Angiopoietin-like Proteins
"Angiopoietin-like Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that is structurally similar to ANGIOPOIETINS but do not bind angiopoietin receptors. They are characterized by an amino-terminal coiled-coil domain, a linker region, and a carboxy-terminal FIBRINOGEN-like domain with the exception of ANGPTL8, which lacks the fibrinogen-like domain. They function in a variety of developmental and physiological processes, including INFLAMMATION, lipid metabolism, hematopoietic stem cell activity, and cancer metastasis.
Descriptor ID |
D000075802
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MeSH Number(s) |
D12.644.276.100.050 D12.776.467.100.050 D23.529.100.050
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Concept/Terms |
Angiopoietin-like Proteins- Angiopoietin-like Proteins
- Angiopoietin like Proteins
- Angiopoietin-like Protein
- Angiopoietin like Protein
- Angiopoietin-related Protein
- Angiopoietin related Protein
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Below are MeSH descriptors whose meaning is more general than "Angiopoietin-like Proteins".
Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-like Proteins".
This graph shows the total number of publications written about "Angiopoietin-like Proteins" by people in this website by year, and whether "Angiopoietin-like Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2012 | 0 | 2 | 2 |
2015 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2020 | 0 | 3 | 3 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Angiopoietin-like Proteins" by people in Profiles.
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Triglyceride-rich lipoproteins, apolipoprotein C-III, angiopoietin-like protein 3, and cardiovascular events in older adults: Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2022 03 11; 29(2):e53-e64.
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ANGPTL2-containing small extracellular vesicles from vascular endothelial cells accelerate leukemia progression. J Clin Invest. 2021 01 04; 131(1).
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Letter to the Editor: Increased Circulating Angiopoietin-like Protein 8 Levels Are Associated with Thoracic Aortic Dissection and Higher Inflammatory Conditions. Cardiovasc Drugs Ther. 2020 08; 34(4):589.
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Fetal macrosomia in a Hispanic/Latinx predominant cohort and altered expressions of genes related to placental lipid transport and metabolism. Int J Obes (Lond). 2020 08; 44(8):1743-1752.
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Triglycerides and ASCVD Risk Reduction: Recent Insights and Future Directions. Curr Atheroscler Rep. 2020 06 03; 22(7):25.
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ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. J Am Coll Cardiol. 2017 Apr 25; 69(16):2054-2063.
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Resolving Discrepant Findings on ANGPTL8 in ?-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy. PLoS One. 2016; 11(7):e0159276.
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An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis. Oncotarget. 2015 May 30; 6(15):13822-34.
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Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice. Diabetologia. 2015 Jul; 58(7):1523-31.
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Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19751-6.