S100 Calcium-Binding Protein A4
"S100 Calcium-Binding Protein A4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS.
| Descriptor ID |
D000071999
|
| MeSH Number(s) |
D12.776.157.125.750.813
|
| Concept/Terms |
S100 Calcium-Binding Protein A4- S100 Calcium-Binding Protein A4
- S100 Calcium Binding Protein A4
- Metastasin Protein
- Placental Calcium-Binding Protein
- Calcium-Binding Protein, Placental
- Placental Calcium Binding Protein
- Calvasculin Protein
- Fibroblast-Specific Protein 1
- Fibroblast Specific Protein 1
- S100A4 Protein
|
Below are MeSH descriptors whose meaning is more general than "S100 Calcium-Binding Protein A4".
Below are MeSH descriptors whose meaning is more specific than "S100 Calcium-Binding Protein A4".
This graph shows the total number of publications written about "S100 Calcium-Binding Protein A4" by people in this website by year, and whether "S100 Calcium-Binding Protein A4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "S100 Calcium-Binding Protein A4" by people in Profiles.
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Notch Blockade Specifically in Bone Marrow-Derived FSP-1-Positive Cells Ameliorates Renal Fibrosis. Cells. 2023 01 04; 12(2).
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Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target. Nat Commun. 2022 02 09; 13(1):767.
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Mitochondrial regulation of ferroptosis. J Cell Biol. 2021 09 06; 220(9).
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Anti-S100A4 Antibody Therapy Is Efficient in Treating Aggressive Prostate Cancer and Reversing Immunosuppression: Serum and Biopsy S100A4 as a Clinical Predictor. Mol Cancer Ther. 2020 12; 19(12):2598-2611.
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S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation. JCI Insight. 2019 07 02; 5.
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Overexpression of S100A4 Predicts Migration, Invasion, and Poor Prognosis of Hypopharyngeal Squamous Cell Carcinoma. Mol Diagn Ther. 2019 06; 23(3):407-417.
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The Ser/Thr kinase p90RSK promotes kidney fibrosis by modulating fibroblast-epithelial crosstalk. J Biol Chem. 2019 06 21; 294(25):9901-9910.
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Notch signaling in bone marrow-derived FSP-1?cells initiates neointima formation in arteriovenous?fistulas. Kidney Int. 2019 06; 95(6):1347-1358.
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Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. EMBO Mol Med. 2018 10; 10(10).
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Integrin ?3 Mediates the Endothelial-to-Mesenchymal Transition via the Notch Pathway. Cell Physiol Biochem. 2018; 49(3):985.