THOMAS COOPER to Alternative Splicing
This is a "connection" page, showing publications THOMAS COOPER has written about Alternative Splicing.
Connection Strength
13.679
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Rescue of Scn5a mis-splicing does not improve the structural and functional heart defects of a DM1 heart mouse model. Hum Mol Genet. 2024 10 07; 33(20):1789-1799.
Score: 0.797
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The role of Limch1 alternative splicing in skeletal muscle function. Life Sci Alliance. 2023 06; 6(6).
Score: 0.717
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Alternative splicing mediates the compensatory upregulation of MBNL2 upon MBNL1 loss-of-function. Nucleic Acids Res. 2023 02 22; 51(3):1245-1259.
Score: 0.712
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Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions. Elife. 2017 08 11; 6.
Score: 0.485
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Alternative Splicing of Four Trafficking Genes Regulates Myofiber Structure and Skeletal Muscle Physiology. Cell Rep. 2016 11 15; 17(8):1923-1933.
Score: 0.461
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Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis. Mol Cell. 2014 Aug 21; 55(4):592-603.
Score: 0.393
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Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development. Nat Commun. 2014 Apr 22; 5:3603.
Score: 0.386
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Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron. Nucleic Acids Res. 2014 Feb; 42(3):1893-903.
Score: 0.373
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Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13570-5.
Score: 0.367
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Functional consequences of developmentally regulated alternative splicing. Nat Rev Genet. 2011 Sep 16; 12(10):715-29.
Score: 0.322
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Alternative splicing dysregulation secondary to skeletal muscle regeneration. Ann Neurol. 2011 Apr; 69(4):681-90.
Score: 0.311
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Identification of MBNL1 and MBNL3 domains required for splicing activation and repression. Nucleic Acids Res. 2011 Apr; 39(7):2769-80.
Score: 0.305
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Global regulation of alternative splicing during myogenic differentiation. Nucleic Acids Res. 2010 Nov; 38(21):7651-64.
Score: 0.297
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MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development. Genes Dev. 2010 Apr 01; 24(7):653-8.
Score: 0.291
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Chemical reversal of the RNA gain of function in myotonic dystrophy. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18433-4.
Score: 0.283
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A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20333-8.
Score: 0.266
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Splicing in disease: disruption of the splicing code and the decoding machinery. Nat Rev Genet. 2007 Oct; 8(10):749-61.
Score: 0.243
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Micromanaging alternative splicing during muscle differentiation. Dev Cell. 2007 Feb; 12(2):171-2.
Score: 0.234
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Alternative splicing in disease. Adv Exp Med Biol. 2007; 623:212-23.
Score: 0.233
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A bichromatic fluorescent reporter for cell-based screens of alternative splicing. Nucleic Acids Res. 2006; 34(22):e148.
Score: 0.231
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Minigene reporter for identification and analysis of cis elements and trans factors affecting pre-mRNA splicing. Biotechniques. 2006 Aug; 41(2):177-81.
Score: 0.226
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Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy. Prog Mol Subcell Biol. 2006; 44:133-59.
Score: 0.217
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Use of minigene systems to dissect alternative splicing elements. Methods. 2005 Dec; 37(4):331-40.
Score: 0.216
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Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development. Dev Dyn. 2005 Jul; 233(3):783-93.
Score: 0.210
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Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. Mol Cell Biol. 2005 Jul; 25(14):6267-78.
Score: 0.210
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Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy. J Cell Sci. 2005 Jul 01; 118(Pt 13):2923-33.
Score: 0.209
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Identification of CELF splicing activation and repression domains in vivo. Nucleic Acids Res. 2005; 33(9):2769-80.
Score: 0.208
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MBNL overexpression rescues cardiac phenotypes in a myotonic dystrophy type 1 heart mouse model. J Clin Invest. 2025 Feb 11; 135(7).
Score: 0.204
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Alternative splicing regulation impacts heart development. Cell. 2005 Jan 14; 120(1):1-2.
Score: 0.203
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Muscleblind proteins regulate alternative splicing. EMBO J. 2004 Aug 04; 23(15):3103-12.
Score: 0.196
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CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing. J Biol Chem. 2004 Apr 23; 279(17):17756-64.
Score: 0.190
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Clinical and Molecular Insights into Gastrointestinal Dysfunction in Myotonic Dystrophy Types 1 & 2. Int J Mol Sci. 2022 Nov 26; 23(23).
Score: 0.175
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Finding signals that regulate alternative splicing in the post-genomic era. Genome Biol. 2002 Oct 23; 3(11):reviews0008.
Score: 0.174
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Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing. Mol Cell. 2002 Jul; 10(1):45-53.
Score: 0.170
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Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Mol Cell. 2002 Mar; 9(3):649-58.
Score: 0.166
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Highlights of alternative splicing regulation session: yes, no, maybe--a history of paradigm shifts. Sci STKE. 2001 Oct 23; 2001(105):pe35.
