Connection

JOHN LYDON to Signal Transduction

This is a "connection" page, showing publications JOHN LYDON has written about Signal Transduction.
Connection Strength

1.621
  1. 90 YEARS OF PROGESTERONE: New insights into progesterone receptor signaling in the endometrium required for embryo implantation. J Mol Endocrinol. 2020 07; 65(1):T1-T14.
    View in: PubMed
    Score: 0.273
  2. The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. Dev Biol. 2009 Apr 01; 328(1):127-39.
    View in: PubMed
    Score: 0.124
  3. Progesterone signaling in oviductal epithelial cells modulates the immune response to support preimplantation embryonic development. Sci Adv. 2025 Apr 18; 11(16):eadt6113.
    View in: PubMed
    Score: 0.095
  4. Glandular defects in the mouse uterus with sustained activation of TGF-beta signaling is associated with altered differentiation of endometrial stromal cells and formation of stromal compartment. PLoS One. 2018; 13(12):e0209417.
    View in: PubMed
    Score: 0.061
  5. CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy. PLoS Genet. 2017 Mar; 13(3):e1006654.
    View in: PubMed
    Score: 0.054
  6. Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors. PLoS One. 2015; 10(6):e0128467.
    View in: PubMed
    Score: 0.048
  7. The p160/steroid receptor coactivator family: potent arbiters of uterine physiology and dysfunction. Biol Reprod. 2014 Nov; 91(5):122.
    View in: PubMed
    Score: 0.046
  8. Activated AKT pathway promotes establishment of endometriosis. Endocrinology. 2014 May; 155(5):1921-30.
    View in: PubMed
    Score: 0.044
  9. ?-Catenin activation contributes to the pathogenesis of adenomyosis through epithelial-mesenchymal transition. J Pathol. 2013 Oct; 231(2):210-22.
    View in: PubMed
    Score: 0.043
  10. Progesterone signaling inhibits cervical carcinogenesis in mice. Am J Pathol. 2013 Nov; 183(5):1679-1687.
    View in: PubMed
    Score: 0.043
  11. Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer. Mol Endocrinol. 2012 Sep; 26(9):1552-66.
    View in: PubMed
    Score: 0.039
  12. Differential modes of activation define orphan subclasses within the steroid/thyroid receptor superfamily. Gene Expr. 1992; 2(3):273-83.
    View in: PubMed
    Score: 0.038
  13. From the ranks of mammary progesterone mediators, RANKL takes the spotlight. Mol Cell Endocrinol. 2012 Jun 24; 357(1-2):91-100.
    View in: PubMed
    Score: 0.037
  14. The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science. 2011 Feb 18; 331(6019):912-6.
    View in: PubMed
    Score: 0.036
  15. A mouse transgenic approach to induce ?-catenin signaling in a temporally controlled manner. Transgenic Res. 2011 Aug; 20(4):827-40.
    View in: PubMed
    Score: 0.035
  16. Minireview: steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis. Endocrinology. 2011 Jan; 152(1):19-25.
    View in: PubMed
    Score: 0.035
  17. A mouse model to dissect progesterone signaling in the female reproductive tract and mammary gland. Genesis. 2010 Feb; 48(2):106-13.
    View in: PubMed
    Score: 0.033
  18. The pattern of beta-catenin responsiveness within the mammary gland is regulated by progesterone receptor. Development. 2007 Oct; 134(20):3703-12.
    View in: PubMed
    Score: 0.028
  19. Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids. 2003 Nov; 68(10-13):779-87.
    View in: PubMed
    Score: 0.022
  20. The NR2F2-HAND2 signaling axis regulates progesterone actions in the uterus at early pregnancy. Front Endocrinol (Lausanne). 2023; 14:1229033.
    View in: PubMed
    Score: 0.021
  21. Progesterone receptors in mammary gland development and tumorigenesis. J Mammary Gland Biol Neoplasia. 2003 Apr; 8(2):205-14.
    View in: PubMed
    Score: 0.021
  22. Deficiency of PARP-1 and PARP-2 in the mouse uterus results in decidualization failure and pregnancy loss. Proc Natl Acad Sci U S A. 2021 10 05; 118(40).
    View in: PubMed
    Score: 0.019
  23. Transforming growth factor beta signaling and decidual integrity in mice?. Biol Reprod. 2020 12 01; 103(6):1186-1198.
    View in: PubMed
    Score: 0.018
  24. Targeting progesterone signaling prevents metastatic ovarian cancer. Proc Natl Acad Sci U S A. 2020 12 15; 117(50):31993-32004.
    View in: PubMed
    Score: 0.018
  25. Increased FOXL2 expression alters uterine structures and functions?. Biol Reprod. 2020 10 29; 103(5):951-965.
    View in: PubMed
    Score: 0.017
  26. Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice. Cancer Sci. 2020 Oct; 111(10):3576-3587.
    View in: PubMed
    Score: 0.017
  27. The autophagy protein, FIP200 (RB1CC1) mediates progesterone responses governing uterine receptivity and decidualization?. Biol Reprod. 2020 04 15; 102(4):843-851.
    View in: PubMed
    Score: 0.017
  28. Uterine Gaq/11 signaling, in a progesterone-dependent manner, critically regulates the acquisition of uterine receptivity in the female mouse. FASEB J. 2019 08; 33(8):9374-9387.
    View in: PubMed
    Score: 0.016
