DANNY EAPEN

TitleSenior Faculty
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address6620 MAIN
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bardach SH, Blike G, Sperling L, Kim K, Furman BW, Kulp DRG, Lam S, Eapen D, Orr JA, Hennessey KC, McGowan MP, Khera A, Gulati M, Ahmad Z, Triana T, Mittman BS, Wilemon K. Novel strategies to FIND people living with genetic dyslipidemias: The family heart foundation flag, identify, network, and deliver (FIND) familial hypercholesterolemia collaborative learning network. Am J Prev Cardiol. 2025 Sep; 23:101275. PMID: 40978297; PMCID: PMC12448033.
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    2. Osei J, Razavi AC, Quyyumi AA, Eapen DJ, Sun YV, Khoury MJ, Sperling L. Sex and racial differences in prevalence and clinical characteristics of people living with LDLR and PCSK9 familial hypercholesterolemia genetic variants: Data from the All of Us Research program. Am J Prev Cardiol. 2025 Jun; 22:101024. PMID: 40534628; PMCID: PMC12173703.
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    3. Razavi AC, Richardson LC, Coronado F, Vesper HW, Lyle A, Bhatia HS, Tsimikas S, Quyyumi AA, Vaccarino V, Eapen DJ, Isiadinso I, Mehta A, Yadalam AK, Osei J, Jacobson TA, Yao Z, Dzaye O, Martin SS, Nasir K, Shapiro MD, Blaha MJ, Whelton SP, Blumenthal RS, Sperling LS. Prevalence and Correlates of Lipoprotein(a) Testing in a Diverse Cohort of U.S. Adults. JACC Adv. 2025 May 30; 4(6 Pt 1):101826. PMID: 40570403; PMCID: PMC12164155.
      Citations: 2     
    4. Kim K, Faruque SC, Lam S, Kulp D, He X, Sperling LS, Eapen DJ. Implications of Diagnosis Through a Machine Learning Algorithm on Management of People With Familial?Hypercholesterolemia. JACC Adv. 2024 Sep; 3(9):101184. PMID: 39372480; PMCID: PMC11450951.
      Citations: 1     
    5. Kim K, Faruque SC, Kulp D, Lam S, Sperling LS, Eapen DJ. Primary care clinician engagement in implementing a machine-learning algorithm for targeted screening of familial hypercholesterolemia. Am J Prev Cardiol. 2024 Sep; 19:100710. PMID: 39176132; PMCID: PMC11338952.
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    6. Tso JV, Turner CG, Liu C, Miller AB, Eapen DJ, Sperling LS, Kim JH. Exercise blood pressure changes and aortic dilatation in male Masters endurance athletes. Eur J Prev Cardiol. 2023 03 27; 30(5):e18-e20. PMID: 36306424.
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    7. Patel P, Dhindsa D, Eapen DJ, Khera A, Gulati M, Stone NJ, Yancy CW, Rumsfeld JS, Sperling LS. Optimizing the Potential for Telehealth in Cardiovascular Care (in the Era of COVID-19): Time Will Tell. Am J Med. 2021 08; 134(8):945-951. PMID: 33845033; PMCID: PMC8553403.
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    8. Schultz WM, Varghese T, Heinl RE, Dhindsa DS, Mahlof EN, Cai HC, Southmayd G, Sandesara PB, Eapen DJ, Sperling LS. Natural Approaches in Diabetes Management: A Review of Diet, Exercise, and Natural Products. Curr Pharm Des. 2018; 24(1):84-98. PMID: 27981905.
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    9. Dhindsa DS, Khambhati J, Sandesara PB, Eapen DJ, Quyyumi AA. Biomarkers to Predict Cardiovascular Death. Card Electrophysiol Clin. 2017 12; 9(4):651-664. PMID: 29173408.
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    10. Schultz WM, Mahlof EN, Dhindsa DS, Varghese T, Heinl RE, Cai HC, Sandesara PB, Eapen DJ, Sperling LS. Cardiovascular disease risk reduction in diabetes through conventional and natural approaches. Cardiovasc Endocrinol. 2017 Dec; 6(4):128-135. PMID: 31646130; PMCID: PMC6768523.
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    11. Corrigan FE, Kelli HM, Dhindsa DS, Heinl RE, Al Mheid I, Hammadah M, Hayek SS, Sher S, Eapen DJ, Martin GS, Quyyumi AA. Changes in truncal obesity and fat distribution predict arterial health. J Clin Lipidol. 2017 Nov - Dec; 11(6):1354-1360.e3. PMID: 28942095; PMCID: PMC9136712.
