Minimal Clinically Important Difference
"Minimal Clinically Important Difference" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A statistically significant minimum set of clinical outcomes that demonstrates a clinical benefit of an intervention or treatment.
| Descriptor ID |
D000071081
|
| MeSH Number(s) |
N04.761.559.590.399.750 N05.715.360.575.575.399.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Minimal Clinically Important Difference".
Below are MeSH descriptors whose meaning is more specific than "Minimal Clinically Important Difference".
This graph shows the total number of publications written about "Minimal Clinically Important Difference" by people in this website by year, and whether "Minimal Clinically Important Difference" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2019 | 3 | 1 | 4 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Minimal Clinically Important Difference" by people in Profiles.
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Minimum clinically important difference in Quantitative Lung Fibrosis score associated with all-cause mortality in idiopathic pulmonary fibrosis: subanalysis from two phase II trials of pamrevlumab. BMJ Open. 2025 May 12; 15(5):e094559.
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Ascertainment of Minimal Clinically Important Differences in the Diabetes Distress Scale-17: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2023 11 01; 6(11):e2342950.
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Quality of Life Effect of the Anti-CCR4 Monoclonal Antibody Mogamulizumab Versus Vorinostat in Patients With Cutaneous T-cell Lymphoma. Clin Lymphoma Myeloma Leuk. 2021 02; 21(2):97-105.
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Unique Substantial Clinical Benefit Values for the 12-Item International Hip Outcome Tool Based on Preoperative Level of Function. Arthroscopy. 2020 04; 36(4):1033-1038.
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A Comparison of Treatment Effects for Nonsurgical Therapies and the Minimum Clinically Important Difference in Knee Osteoarthritis: A Systematic Review. JBJS Rev. 2019 08; 7(8):e5.
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Minimal clinically important change in patients with cervical dystonia: Results from the CD PROBE study. J Neurol Sci. 2019 Oct 15; 405:116413.
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Early Experience and Results Using Patient-Reported Outcomes Measurement Information System Scores in Primary Total Hip and Knee Arthroplasty. J Arthroplasty. 2019 Oct; 34(10):2313-2318.
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Minimal Clinically Important Difference for PROMIS Physical Function in Patients With Distal Radius Fractures. J Hand Surg Am. 2019 Jun; 44(6):454-459.e1.
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The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium. Cancer. 2018 05 15; 124(10):2246-2252.
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Reliability and minimal clinically important differences of forced vital capacity: Results from the Scleroderma Lung Studies (SLS-I and SLS-II). Am J Respir Crit Care Med. 2018 03 01; 197(5):644-652.