Angiopoietin-like Proteins
"Angiopoietin-like Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that is structurally similar to ANGIOPOIETINS but do not bind angiopoietin receptors. They are characterized by an amino-terminal coiled-coil domain, a linker region, and a carboxy-terminal FIBRINOGEN-like domain with the exception of ANGPTL8, which lacks the fibrinogen-like domain. They function in a variety of developmental and physiological processes, including INFLAMMATION, lipid metabolism, hematopoietic stem cell activity, and cancer metastasis.
| Descriptor ID |
D000075802
|
| MeSH Number(s) |
D12.644.276.100.050 D12.776.467.100.050 D23.529.100.050
|
| Concept/Terms |
Angiopoietin-like Proteins- Angiopoietin-like Proteins
- Angiopoietin like Proteins
- Angiopoietin-like Protein
- Angiopoietin like Protein
- Angiopoietin-related Protein
- Angiopoietin related Protein
|
Below are MeSH descriptors whose meaning is more general than "Angiopoietin-like Proteins".
Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-like Proteins".
This graph shows the total number of publications written about "Angiopoietin-like Proteins" by people in this website by year, and whether "Angiopoietin-like Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 3 | 3 |
| 2022 | 0 | 2 | 2 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Angiopoietin-like Proteins" by people in Profiles.
-
Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with homozygous familial hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trial. Lancet Diabetes Endocrinol. 2026 Feb; 14(2):123-136.
-
Effect of physical activity in a weight loss program on circulating total ANGPTL8 concentrations in northern Americans with obesity: A prospective randomized controlled trial. Nutr Metab Cardiovasc Dis. 2022 07; 32(7):1725-1733.
-
Triglyceride-rich lipoproteins, apolipoprotein C-III, angiopoietin-like protein 3, and cardiovascular events in older adults: Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2022 03 11; 29(2):e53-e64.
-
Letter to the Editor: Increased Circulating Angiopoietin-like Protein 8 Levels Are Associated with Thoracic Aortic Dissection and Higher Inflammatory Conditions. Cardiovasc Drugs Ther. 2020 08; 34(4):589.
-
Fetal macrosomia in a Hispanic/Latinx predominant cohort and altered expressions of genes related to placental lipid transport and metabolism. Int J Obes (Lond). 2020 08; 44(8):1743-1752.
-
Triglycerides and ASCVD Risk Reduction: Recent Insights and Future Directions. Curr Atheroscler Rep. 2020 06 03; 22(7):25.
-
ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. J Am Coll Cardiol. 2017 Apr 25; 69(16):2054-2063.
-
Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19751-6.
-
Interaction between SNPs in the RXRA and near ANGPTL3 gene region inhibits apoB reduction after statin-fenofibric acid therapy in individuals with mixed dyslipidemia. J Lipid Res. 2012 Nov; 53(11):2425-8.
-
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. J Clin Invest. 2009 Jan; 119(1):70-9.