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    12. Hammadah M, Kindya BR, Allard-Ratick MP, Jazbeh S, Eapen D, Wilson Tang WH, Sperling L. Navigating air travel and cardiovascular concerns: Is the sky the limit? Clin Cardiol. 2017 Sep; 40(9):660-666. PMID: 28597566; PMCID: PMC6490424.
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    13. Ghasemzedah N, Hayek SS, Ko YA, Eapen DJ, Patel RS, Manocha P, Al Kassem H, Khayata M, Veledar E, Kremastinos D, Thorball CW, Pielak T, Sikora S, Zafari AM, Lerakis S, Sperling L, Vaccarino V, Epstein SE, Quyyumi AA. Pathway-Specific Aggregate Biomarker Risk Score Is Associated With Burden of Coronary Artery Disease and Predicts Near-Term Risk of Myocardial Infarction and Death. Circ Cardiovasc Qual Outcomes. 2017 03; 10(3). PMID: 28280039; PMCID: PMC5874795.
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    14. Routledge FS, Dunbar SB, Higgins M, Rogers AE, Feeley C, Ioachimescu O, Euwer K, Eapen D, Quyyumi A. Insomnia Symptoms Are Associated With Abnormal Endothelial Function. J Cardiovasc Nurs. 2017 Jan/Feb; 32(1):78-85. PMID: 26488555; PMCID: PMC4837092.
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    15. Heinl RE, Dhindsa DS, Mahlof EN, Schultz WM, Ricketts JC, Varghese T, Esmaeeli A, Allard-Ratick MP, Millard AJ, Kelli HM, Sandesara PB, Eapen DJ, Sperling L. Comprehensive Cardiovascular Risk Reduction and Cardiac Rehabilitation in Diabetes and the Metabolic Syndrome. Can J Cardiol. 2016 10; 32(10 Suppl 2):S349-S357. PMID: 27692115; PMCID: PMC5320578.
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    16. Patel RS, Ghasemzadeh N, Eapen DJ, Sher S, Arshad S, Ko YA, Veledar E, Samady H, Zafari AM, Sperling L, Vaccarino V, Jones DP, Quyyumi AA. Response to Letter Regarding Article "Novel Biomarker of Oxidative Stress Is Associated With Risk of Death in Patients With Coronary Artery Disease". Circulation. 2016 May 31; 133(22):e667. PMID: 27245653; PMCID: PMC4981880.
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    17. Varghese T, Schultz WM, McCue AA, Lambert CT, Sandesara PB, Eapen DJ, Gordon NF, Franklin BA, Sperling LS. Physical activity in the prevention of coronary heart disease: implications for the clinician. Heart. 2016 06 15; 102(12):904-9. PMID: 26941396.
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    18. Corban MT, Hung OY, Mekonnen G, Eshtehardi P, Eapen DJ, Rasoul-Arzrumly E, Al Kassem H, Manocha P, Ko YA, Sperling LS, Quyyumi AA, Samady H. Elevated Levels of Serum Fibrin and Fibrinogen Degradation Products Are Independent Predictors of Larger Coronary Plaques and Greater Plaque Necrotic Core. Circ J. 2016; 80(4):931-7. PMID: 26911453; PMCID: PMC4857724.
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    19. Patel RS, Ghasemzadeh N, Eapen DJ, Sher S, Arshad S, Ko YA, Veledar E, Samady H, Zafari AM, Sperling L, Vaccarino V, Jones DP, Quyyumi AA. Novel Biomarker of Oxidative Stress Is Associated With Risk of Death in Patients With Coronary Artery Disease. Circulation. 2016 Jan 26; 133(4):361-9. PMID: 26673559; PMCID: PMC4722941.
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    20. MacNamara J, Eapen DJ, Quyyumi A, Sperling L. Novel biomarkers for cardiovascular risk assessment: current status and future directions. Future Cardiol. 2015 Sep; 11(5):597-613. PMID: 26491788.
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    21. Corrigan FE, Al Mheid I, Eapen DJ, Hayek SS, Sher S, Martin GS, Quyyumi AA. Low testosterone in men predicts impaired arterial elasticity and microvascular function. Int J Cardiol. 2015 Sep 01; 194:94-9. PMID: 26022684; PMCID: PMC9135451.
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    22. Mekonnen G, Corban MT, Hung OY, Eshtehardi P, Eapen DJ, Al-Kassem H, Rasoul-Arzrumly E, Gogas BD, McDaniel MC, Pielak T, Thorball CW, Sperling L, Quyyumi AA, Samady H. Plasma soluble urokinase-type plasminogen activator receptor level is independently associated with coronary microvascular function in patients with non-obstructive coronary artery disease. Atherosclerosis. 2015 Mar; 239(1):55-60. PMID: 25574858.
