article	Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia.
Academic Article	Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis.
Academic Article	Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells.
Academic Article	Tetra-O-methyl nordihydroguaiaretic acid inhibits growth and induces death of leukemia cells independent of Cdc2 and survivin.
Academic Article	Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5.
Academic Article	Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells.
Academic Article	Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance.
Academic Article	Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.
Academic Article	Apoptosis in leukemias: regulation and therapeutic targeting.
Academic Article	Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia.
Academic Article	Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer.
Academic Article	Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms.
Academic Article	Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34+ proliferating and quiescent chronic myeloid leukemia blast crisis cells.
Academic Article	Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms
Academic Article	Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NF?B/IL1? signaling network.
Academic Article	Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms.
Academic Article	Focal Adhesion Kinase as a Potential Target in AML and MDS.
Academic Article	Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells.
Academic Article	miR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathways.
Academic Article	Disruption of Wnt/?-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3-Mutant Acute Myeloid Leukemia.
Academic Article	An ARC-Regulated IL1?/Cox-2/PGE2/?-Catenin/ARC Circuit Controls Leukemia-Microenvironment Interactions and Confers Drug Resistance in AML.
Academic Article	SMAC mimetics as potential cancer therapeutics in myeloid malignancies.
Academic Article	Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 Enhances Antileukemia Activity of Venetoclax in Acute Myeloid Leukemia.
Academic Article	A novel HDAC inhibitor chidamide combined with imatinib synergistically targets tyrosine kinase inhibitor resistant chronic myeloid leukemia cells.
Academic Article	Combining triptolide with ABT-199 is effective against acute myeloid leukemia through reciprocal regulation of Bcl-2 family proteins and activation of the intrinsic apoptotic pathway.
Academic Article	Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and resensitizes acute myeloid leukemia to BCL-2 inhibition.
Academic Article	Inhibition of EZH2 by chidamide exerts antileukemia activity and increases chemosensitivity through Smo/Gli-1 pathway in acute myeloid leukemia.
Academic Article	Final results of a phase 2 clinical trial of LCL161, an oral SMAC mimetic for patients with myelofibrosis.
Academic Article	AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3-ITD acute myeloid leukemia.
Academic Article	Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic-Resistant AML and AML Stem Cells.
Academic Article	Beyond BCL-2 Inhibition in Acute Myloid Leukemia: Other Approaches to Leverage the Apoptotic Pathway.
Academic Article	Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
Academic Article	Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia.
Academic Article	Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells.
Academic Article	Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias.

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Apoptosis