YONGCHENG SONG to Histones
This is a "connection" page, showing publications YONGCHENG SONG has written about Histones.
Connection Strength
2.275
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Structure-activity relationship and antitumor activity of 1,4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP. Eur J Med Chem. 2022 Jul 05; 237:114407.
Score: 0.601
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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives. J Hematol Oncol. 2016 06 17; 9(1):49.
Score: 0.400
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Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer. Oncotarget. 2014 Nov 15; 5(21):10665-77.
Score: 0.358
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A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L. J Med Chem. 2013 Nov 27; 56(22):8972-83.
Score: 0.329
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Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha. Commun Biol. 2020 04 07; 3(1):165.
Score: 0.130
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Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1. PLoS One. 2017; 12(2):e0170301.
Score: 0.105
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Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia. J Hematol Oncol. 2016 Mar 12; 9:24.
Score: 0.098
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3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1. J Med Chem. 2016 Jan 14; 59(1):253-263.
Score: 0.097
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Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds. J Med Chem. 2015 Sep 10; 58(17):6899-6908.
Score: 0.095
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DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood. 2016 08 18; 128(7):971-81.
Score: 0.025
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DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy. PLoS One. 2014; 9(5):e98270.
Score: 0.022
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Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem. 2009 Dec 25; 284(52):36167-36174.
Score: 0.016