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    23. Lambert CT, Sandesara P, Isiadinso I, Gongora MC, Eapen D, Bhatia N, Baer JT, Sperling L. Current Treatment of Familial Hypercholesterolaemia. Eur Cardiol. 2014 Dec; 9(2):76-81. PMID: 30310490; PMCID: PMC6159444.
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    24. Ghasemzadeh N, Hritani AW, De Staercke C, Eapen DJ, Veledar E, Al Kassem H, Khayata M, Zafari AM, Sperling L, Hooper C, Vaccarino V, Mavromatis K, Quyyumi AA. Plasma stromal cell-derived factor 1a/CXCL12 level predicts long-term adverse cardiovascular outcomes in patients with coronary artery disease. Atherosclerosis. 2015 Jan; 238(1):113-8. PMID: 25461737; PMCID: PMC4721225.
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    25. Eapen DJ, Manocha P, Ghasemzadeh N, Patel RS, Al Kassem H, Hammadah M, Veledar E, Le NA, Pielak T, Thorball CW, Velegraki A, Kremastinos DT, Lerakis S, Sperling L, Quyyumi AA. Soluble urokinase plasminogen activator receptor level is an independent predictor of the presence and severity of coronary artery disease and of future adverse events. J Am Heart Assoc. 2014 10 23; 3(5):e001118. PMID: 25341887; PMCID: PMC4323820.
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    26. Wilmot KA, Khan A, Krishnan S, Eapen DJ, Sperling L. Statins in the elderly: a patient-focused approach. Clin Cardiol. 2015 Jan; 38(1):56-61. PMID: 25336290; PMCID: PMC6711018.
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    27. Patel RS, Li Q, Ghasemzadeh N, Eapen DJ, Moss LD, Janjua AU, Manocha P, Kassem HA, Veledar E, Samady H, Taylor WR, Zafari AM, Sperling L, Vaccarino V, Waller EK, Quyyumi AA. Circulating CD34+ progenitor cells and risk of mortality in a population with coronary artery disease. Circ Res. 2015 Jan 16; 116(2):289-297. PMID: 25323857; PMCID: PMC4715427.
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    28. Shah AJ, Ghasemzadeh N, Zaragoza-Macias E, Patel R, Eapen DJ, Neeland IJ, Pimple PM, Zafari AM, Quyyumi AA, Vaccarino V. Sex and age differences in the association of depression with obstructive coronary artery disease and adverse cardiovascular events. J Am Heart Assoc. 2014 Jun 18; 3(3):e000741. PMID: 24943475; PMCID: PMC4309058.
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    29. Kim J, Ghasemzadeh N, Eapen DJ, Chung NC, Storey JD, Quyyumi AA, Gibson G. Gene expression profiles associated with acute myocardial infarction and risk of cardiovascular death. Genome Med. 2014; 6(5):40. PMID: 24971157; PMCID: PMC4071233.
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    30. Ghasemzadeh N, Patel RS, Eapen DJ, Veledar E, Al Kassem H, Manocha P, Khayata M, Zafari AM, Sperling L, Jones DP, Quyyumi AA. Oxidative stress is associated with increased pulmonary artery systolic pressure in humans. Hypertension. 2014 Jun; 63(6):1270-5. PMID: 24614216; PMCID: PMC4138535.
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    31. Bellam N, Veledar E, Dorbala S, Di Carli MF, Shah S, Eapen D, Quyyumi A, Beanlands RS, Merhige ME, Williams BA, Chow BJ, Min JK, Berman DS, Shaw LJ. Prognostic significance of impaired chronotropic response to pharmacologic stress Rb-82 PET. J Nucl Cardiol. 2014 Apr; 21(2):233-44. PMID: 24482141.
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    32. Finn NA, Eapen D, Manocha P, Al Kassem H, Lassegue B, Ghasemzadeh N, Quyyumi A, Searles CD. Coronary heart disease alters intercellular communication by modifying microparticle-mediated microRNA transport. FEBS Lett. 2013 Nov 01; 587(21):3456-63. PMID: 24042051; PMCID: PMC3910498.
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    33. Eapen DJ, Manocha P, Patel RS, Hammadah M, Veledar E, Wassel C, Nanjundappa RA, Sikora S, Malayter D, Wilson PW, Sperling L, Quyyumi AA, Epstein SE. Aggregate risk score based on markers of inflammation, cell stress, and coagulation is an independent predictor of adverse cardiovascular outcomes. J Am Coll Cardiol. 2013 Jul 23; 62(4):329-37. PMID: 23665099; PMCID: PMC4066955.
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    34. Bhatia NK, Eapen DJ, Stewart JP, Babaliaros V, Sperling LS. Right coronary artery aneurysm communication with the right atrium following non-st-elevation myocardial infarction treated with coil embolization. Circulation. 2013 Apr 09; 127(14):e537-8. PMID: 23569122.