Score: 0.162
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Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy. Nat Genet. 2001 Sep; 29(1):40-7.
Score: 0.161
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The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. EMBO J. 2001 Jul 16; 20(14):3821-30.
Score: 0.159
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The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing. Mol Cell Biol. 2001 Feb; 21(4):1285-96.
Score: 0.154
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Binding of PurH to a muscle-specific splicing enhancer functionally correlates with exon inclusion in vivo. J Biol Chem. 2000 Jul 07; 275(27):20618-26.
Score: 0.148
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Increased nuclear but not cytoplasmic activities of CELF1 protein leads to muscle wasting. Hum Mol Genet. 2020 06 27; 29(10):1729-1744.
Score: 0.148
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Endurance exercise leads to beneficial molecular and physiological effects in a mouse model of myotonic dystrophy type 1. Muscle Nerve. 2019 12; 60(6):779-789.
Score: 0.141
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Modulation of alternative splicing of trafficking genes by genome editing reveals functional consequences in muscle biology. Int J Biochem Cell Biol. 2018 12; 105:134-143.
Score: 0.132
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Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy. Science. 1998 May 01; 280(5364):737-41.
Score: 0.128
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The regulation of splice-site selection, and its role in human disease. Am J Hum Genet. 1997 Aug; 61(2):259-66.
Score: 0.121
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Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1. Sci Rep. 2016 10 19; 6:35550.
Score: 0.115
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Muscle-specific splicing enhancers regulate inclusion of the cardiac troponin T alternative exon in embryonic skeletal muscle. Mol Cell Biol. 1996 Aug; 16(8):4014-23.
Score: 0.113
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A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. Mol Cell Biol. 1995 Sep; 15(9):4898-907.
Score: 0.106
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RNA-binding proteins in heart development. Adv Exp Med Biol. 2014; 825:389-429.
Score: 0.094
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The cardiac troponin T alternative exon contains a novel purine-rich positive splicing element. Mol Cell Biol. 1993 Jun; 13(6):3660-74.
Score: 0.091
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CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1. Hum Mol Genet. 2010 Sep 15; 19(18):3614-22.
Score: 0.074
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Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1. Hum Mol Genet. 2010 Mar 15; 19(6):1066-75.
Score: 0.072
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The pathobiology of splicing. J Pathol. 2010 Jan; 220(2):152-63.
Score: 0.072
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Pathogenic mechanisms of myotonic dystrophy. Biochem Soc Trans. 2009 Dec; 37(Pt 6):1281-6.
Score: 0.071
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PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1. J Clin Invest. 2009 Dec; 119(12):3797-806.
Score: 0.071
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Molecular biology. Neutralizing toxic RNA. Science. 2009 Jul 17; 325(5938):272-3.
Score: 0.069
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RNA and disease. Cell. 2009 Feb 20; 136(4):777-93.
Score: 0.067
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Overexpression of MBNL1 fetal isoforms and modified splicing of Tau in the DM1 brain: two individual consequences of CUG trinucleotide repeats. Exp Neurol. 2008 Apr; 210(2):467-78.
Score: 0.062
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Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy. J Clin Invest. 2007 Oct; 117(10):2802-11.
Score: 0.061
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A reversal of misfortune for myotonic dystrophy? N Engl J Med. 2006 Oct 26; 355(17):1825-7.
Score: 0.057
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Transgenic mice expressing CUG-BP1 reproduce splicing mis-regulation observed in myotonic dystrophy. Hum Mol Genet. 2005 Jun 01; 14(11):1539-47.
Score: 0.052
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Multiple domains control the subcellular localization and activity of ETR-3, a regulator of nuclear and cytoplasmic RNA processing events. J Cell Sci. 2004 Jul 15; 117(Pt 16):3519-29.
Score: 0.049
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Insulin receptor splicing alteration in myotonic dystrophy type 2. Am J Hum Genet. 2004 Jun; 74(6):1309-13.
Score: 0.048
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RNA processing and human disease. Cell Mol Life Sci. 2000 Feb; 57(2):235-49.
Score: 0.036
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The relative strengths of SR protein-mediated associations of alternative and constitutive exons can influence alternative splicing. J Biol Chem. 1999 Oct 15; 274(42):29838-42.
Score: 0.035
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Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c. J Biol Chem. 1999 Apr 16; 274(16):10951-62.
Score: 0.034
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Alu insertion variants alter mRNA splicing. Nucleic Acids Res. 2019 01 10; 47(1):421-431.
Score: 0.033
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Defining pre-mRNA cis elements that regulate cell-specific splicing. Methods Mol Biol. 1999; 118:391-403.
Score: 0.033
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A 32-nucleotide exon-splicing enhancer regulates usage of competing 5' splice sites in a differential internal exon. Mol Cell Biol. 1995 Aug; 15(8):3979-88.
Score: 0.026