  29. FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation. PLoS Genet. 2018 11; 14(11):e1007787.
    View in: PubMed
    Score: 0.015
  30. Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Mol Hum Reprod. 2017 09 01; 23(9):646-653.
    View in: PubMed
    Score: 0.014
  31. Conditional abrogation of transforming growth factor-? receptor 1 in PTEN-inactivated endometrium promotes endometrial cancer progression in mice. J Pathol. 2017 09; 243(1):89-99.
    View in: PubMed
    Score: 0.014
  32. A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function. Cell Rep. 2016 10 25; 17(5):1414-1425.
    View in: PubMed
    Score: 0.013
  33. Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis. Mol Endocrinol. 2016 May; 30(5):518-32.
    View in: PubMed
    Score: 0.013
  34. Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development. Oncotarget. 2016 Mar 22; 7(12):14885-97.
    View in: PubMed
    Score: 0.013
  35. Uterine ALK3 is essential during the window of implantation. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):E387-95.
    View in: PubMed
    Score: 0.012
  36. Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice. Cell Death Differ. 2016 Jan; 23(1):169-81.
    View in: PubMed
    Score: 0.012
  37. Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis. Oncogene. 2015 Oct; 34(43):5418-26.
    View in: PubMed
    Score: 0.012
  38. The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun; 10(6):e1004451.
    View in: PubMed
    Score: 0.011
  39. Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans. PLoS Genet. 2013 Nov; 9(11):e1003863.
    View in: PubMed
    Score: 0.011
  40. Paracrine-rescued lobulogenesis in chimeric outgrowths comprising progesterone-receptor-null mammary epithelium and redirected wild-type testicular cells. J Cell Sci. 2014 Jan 01; 127(Pt 1):27-32.
    View in: PubMed
    Score: 0.011
  41. Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet. 2013 Oct; 9(10):e1003900.
    View in: PubMed
    Score: 0.011
  42. BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest. 2013 Jun; 123(6):2539-50.
    View in: PubMed
    Score: 0.010
  43. Progesterone suppresses the mTOR pathway and promotes generation of induced regulatory T cells with increased stability. Eur J Immunol. 2012 Oct; 42(10):2683-96.
    View in: PubMed
    Score: 0.010
  44. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med. 2012 Jul; 18(7):1102-11.
    View in: PubMed
    Score: 0.010
  45. Progesterone receptors: a key for neuroprotection in experimental stroke. Endocrinology. 2012 Aug; 153(8):3747-57.
    View in: PubMed
    Score: 0.010
  46. Research resource: Genome-wide profiling of progesterone receptor binding in the mouse uterus. Mol Endocrinol. 2012 Aug; 26(8):1428-42.
    View in: PubMed
    Score: 0.010
  47. Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse. FASEB J. 2012 Jan; 26(1):282-94.
    View in: PubMed
    Score: 0.009
  48. Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology. 2011 Mar; 152(3):1047-56.
    View in: PubMed
    Score: 0.009
  49. WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse. FASEB J. 2011 Apr; 25(4):1176-87.
    View in: PubMed
    Score: 0.009
  50. Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse. Biol Reprod. 2010 May; 82(5):991-9.
    View in: PubMed
    Score: 0.008
  51. Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling. Biol Reprod. 2010 Apr; 82(4):783-90.
    View in: PubMed
    Score: 0.008
  52. Bone growth and turnover in progesterone receptor knockout mice. Endocrinology. 2008 May; 149(5):2383-90.
    View in: PubMed
    Score: 0.007
  53. In vivo analysis of progesterone receptor action in the uterus during embryo implantation. Semin Cell Dev Biol. 2008 Apr; 19(2):178-86.
    View in: PubMed
    Score: 0.007
  54. A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb; 22(2):344-60.
    View in: PubMed
    Score: 0.007
  55. Progesterone enhances branching morphogenesis in the mouse mammary gland by increased expression of Msx2. Oncogene. 2007 Nov 29; 26(54):7526-34.
    View in: PubMed
    Score: 0.007
  56. Bmp2 is critical for the murine uterine decidual response. Mol Cell Biol. 2007 Aug; 27(15):5468-78.
    View in: PubMed
    Score: 0.007
  57. Molecular mechanisms involved in progesterone receptor regulation of uterine function. J Steroid Biochem Mol Biol. 2006 Dec; 102(1-5):41-50.
    View in: PubMed
    Score: 0.007
  58. Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet. 2006 Oct; 38(10):1204-9.
    View in: PubMed
    Score: 0.007
  59. Hormonal defect in maspin heterozygous mice reveals a role of progesterone in pubertal ductal development. Mol Endocrinol. 2004 Sep; 18(9):2196-207.
    View in: PubMed
    Score: 0.006
  60. Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9744-9.
    View in: PubMed
    Score: 0.005
  61. Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol. 2002 Dec; 16(12):2675-91.
    View in: PubMed
    Score: 0.005
  62. Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15644-8.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.