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    35. Helgadottir A, Gretarsdottir S, Thorleifsson G, Holm H, Patel RS, Gudnason T, Jones GT, van Rij AM, Eapen DJ, Baas AF, Tregouet DA, Morange PE, Emmerich J, Lindblad B, Gotts?ter A, Kiemeny LA, Lindholt JS, Sakalihasan N, Ferrell RE, Carey DJ, Elmore JR, Tsao PS, Grarup N, J?rgensen T, Witte DR, Hansen T, Pedersen O, Pola R, Gaetani E, Magnadottir HB, Wijmenga C, Tromp G, Ronkainen A, Ruigrok YM, Blankensteijn JD, Mueller T, Wells PS, Corral J, Soria JM, Souto JC, Peden JF, Jalilzadeh S, Mayosi BM, Keavney B, Strawbridge RJ, Sabater-Lleal M, Gertow K, Baldassarre D, Nyyss?nen K, Rauramaa R, Smit AJ, Mannarino E, Giral P, Tremoli E, de Faire U, Humphries SE, Hamsten A, Haraldsdottir V, Olafsson I, Magnusson MK, Samani NJ, Levey AI, Markus HS, Kostulas K, Dichgans M, Berger K, Kuhlenb?umer G, Ringelstein EB, Stoll M, Seedorf U, Rothwell PM, Powell JT, Kuivaniemi H, Onundarson PT, Valdimarsson E, Matthiasson SE, Gudbjartsson DF, Thorgeirsson G, Quyyumi AA, Watkins H, Farrall M, Thorsteinsdottir U, Stefansson K. Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. J Am Coll Cardiol. 2012 Aug 21; 60(8):722-9. PMID: 22898070.
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    36. Ramjee V, Eapen DJ, Sperling LS. Optimal lipid targets for the new era of cardiovascular prevention. Ann N Y Acad Sci. 2012 Apr; 1254:106-114. PMID: 22548576.
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    37. Eapen DJ, Clements S, Block P, Sperling L. Metastatic carcinoid disease inducing coronary vasospasm. Tex Heart Inst J. 2012; 39(1):76-8. PMID: 22412234; PMCID: PMC3298897.
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    38. Morgan TM, House JA, Cresci S, Jones P, Allayee H, Hazen SL, Patel Y, Patel RS, Eapen DJ, Waddy SP, Quyyumi AA, Kleber ME, M?rz W, Winkelmann BR, Boehm BO, Krumholz HM, Spertus JA. Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome. BMC Med Genet. 2011 Sep 29; 12:127. PMID: 21957892; PMCID: PMC3190329.
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    39. Eapen DJ, Valiani K, Reddy S, Sperling L. Management of familial hypercholesterolemia during pregnancy: case series and discussion. J Clin Lipidol. 2012 Jan-Feb; 6(1):88-91. PMID: 22264579.
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    40. Eapen DJ, Manocha P, Valiani K, Mantini N, Sperling L, McGorisk GM. Alcohol and the heart: an ounce of prevention. Curr Treat Options Cardiovasc Med. 2011 Aug; 13(4):313-25. PMID: 21562797.
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    41. Patel RS, Eapen DJ, Zafari AM, Vaccarino V, Quyyumi AA. Letter by patel et Al regarding article "Chromosome 9p21 haplotypes and prognosis in white and black patients with coronary artery disease". Circ Cardiovasc Genet. 2011 Aug 01; 4(4):e11; author reply e12. PMID: 21846864.
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    42. Abd TT, Eapen DJ, Bajpai A, Goyal A, Dollar A, Sperling L. The role of C-reactive protein as a risk predictor of coronary atherosclerosis: implications from the JUPITER trial. Curr Atheroscler Rep. 2011 Apr; 13(2):154-61. PMID: 21274757.
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    43. Post A, Kurc T, Overcash M, Cantrell D, Morris T, Eckerson K, Tsui C, Willey T, Quyyumi A, Eapen D, Umpierrez G, Ziemer D, Saltz J. A Temporal Abstraction-based Extract, Transform and Load Process for Creating Registry Databases for Research. AMIA Jt Summits Transl Sci Proc. 2011; 2011:46-50. PMID: 22211179; PMCID: PMC3248751.
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    44. Eapen DJ, Kalra GL, Rifai L, Eapen CA, Merchant N, Khan BV. Raising HDL cholesterol in women. Int J Womens Health. 2010 Aug 09; 1:181-91. PMID: 21072287; PMCID: PMC2971704.
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    45. Eapen D, Kalra GL, Merchant N, Arora A, Khan BV. Metabolic syndrome and cardiovascular disease in South Asians. Vasc Health Risk Manag. 2009; 5:731-43. PMID: 19756165; PMCID: PMC2742703.
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