rab27 GTP-Binding Proteins
"rab27 GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
GTP-binding proteins associated with membranes, MELANOSOMES; LYSOSOMES; and late ENDOSOMES. They play a role in the release of cytotoxic SECRETORY GRANULES from lymphocytes and are required for granule maturation, as well as granule docking and priming at IMMUNOLOGICAL SYNAPSES.
| Descriptor ID |
D000075745
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| MeSH Number(s) |
D08.811.277.040.330.300.400.400.075 D12.644.360.525.400.075 D12.776.157.325.515.400.075 D12.776.476.525.400.075
|
| Concept/Terms |
rab27 GTP-Binding Proteins- rab27 GTP-Binding Proteins
- GTP-Binding Proteins, rab27
- rab27 GTP Binding Proteins
- GTP-binding Protein Ram
- GTP binding Protein Ram
- Ram, GTP-binding Protein
- Rab27a Protein
- Rab27 Protein
|
Below are MeSH descriptors whose meaning is more general than "rab27 GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "rab27 GTP-Binding Proteins".
This graph shows the total number of publications written about "rab27 GTP-Binding Proteins" by people in this website by year, and whether "rab27 GTP-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "rab27 GTP-Binding Proteins" by people in Profiles.
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NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression. Cell Rep. 2021 10 19; 37(3):109856.
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Advances in clinical immunology in 2015. J Allergy Clin Immunol. 2016 12; 138(6):1531-1540.
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Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis. J Clin Invest. 2016 12 01; 126(12):4537-4553.
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A novel Rab27a mutation binds melanophilin, but not Munc13-4, causing immunodeficiency without albinism. J Allergy Clin Immunol. 2016 08; 138(2):599-601.e3.
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Distinct role of rab27a in granule movement at the plasma membrane and in the cytosol of NK cells. PLoS One. 2010 Sep 21; 5(9):e12870.
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Identification of an organelle receptor for myosin-Va. Nat Cell Biol. 2002 Apr; 4(4):271-8.
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Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle. J Cell Sci. 2001 Mar; 114(Pt 6):1091-100.
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A mutation in Rab27a causes the vesicle transport defects observed in ashen mice. Proc Natl Acad Sci U S A. 2000 Jul 05; 97(14):7933-8.